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https://www.readbyqxmd.com/read/29129021/the-effect-of-natural-or-simulated-altitude-training-on-high-intensity-intermittent-running-performance-in-team-sport-athletes-a-meta-analysis
#1
REVIEW
Michael J Hamlin, Catherine A Lizamore, Will G Hopkins
BACKGROUND: While adaptation to hypoxia at natural or simulated altitude has long been used with endurance athletes, it has only recently gained popularity for team-sport athletes. OBJECTIVE: To analyse the effect of hypoxic interventions on high-intensity intermittent running performance in team-sport athletes. METHODS: A systematic literature search of five journal databases was performed. Percent change in performance (distance covered) in the Yo-Yo intermittent recovery test (level 1 and level 2 were used without differentiation) in hypoxic (natural or simulated altitude) and control (sea level or normoxic placebo) groups was meta-analyzed with a mixed model...
November 11, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29067323/intermittent-hypoxic-hyperoxic-training-on-cognitive-performance-in-geriatric-patients
#2
Urike Bayer, Rudolf Likar, Georg Pinter, Haro Stettner, Susanne Demschar, Brigitte Trummer, Stefan Neuwersch, Oleg Glazachev, Martin Burtscher
INTRODUCTION: Intermittent hypoxic-hyperoxic training (IHHT) may complement a multimodal training intervention (MTI) for improving cognitive function and exercise tolerance in geriatric patients. METHODS: Thirty-four patients (64-92 years) participated in this randomized controlled trial. Before and after the 5- to 7-week intervention period (MTI + IHHT vs. MTI + ambient air), cognitive function was assessed by the Dementia-Detection Test (DemTect) and the Sunderland Clock-Drawing Test (CDT), and functional exercise capacity by the total distance of the 6-Minute Walk Test (6MWT)...
January 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29024137/do-male-athletes-with-already-high-initial-hemoglobin-mass-benefit-from-live-high-train-low-altitude-training
#3
Anna Hauser, Severin Troesch, Thomas Steiner, Franck Brocherie, Olivier Girard, Jonas J Saugy, Laurent Schmitt, Grégoire P Millet, Jon P Wehrlin
It has been proposed that athletes with high initial values of hemoglobin mass (Hbmass ) will have a lower Hbmass increase in response to 'live high-train low' (LHTL) altitude training. To verify this assumption, the relationship between initial absolute and relative Hbmass values and their respective Hbmass increase following LHTL in male endurance and team-sport athletes was investigated. Overall, 58 male athletes (35 well-trained endurance athletes and 23 elite male field hockey players) undertook an LHTL training camp with similar hypoxic doses (200-230 h)...
October 11, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29023329/living-and-training-at-825m-for-8-weeks-supplemented-with-intermittent-hypoxic-training-at-3000m-improves-blood-parameters-and-running-performance
#4
Preetiwat Wonnabussapawich, Michael J Hamlin, Catherine A Lizamore, Nuttaset Manimmanakorn, Naruemon Leelayuwat, Orathai Tunkamnerdthai, Worrawut Thuwakum, Apiwan Manimmanakorn
We aimed to investigate the effect of an 8-week low-altitude training block supplemented with intermittent hypoxic training, on blood and performance parameters in soccer players. Forty university-level male soccer players were separated into altitude (n = 20, 825m) or sea level (n = 20, 125m) groups. Before (1-2 days prior) and after (1 and 14 days post) training, players were asked to give a resting venous blood sample and complete a series of performance tests. Compared to sea level, the altitude group increased erythropoietin, red cell count and hematocrit 1 day post training (42...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28988307/effects-of-normoxic-and-hypoxic-exercise-regimens-on-lymphocyte-apoptosis-induced-by-oxidative-stress-in-sedentary-males
#5
Jong-Shyan Wang, Yi-Ching Chen, Wan-Ling Chen, Chin-Pu Lin
PURPOSE: Oxidative stress-induced lymphocyte apoptosis is linked to hypoxemic individuals suffering from cardiopulmonary disorders or exposed to hypoxic environments. What kind of the exercise strategy under hypoxic condition improves exercise performance and simultaneously minimizes lymphocyte dysfunction caused by oxidative stress has not yet been established. This study elucidates how various exercises regimens with/without hypoxia affect lymphocyte apoptosis induced by oxidative stress...
October 7, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28965346/impact-of-5-days-of-sprint-training-in-hypoxia-on-performance-and-muscle-energy-substances
#6
Nobukazu Kasai, Chihiro Kojima, Daichi Sumi, Hideyuki Takahashi, Kazushige Goto, Yasuhiro Suzuki
The present study was designed to determine the effect of 5 consecutive days of repeated sprint training under hypoxia on anaerobic performance and energy substances. Nineteen male sprinters performed repeated sprints for 5 consecutive days under a hypoxic (HYPO; fraction of inspired oxygen [FiO2], 14.5%) or normoxic (NOR; FiO2, 20.9%) condition. Before and after the training period, 10-s maximal sprint, repeated sprint ability (5×6-s sprints), 30-s maximal sprint, and maximal oxygen uptake (VO2max) tests were conducted...
October 1, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28929623/influence-of-combined-iron-supplementation-and-simulated-hypoxia-on-the-haematological-module-of-the-athlete-biological-passport
#7
Laura A Garvican-Lewis, Victor L Vuong, Andrew D Govus, Yorck Olaf Schumacher, David Hughes, Greg Lovell, Daniel Eichner, Christopher J Gore
The integrity of Athlete Biological Passport (ABP) is underpinned by understanding normal fluctuations of its biomarkers to environmental or medical conditions, e.g. altitude training or iron deficiency. The combined impact of altitude and iron supplementation on the ABP was evaluated in endurance-trained athletes (n=34) undertaking 3-weeks of simulated live-high: train-low (14 h.d(-1) , 3000m). Athletes received either oral, intravenous (IV) or placebo iron supplementation, commencing two weeks prior and continuing throughout hypoxic exposure...
September 19, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28912649/does-live-high-train-low-and-high-hypoxic-training-alter-running-mechanics-in-elite-team-sport-players
#8
Olivier Girard, Grégoire P Millet, Jean-Benoit Morin, Franck Brocherie
This study aimed to investigate if "Live High-Train Low (and High)" hypoxic training alters constant-velocity running mechanics. While residing under normobaric hypoxia (≥14 h·d(-1); FiO2 14.5-14.2%) for 14 days, twenty field hockey players performed, in addition to their usual training in normoxia, six sessions (4 × 5 × 5-s maximal sprints; 25 s passive recovery; 5 min rest) under either normobaric hypoxia (FiO2 ~14.5%, n = 9) or normoxia (FiO2 20.9%, n = 11). Before and immediately after the intervention, their running pattern was assessed at 10 and 15 km·h(-1) as well as during six 30-s runs at ~20 km·h(-1) with 30-s passive recovery on an instrumented motorised treadmill...
September 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28846046/the-use-of-simulated-altitude-techniques-for-beneficial-cardiovascular-health-outcomes-in-nonathletic-sedentary-and-clinical-populations-a-literature-review
#9
Catherine A Lizamore, Michael J Hamlin
Lizamore, Catherine A., and Michael J. Hamlin. The use of simulated altitude techniques for beneficial cardiovascular health outcomes in nonathletic, sedentary, and clinical populations: A literature review. High Alt Med Biol 00:000-000, 2017. BACKGROUND: The reportedly beneficial improvements in an athlete's physical performance following altitude training may have merit for individuals struggling to meet physical activity guidelines. AIM: To review the effectiveness of simulated altitude training methodologies at improving cardiovascular health in sedentary and clinical cohorts...
August 28, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28840770/predicting-tumor-hypoxia-in-non-small-cell-lung-cancer-by-combining-ct-fdg-pet-and-dynamic-contrast-enhanced-ct
#10
Aniek J G Even, Bart Reymen, Matthew D La Fontaine, Marco Das, Arthur Jochems, Felix M Mottaghy, José S A Belderbos, Dirk De Ruysscher, Philippe Lambin, Wouter van Elmpt
BACKGROUND: Most solid tumors contain inadequately oxygenated (i.e., hypoxic) regions, which tend to be more aggressive and treatment resistant. Hypoxia PET allows visualization of hypoxia and may enable treatment adaptation. However, hypoxia PET imaging is expensive, time-consuming and not widely available. We aimed to predict hypoxia levels in non-small cell lung cancer (NSCLC) using more easily available imaging modalities: FDG-PET/CT and dynamic contrast-enhanced CT (DCE-CT). MATERIAL AND METHODS: For 34 NSCLC patients, included in two clinical trials, hypoxia HX4-PET/CT, planning FDG-PET/CT and DCE-CT scans were acquired before radiotherapy...
August 25, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28829838/post-exercise-serum-hepcidin-levels-were-unaffected-by-hypoxic-exposure-during-prolonged-exercise-sessions
#11
Kazushige Goto, Daichi Sumi, Chihiro Kojima, Aya Ishibashi
The purpose of the present study was to determine the influence of hypoxic exposure during prolonged endurance exercise sessions (79 min in total) on post-exercise hepcidin levels in trained male endurance athletes. Ten endurance athletes (mean ± standard deviation; height: 169.8 ± 7.1 cm, weight: 57.1 ± 5.0 kg) conducted two endurance exercise sessions under either a normobaric hypoxic condition [inspired O2 fraction (FiO2) = 14.5%] or a normoxic condition (FiO2 = 20.9%). Exercise consisted of 10 × 3 min running on a treadmill at 95% of maximal oxygen uptake ([Formula: see text]) with 60s of active rest at 60% of [Formula: see text]...
2017: PloS One
https://www.readbyqxmd.com/read/28828549/postnatal-hypoxia-evokes-persistent-changes-within-the-male-rat-s-dopaminergic-system
#12
Michael J Decker, Karra A Jones, Glenda L Keating, David B Rye
PURPOSE: Hypoxic insults occurring during the perinatal period remain the leading cause of permanent brain impairment. Severe cognitive and motor dysfunction, as seen in cerebral palsy, will occur in 4-10% of post-hypoxic newborns. Subtle cognitive impairment, apparent in disorders of minimal brain dysfunction will occur in > 3 million post-hypoxic newborns. Analyses of post-hypoxic rodent brains reveal reduced extracellular levels of dopamine, a key neurotransmitter of vigilance, execute function, and behavior...
August 22, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28800288/population-based-study-of-the-national-implementation-of-therapeutic-hypothermia-in-infants-with-hypoxic-ischemic-encephalopathy
#13
Juan Arnaez, Alfredo García-Alix, Gemma Arca, Sonia Caserío, Eva Valverde, M Teresa Moral, Isabel Benavente-Fernández, Simón Lubián-López
Data on the incidence of hypoxic-ischemic encephalopathy (HIE) in the first 6 hours of life together with the implementation of therapeutic hypothermia (TH) are relevant to delineate actions to achieve the lowest rates of neonatal mortality, morbidity, and long-term impact on health associated with HIE. This is population-based national survey study, including newborns ≥35 weeks of gestation with moderate-to-severe HIE from all level III neonatal care units, to provide the incidence of HIE for the period 2012-2013, and the implementation of TH up to June 2015 in Spain...
August 11, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28798201/remote-ischemic-preconditioning-does-not-prevent-acute-mountain-sickness-after-rapid-ascent-to-3450-m
#14
Marc M Berger, Franziska Macholz, Lukas Lehmann, Daniel Dankl, Marcel Hochreiter, Bernhard Bacher, Peter Bärtsch, Heimo Mairbäurl
Remote ischemic preconditioning (RIPC) has been shown to protect remote organs, such as the brain and the lung, from damage induced by subsequent hypoxia or ischemia. Acute mountain sickness (AMS) is a syndrome of non-specific neurologic symptoms and in high altitude pulmonary edema excessive hypoxic pulmonary vasoconstriction (HPV) plays a pivotal role. We hypothesized that RIPC protects the brain from AMS and attenuates the magnitude of HPV after rapid ascent to 3450 m. Forty non-acclimatized volunteers were randomized into 2 groups...
August 10, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28764944/-incidence-of-hypoxic-ischaemic-encephalopathy-and-use-of-therapeutic-hypothermia-in-spain
#15
Juan Arnaez, Alfredo García-Alix, Gemma Arca, Eva Valverde, Sonia Caserío, M Teresa Moral, Isabel Benavente-Fernández, Simón Lubián-López
INTRODUCTION: There are no data on the incidence of hypoxic-ischaemic encephalopathy (HIE) and the implementation of therapeutic hypothermia (TH) in Spain. METHODS: This is a cross-sectional, national study, performed using an on-line questionnaire targeting level III neonatal care units in Spain. Participants were requested to provide data of all newborns ≥ 35 weeks of gestational age diagnosed with moderate-severe HIE over a two year-period (2012-2013), and of the implementation of TH up to June 2015...
July 29, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28763443/intermittent-hypoxic-training-improves-anaerobic-performance-in-competitive-swimmers-when-implemented-into-a-direct-competition-mesocycle
#16
RANDOMIZED CONTROLLED TRIAL
Miłosz Czuba, Robert Wilk, Jakub Karpiński, Małgorzata Chalimoniuk, Adam Zajac, Józef Langfort
The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on anaerobic and aerobic capacity and swimming performance in well-trained swimmers. Sixteen male swimmers were randomly divided into a hypoxia (H) group (n = 8), which trained in a normobaric hypoxia environment, and a control (C) group (n = 8), which exercised under normoxic conditions. However, one participant left the study without explanation. During the experiment group H trained on land twice per week in simulated hypoxia (FiO2 = 15...
2017: PloS One
https://www.readbyqxmd.com/read/28762914/-adaptation-to-intermittent-hypoxia-hyperoxia-in-the-rehabilitation-of-patients-with-ischemic-heart-disease-exercise-tolerance-and-quality-of-life
#17
A L Syrkin, O S Glazachev, F Y Kopylov, E N Dudnik, E E Zagaynaya, D S Tuter
AIM: to assess effect of interval hypoxic-hyperoxic training (IT) on exercise tolerance and quality of life of patients with ischemic heart disease (IHD) receiving optimal medical therapy, as well as the safety of IHHT use. METHODS: Patients with stable IHD with functional class II and III angina (n=46) were randomized into two groups: IHHT (n=27, 15 treatments in 3 weeks), and IHHT imitation (n=19). Cardiopulmonary stress test was performed to evaluate the following parameters of exercise tolerance: peak oxygen consumption (VO2peak, VO2peak/kg), % of predicted peak oxygen consumption (%VO2 peak) and anaerobic threshold (VO2AT)...
May 2017: Kardiologiia
https://www.readbyqxmd.com/read/28752919/acute-physiological-and-perceptual-responses-to-high-load-resistance-exercise-in-hypoxia
#18
Brendan R Scott, Katie M Slattery, Dean V Sculley, Scott M Smith, Jeremiah J Peiffer, Ben J Dascombe
This study assessed whether hypoxia during high-load resistance exercise could enhance the acute physiological responses related to muscular development. Twelve trained men performed exercise in three conditions: normoxia (fraction of inspired oxygen [FI O2 ] = 21%), moderate-level hypoxia (FI O2  = 16%) and high-level hypoxia (FI O2  = 13%). Exercise comprised high-load squats and deadlifts (5 × 5 using 80% of 1-repetition maximum with 180-s rest). Muscle oxygenation and activation were monitored during exercise...
July 28, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28744647/antioxidant-and-antiamnestic-effects-of-potassium-comenate-and-comenic-acid-under-conditions-of-normobaric-hypoxia-with-hypercapnia
#19
L V Shurygina, E I Zlishcheva, A N Kravtsova, A A Kravtsov
Potassium comenate and comenic acid exhibit manifest and virtually identical antioxidant activity under conditions of hypoxia with hypercapnia. The effects of these drugs on conditioned reflex training with positive reinforcement differ significantly. Potassium comenate promotes retention of the learning capacity and memory in hypoxic rats at the level of intact control, that is, exhibits a pronounced protective antiamnestic effect, while comenic acid only facilitates training of the conditioned reflex with positive reinforcement...
July 26, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28738295/does-the-effect-of-one-day-simulation-team-training-in-obstetric-emergencies-decline-within-one-year-a-post-hoc-analysis-of-a-multicentre-cluster-randomised-controlled-trial
#20
J van de Ven, A F Fransen, E Schuit, P J van Runnard Heimel, B W Mol, S G Oei
Does the effect of one-day simulation team training in obstetric emergencies decline within one year? A post-hoc analysis of a multicentre cluster randomised controlled trial. J van de Ven, AF Fransen, E Schuit, PJ van Runnard Heimel, BW Mol, SG Oei OBJECTIVE: To investigate whether the effect of a one-day simulation-based obstetric team training on patient outcome changes over time. STUDY DESIGN: Post-hoc analysis of a multicentre, open, randomised controlled trial that evaluated team training in obstetrics (TOSTI study)...
September 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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