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Hypoxic training

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https://www.readbyqxmd.com/read/28315193/resistance-training-using-different-hypoxic-training-strategies-a-basis-for-hypertrophy-and-muscle-power-development
#1
REVIEW
Belén Feriche, Amador García-Ramos, Antonio J Morales-Artacho, Paulino Padial
The possible muscular strength, hypertrophy, and muscle power benefits of resistance training under environmental conditions of hypoxia are currently being investigated.Nowadays, resistance training in hypoxia constitutes a promising new training strategy for strength and muscle gains. The main mechanisms responsible for these effects seem to be related to increased metabolite accumulation due to hypoxia. However, no data are reported in the literature to describe and compare the efficacy of the different hypertrophic resistance training strategies in hypoxia...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28280973/determinants-of-curvature-constant-w-of-the-power-duration-relationship-under-normoxia-and-hypoxia-the-effect-of-pre-exercise-alkalosis
#2
Sanjoy K Deb, Lewis A Gough, S Andy Sparks, Lars R McNaughton
PURPOSE: This study investigated the effect of induced alkalosis on the curvature constant (W') of the power-duration relationship under normoxic and hypoxic conditions. METHODS: Eleven trained cyclists (mean ± SD) Age: 32 ± 7.2 years; body mass (bm): 77.0 ± 9.2 kg; VO2peak: 59.2 ± 6.8 ml·kg(-1)·min(-1) completed seven laboratory visits which involved the determination of individual time to peak alkalosis following sodium bicarbonate (NaHCO3) ingestion, an environment specific ramp test (e...
March 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28278461/automatic-quantification-of-tumour-hypoxia-from-multi-modal-microscopy-images-using-weakly-supervised-learning-methods
#3
Gustavo Carneiro, Tingying Peng, Christine Bayer, Nassir Navab
In recently published clinical trial results, hypoxia-modified therapies have shown to provide more positive outcomes to cancer patients, compared with standard cancer treatments. The development and validation of these hypoxia-modified therapies depend on an effective way of measuring tumour hypoxia, but a standardised measurement is currently unavailable in clinical practice. Different types of manual measurements have been proposed in clinical research, but in this paper we focus on a recently published approach that quantifies the number and proportion of hypoxic regions using high resolution (immuno- ) fluorescence (IF) and hematoxylin and eosin (HE) stained images of a histological specimen of a tumour...
March 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28278387/12-days-of-altitude-exposure-at-1800m-does-not-increase-resting-metabolic-rate-in-elite-rowers
#4
Amy L Woods, Laura A Garvican-Lewis, Anthony Rice, Kevin Grant Thompson
Four elite rowers completed a twelve-day altitude training camp living at 1800m, and training at 1800m and 915m, to assess changes in resting metabolic rate (RMR). RMR and body composition were assessed PRE and POST-camp. Downward trends in RMR and body composition were observed post-altitude: absolute RMR (percent change: -5.2%), relative RMR (-4.6%), body mass (-1.2%), and fat mass (-4.1%), likely related to the hypoxic stimulus and an imbalance between training load and energy intake.
March 9, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28277432/physiological-factors-associated-with-declining-repeated-sprint-performance-in-hypoxia
#5
Hannes Gatterer, Verena Menz, Christian Untersteiner, Kultida Klarod, Martin Burtscher
Performance loss in hypoxia might not only be caused by reduced oxygen availability, but might also be influenced by other factors, as for example oxidative stress, perceived exertion or breathing patterns. This study aimed to investigate the influence of these factors on running performance during hypoxic and normoxic shuttle-run sprinting. Eight male amateur soccer players performed shuttle-run sprints in hypoxia (FiO2∼14.8%) and normoxia (random order). Each session comprised 3-sets of 5x10s back and forth sprints (4...
March 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28273332/comparison-between-model-predicted-tumor-oxygenation-dynamics-and-vascular-flow-related-doppler-indices
#6
Antonella Belfatto, Ailyn M Vidal Urbinati, Delia Ciardo, Dorella Franchi, Federica Cattani, Roberta Lazzari, Barbara A Jereczek-Fossa, Roberto Orecchia, Guido Baroni, Pietro Cerveri
PURPOSE: Mathematical modeling is a powerful and flexible method to investigate complex phenomena. It discloses the possibility of reproducing expensive as well as invasive experiments in a safe environment with limited costs. This makes it suitable to mimic tumor evolution and response to radiotherapy although the reliability of the results remains an issue. Complexity reduction is therefore a critical aspect in order to be able to compare model outcomes to clinical data. Among the factors affecting treatment efficacy, tumor oxygenation is known to play a key role in radiotherapy response...
March 8, 2017: Medical Physics
https://www.readbyqxmd.com/read/28270770/maximal-oxygen-uptake-is-achieved-in-hypoxia-but-not-normoxia-during-an-exhaustive-severe-intensity-run
#7
Matthew I Black, Christopher R Potter, Jo Corbett, Cain C T Clark, Stephen B Draper
Highly aerobically trained individuals are unable to achieve maximal oxygen uptake ([Formula: see text]) during exhaustive running lasting ~2 min, instead [Formula: see text] plateaus below [Formula: see text] after ~1 min. Hypoxia offers the opportunity to study the ([Formula: see text]) response to an exhaustive run relative to a hypoxia induced reduction in [Formula: see text]. The aim of this study was to explore whether there is a difference in the percentage of [Formula: see text] achieved (during a 2 min exhaustive run) in normoxia and hypoxia...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28260202/biochemical-responses-and-physical-performance-during-high-intensity-resistance-circuit-training-in-hypoxia-and-normoxia
#8
Domingo J Ramos-Campo, Jacobo A Rubio-Arias, Stéphane Dufour, Linda Chung, Vicente Ávila-Gandía, Pedro E Alcaraz
PURPOSE: The aim of this study was to analyze the effect of hypoxia on metabolic and acid-base balance, blood oxygenation, electrolyte, and half-squat performance variables during high-resistance circuit (HRC) training. METHODS: Twelve resistance-trained subjects participated in this study. After a 6RM testing session, participants performed three randomized trials of HRC: normoxia (NORM: FiO2 = 0.21), moderate hypoxia (MH: FiO2 = 0.16), or high hypoxia (HH: FiO2 = 0...
March 4, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28248531/baseline-values-of-cardiovascular-and-respiratory-parameters-predict-response-to-acute-hypoxia-in-young-healthy-men
#9
V N Melnikov, S G Krivoschekov, V E Divert, T G Komlyagina, N S Consedine
The majority of the available works have studied distinct hypoxic responses of respiratory and cardiovascular systems. This study examines how these systems interact while responding to hypoxia and whether baseline metrics moderate reactions to a hypoxic challenge. Central hemodynamic, aortic wave reflection, and gas exchange parameters were measured in 27 trained young men before and after 10-min normobaric isocapnic hypoxia (10 % O2). Associations were assessed by correlation and multiple regression analyses...
February 28, 2017: Physiological Research
https://www.readbyqxmd.com/read/28223938/hypoxic-repeat-sprint-training-improves-rugby-player-s-repeated-sprint-but-not-endurance-performance
#10
Michael J Hamlin, Peter D Olsen, Helen C Marshall, Catherine A Lizamore, Catherine A Elliot
This study aims to investigate the performance changes in 19 well-trained male rugby players after repeat-sprint training (six sessions of four sets of 5 × 5 s sprints with 25 s and 5 min of active recovery between reps and sets, respectively) in either normobaric hypoxia (HYP; n = 9; FIO2 = 14.5%) or normobaric normoxia (NORM; n = 10; FIO2 = 20.9%). Three weeks after the intervention, 2 additional repeat-sprint training sessions in hypoxia (FIO2 = 14.5%) was investigated in both groups to gauge the efficacy of using "top-up" sessions for previously hypoxic-trained subjects and whether a small hypoxic dose would be beneficial for the previously normoxic-trained group...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28209739/myocardial-ischemic-tolerance-in-rats-subjected-to-endurance-exercise-training-during-adaptation-to-chronic-hypoxia
#11
Petra Alánová, Anna Chytilová, Jan Neckář, Jaroslav Hrdlička, Petra Míčová, Kristýna Holzerová, Markéta Hlaváčková, Kristýna Macháčková, František Papoušek, Jana Vašinová, Daniel Benák, Olga Nováková, František Kolář
Chronic hypoxia and exercise are natural stimuli that confer sustainable cardioprotection against ischemia/reperfusion (I/R) injury but it is unknown whether they can act in synergy to enhance ischemic resistance. Inflammatory response mediated by tumor necrosis factor-α (TNF-α) plays a role in the infarct size-limitation by continuous normobaric hypoxia (CNH) whereas exercise is associated with anti-inflammatory effects. This study was conducted to determine whether exercise training performed under conditions of CNH (12% O2) affects myocardial ischemic resistance with respect to inflammatory and redox status...
February 16, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28185577/artificial-neural-network-classifier-predicts-neuroblastoma-patients-outcome
#12
Davide Cangelosi, Simone Pelassa, Martina Morini, Massimo Conte, Maria Carla Bosco, Alessandra Eva, Angela Rita Sementa, Luigi Varesio
BACKGROUND: More than fifty percent of neuroblastoma (NB) patients with adverse prognosis do not benefit from treatment making the identification of new potential targets mandatory. Hypoxia is a condition of low oxygen tension, occurring in poorly vascularized tissues, which activates specific genes and contributes to the acquisition of the tumor aggressive phenotype. We defined a gene expression signature (NB-hypo), which measures the hypoxic status of the neuroblastoma tumor. We aimed at developing a classifier predicting neuroblastoma patients' outcome based on the assessment of the adverse effects of tumor hypoxia on the progression of the disease...
November 8, 2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/28180081/automatic-quantification-of-ischemic-injury-on-diffusion-weighted-mri-of-neonatal-hypoxic-ischemic-encephalopathy
#13
Keelin Murphy, Niek E van der Aa, Simona Negro, Floris Groenendaal, Linda S de Vries, Max A Viergever, Geraldine B Boylan, Manon J N L Benders, Ivana Išgum
A fully automatic method for detection and quantification of ischemic lesions in diffusion-weighted MR images of neonatal hypoxic ischemic encephalopathy (HIE) is presented. Ischemic lesions are manually segmented by two independent observers in 1.5 T data from 20 subjects and an automatic algorithm using a random forest classifier is developed and trained on the annotations of observer 1. The algorithm obtains a median sensitivity and specificity of 0.72 and 0.99 respectively. F1-scores are calculated per subject for algorithm performance (median = 0...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28150471/the-effect-of-4-weeks-fixed-and-mixed-intermittent-hypoxic-training-iht-on-respiratory-metabolic-and-acid-base-response-of-capillary-blood-during-submaximal-bicycle-exercise-in-male-elite-taekwondo-players
#14
Hun-Young Park, Sub Sunoo, Sang-Seok Nam
Purpose: The purpose of our study was to determine the effectiveness of 4 weeks fixed and mixed intermittent hypoxic training (IHT) and its difference from exercise training at sea-level on exercise load, respiratory metabolic and acid-base response of capillary blood during 80% maximal heart rate (HRmax) bicycle exercise in male elite Taekwondo players. Methods: Male elite Taekwondo players (n = 25 out of 33) were randomly assigned to training at sea-level (n = 8, control group), training at 16...
December 31, 2016: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28149414/neuroendocrine-responses-and-body-composition-changes-following-resistance-training-under-normobaric-hypoxia
#15
Jakub Chycki, Miłośz Czuba, Artur Gołaś, Adam Zając, Olga Fidos-Czuba, Adrian Młynarz, Wojciech Smółka
The aim of the present study was to evaluate the effects of a 6 week resistance training protocol under hypoxic conditions (FiO2 = 12.9%, 4000 m) on muscle hypertrophy. The project included 12 resistance trained male subjects, randomly divided into two experimental groups. Group 1 (n = 6; age 21 ± 2.4 years; body height [BH] 178.8 ± 7.3 cm; body mass [BM] 80.6 ± 12.3 kg) and group 2 (n = 6; age 22 ± 1.5 years; BH 177.8 ± 3.7cm; BM 81.1 ± 7.5 kg). Each group performed resistance exercises alternately under normoxic and hypoxic conditions (4000 m) for 6 weeks...
December 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28135217/short-term-hypoxic-exposure-and-training-improve-maximal-anaerobic-running-test-performance
#16
Marie Oriishi, Takeo Matsubayashi, Takashi Kawahara, Yasuhiro Suzuki
The purpose of this study was to examine the effectiveness of short-term hypoxic exposure and training in the performance of competitive 400 m or 800 m runners. Fifteen female competitive 400 m and 800 m runners volunteered to participate and were assigned to either the hypoxic (n = 7) or normoxic (n = 8) group. The subjects completed 6 days of training. The hypoxic group trained and slept in normobaric hypoxia, with oxygen concentrations of 14.4% and 16.5% for training and sleep, respectively. The normoxic group trained and slept at sea level...
January 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28090139/the-blood-antioxidant-defence-capacity-during-intermittent-hypoxic-training-in-elite-swimmers
#17
S Poprzęcki, M Czuba, A Zając, J Karpiński, R Wilk, G Bril, A Maszczyk, M Toborek
The main objective of this study was to examine the chronic effect of simulated intermittent normobaric hypoxia on blood antioxidant defence capacity in swimmers. The study included 14 male and 14 female competitive swimmers performing part of land training under simulated intermittent normobaric hypoxia (O2 = 15.5%) or in normoxia. Land interval training took place twice per week, with a total of 8 training units during the study, performed with individualized intensity. The activities of blood antioxidant enzymes did not change significantly during the first and last training unit in the hypoxic and normoxic group...
December 2016: Biology of Sport
https://www.readbyqxmd.com/read/28061925/hypoxia-occurrence-in-a-military-aviator-below-3048-m
#18
Lesli R Tristan
INTRODUCTION: Despite technological advances, hypoxia remains a concern in aviation. Hypoxia can present with a vast array of symptoms that are unique to each aviator. Military aviators undergo hypoxia awareness trainings to learn their unique constellation of hypoxia symptoms. CASE REPORT: This case report describes a military aviator who was flying in a B1 when the cabin depressurized. While performing the emergency checklist, the aviator was moving about the cabin and began to experience hypoxia symptoms...
January 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28052320/reliability-in-cardiotocography-interpretation-impact-of-extended-on-site-education-in-addition-to-web-based-learning-an-observational-study
#19
Erika Gyllencreutz, Ingela Hulthén Varli, Pelle G Lindqvist, Malin Holzmann
INTRODUCTION: Previous studies have shown poor reproducibility in cardiotocography (CTG) interpretation. Studies evaluating the Swedish web-based CTG-education program have not proven to increase accurate CTG assessments. The aim of this study was to evaluate whether an extended education can improve inter- and intra-observer reliability in CTG interpretation. MATERIAL AND METHODS: Six obstetricians from two different departments interpreted 106 CTG tracings at two occasions...
January 4, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28025662/the-effect-of-a-live-high-train-high-exercise-regimen-on-behavioural-temperature-regulation
#20
Shawnda A Morrison, Urša Ciuha, Daniela Zavec-Pavlinić, Ola Eiken, Igor B Mekjavic
PURPOSE: Acute hypoxia alters the threshold for sensation of cutaneous thermal stimuli. We hypothesised that hypoxia-induced alterations in cutaneous temperature sensation may lead to modulation of the perception of temperature, ultimately influencing behavioural thermoregulation and that the magnitude of this effect could be influenced by daily physical training. METHODS: Fourteen men were confined 10 days to a normobaric hypoxic environment (PIO2 = 88.2 ± 0...
December 26, 2016: European Journal of Applied Physiology
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