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Hypoxic training

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https://www.readbyqxmd.com/read/28800288/population-based-study-of-the-national-implementation-of-therapeutic-hypothermia-in-infants-with-hypoxic-ischemic-encephalopathy
#1
Juan Arnaez, Alfredo García-Alix, Gemma Arca, Sonia Caserío, Eva Valverde, M Teresa Moral, Isabel Benavente-Fernández, Simón Lubián-López
Data on the incidence of hypoxic-ischemic encephalopathy (HIE) in the first 6 hours of life together with the implementation of therapeutic hypothermia (TH) are relevant to delineate actions to achieve the lowest rates of neonatal mortality, morbidity, and long-term impact on health associated with HIE. This is population-based national survey study, including newborns ≥35 weeks of gestation with moderate-to-severe HIE from all level III neonatal care units, to provide the incidence of HIE for the period 2012-2013, and the implementation of TH up to June 2015 in Spain...
August 11, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28798201/remote-ischemic-preconditioning-does-not-prevent-acute-mountain-sickness-after-rapid-ascent-to-3450-m
#2
Marc M Berger, Franziska Macholz, Lukas Lehmann, Daniel Dankl, Marcel Hochreiter, Bernhard Bacher, Peter Bärtsch, Heimo Mairbäurl
Remote ischemic preconditioning (RIPC) has been shown to protect remote organs, such as the brain and the lung, from damage induced by subsequent hypoxia or ischemia. Acute mountain sickness (AMS) is a syndrome of non-specific neurologic symptoms and in high altitude pulmonary edema excessive hypoxic pulmonary vasoconstriction (HPV) plays a pivotal role. We hypothesized that RIPC protects the brain from AMS and attenuates the magnitude of HPV after rapid ascent to 3450 m. Forty non-acclimatized volunteers were randomized into 2 groups...
August 10, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28764944/-incidence-of-hypoxic-ischaemic-encephalopathy-and-use-of-therapeutic-hypothermia-in-spain
#3
Juan Arnaez, Alfredo García-Alix, Gemma Arca, Eva Valverde, Sonia Caserío, M Teresa Moral, Isabel Benavente-Fernández, Simón Lubián-López
INTRODUCTION: There are no data on the incidence of hypoxic-ischaemic encephalopathy (HIE) and the implementation of therapeutic hypothermia (TH) in Spain. METHODS: This is a cross-sectional, national study, performed using an on-line questionnaire targeting level III neonatal care units in Spain. Participants were requested to provide data of all newborns ≥ 35 weeks of gestational age diagnosed with moderate-severe HIE over a two year-period (2012-2013), and of the implementation of TH up to June 2015...
July 29, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28763443/intermittent-hypoxic-training-improves-anaerobic-performance-in-competitive-swimmers-when-implemented-into-a-direct-competition-mesocycle
#4
Miłosz Czuba, Robert Wilk, Jakub Karpiński, Małgorzata Chalimoniuk, Adam Zajac, Józef Langfort
The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on anaerobic and aerobic capacity and swimming performance in well-trained swimmers. Sixteen male swimmers were randomly divided into a hypoxia (H) group (n = 8), which trained in a normobaric hypoxia environment, and a control (C) group (n = 8), which exercised under normoxic conditions. However, one participant left the study without explanation. During the experiment group H trained on land twice per week in simulated hypoxia (FiO2 = 15...
2017: PloS One
https://www.readbyqxmd.com/read/28762914/-adaptation-to-intermittent-hypoxia-hyperoxia-in-the-rehabilitation-of-patients-with-ischemic-heart-disease-exercise-tolerance-and-quality-of-life
#5
A L Syrkin, O S Glazachev, F Y Kopylov, E N Dudnik, E E Zagaynaya, D S Tuter
AIM: to assess effect of interval hypoxic-hyperoxic training (IT) on exercise tolerance and quality of life of patients with ischemic heart disease (IHD) receiving optimal medical therapy, as well as the safety of IHHT use. METHODS: Patients with stable IHD with functional class II and III angina (n=46) were randomized into two groups: IHHT (n=27, 15 treatments in 3 weeks), and IHHT imitation (n=19). Cardiopulmonary stress test was performed to evaluate the following parameters of exercise tolerance: peak oxygen consumption (VO2peak, VO2peak/kg), % of predicted peak oxygen consumption (%VO2 peak) and anaerobic threshold (VO2AT)...
May 2017: Kardiologiia
https://www.readbyqxmd.com/read/28752919/acute-physiological-and-perceptual-responses-to-high-load-resistance-exercise-in-hypoxia
#6
Brendan R Scott, Katie M Slattery, Dean V Sculley, Scott M Smith, Jeremiah J Peiffer, Ben J Dascombe
This study assessed whether hypoxia during high-load resistance exercise could enhance the acute physiological responses related to muscular development. Twelve trained men performed exercise in three conditions: normoxia (fraction of inspired oxygen [FI O2 ] = 21%), moderate-level hypoxia (FI O2  = 16%) and high-level hypoxia (FI O2  = 13%). Exercise comprised high-load squats and deadlifts (5 × 5 using 80% of 1-repetition maximum with 180-s rest). Muscle oxygenation and activation were monitored during exercise...
July 28, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28744647/antioxidant-and-antiamnestic-effects-of-potassium-comenate-and-comenic-acid-under-conditions-of-normobaric-hypoxia-with-hypercapnia
#7
L V Shurygina, E I Zlishcheva, A N Kravtsova, A A Kravtsov
Potassium comenate and comenic acid exhibit manifest and virtually identical antioxidant activity under conditions of hypoxia with hypercapnia. The effects of these drugs on conditioned reflex training with positive reinforcement differ significantly. Potassium comenate promotes retention of the learning capacity and memory in hypoxic rats at the level of intact control, that is, exhibits a pronounced protective antiamnestic effect, while comenic acid only facilitates training of the conditioned reflex with positive reinforcement...
July 26, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28738295/does-the-effect-of-one-day-simulation-team-training-in-obstetric-emergencies-decline-within-one-year-a-post-hoc-analysis-of-a-multicentre-cluster-randomised-controlled-trial
#8
J van de Ven, A F Fransen, E Schuit, P J van Runnard Heimel, B W Mol, S G Oei
Does the effect of one-day simulation team training in obstetric emergencies decline within one year? A post-hoc analysis of a multicentre cluster randomised controlled trial. J van de Ven, AF Fransen, E Schuit, PJ van Runnard Heimel, BW Mol, SG Oei OBJECTIVE: To investigate whether the effect of a one-day simulation-based obstetric team training on patient outcome changes over time. STUDY DESIGN: Post-hoc analysis of a multicentre, open, randomised controlled trial that evaluated team training in obstetrics (TOSTI study)...
July 14, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28721122/hypoxic-training-increases-maximal-oxygen-consumption-in-thoroughbred-horses-well-trained-in-normoxia
#9
Hajime Ohmura, Kazutaka Mukai, Yuji Takahashi, Toshiyuki Takahashi, James H Jones
Hypoxic training is effective for improving athletic performance in humans. It increases maximal oxygen consumption (V̇O2max) more than normoxic training in untrained horses. However, the effects of hypoxic training on well-trained horses are unclear. We measured the effects of hypoxic training on V̇O2max of 5 well-trained horses in which V̇O2max had not increased over 3 consecutive weeks of supramaximal treadmill training in normoxia which was performed twice a week. The horses trained with hypoxia (15% inspired O2) twice a week...
2017: Journal of Equine Science
https://www.readbyqxmd.com/read/28704315/appetite-regulations-after-sprint-exercise-under-hypoxic-condition-in-female-athletes
#10
Chihiro Kojima, Nobukazu Kasai, Aya Ishibashi, Yukako Murakami, Kumiko Ebi, Kazushige Goto
The present study determined changes in appetite-regulating hormones and energy intake after high-intensity interval exercise (HIIT) under hypoxic conditions in trained female athletes. Fifteen female athletes completed three trials on different days of either HIIT under hypoxic conditions (HYP), HIIT under normoxic conditions (NOR), or rest in normoxia (CON). Exercise trials consisted of two successive sets of eight repeated bouts of a 6-s maximal sprint separated by a 30-s rest. Blood samples were obtained to measure plasma acylated ghrelin, glucagon-like peptide-1 (GLP-1), and metabolite concentrations...
July 12, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28686002/cerebrocortical-activity-during-self-paced-exercise-in-temperate-hot-and-hypoxic-conditions
#11
Julien D Périard, Kevin De Pauw, Frank Zanow, Sébastien Racinais
AIM: Heat stress and hypoxia independently influence cerebrocortical activity and impair prolonged exercise performance. This study examined the relationship between electroencephalography (EEG) activity and self-paced exercise performance in control (CON, 18°C, 40% RH), hot (HOT, 35°C, 60%RH) and hypoxic (HYP, 18°C, 40%RH FiO2 : 0.145) conditions. METHODS: Eleven well-trained cyclists completed a 750 kJ cycling time trial in each condition on separate days in a counter-balanced order...
July 7, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28649714/exercise-during-short-term-exposure-to-hypoxia-or-hyperoxia-novel-treatment-strategies-for-type-2-diabetic-patients
#12
REVIEW
C Brinkmann, W Bloch, K Brixius
Both hypoxia (decreased oxygen availability) and hyperoxia (increased oxygen availability) have been shown to alter exercise adaptations in healthy subjects. This review aims to clarify the possible benefits of exercise during short-term exposure to hypoxia or hyperoxia for patients with type 2 diabetes mellitus (T2DM). There is evidence that exercise during short-term exposure to hypoxia can acutely increase skeletal muscle glucose uptake more than exercise in normoxia, and that post-exercise insulin sensitivity in T2DM patients is more increased when exercise is performed under hypoxic conditions...
June 26, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28646182/high-intensity-interval-training-improves-mitochondrial-function-and-suppresses-thrombin-generation-in-platelets-undergoing-hypoxic-stress
#13
Li-Hua Wu, Shao-Chiang Chang, Tieh-Cheng Fu, Ching-Hui Huang, Jong-Shyan Wang
This study elucidates how high-intensity interval training (HIT) and moderate-intensity continuous training (MCT) affect mitochondrial functionality and thrombin generation (TG) in platelets following hypoxic exercise (HE, 100 W under 12% O2 for 30 min). Forty-five healthy sedentary males were randomized to engage either HIT (3-minute intervals at 40% and 80%VO2max, n = 15) or MCT (sustained 60%VO2max, n = 15) for 30 minutes/day, 5 days/week for 6 weeks, or to a control group (CTL, n = 15) that did not received exercise intervention...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28626333/peripheral-circulation-indicators-in-veteran-trail-runners
#14
Alexander Bolotin, Vladislav Bakayev
[Purpose] Competitive sport places strict demands on the cardiovascular systems of veteran trail runners. Our research objective was to evaluate the dynamics of microcirculation parameters of veteran runners in hypoxic and mid-altitude conditions. [Subjects and Methods] Seven male runners from Russia and Italy between the ages of 50 and 60 years were examined whilst competing at mid-altitude (1,500-2,000 m above sea level). The same runners were examined in a simulated mid-altitude hypoxic environment, which was a hypoxic chamber with 16% oxygen concentration, for 720 minutes...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28620311/physiological-adaptations-to-hypoxic-vs-normoxic-training-during-intermittent-living-high
#15
Stefan De Smet, Paul van Herpt, Gommaar D'Hulst, Ruud Van Thienen, Marc Van Leemputte, Peter Hespel
In the setting of "living high," it is unclear whether high-intensity interval training (HIIT) should be performed "low" or "high" to stimulate muscular and performance adaptations. Therefore, 10 physically active males participated in a 5-week "live high-train low or high" program (TR), whilst eight subjects were not engaged in any altitude or training intervention (CON). Five days per week (~15.5 h per day), TR was exposed to normobaric hypoxia simulating progressively increasing altitude of ~2,000-3,250 m...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28597506/skeletal-myofiber-vegf-is-required-for-the-exercise-training-induced-increase-in-dentate-gyrus-neuronal-precursor-cells
#16
Benjamin Rich, Miriam Scadeng, M Yamaguchi, Peter D Wagner, Ellen C Breen
Exercise signals neurogenesis in the dentate gyrus of the hippocampus. This phenomenon requires vascular endothelial growth factor (VEGF) originating from outside the blood brain barrier, but no cellular source has been identified. Thus, we hypothesized that VEGF produced by skeletal myofibers plays a role in regulating hippocampal neuronal precursor cell proliferation following exercise training. This was tested in adult conditional skeletal myofiber-specific VEGF gene-ablated mice (VEGF(HSA-/-) ) by providing VEGF(HSA-/-) and non-ablated (VEGF(f/f) ) littermates with running wheels for 14 days...
June 9, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28589638/inter-observer-reliability-in-reading-amplitude-integrated-electroencephalogram-in-the-newborn-intensive-care-unit
#17
Bhavesh Mehta, Nadine Griffiths, Kaye Spence, Sharon Laing
AIM: Amplitude-integrated electroencephalogram (aEEG) is widely used in neonates to detect electrical seizure and predict outcome following hypoxic ischaemic encephalopathy and other encephalopathy. Because accurate interpretation is important for clinical decision-making and family counselling, inter-observer reliability is a major concern. We aimed to evaluate inter-observer reliability in the interpretation of aEEG tracings in a neonatal intensive care unit. METHODS: Three neonatal intensive care unit clinicians with different levels of experience in reading aEEG independently reviewed and scored aEEG traces using standardised criteria, categories and interpretation rules...
June 7, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28583927/the-effects-of-moderate-intensity-training-in-a-hypoxic-environment-on-transcriptional-responses-in-thoroughbred-horses
#18
Allan J Davie, Li Wen, Andrew R E Cust, Rosalind Beavers, Tom Fyfe, Shi Zhou
This study investigated the effects of six weeks of normobaric hypoxic training on transcriptional expression of the genes associated with mitochondrial and glycolytic activities in Thoroughbred horses. Eight horses were divided into two groups of four. They completed an identical incremental, moderate intensity training program, except that one group trained in a hypoxic chamber with 15% oxygen for 30 min on alternate days except Sundays (HT), while the other group trained in normal air (NC). Prior to and post training, heart rate and blood lactate were measured during an incremental treadmill test...
July 15, 2017: Biology Open
https://www.readbyqxmd.com/read/28580692/using-quality-improvement-to-decrease-birth-asphyxia-rates-after-helping-babies-breathe-training-in-kenya
#19
Amy R L Rule, Esther Maina, David Cheruiyot, Priscilla Mueri, Jeffrey M Simmons, Beena D Kamath-Rayne
AIM: The Helping Babies Breathe (HBB) programme is known to decrease neonatal mortality in low-resource settings but gaps in care still exist. This study describes the use of quality improvement to sustain gains in birth asphyxia-related mortality after HBB. METHODS: Tenwek Hospital, a rural referral hospital in Kenya, identified high rates of birth asphyxia (BA). They developed a goal to decrease the suspected hypoxic-ischaemic encephalopathy (SHIE) rate by 50% within six months after HBB...
June 5, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28575566/-adaptation-to-intermittent-hypoxia-hyperoxia-improves-cognitive-performance-and-exercise-tolerance-in-elderly
#20
U Bayer, O S Glazachev, R Likar, M Burtscher, W Kofler, G Pinter, H Stettner, S Demschar, B Trummer, S Neuwersch
For improvements in exercise tolerance and cognitive function in geriatric patients Multimodal training programs (MTP) are used as combination of physiotherapy, occupational therapy and cardiovascular training. Intermittent Hypoxic-Hyperoxic Training (IHHT), a modified type of intermittent hypoxic training (IHT) is proposed to be included in MTP to elicit more pronounced beneficial effects in exercise tolerance and cognitive functions of geriatric patients likely by an additional pathway than a single MTP. Thirty four patients of the Geriatric Day Clinic aged between 64 and 92 years participated in the placebo controlled clinical trial...
2017: Advances in Gerontology, Uspekhi Gerontologii
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