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https://www.readbyqxmd.com/read/28626333/peripheral-circulation-indicators-in-veteran-trail-runners
#1
Alexander Bolotin, Vladislav Bakayev
[Purpose] Competitive sport places strict demands on the cardiovascular systems of veteran trail runners. Our research objective was to evaluate the dynamics of microcirculation parameters of veteran runners in hypoxic and mid-altitude conditions. [Subjects and Methods] Seven male runners from Russia and Italy between the ages of 50 and 60 years were examined whilst competing at mid-altitude (1,500-2,000 m above sea level). The same runners were examined in a simulated mid-altitude hypoxic environment, which was a hypoxic chamber with 16% oxygen concentration, for 720 minutes...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28620311/physiological-adaptations-to-hypoxic-vs-normoxic-training-during-intermittent-living-high
#2
Stefan De Smet, Paul van Herpt, Gommaar D'Hulst, Ruud Van Thienen, Marc Van Leemputte, Peter Hespel
In the setting of "living high," it is unclear whether high-intensity interval training (HIIT) should be performed "low" or "high" to stimulate muscular and performance adaptations. Therefore, 10 physically active males participated in a 5-week "live high-train low or high" program (TR), whilst eight subjects were not engaged in any altitude or training intervention (CON). Five days per week (~15.5 h per day), TR was exposed to normobaric hypoxia simulating progressively increasing altitude of ~2,000-3,250 m...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28597506/skeletal-myofiber-vegf-is-required-for-the-exercise-training-induced-increase-in-dentate-gyrus-neuronal-precursor-cells
#3
Benjamin Rich, Miriam Scadeng, M Yamaguchi, Peter D Wagner, Ellen C Breen
Exercise signals neurogenesis in the dentate gyrus of the hippocampus. This phenomenon requires vascular endothelial growth factor (VEGF) originating from outside the blood brain barrier, but no cellular source has been identified. Thus, we hypothesized that VEGF produced by skeletal myofibers plays a role in regulating hippocampal neuronal precursor cell proliferation following exercise training. This was tested in adult conditional skeletal myofiber-specific VEGF gene-ablated mice (VEGF(HSA-/-) ) by providing VEGF(HSA-/-) and non-ablated (VEGF(f/f) ) littermates with running wheels for 14 days...
June 9, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28589638/inter-observer-reliability-in-reading-amplitude-integrated-electroencephalogram-in-the-newborn-intensive-care-unit
#4
Bhavesh Mehta, Nadine Griffiths, Kaye Spence, Sharon Laing
AIM: Amplitude-integrated electroencephalogram (aEEG) is widely used in neonates to detect electrical seizure and predict outcome following hypoxic ischaemic encephalopathy and other encephalopathy. Because accurate interpretation is important for clinical decision-making and family counselling, inter-observer reliability is a major concern. We aimed to evaluate inter-observer reliability in the interpretation of aEEG tracings in a neonatal intensive care unit. METHODS: Three neonatal intensive care unit clinicians with different levels of experience in reading aEEG independently reviewed and scored aEEG traces using standardised criteria, categories and interpretation rules...
June 7, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28583927/the-effects-of-moderate-intensity-training-in-a-hypoxic-environment-on-transcriptional-responses-in-thoroughbred-horses
#5
Allan J Davie, Li Wen, Andrew R E Cust, Rosalind Beavers, Tom Fyfe, Shi Zhou
This study investigated the effects of six weeks of normobaric hypoxic training on transcriptional expression of the genes associated with mitochondrial and glycolytic activities in Thoroughbred horses. Eight horses were divided into two groups of four. They completed an identical incremental, moderate intensity training program, except that one group trained in a hypoxic chamber with 15% oxygen for 30 minutes on alternate days except Sundays (HT), while the other group trained in normal air (NC). Prior to and post the training, heart rate and blood lactate were measured during an incremental treadmill test...
June 5, 2017: Biology Open
https://www.readbyqxmd.com/read/28580692/using-quality-improvement-to-decrease-birth-asphyxia-rates-after-helping-babies-breathe-training-in-kenya
#6
Amy R L Rule, Esther Maina, David Cheruiyot, Priscilla Mueri, Jeffrey M Simmons, Beena D Kamath-Rayne
AIM: The Helping Babies Breathe (HBB) program is known to decrease neonatal mortality in low-resource settings but gaps in care still exist. This study describes the use of quality improvement to sustain gains in birth asphyxia-related mortality after HBB. METHODS: Tenwek Hospital, a rural referral hospital in Kenya, identified high rates of birth asphyxia (BA). They developed a goal to decrease the suspected hypoxic ischemic encephalopathy (SHIE) rate by 50% within six months after HBB...
June 5, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28575566/-adaptation-to-intermittent-hypoxia-hyperoxia-improves-cognitive-performance-and-exercise-tolerance-in-elderly
#7
U Bayer, O S Glazachev, R Likar, M Burtscher, W Kofler, G Pinter, H Stettner, S Demschar, B Trummer, S Neuwersch
For improvements in exercise tolerance and cognitive function in geriatric patients Multimodal training programs (MTP) are used as combination of physiotherapy, occupational therapy and cardiovascular training. Intermittent Hypoxic-Hyperoxic Training (IHHT), a modified type of intermittent hypoxic training (IHT) is proposed to be included in MTP to elicit more pronounced beneficial effects in exercise tolerance and cognitive functions of geriatric patients likely by an additional pathway than a single MTP. Thirty four patients of the Geriatric Day Clinic aged between 64 and 92 years participated in the placebo controlled clinical trial...
2017: Advances in Gerontology, Uspekhi Gerontologii
https://www.readbyqxmd.com/read/28565820/beneficial-effects-of-jiawei-shenqi-wan-and-treadmill-training-on-deficits-associated-with-neonatal-hypoxic-ischemia-in-rats
#8
Ha Neui Kim, Malk Eun Pak, Myung Jun Shin, Soo Yeon Kim, Yong Beom Shin, Young Ju Yun, Hwa Kyoung Shin, Byung Tae Choi
Jiawei Shenqi-wan (JSQW), which comprises Shenqi-wan and two additional medicinal herbs, has been widely used for the treatment of various growth impairments, including cerebral palsy. In the present study, JSQW was administered to hypoxic-ischemic Sprague-Dawley rats that underwent treadmill training from 4-7 weeks of age to examine the beneficial effects of combined JSQW and treadmill therapy. Behavioral examinations were performed and a significant improvement in cylinder test performance was observed in rats treated with treadmill training compared with hypoxic-ischemia rats (P<0...
May 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28539142/inspiratory-muscle-training-effects-on-cycling-during-acute-hypoxic-exposure
#9
Mitch Lomax, Heather C Massey, James R House
INTRODUCTION: Hypoxic environments increase the physiological demands of exercise. Inspiratory muscle training can reduce the demands of exhaustive exercise in this environment. This study examined the impact of inspiratory muscle training on moderate intensity hypoxic cycling exercise. METHODS: There were 17 healthy adult men who undertook 4 wk of inspiratory muscle training (N = 8) or 4 wk of sham inspiratory muscle training (N = 9). Subjects completed four fixed intensity (100 W) and duration (10 min) cycle ergometry tests...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28536893/neurologic-recovery-after-cardiac-arrest-a-multifaceted-puzzle-requiring-comprehensive-coordinated-care
#10
REVIEW
Carolina B Maciel, Mary M Barden, David M Greer
Surviving cardiac arrest (CA) requires a longitudinal approach with multiple levels of responsibility, including fostering a culture of action by increasing public awareness and training, optimization of resuscitation measures including frequent updates of guidelines and their timely implementation into practice, and optimization of post-CA care. This clearly goes beyond resuscitation and targeted temperature management. Brain-directed physiologic goals should dictate the post-CA management, as accumulating evidence suggests that the degree of hypoxic brain injury is the main determinant of survival, regardless of the etiology of arrest...
July 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28523996/micro-rnas-exercise-and-cellular-plasticity-in-humans-the-impact-of-dietary-factors-and-hypoxia
#11
Timothée Watier, Anthony Mj Sanchez
Physical exercise is a stress that modulates a plethora of cellular mechanisms to promote morphological and metabolic adaptations. Substantial efforts have been made to better understand the modulation of pathways involved in cell plasticity during exercise, but human explorations may be limited because invasive procedures are often required. In recent years, minimally invasive methods for the analysis of microRNAs (miRNAs) modulation in response to exercise have been developed. miRNAs are small molecules that belong to a family of non-coding RNAs...
May 19, 2017: MicroRNA
https://www.readbyqxmd.com/read/28486858/ante-and-intrapartum-risk-factors-for-neonatal-hypoxic-ischemic-encephalopathy
#12
Cecilia Lundgren, Lars Brudin, Anna-Stina Wanby, Marie Blomberg
PURPOSE: To identify obstetrical risk factors for the diagnosis of neonatal hypoxic ischemic encephalopathy (HIE). A secondary aim was to determine the incidence of HIE. MATERIALS AND METHODS: A retrospective cohort study including 36,086 women with singleton term pregnancies giving live births in Sweden between 2009 and 2013. Cases of HIE were identified from three different sources. Risk factors for HIE were evaluated using univariate and multivariate analyses...
May 9, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28451905/effects-of-altitude-hypoxia-on-single-and-multiple-sprint-performance-a-comprehensive-review
#13
REVIEW
Olivier Girard, Franck Brocherie, Grégoire P Millet
Many sport competitions, typically involving the completion of single- (e.g. track-and-field or track cycling events) and multiple-sprint exercises (e.g. team and racquet sports, cycling races), are staged at terrestrial altitudes ranging from 1000 to 2500 m. Our aim was to comprehensively review the current knowledge on the responses to either acute or chronic altitude exposure relevant to single and multiple sprints. Performance of a single sprint is generally not negatively affected by acute exposure to simulated altitude (i...
April 27, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28445224/impact-of-6-consecutive-days-of-sprint-training-in-hypoxia-on-performance-in-competitive-sprint-runners
#14
Nobukazu Kasai, Sahiro Mizuno, Sayuri Ishimoto, Etsuko Sakamoto, Misato Maruta, Toshiyuki Kurihara, Yuko Kurosawa, Kazushige Goto
The purpose of the present study was to determine the effects of 6 successive days of repeated sprint training in moderate hypoxia on anaerobic capacity in 100-200-m sprint runners. Eighteen male sprint runners (age, 20.0 ± 0.3 years; height, 175.9 ± 1.1 cm; body mass, 65.0 ± 1.2 kg) performed repeated cycling sprints for 6 consecutive days in either normoxic (NOR; fraction of inspired oxygen [FiO2], 20.9%; n = 9) or hypoxic conditions (HYPO; FiO2, 14.5%; n = 9). The repeated sprint ability (10 × 6-s sprints), 30-s maximal sprint ability, maximal oxygen uptake (VO2max), and 60-m running time on the track were measured before and after the training period...
April 18, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28445110/normobaric-hypoxia-increases-the-growth-hormone-response-to-maximal-resistance-exercise-in-trained-men
#15
Dean Filopoulos, Stuart J Cormack, Douglas G Whyte
This study examined the effect of hypoxia on growth hormone (GH) release during an acute bout of high-intensity, low-volume resistance exercise. Using a single-blinded, randomised crossover design, 16 resistance-trained males completed two resistance exercise sessions in normobaric hypoxia (HYP; inspiratory oxygen fraction, (FiO2) 0.12, arterial oxygen saturation (SpO2) 82 ± 2%) and normoxia (NOR; FiO2 0.21, SpO2 98 ± 0%). Each session consisted of five sets of three repetitions of 45° leg press and bench press at 85% of one repetition maximum...
August 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28386234/high-intensity-interval-training-in-normobaric-hypoxia-improves-cardiorespiratory-fitness-in-overweight-chinese-young-women
#16
Zhaowei Kong, Qingde Shi, Jinlei Nie, Tomas K Tong, Lili Song, Longyan Yi, Yang Hu
Previous studies have investigated the effects of high-intensity interval training (HIIT) on cardiorespiratory fitness and body composition in overweight populations. However, the additive effect of HIIT and hypoxia on health parameters is not clear. This study compared the effects of HIIT under hypoxic conditions on cardiometabolic function with that under normoxia in overweight Chinese young women. Methods: A double-blind randomized controlled experimental design was applied. Twenty-four sedentary overweight Chinese young women (weight: 68...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28368957/impact-of-endurance-exercise-in-hypoxia-on-muscle-damage-inflammatory-and-performance-responses
#17
Daichi Sumi, Chihiro Kojima, Kazushige Goto
This study evaluated muscle damage and inflammatory and performance responses following high-intensity endurance exercise in moderate hypoxia among endurance athletes. Nine trained endurance athletes completed two different trials on different days: exercise under moderate hypoxia (H trial, FiO2 = 14.5%) and normoxia (N trial, FiO2 = 20.9%). They performed interval exercises (10 × 3-min running at 95% of VO2max with 60-s of active rest at 60% of VO2max) followed by 30-min of continuous running at 85% of VO2max under either hypoxic or normoxic conditions...
March 25, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28361408/correction-of-abnormalities-provoked-by-long-term-alcoholization-with-hypoxic-hyperoxic-training
#18
T G Sazontova, N V Stryapko, Yu V Arkhipenko
Free radical oxidation in the liver and skeletal muscles as well as stress behavior were examined in rats subjected to a gradual long-term alcoholization with elevated ethanol content from 10 to 40% followed by correction of alcohol-induced disturbances with hypoxic-hyperoxic training. The elevated plus-maze test revealed increased anxiety and appearance of risky behavior in alcoholized rats in the absence of changes in motor and orientation activity. In the liver and skeletal muscles of alcoholized rats, free radical oxidation processes were decompensated despite activation of antioxidant enzymes...
March 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28351441/-oxygen-therapy-not-required-for-all-copd-patients
#19
L E G W Vanfleteren
Long-term oxygen therapy in patients with pronounced hypoxia is an important and life-extending therapy. Many patients have only mild hypoxia, do not experience nocturnal desaturation, or experience desaturation only during exercise. While often applied in clinical practice, the clinical relevance of oxygen therapy was not clear in these patients. A recent randomized controlled trial has now revealed no additional value for long-term oxygen therapy in subjects with mild oxygen desaturation or exercise-induced oxygen desaturation only...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28315193/resistance-training-using-different-hypoxic-training-strategies-a-basis-for-hypertrophy-and-muscle-power-development
#20
REVIEW
Belén Feriche, Amador García-Ramos, Antonio J Morales-Artacho, Paulino Padial
The possible muscular strength, hypertrophy, and muscle power benefits of resistance training under environmental conditions of hypoxia are currently being investigated.Nowadays, resistance training in hypoxia constitutes a promising new training strategy for strength and muscle gains. The main mechanisms responsible for these effects seem to be related to increased metabolite accumulation due to hypoxia. However, no data are reported in the literature to describe and compare the efficacy of the different hypertrophic resistance training strategies in hypoxia...
December 2017: Sports Medicine—Open
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