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https://www.readbyqxmd.com/read/29052745/role-of-fat-and-bone-biomarkers-in-the-relationship-between-ethnicity-and-bone-mineral-density-in-older-men
#1
Grace M F Chan, Tessa Riandini, Sheryl Hui Xian Ng, Su Yen Goh, Chuen Seng Tan, E Shyong Tai, Gustavo Duque, Alvin Choon-Meng Ng, Kavita Venkataraman
Osteoporosis is an important health issue for older adults, and has been relatively understudied in older men. This study aimed to examine ethnic differences in bone mineral density (BMD), and elucidate the role of bone turnover markers (BTMs), fat and fat biomarkers on these ethnic differences. BMD at the lumbar spine and femoral neck, marrow fat at femoral neck, visceral adipose tissue (VAT) and subcutaneous adipose tissue, bone and fat biomarkers were evaluated in 120 healthy men aged ≥ 60 years. Indians had higher BMD values compared to Chinese at the lumbar spine (β = 20...
October 20, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/29049342/association-between-a-mirna-146a-polymorphism-and-susceptibility-to-head-and-neck-squamous-cell-carcinoma-in-chinese-patients-a-meta-analysis-of-8-case-control-studies
#2
Silin Zhang, Fangling Hu, Hongxing Liang, Yuanzhou Liu, Jianqiang Yang, Wensheng Zhou
A closer association has been found between the microRNA-146a rs2910164 polymorphism and the risk of head and neck carcinoma in some molecular epidemiological studies. Recently two meta-analyses were performed to explore the relationship between miRNA-146a polymorphisms and the susceptibility of squamous cell carcinoma of the head and neck (SCCHN); however, they yielded conflicting results in susceptibility regarding ethnic variations. Hence, the present study was performed to explain the relationship between the miRNA-146a rs2910164 polymorphism and the risk of SCCHN development of Chinese patients...
2017: PloS One
https://www.readbyqxmd.com/read/29049201/association-between-folate-intake-and-risk-of-head-and-neck-squamous-cell-carcinoma-an-overall-and-dose-response-prisma-meta-analysis
#3
Chengchao Fan, Siwei Yu, Si Zhang, Xiaojun Ding, Jian Su, Zhigang Cheng
The results of published studies about the relationships between folate intake and risk of head and neck squamous cell carcinoma (HNSCC) remained inconsistent. Hence, a comprehensive and dose-response meta-analysis was performed to clarify the association between folate intake and HNSCC risk.The electric searches of Pubmed, Medline, and EMBASE databases were performed to identify the studies examining the relationship between folate intake and HNSCC risk on April 5, 2017. According to the inclusion criteria, finally 9 studies were included in this meta-analysis...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29043391/analysis-of-the-evolution-of-cortical-and-trabecular-bone-compartments-in-the-proximal-femur-after-spinal-cord-injury-by-3d-dxa
#4
L Gifre, L Humbert, A Muxi, L Del Rio, J Vidal, E Portell, A Monegal, N Guañabens, P Peris
Marked trabecular and cortical bone loss was observed at the proximal femur short-term after spinal cord injury (SCI). 3D-DXA provided measurement of vBMD evolution at both femoral compartments and cortical thinning, thereby suggesting that this technique could be useful for bone analysis in these patients. INTRODUCTION: SCI is associated with a marked increase in bone loss and risk of osteoporosis development short-term after injury. 3D-DXA is a new imaging analysis technique providing 3D analysis of the cortical and trabecular bone from DXA scans...
October 17, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29037111/head-and-neck-size-and-neck-strength-predict-linear-and-rotational-acceleration-during-purposeful-soccer-heading
#5
Jaclyn B Caccese, Thomas A Buckley, Ryan T Tierney, Kristy B Arbogast, William C Rose, Joseph J Glutting, Thomas W Kaminski
There is increasing societal concern about the long-term effects of repeated impacts from soccer heading, but there is little information about ways to reduce head impact severity. The purpose of this study was to identify factors that contribute to head acceleration during soccer heading. One-hundred soccer players completed 12 controlled soccer headers. Peak linear (PLA) and rotational (PRA) accelerations were measured using a triaxial accelerometer and gyroscope. Head acceleration contributing factors were grouped into 3 categories: size (head mass, neck girth), strength (sternocleidomastoid, upper trapezius) and technique [kinematics (trunk, head-to-trunk range-of-motion), sternocleidomastoid and upper trapezius activity]...
October 16, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29031785/prior-mental-disorders-and-subsequent-onset-of-chronic-back-or-neck-pain-findings-from-19-countries
#6
Maria Carmen Viana, Carmen C W Lim, Flavia Garcia Pereira, Sergio Aguilar-Gaxiola, Jordi Alonso, Ronny Bruffaerts, Peter de Jonge, Jose Miguel Caldas-de-Almeida, Siobhan O'Neill, Dan J Stein, Ali Al-Hamzawi, Corina Benjet, Graça Cardoso, Silvia Florescu, Giovanni de Girolamo, Josep Maria Haro, Chiyi Hu, Viviane Kovess-Masfety, Daphna Levinson, Marina Piazza, José Posada-Villa, Daniel Rabczenko, Ronald C Kessler, Kate M Scott
Associations between depression/anxiety and pain are well established, but its directionality is not clear. We examined the associations between temporally prior mental disorders and subsequent self-reported chronic back/neck pain onset, and investigated the variation in the strength of associations by timing of events during the life course, and by gender. Data were from population-based household surveys conducted in 19 countries (n=52,095). Lifetime prevalence and age-of-onset of 16 DSM-IV mental disorders, and the occurrence and age-of-onset of back/neck pain were assessed using the Composite International Diagnostic Interview...
October 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29022686/level-of-education-as-a-risk-factor-for-extensive-prevalence-of-cervical-intervertebral-disc-degenerative-changes-and-chronic-neck-pain
#7
Vedran Markotić, Damir Zubac, Miro Miljko, Goran Šimić, Amra Zalihić, Gojko Bogdan, Dorijan Radančević, Ana Dugandžić Šimić, Josip Mašković
OBJECTIVE: The aim of this study was to document the prevalence of degenerative intervertebral disc changes in the patients who previously reported symptoms of neck pain and to determine the influence of education level on degenerative intervertebral disc changes and subsequent chronic neck pain. METHODS: One hundred and twelve patients were randomly selected from the University Hospital in Mostar, Bosna and Herzegovina, (aged 48.5±12.7 years) and submitted to magnetic resonance imaging (MRI) of the cervical spine...
September 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28991829/sepsis-reduces-bone-strength-before-morphologic-changes-are-identifiable
#8
Zudin A Puthucheary, Yao Sun, Kaiyang Zeng, Lien Hong Vu, Zhi Wei Zhang, Ryan Z L Lim, Nicholas S Y Chew, Matthew E Cove
OBJECTIVES: Survivors of critical illness have an increased prevalence of bone fractures. However, early changes in bone strength, and their relationship to structural changes, have not been described. We aimed to characterize early changes in bone functional properties in critical illness and their relationship to changes in bone structure, using a sepsis rodent model. DESIGN: Experimental study. SETTING: Animal research laboratory. SUBJECTS: Adult Sprague-Dawley rats...
October 6, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28990541/associations-of-dietary-patterns-with-bone-mass-muscle-strength-and-balance-in-a-cohort-of-australian-middle-aged-women
#9
Feitong Wu, Karen Wills, Laura L Laslett, Brian Oldenburg, Graeme Jones, Tania Winzenberg
Influences of dietary patterns on musculoskeletal health are poorly understood in middle-aged women. This cross-sectional analysis from a cohort of 347 women (aged 36-57 years) aimed to examine associations between dietary patterns and musculoskeletal health outcomes in middle-aged women. Diet was measured by the Cancer Council of Victoria FFQ. Total body bone mineral content (TB BMC), femoral neck and lumbar spine bone density (dual-energy X-ray absorptiometry), lower limbs muscle strength (LMS) and balance tests (timed up and go test, step test, functional reach test (FRT) and lateral reach test) were also measured...
October 9, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28975661/high-intensity-resistance-and-impact-training-improves-bone-mineral-density-and-physical-function-in-postmenopausal-women-with-osteopenia-and-osteoporosis-the-liftmor-randomized-controlled-trial
#10
Steven L Watson, Benjamin K Weeks, Lisa J Weis, Amy T Harding, Sean A Horan, Belinda R Beck
Optimal osteogenic mechanical loading requires the application of high-magnitude strains at high rates. High-intensity resistance and impact training (HiRIT) applies such loads but is not traditionally recommended for individuals with osteoporosis because of a perceived high risk of fracture. The purpose of the LIFTMOR trial was to determine the efficacy and to monitor adverse events of HiRIT to reduce parameters of risk for fracture in postmenopausal women with low bone mass. Postmenopausal women with low bone mass (T-score < -1...
October 4, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28975497/exercise-frequency-and-fracture-risk-in-older-adults-how-often-is-enough
#11
REVIEW
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl
PURPOSE OF REVIEW: Due to older people's low sports participation rates, exercise frequency may be the most critical component for designing exercise protocols that address fracture risk. The aims of the present article were to review and summarize the independent effect of exercise frequency (ExFreq) on the main determinants of fracture prevention, i.e., bone strength, fall frequency, and fall impact in older adults. RECENT FINDINGS: Evidence collected last year suggests that there is a critical dose of ExFreq that just affects bone (i...
October 3, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28970518/three-screw-versus-two-screw-fixation-of-distal-fragment-in-fifth-metacarpal-neck-fractures-stabilized-with-locking-plate
#12
Hongyi Zhu, Bingbo Bao, Xianyou Zheng
Fifth metacarpal neck fracture commonly requires open reduction and internal fixation. Locking plate was widely adopted in the treatment of fifth metacarpal neck fracture as first-line choice for fixation. Patients with fifth metacarpal neck fracture receiving locking plate fixation were included for analysis. Features of internal fixation including number of distal and proximal locking screws, diameter of the screws and usage of lag screws were recorded. Clinical and radiographic outcomes included final volar angulation, grip strength, Michigan Hand Outcomes Questionnaire (MHQ) and range of motion (ROM) of fifth metacarpophalangeal joint...
October 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28960489/evaluation-of-radius-microstructure-and-areal-bone-mineral-density-improves-fracture-prediction-in-postmenopausal-women
#13
Emmanuel Biver, Claire Durosier-Izart, Thierry Chevalley, Bert van Rietbergen, René Rizzoli, Serge Ferrari
A majority of low-trauma fractures occurs in subjects with only moderate decrease of areal bone mineral density (aBMD), i.e osteopenia, assessed by dual-energy X-ray absorptiometry (DXA), or low fracture probability assessed by FRAX. We investigated whether peripheral bone microstructure and estimated strength improve the prediction of incident fractures beyond central DXA and FRAX. In this population-based study of 740 postmenopausal women (age 65.0 ± 1.4 years) from the Geneva Retirees Cohort (ISRCTN registry 11865958), we assessed at baseline cortical (Ct) and trabecular (Tb) volumetric bone mineral density (vBMD) and microstructure by peripheral quantitative computed tomography (HR-pQCT), bone strength by micro-finite element analysis, aBMD and trabecular bone score (TBS) by DXA, and FRAX fracture probability...
September 28, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28958658/a-minimum-ten-years-of-follow-up-of-alumina-head-on-delta-liner-total-hip-arthroplasty
#14
Won-Sik Choy, Yong-Han Cha, Chung-Youb Jeon, Kyu-Sang Lee, Ha-Yong Kim
BACKGROUND: In the early days when delta ceramics were developed, there was a period of using delta ceramic liner and alumina ceramic head. Therefore, the purpose of this study is to investigate the clinical and radiological outcomes of total hip arthroplasty using delta ceramic liner on alumina ceramic head after a minimum of 10 years of follow-up and to evaluate problems of early delta ceramic liner. METHODS: Alumina on delta cementless total hip arthroplasty was performed in 92 hips (85 patients) from August 2005 to March 2007 at our hospital...
September 7, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28952870/effects-of-three-infraspinatus-muscle-strengthening-exercises-on-isokinetic-peak-torque-and-muscle-activity
#15
Il-Young Yu, Dong-Kyu Lee, Myoung-Joo Kang, Jaeseop Oh
CONTEXT: The infraspinatus muscle plays a particularly important role in producing primary external rotation (ER) torque and dynamic stability of the shoulder joint. Previous studies have reported that prone external rotation with horizontal abduction (PER), side-lying wiper exercise (SWE), and standing external rotation (STER) were effective exercises for strengthening the infraspinatus. However, we do not have enough knowledge about changes in muscle strength and dynamic muscle activity in each exercise under dynamic conditions...
September 27, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28948267/diffusion-of-single-dye-molecules-in-hydrated-tio2-mesoporous-films
#16
Juan F Angiolini, Martín Stortz, Paula Y Steinberg, Esteban Mocskos, Luciana Bruno, Galo Soler-Illia, Paula C Angelomé, Alejandro Wolosiuk, Valeria Levi
Mesoporous oxide films are attractive frameworks in technological areas such as catalysis, sensing, environmental protection, and photovoltaics. Herein, we used fluorescence correlation spectroscopy to explore how the pore dimensions of hydrated TiO2 mesoporous calcined films modulate the molecular diffusion. Rhodamine B molecules in mesoporous films follow a Fickian process 2-3 orders slower compared to the probe in water. The mobility increases with the pore and neck radii reaching an approximately constant value for a neck radius >2...
October 11, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28933187/headless-screw-fixation-of-metacarpal-neck-fractures-a-mechanical-comparative-analysis
#17
Christopher M Jones, Eric M Padegimas, Nicole Weikert, Samuel Greulich, Asif M Ilyas, Sorin Siegler
BACKGROUND: The purpose of this study was to compare the mechanical properties of metacarpal neck fracture fixation by headless compression screw (HCS) with that of Kirschner wire (KW) cross-pinning and locking plate (LP) fixation. METHODS: A metacarpal neck fracture was created in 30 fourth-generation composite Sawbones metacarpal models. A volar-based wedge was removed using a custom jig to simulate a typical apex dorsal fracture, unstable in flexion. The models were divided into 3 equal groups based on the method of fixation: retrograde cross-pinning with two 1...
September 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28930778/radioprotection-with-amifostine-enhances-bone-strength-and-regeneration-and-bony-union-in-a-rat-model-of-mandibular-distraction-osteogenesis
#18
Catherine N Tchanque-Fossuo, Alexis Donneys, Sagar S Deshpande, Deniz Sarhaddi, Noah S Nelson, Laura A Monson, Sara E Dahle, Steve A Goldstein, Steven R Buchman
BACKGROUND: Using distraction osteogenesis (DO) to regenerate robust endogenous bone could greatly enhance postoncologic reconstruction of head and neck cancer. However, radiation (XRT) corrosive effects still preclude DO's immense potential. We posit that adjunctive pretreatment with the radioprotectant amifostine (AMF) can optimize wound healing and allow for successful DO with quantifiable enhancements in bony union and strength despite previous surgical bed irradiation. METHODS: Two groups of murine left hemimandibles were exposed to a human equivalent radiation dosage fractionated over 5 daily doses of 7 Gy...
September 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28922081/clinical-outcomes-following-conservative-management-of-chronic-traumatic-cervical-myelopathy-a-case-report
#19
Justin Bridges, Roberto Sandoval
BACKGROUND AND PURPOSE: There is limited evidence supporting the conservative management of patients with cervical myelopathy. The purpose of this report is to describe the intervention and outcomes of conservative physical therapy interventions for one patient with chronic cervical myelopathy. CASE DESCRIPTION: This case was a 50-year-old male who sustained a neck injury following a rear-end collision 4 years prior to this therapeutic episode. The patient presented with decreased range of motion in the cervical spine and right upper extremity, strength deficits, altered sensation, poor posture, and reported chronic cervical region pain and difficulty sleeping...
September 18, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28887132/structure-and-diversity-of-human-dendritic-spines-evidenced-by-a-new-three-dimensional-reconstruction-procedure-for-golgi-staining-and-light-microscopy
#20
Roman Reberger, Aline Dall'Oglio, Claudio R Jung, Alberto A Rasia-Filho
BACKGROUND: Different approaches aim to unravel detailed morphological features of neural cells. Dendritic spines are multifunctional units that reflect cellular connectivity, synaptic strength and plasticity. NEW METHOD: A novel three-dimensional (3D) reconstruction procedure is introduced for visualization of dendritic spines from human postmortem brain tissue using brightfield microscopy. The segmentation model was based on thresholding the intensity values of the dendritic spine image along 'z' stacks...
September 5, 2017: Journal of Neuroscience Methods
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