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Tom H van de Belt, Hugo Nijmeijer, David Grim, Lucien Jlpg Engelen, Rinaldo Vreeken, Marleen Mmj van Gelder, Mark Ter Laan
BACKGROUND: Cancer patients need high quality information about the disease stage, treatment options and side effects. High quality information can also improve health literacy, shared decision-making and satisfaction. We created patient-specific 3D models of tumours including surrounding functional areas, and assessed what patients with glioma actually value (or fear) about these models when they are used to educate them about the relation between their tumour and specific brain parts, the surgical procedure, and risks...
June 2, 2018: World Neurosurgery
Alexandra Sideris, Fahad Khan, Alina Boltunova, Germaine Cuff, Christopher Gharibo, Lisa V Doan
Introduction: In 2014, New York (NY) became the 23rd state to legalize medical marijuana (MMJ). The purpose of this survey was to collect data about practicing NY physicians' comfort level, opinions, and experience in recommending or supporting patient use of MMJ. Materials and Methods: An anonymous web-based survey was distributed to medical societies and to academic departments in medical schools within NY. Results: A total of 164 responses were analyzed. Physician participants were primarily located in New York City and surrounding areas...
2018: Cannabis and Cannabinoid Research
Dermot P Maher, Daniel B Carr, Kevin Hill, Brian McGeeney, Valerie Weed, William C Jackson, David J DiBenedetto, Edward M Moriarty, Ronald J Kulich
Objective: This manuscript reviews medical literature published pertaining to the management of chronic pain with medical marijuana therapy (MMJ), with an emphasis on the social, medical, and legal aspects of therapy. Design: Narrative review of peer-reviewed literature. Methods: The 3rd Symposium on Controlled Substances and Their Alternatives for the Treatment of Pain was held in Boston on February 27, 2016, with a focus on MMJ for the treatment of chronic pain...
July 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Brooke K O'Connell, David Gloss, Orrin Devinsky
Treatment-resistant epilepsy (TRE) affects 30% of epilepsy patients and is associated with severe morbidity and increased mortality. Cannabis-based therapies have been used to treat epilepsy for millennia, but only in the last few years have we begun to collect data from adequately powered placebo-controlled, randomized trials (RCTs) with cannabidiol (CBD), a cannabis derivative. Previously, information was limited to case reports, small series, and surveys reporting on the use of CBD and diverse medical marijuana (MMJ) preparations containing: tetrahydrocannabinol (THC), CBD, and many other cannabinoids in differing combinations...
May 2017: Epilepsy & Behavior: E&B
Muza Gondwe
No abstract text is available yet for this article.
September 2016: Malawi Medical Journal: the Journal of Medical Association of Malawi
Chiwoza Bandawe
No abstract text is available yet for this article.
June 2016: Malawi Medical Journal: the Journal of Medical Association of Malawi
Staci A Gruber, Kelly A Sagar, Mary K Dahlgren, Megan T Racine, Rosemary T Smith, Scott E Lukas
Currently, 25 states and Washington DC have enacted full medical marijuana (MMJ) programs while 18 states allow limited access to MMJ products. Limited access states permit low (or zero) tetrahydrocannabinol (THC) and high cannabidiol (CBD) products to treat specified conditions such as uncontrolled epilepsy. Although MMJ products are derived from the same plant species as recreational MJ, they are often selected for their unique cannabinoid constituents and ratios, not typically sought by recreational users, which may impact neurocognitive outcomes...
2016: Frontiers in Pharmacology
Hye-Jin Tak, Tae-Jin Park, Zhenngu Piao, Sang-Hwy Lee
BACKGROUND: Syngnathia is a congenital craniofacial disorder characterized by bony or soft tissue fusion of upper and lower jaws. Previous studies suggested some causative signals, such as Foxc1 or Bmp4, cause the disruption of maxillomandibular identity, but their location and the interactive signals involved remain unexplored. We wanted to examine the embryonic origin of syngnathia based on the assumption that it may be located at the separation between the maxillary and mandibular processes...
January 2017: Developmental Dynamics: An Official Publication of the American Association of Anatomists
Rem Villalobos, M G Yu, R P Berba, Mmj Juan-Bartolome
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
Christiaan Ja van Bergen, Rogier M Gerards, Kim Tm Opdam, Maaike P Terra, Gino Mmj Kerkhoffs
This current concepts review outlines the role of different imaging modalities in the diagnosis, preoperative planning, and follow-up of osteochondral ankle defects. An osteochondral ankle defect involves the articular cartilage and subchondral bone (usually of the talus) and is mostly caused by an ankle supination trauma. Conventional radiographs are useful as an initial imaging tool in the diagnostic process, but have only moderate sensitivity for the detection of osteochondral defects. Computed tomography (CT) and magnetic resonance imaging (MRI) are more accurate imaging modalities...
December 18, 2015: World Journal of Orthopedics
Brian J Fairman
BACKGROUND: Medical marijuana (MMJ) laws and policies have evolved rapidly over the past decade in the United States. Public health concerns over the impact of these laws might be influenced by the degree of MMJ participation, but little is known about changes to this population over time. Trends in registered MMJ participation are described for 13 states in the US and District of Columbia (DC) since 2001. METHODS: Numbers of MMJ participants were obtained from state MMJ patient registries...
February 1, 2016: Drug and Alcohol Dependence
Angelique G H Witteveen, Cheriel J Hofstad, Gino M M J Kerkhoffs
BACKGROUND: The cause of ankle osteoarthritis (OA) is usually trauma. Patients are relatively young, since ankle trauma occurs at a relatively young age. Several conservative treatment options are available, evidence of the benefits and harms of these options are lacking. OBJECTIVES: To assess the benefits and harms of any conservative treatment for ankle OA in adults in order to provide a synthesis of the evidence as a base for future treatment guidelines. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL 2014, issue 9), MEDLINE (Ovid) (1946 up to 11 September 2014), EMBASE (1947 to September 2014), PsycINFO (1806 to September 2014), CINAHL (1985 to September 2014), PEDro (all years till September 2014), AMED until September 2014, ClinicalTrials...
October 17, 2015: Cochrane Database of Systematic Reviews
Mmj Singendonk, B Pullens, Jaa van Heteren, Hhw de Gier, H J Hoeve, A M König-Jung, M P van der Schroeff, Cel Hoekstra, L L Veder, R J van der Pol, M A Benninga, M P van Wijk
BACKGROUND: The Reflux Finding Score for Infants (RFS-I) was developed to objectively assess signs of laryngopharyngeal reflux (LPR). Based on review of flexible laryngoscopic videos, only moderate inter- and highly variable intraobserver reliability was found. We hypothesized that examination of the infant larynx with rigid laryngoscopy would provide better agreement. AIM: to assess the validity of the RFS-I in the detection of LPR-related findings using flexible versus rigid laryngoscopy...
October 2015: Journal of Pediatric Gastroenterology and Nutrition
Nejla Canbulat Şahiner, Sevil İnal, Ayşe Sevim Akbay
PURPOSE: Procedures involving needles are the most common and major sources of pain in children. External cold and vibration via Buzzy (MMJ Labs, Atlanta, GA) is a method that combines cooling and vibration. DESIGN: This study investigated the effect of the combined stimulation of skin with external cold and vibration via Buzzy on the pain and anxiety levels in children during immunization. METHODS: This study was a prospective, randomized controlled trial...
June 2015: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
Peter Aa Struijs, Gino Mmj Kerkhoffs
INTRODUCTION: Injury of the lateral ligament complex of the ankle joint occurs in about one in 10,000 people a day, accounting for a quarter of all sports injuries. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatment strategies for acute ankle ligament ruptures? We searched: Medline, Embase, The Cochrane Library, and other important databases up to November 2009 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review)...
May 13, 2010: Clinical Evidence
Andrea Gauster, Yana Yunusova, David Zajac
The purpose of this study was to assess the effect of speaking rate variation on aerodynamic and acoustic measures of velopharyngeal (VP) function. Twenty-seven healthy adult speakers (14 males, 13 females) participated in the study. The modified pressure-flow method was used to collect aerodynamic data of /m/ and /p/ segments in the word 'hamper' and the utterances 'Mama made some lemon jam' (MMJ) and 'Buy Bobby a puppy' (BBP). SPL was collected simultaneously with aerodynamic data for all utterances. A Nasometer was used to obtain nasalance scores and nasalance distance for MMJ and BBP...
June 2010: Clinical Linguistics & Phonetics
Solomon Jonasi
No abstract text is available yet for this article.
March 2008: Malawi Medical Journal: the Journal of Medical Association of Malawi
Norman E D'hondt, Geert Aufdemkampe, Gino Mmj Kerkhoffs, Peter Aa Struijs, Claire Verheul, C N van Dijk
BACKGROUND: Patellofemoral pain syndrome is a frequently reported condition in active adults. A wide variety of conservative treatment strategies have been described. As yet, no optimal strategy has been identified. Application of orthotic devices e.g. knee braces, knee straps, forms of taping of the knee, active training devices, knee sleeves and inlay soles to support the foot have been advocated to treat this condition. OBJECTIVES: To assess the effectiveness of foot and knee orthotics for treatment of patellofemoral pain syndrome...
January 21, 2009: Cochrane Database of Systematic Reviews
Roderik Metz, Gino Mmj Kerkhoffs, Egbert-Jan Mm Verleisdonk, Geert J van der Heijden
BACKGROUND: We present the design of an open randomized multi-centre study on surgical versus conservative treatment of acute Achilles tendon ruptures. The study is designed to evaluate the effectiveness of conservative treatment in reducing complications when treating acute Achilles tendon rupture. METHODS/DESIGN: At least 72 patients with acute Achilles tendon rupture will be randomized to minimally invasive surgical repair followed by functional rehabilitation using tape bandage or conservative treatment followed by functional rehabilitation with use of a functional bracing system...
2007: BMC Musculoskeletal Disorders
Jie Li, Jun Wang, Jian Zhang, Wei Wang
By using serial mutations, i.e., a residue replaced by 19 kinds of naturally occurring residues, the stability of native conformation and folding behavior of mutated sequences are studied. The 3 x 3 x 3 lattice protein model with two kinds of interaction potentials between the residues, namely the original Miyazawa and Jernigan (MJ) potentials and the modified MJ potentials (MMJ), is used. Effects of various sites in the mutated sequences on the stability and foldability are characterized through the Z-score and the folding time...
April 1, 2004: Journal of Chemical Physics
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