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https://www.readbyqxmd.com/read/27900923/-the-infection-risk-scan-in-clinical-practice-improving-infection-prevention-and-antibiotic-use-through-transparency
#1
I Willemsen, J A J W Kluytmans
OBJECTIVE: The increase in Highly Resistant Micro-Organisms (HRMO) in hospitals and nursing homes requires an intensification of infection prevention measures. This paper describes a new, standardised approach to infection prevention and monitoring of antibiotic use. DESIGN: Cross-sectional, observational study. METHOD: The Infection RIsk Scan (IRIS) measures a number of objectifiable variables in the field of infection prevention, including the dissemination of HRMO, the use of antibiotics and indwelling medical devices, environmental contamination, hand hygiene and personal hygiene of healthcare workers, and various infection control preconditions...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27884325/violet-405-nm-light-a-novel-therapeutic-agent-against-common-pathogenic-bacteria
#2
Mitchell D Barneck, Nathaniel L R Rhodes, Martin de la Presa, James P Allen, Ahrash E Poursaid, Maziar M Nourian, Matthew A Firpo, John T Langell
BACKGROUND: The increasing incidence of healthcare-associated infections (HAIs) and multidrug-resistant organisms demonstrate the need for innovative technological solutions. Staphylococcus aureus, Streptococcus pneumonia, Escherichia coli, and Pseudomonas aeruginosa in particular are common pathogens responsible for a large percentage of indwelling medical device-associated clinical infections. The bactericidal effects of visible light sterilization (VLS) using 405-nm is one potential therapeutic under investigation...
December 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27879557/chryseobacterium-indologenes-associated-pneumonia-in-two-neonates
#3
Shruti Radera, Shalini Tripathi, Jyotsna Agarwal, Mala Kumar
Chryseobacterium species are widely distributed in nature and can rarely cause human infection. Few cases reported in hospitalized patients are in immunocompromised hosts with indwelling devices and associated co-morbidities. Chryseobacterium species are usually multi-drug resistant. We describe two cases of C. indologenes associated-pneumonia in neonates and review the published infant cases.
November 22, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27870871/functional-genomic-analysis-of-candida-albicans-adherence-reveals-a-key-role-for-the-arp2-3-complex-in-cell-wall-remodelling-and-biofilm-formation
#4
Jason A Lee, Nicole Robbins, Jinglin L Xie, Troy Ketela, Leah E Cowen
Fungal biofilms are complex, structured communities that can form on surfaces such as catheters and other indwelling medical devices. Biofilms are of particular concern with Candida albicans, one of the leading opportunistic fungal pathogens of humans. C. albicans biofilms include yeast and filamentous cells that are surrounded by an extracellular matrix, and they are intrinsically resistant to antifungal drugs such that resolving biofilm infections often requires surgery to remove the contaminated device. C...
November 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27849513/venous-thoracic-outlet-syndrome-the-role-of-early-rib-resection
#5
Vienna G Katana, Jeffrey S Weiss
The upper extremity is an uncommon site for deep vein thrombosis and, although most of these thrombotic events are secondary to catheters or indwelling devices, venous thoracic outlet syndrome is an important cause of primary thrombosis. Young, active, otherwise healthy individuals that engage in repetitive upper extremity exercises, such as those required by a military vocation, may be at an increased risk. We present the case of a Naval Officer diagnosed with venous thoracic outlet syndrome whereby a multimodal approach with early surgical decompression was used...
November 2016: Military Medicine
https://www.readbyqxmd.com/read/27821454/sustained-nitric-oxide-releasing-nanoparticles-interfere-with-methicillin-resistant-staphylococcus-aureus-adhesion-and-biofilm-formation-in-a-rat-central-venous-catheter-model
#6
Mircea Radu Mihu, Vitor Cabral, Rodney Pattabhi, Moses T Tar, Kelvin P Davies, Adam J Friedman, Luis R Martinez, Joshua D Nosanchuk
Staphylococcus aureus is frequently isolated in the setting of infections of indwelling medical devices, which are mediated by the microbe's ability to form biofilms on a variety of surfaces. Biofilm-embedded bacteria are more resistant to antimicrobial agents than their planktonic counterparts and often cause chronic infections and sepsis, particularly in patients with prolonged hospitalizations. In this study, we demonstrate that sustained nitric oxide-releasing nanoparticles (NO-np) interfere with S. aureus adhesion and prevent biofilm formation on a rat central venous catheters (CVCs) model of infection...
November 7, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27805758/exploring-relationships-of-catheter-associated-urinary-tract-infection-and-blockage-in-people-with-long-term-indwelling-urinary-catheters
#7
Mary H Wilde, James M McMahon, Hugh F Crean, Judith Brasch
AIMS: The aims were to describe and explore relationships among catheter problems in long-term indwelling urinary catheter users, including excess health care utilization for treating catheter problems. BACKGROUND: Long-term urinary catheter users experience repeated problems with catheter-related urinary tract infection (CAUTI) and blockage of the device, yet little has been reported of the patterns and relationships among relevant catheter variables. DESIGN: Secondary data analysis was conducted from a sample in a randomized clinical trial, using data from the entire sample of 202 persons over 12 months' participation...
November 2, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27778373/urinary-incontinence-but-not-fecal-incontinence-is-a-risk-factor-for-admission-to-aged-residential-care-of-older-persons-in-new-zealand
#8
Philip J Schluter, Charlotte Ward, Edwin P Arnold, Richard Scrase, Hamish A Jamieson
AIMS: To determine if urinary incontinence (UI) and fecal incontinence (FI) were independent risk factors for aged resident care (ARC) admissions for older people, after controlling for confounders and applying apposite statistical methods. METHODS: Since 2012, all community care recipients in New Zealand have undergone a standardized needs assessment using the Home Care International Residential Assessment Instrument (interRAI-HC). The interRAI-HC instrument elicits information on 236 questions over 20 domains, including UI and FI frequency within the last 3 days...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27758704/plant-derived-compounds-as-potential-source-of-novel-anti-biofilm-agents-against-pseudomonas-aeruginosa
#9
Pooi Yin Chung
Pseudomonas aeruginosa is the most common Gram-negative bacterium associated with nosocomial and life-threatening chronic infections in cystic fibrosis patients. This pathogen is well-known for its ability to attach to surfaces of indwelling medical devices to form biofilms, which consist of a regular array of extracellular polymers. Tenaciously bound to the surface of devices and inherently resilient to antibiotic treatment, P. aeruginosa poses a serious threat in clinical medicine and contributes to the persistence of chronic infections...
October 19, 2016: Current Drug Targets
https://www.readbyqxmd.com/read/27752973/tio2-containing-and-zno-containing-borosilicate-glass-a-novel-thin-glass-with-exceptional-antibiofilm-performances-to-prevent-microfouling
#10
Mareike Klinger-Strobel, Oliwia Makarewicz, Mathias W Pletz, Andreas Stallmach, Christian Lautenschläger
Biofilm formation, also known as microfouling, on indwelling medical devices such as catheters or prosthetic joints causes difficult to treat and recurrent infections. It is also the initial step for biocorrosion of surfaces in aquatic environment. An efficient prevention of microfouling is preferable but the development of antibiofilm surfaces is enormously challenging. Therefore, soda-lime, aluminosilicate, and three borosilicate glasses with different TiO2 and ZnO compositions were investigated on their feasibility to prevent biofilm formation by standardized in vitro biofilm assays using different pathogenic bacteria...
December 2016: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/27729907/staphylococcus-epidermidis-biofilm-released-cells-induce-a-prompt-and-more-marked-in-vivo-inflammatory-type-response-than-planktonic-or-biofilm-cells
#11
Angela França, Begoña Pérez-Cabezas, Alexandra Correia, Gerald B Pier, Nuno Cerca, Manuel Vilanova
Staphylococcus epidermidis biofilm formation on indwelling medical devices is frequently associated with the development of chronic infections. Nevertheless, it has been suggested that cells released from these biofilms may induce severe acute infections with bacteraemia as one of its major associated clinical manifestations. However, how biofilm-released cells interact with the host remains unclear. Here, using a murine model of hematogenously disseminated infection, we characterized the interaction of cells released from S...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27729510/commensal-protection-of-staphylococcus-aureus-against-antimicrobials-by-candida-albicans-biofilm-matrix
#12
Eric F Kong, Christina Tsui, Sona Kucharíková, David Andes, Patrick Van Dijck, Mary Ann Jabra-Rizk
: Biofilm-associated polymicrobial infections, particularly those involving fungi and bacteria, are responsible for significant morbidity and mortality and tend to be challenging to treat. Candida albicans and Staphylococcus aureus specifically are considered leading opportunistic fungal and bacterial pathogens, respectively, mainly due to their ability to form biofilms on catheters and indwelling medical devices. However, the impact of mixed-species biofilm growth on therapy remains largely understudied...
October 11, 2016: MBio
https://www.readbyqxmd.com/read/27717603/burden-spectrum-and-impact-of-healthcare-associated-infection-at-a-south-african-children-s-hospital
#13
A Dramowski, A Whitelaw, M F Cotton
BACKGROUND: In most African countries the prevalence and effects of paediatric healthcare-associated infection (HCAI) and human immunodeficiency virus (HIV) infection are unknown. AIM: To investigate the burden, spectrum, risk factors, and impact of paediatric HCAI by prospective clinical surveillance at a South African referral hospital. METHODS: Continuous prospective clinical and laboratory HCAI surveillance using Centers for Disease Control and Prevention (CDC)/National Healthcare Safety Network (NHSN) definitions was conducted at Tygerberg Children's Hospital, South Africa, from May 1(st) to October 31(st) in 2014 and 2015...
December 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27695218/hickman-to-central-venous-catheter-a-case-of-difficult-venous-access-in-a-child-suffering-from-acute-lymphoblastic-leukemia
#14
Arunangshu Chakraborty, Sanjit Agrawal, Taniya Datta, Suparna Mitra, Rakhi Khemka
Chemotherapy in children suffering from cancer usually requires placement of an indwelling central venous catheter (CVC). A child may need to undergo repeated procedures because of infection and occlusion of previous access devices. We present a case of CVC insertion in a child suffering from acute lymphoblastic leukemia where an innovative technique was employed.
October 2016: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/27684464/device-life-of-the-tracheoesophageal-voice-prosthesis-revisited
#15
Jan S Lewin, Leah M Baumgart, Martha P Barrow, Katherine A Hutcheson
Importance: Voice prosthesis (VP) device life is a limiting factor of tracheoesophageal (TE) voice restoration that drives patient satisfaction, health care costs, and overall burden. Historic data suggest that TE VPs have an average device life of generally 3 to 6 months, but these data are typically derived from small samples using only 1 or 2 devices. Objective: To reexamine current device life in a large, contemporary cancer hospital in the United States that uses a wide assortment of VPs...
September 29, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27683632/hemodynamic-monitoring-in-heart-failure-and-pulmonary-hypertension-from-analog-tracings-to-the-digital-age
#16
REVIEW
Ryan Davey, Amresh Raina
Hemodynamic monitoring has long formed the cornerstone of heart failure (HF) and pulmonary hypertension diagnosis and management. We review the long history of invasive hemodynamic monitors initially using pulmonary artery (PA) pressure catheters in the hospital setting, to evaluating the utility of a number of implantable devices that can allow for ambulatory determination of intracardiac pressures. Although the use of indwelling PA catheters has fallen out of favor in a number of settings, implantable devices have afforded clinicians an opportunity for objective determination of a patient's volume status and pulmonary pressures...
September 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/27672214/diluted-honey-inhibits-biofilm-formation-potential-application-in-urinary-catheter-management
#17
Somadina Emineke, Alan J Cooper, Sarah Fouch, Brian R Birch, Bashir A Lwaleed
AIMS: Biofilms are ubiquitous and when mature have a complex structure of microcolonies in an extracellular polysaccharide and extracellular DNA matrix. Indwelling medical devices harbour biofilms which have been shown to cause infections and act as reservoirs for pathogens. Urinary catheters are often in place for considerable periods of time and are susceptible to both encrustation and biofilm formation. Strategies for minimising biofilm occurrence underpin an active research area in biomedicine...
September 26, 2016: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27634359/phytochemicals-as-effective-quorum-quenchers-against-bacterial-communication
#18
Subramaniyan S, Divyasree S, Sandhia G S
BACKGROUND: Quorum sensing or the bacterial information flow in an orchestrated manner is an essential feature of many pathogenic bacteria. Quorum quenching molecules (QQ) can inhibit the growth of such bacteria. OBJECTIVE: The purpose of this study is to evaluate the potential of plant extracts as quorum quenchers and monitor the recent patents. METHODS: Many available reports and patents are on synthetic ligand molecules or even compounds isolated from cyanobacteria (Honaucin A) and other microorganisms inhibiting quorum sensing molecules...
September 8, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27627125/results-after-implementation-of-a-protocol-on-the-incidence-of-urinary-tract-infection-in-an-intensive-care-unit
#19
Anna Letícia Miranda, Ana Lúcia Lyrio de Oliveira, Daiana Terra Nacer, Cynthia Adalgisa Mesojedovas Aguiar
OBJECTIVE: to compare the results of urinary tract infection incidence, by means of the rate of indwelling urethral catheter use, and to identify microorganisms in urine cultures and surveillance cultures before and after the implementation of a clinical protocol for intensive care unit patients . METHOD: urinary tract infection is defined as a positive urine culture > 105 CFU/mL, notified by the hospital infection control service, six months before and after the implementation of the protocol...
September 9, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27621932/a-survey-of-adherence-to-guidelines-to-prevent-healthcare-associated-infections-in-iranian-intensive-care-units
#20
Mahmood Shamshiri, Boudouin Fuh Suh, Nooredin Mohammadi, Reza Nabi Amjad
BACKGROUND: Healthcare-associated infections (HAIs) are acquired by patients while receiving care. The highest incidence of HAIs has been documented in admissions to intensive care units. Adherence to evidence-based practices is the most important step for preventing HAIs. OBJECTIVES: To determine the rate of adherence to evidence-based post-insertion recommended care practices after admission into the intensive care unit for the following devices: central line catheter, indwelling urinary catheter, and mechanical ventilator...
June 2016: Iranian Red Crescent Medical Journal
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