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Indwelling devices

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https://www.readbyqxmd.com/read/29336750/percutaneous-versus-cut-down-technique-for-indwelling-port-placement
#1
Mario Matiotti-Neto, Mariam F Eskander, Omidreza Tabatabaie, Gyulnara Kasumova, Lindsay A Bliss, Sing Chau Ng, Nicholas E Tawa, Blanche Murphy, Jonathan F Critchlow, Jennifer F Tseng
The superiority of surgical cut-down of the cephalic vein versus percutaneous catheterization of the subclavian vein for the insertion of totally implantable venous access devices (TIVADs) is debated. To compare the safety and efficacy of surgical cut-down versus percutaneous placement of TIVADs. This is a single-institution retrospective cohort study of oncologic patients who had TIVADs implanted by 14 surgeons. Primary outcomes were inability to place TIVAD by the primary approach and postoperative complications within 30 days...
December 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29324429/a-pilot-clinical-study-of-a-safe-and-efficient-stool-management-system-in-patients-with-fecal-incontinence
#2
Ashlee Garcia, Sally Fung, Karen Lou Kennedy-Evans
INTRODUCTION: According to the Wound Ostomy Continence Nursing Society's Continence Committee, the incidence of fecal incontinence (FI) can occur from 18% to 37% in an acute care setting. A stool management system has been designed to manage FI in bedridden patients and has proven to be efficacious in wound management and prevention and infection control, provide safer patient outcomes, and enhance ease of nursing. OBJECTIVE: This study aims to evaluate the safety and efficacy of an intrarectal device intended to manage fecal incontinence in hospitalized bedridden patients through nonclinical and clinical testings...
December 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29301288/use-of-pleuroperitoneal-shunt-in-chylothorax-related-to-central-line-associated-thrombosis-in-sickle-cell-disease
#3
Elizabeth Spiwak, Chad Wiesenauer, Arun Panigrahi, Ashok Raj
Central vein thrombosis as a cause of chylothorax is uncommon, and in a few cases in the literature was related to thrombotic complications of central venous access devices (CVAD). Superior vena cava (SVC) occlusion-induced chylothorax has been described in adult sickle cell disease (SCD) in a setting of chronic indwelling CVAD. There are limited reports on chylothorax induced by central venous thrombosis secondary to chronic CVAD in children with SCD. We describe an 8-year-old male patient, with a history of SCD, maintained on long term erythrocytapheresis for primary prevention of stroke, and whose clinical course was complicated by chylothorax which was successfully treated with a pleuroperitoneal shunt...
January 2, 2018: Children
https://www.readbyqxmd.com/read/29287710/rifampin-resistance-in-staphylococcus-epidermidis-molecular-characterization-and-fitness-cost-of-rpob-mutations
#4
Yu Mi Wi, Kerryl E Greenwood-Quaintance, Cassandra L Brinkman, Jean Y H Lee, Benjamin P Howden, Robin Patel
Molecular mechanisms and characteristics of rifampin resistance in Staphylococcus epidermidis are poorly characterized, even though S. epidermidis is one of the most common nosocomial pathogens associated with indwelling medical device-related infections. The aim of this study was to investigate the evolution of rifampin resistance and to characterize the associated molecular mechanisms in S. epidermidis. Rifampin-resistant mutants from two rifampin-susceptible S. epidermidis strains, RP62A and IDRL-8883, were selected through in vitro and in vivo exposure to rifampin...
December 26, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29250229/leadless-pacemakers-implant-explant-and-long-term-safety-and-efficacy-data
#5
REVIEW
Krishna Kancharla, Abhishek J Deshmukh, Paul A Friedman
Implantable cardiac pacemakers have seen remarkable progress in the last sixty years and remained as cornerstone therapy for symptomatic bradycardia. Despite this progress the current day traditional transvenous implanted pacemaker systems are limited by the need for a surgically created pocket for the generator, indwelling leads in the vascular system and lastly passage through the tricuspid valve. A majority of the implant and explant related complications are due to the surgical pocket and indwelling leads...
August 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29227579/obesity-type-2-diabetes-increases-inflammation-periosteal-reactive-bone-formation-and-osteolysis-during-staphylococcus-aureus-implant-associated-bone-infection
#6
Christopher W Farnsworth, Eric M Schott, Abigail M Benvie, Jacob Zukoski, Stephen L Kates, Edward M Schwarz, Steven R Gill, Michael J Zuscik, Robert A Mooney
Obese and type 2 diabetic (T2D) patients have a 5-fold increased rate of infection following placement of an indwelling orthopaedic device. Though implant infections are associated with inflammation, periosteal reactive bone formation and osteolysis, the effect of obesity/T2D on these complicating factors has not been studied. To address this question, C57BL/6J mice were fed a high fat diet (60% Kcal from fat) to induce obesity/T2D, or a control diet (10% Kcal from fat) for three months, and challenged with a transtibial pin coated with a bioluminescent USA300 strain of S...
December 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29199894/local-and-systemic-effects-of-a-silver-nitrate-coated-indwelling-pleural-catheter-in-an-animal-model-of-pleurodesis
#7
Alain Tremblay, Christine T Kearney, Chris Hanks, Jennifer Hughes Hanks, David S White, Marcia E Pereira, Craig E Zook, Karen Sargis, Luke Zhang
Purpose/Aim of the study: This study assessed the safety and potential toxicity of a silver nitrate coated indwelling pleural catheter (SNCIPC) designed to create pleurodesis in a large animal model. MATERIALS AND METHODS: Sixteen animals underwent insertion of either a SNCIPC or an uncoated silicone catheter. Half of the animals were sacrificed at day 7 and the others at day 30. Animal weight and assessment of well-being, pleural fluid and blood collection were performed at regular intervals...
November 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/29191009/prediction-of-broad-spectrum-pathogen-attachment-to-coating-materials-for-biomedical-devices
#8
Paulius Mikulskis, Andrew L Hook, Adam Dundas, Derek J Irvine, Olutoba Sanni, Daniel G Anderson, Robert Langer, Morgan Russell Alexander, Paul Williams, David A Winkler
Bacterial infections in healthcare settings are a frequent accompaniment to both routine procedures such as catheterization and surgical site interventions. Their impact is becoming even more marked as the numbers of medical devices that are used to manage chronic health conditions and improve quality of life increases. The resistance of pathogens to multiple antibiotics is also increasing, adding an additional layer of complexity to the problems of employing safe and effective medical procedures. One approach to reducing the rate of infections associated with implanted and indwelling medical devices is the use of polymers that resist the formation of bacterial biofilms...
December 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29130513/falls-and-hip-fractures-associated-with-urinary-incontinence-among-older-men-and-women-with-complex-needs-a-national-population-study
#9
Philip J Schluter, Edwin P Arnold, Hamish A Jamieson
AIMS: To determine if urinary incontinence (UI) was an independent risk factor for falls and hip fractures in community-dwelling older men and women with complex needs, after controlling for confounders. METHODS: Since 2012, all community care recipients in New Zealand have undergone standardized needs assessments using the Home Care International Residential Assessment Instrument (interRAI-HC). The interRAI-HC elicits information over multiple domains, including UI frequency and falls...
November 11, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29129031/evaluation-and-management-of-staphylococcus-aureus-bacteriuria-an-updated-review
#10
REVIEW
Stamatis Karakonstantis, Dimitra Kalemaki
BACKGROUND AND AIMS: There is little guidance regarding the evaluation and management of patients with Staphylococcus aureus bacteriuria (SABU). Here, we aimed to provide an up-to-date review of the literature. METHODS: We searched PubMed, Scopus, and clinical trial registries for articles evaluating the epidemiology of SABU, risk factors of SABU, the association of SABU with urinary tract infection, bacteremia and invasive S. aureus infections, and the management of patients with SABU...
November 11, 2017: Infection
https://www.readbyqxmd.com/read/29127346/microelectrode-implantation-in-motor-cortex-causes-fine-motor-deficit-implications-on-potential-considerations-to-brain-computer-interfacing-and-human-augmentation
#11
Monika Goss-Varley, Keith R Dona, Justin A McMahon, Andrew J Shoffstall, Evon S Ereifej, Sydney C Lindner, Jeffrey R Capadona
Intracortical microelectrodes have shown great success in enabling locked-in patients to interact with computers, robotic limbs, and their own electrically driven limbs. The recent advances have inspired world-wide enthusiasm resulting in billions of dollars invested in federal and industrial sponsorships to understanding the brain for rehabilitative applications. Additionally, private philanthropists have also demonstrated excitement in the field by investing in the use of brain interfacing technologies as a means to human augmentation...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29117532/structure-mechanics-and-instability-of-fibrin-clot-infected-with-staphylococcus-epidermidis
#12
Tianhui Maria Ma, J Scott VanEpps, Michael J Solomon
Health care-associated infection, over half of which can be attributed to indwelling medical devices, is a strong risk factor for thromboembolism. Although most experimental models of medical device infection draw upon isolated bacterial biofilms, in fact there is no infection without host protein contribution. Here we study, to our knowledge, a new model for medical device infection-that of an infected fibrin clot-and show that the common blood-borne pathogen Staphylococcus epidermidis influences this in vitro model of a blood clot mechanically and structurally on both microscopic and macroscopic scales...
November 7, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/29117074/context-for-practice-hyperbaric-oxygen-therapy-pouching-techniques-for-neonates-wait-time-for-patients-with-soiled-pads-and-pressure-injury-prevention-with-use-of-indwelling-rectal-devices
#13
https://www.readbyqxmd.com/read/29109700/exploring-the-genome-and-phenotype-of-multi-drug-resistant-klebsiella-pneumoniae-of-clinical-origin
#14
João Anes, Daniel Hurley, Marta Martins, Séamus Fanning
Klebsiella pneumoniae is an important nosocomial pathogen with an extraordinary resistant phenotype due to a combination of acquired resistant-elements and efflux mechanisms. In this study a detailed molecular characterization of 11 K. pneumoniae isolates of clinical origin was carried out. Eleven clinical isolates were tested for their susceptibilities, by disk diffusion and broth microdilution and interpreted according to CLSI guidelines. Efflux activity was determined by measuring the extrusion of ethidium bromide and biofilm formation was assessed following static growth in Müeller-Hinton and minimal media M9 broths at two temperatures and time points...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29079154/breaking-the-chain-of-infection-in-older-adults-a-review-of-risk-factors-and-strategies-for-preventing-device-related-infections
#15
REVIEW
Gregory Schrank, Westyn Branch-Elliman
Device-related infections (DRIs) are a significant cause of morbidity and mortality among older adults. Indwelling devices (urinary catheters, percutaneous feeding tubes, and central venous catheters) are frequently used in this vulnerable population. Indwelling devices provide a portal of entry for pathogenic organisms to invade a susceptible host and cause infection and are an important target for infection prevention and antimicrobial stewardship efforts. Within the "Chain of Infection" that leads to DRIs in older adults, multiple opportunities exist to implement interventions that "break the links" and reduce colonization with multidrug-resistant organisms, reduce infections, and improve antimicrobial use...
December 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29072041/epidemiology-of-serratia-marcescens-infections-in-nicu-of-a-teaching-and-research-hospital-in-northern-italy
#16
Elisa Buttinelli, Ilaria Ardoino, Giulia Domeniconi, Monica Lanzoni, Lorenza Pugni, Andrea Ronchi, Fabio Mosca, Elia Biganzoli, Silvana Castaldi
BACKGROUND: Serratia marcescens (Sm) is a known cause of infection and colonization in neonates receiving intensive care. The aim of this study was to identify the risk factors for colonization and infection with Sm in Neonatal Intensive Care Unit (NICU) of a tertiary care Hospital. METHODS: A casecontrol study was conducted from January to December 2011 in neonates admitted to the NICU. Cases are patients with a microbiologically confirmed infection or colonization, controls were randomly chosen among patients admitted to the same NICU...
October 25, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/29060539/a-swallowable-sensing-device-platform-with-wireless-power-feeding-and-chemical-reaction-actuator
#17
Ryota Nakamura, Shintaro Izumi, Hiroshi Kawaguchi, Hidetoshi Ohta, Masahiko Yoshimoto
This paper presents a swallowable sensor device that can be ingested orally, later passing to the stomach, where the device can indwell for long periods. Using wireless communication, it can be egested at any time after it is triggered. This device can indwell using a silicone balloon in the gastrointestinal tract. A chemical reaction inflates the balloon inside the stomach. Then it is deflated to egest the sensor device using an actuator with electrolysis of water. Energy for the actuator with electrolysis can be fed wirelessly...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29050604/chitosan-as-an-effective-inhibitor-of-multidrug-resistant-acinetobacter-baumannii
#18
E M Costa, S Silva, S Vicente, M Veiga, F Tavaria, M M Pintado
Over the last two decades worldwide levels of antibiotic resistance have risen leading to the appearance of multidrug resistant microorganisms. Acinetobacter baumannii is a known skin pathogen which has emerged as a major cause of nosocomial outbreaks due to its capacity to colonize indwelling medical devices and natural antibiotic resistance. With chitosan being an effective antimicrobial agent against antibiotic resistant microorganisms, the aim of this work was to access its potential as an alternative to traditional antimicrobials in the management of A...
December 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28988900/biofilm-forming-capacity-of-blood-borne-candida-albicans-strains-and-effects-of-antifungal-agents
#19
Hanni Turan, Müge Demirbilek
Infections related to Candida albicans biofilms and subsequent antifungal resistance have become more common with the increased use of indwelling medical devices. Regimens for preventing fungal biofilm formation are needed, particularly in high-risk patients. In this study, we investigated the biofilm formation rate of multiple strains of Candida albicans (n=162 clinical isolates), their antifungal susceptibility patterns, and the efficacy of certain antifungals for preventing biofilm formation. Biofilm formation was graded using a modified Christensen's 96-well plate method...
October 5, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28952963/amorphous-silicon-carbide-ultramicroelectrode-arrays-for-neural-stimulation-and-recording
#20
Felix Deku, Yarden Cohen, Alexandra Joshi-Imre, Aswini Kanneganti, Timothy Gardner, Stuart Cogan
OBJECTIVE: Foreign body response to indwelling cortical microelectrodes limits the reliability of neural stimulation and recording, particularly for extended chronic applications in behaving animals. The extent to which this response compromises the chronic stability of neural devices depends on many factors including the materials used in the electrode construction, the size, and geometry of the indwelling structure. Here, we report on the development of microelectrode arrays (MEAs) based on amorphous silicon carbide (a-SiC)...
September 27, 2017: Journal of Neural Engineering
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