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https://www.readbyqxmd.com/read/28296770/evaluation-of-intrathecal-drug-delivery-system-for-intractable-pain-in-advanced-malignancies-a-prospective-cohort-study
#1
Shuyue Zheng, Liangliang He, Xiaohui Yang, Xiuhua Li, Zhanmin Yang
Pain is prevalent in advanced malignancies; however, some patients cannot get adequate pain relief by conservative routes of analgesic administration or experience serious side effects related to high dose of opioids. For those who have exhausted multimodal conservative analgesic, intrathecal drug delivery is an alternative intervention for truly effective pain management. The objective of this study was to evaluate the clinical efficacy and safety of intrathecal drug delivery system (IDDS) for the treatment of intractable pain in advanced cancer patients...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28271587/strategies-for-reduction-in-the-duration-of-intravenous-drug-use-interest-of-drug-tracers-as-quality-indicators-to-improve-intravenous-to-oral-switch
#2
Jennifer Corny, Simon Perreau, Anne-Pauline Thivilliers, Céline Leplay, Delphine Chevalier, Hélène Beaussier, Yvonnick Bézie
RATIONALE, AIMS, AND OBJECTIVES: Intravenous (IV) to oral (PO) drug switch is a challenge for tertiary care institutions for several reasons: catheter-related infections, patient's pain and discomfort or higher costs, and overuse of IV drugs considered as an irrational use of medicines. The objective was to evaluate yearly acetaminophen and proton-pump inhibiters' (PPIs) IV/PO ratios from 2011 to 2015 and to determine their correlation with all drugs IV/PO ratios and their relevance as drug tracers...
March 7, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28224103/management-of-parenteral-nutrition-in-critically-ill-patients
#3
REVIEW
Paolo Cotogni
Artificial nutrition (AN) is necessary to meet the nutritional requirements of critically ill patients at nutrition risk because undernutrition determines a poorer prognosis in these patients. There is debate over which route of delivery of AN provides better outcomes and lesser complications. This review describes the management of parenteral nutrition (PN) in critically ill patients. The first aim is to discuss what should be done in order that the PN is safe. The second aim is to dispel "myths" about PN-related complications and show how prevention and monitoring are able to reach the goal of "near zero" PN complications...
February 4, 2017: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28165582/-extended-subcutaneous-route-technique-a-quick-subcutaneous-tunnelling-technique-for-picc-insertion
#4
Stefano Elli, Chiara Abbruzzese, Luigi Cannizzo, Simona Vimercati, Stefania Vanini, Alberto Lucchini
PURPOSE: To describe a quick tunnelling technique for peripherally inserted central catheter (PICC) insertion called the "extended subcutaneous route" technique. METHODS: The "extended subcutaneous route" technique is described step by step. RESULTS: In 18 consecutive PICCs, inserted with extended route technique in ASST Monza, no complications during insertion were registered. In 969 catheter days observed, we identified only one accidental dislodgement...
January 25, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28017547/a-systematic-review-of-waterborne-infections-from-nontuberculous-mycobacteria-in-health-care-facility-water-systems
#5
Trudy Li, Lydia S Abebe, Ryan Cronk, Jamie Bartram
Healthcare-acquired infections are an increasing problem for health care providers and policy makers. Water is an overlooked source of infectious microorganisms in health care facilities. Waterborne nontuberculous mycobacteria (NTM) are ubiquitous, and particularly problematic in health care facility water systems, and cause a variety of diseases. The purpose of this review is to assess health care associated NTM infections from health care facility water systems. We documented susceptible populations, modes of transmission, and the median attack rate (e...
December 19, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27869426/an-umbilical-venous-catheter-complication-presented-as-acute-abdomen-case-report
#6
Mustafa O Oztan, Ozkan Ilhan, Elif Abay, Gokhan Koyluoglu
Umbilical venous catheterization has become a widely accepted intravenous route for premature babies. These catheters allow administration of parenteral nutrition and medication and facilitate blood sampling. Besides these benefits, they also have significant potential complications like portal vein thrombosis, infection, vascular or hepatic injury, arrhythmia and sepsis. One of the rare but important complication is extravasation of the fluids due to misplacement of the catheter. The typical symptoms of this condition are sudden deterioration, hepatic enlargement, hematocrit drop, hypotension and abdominal distension...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27807156/subcutaneous-infusion-of-fluids-for-hydration-or-nutrition-a-review
#7
REVIEW
Riccardo Caccialanza, Thierry Constans, Paolo Cotogni, Gary P Zaloga, Alessandro Pontes-Arruda
Subcutaneous infusion, or hypodermoclysis, is a technique whereby fluids are infused into the subcutaneous space via small-gauge needles that are typically inserted into the thighs, abdomen, back, or arms. In this review, we provide an overview of the technique, summarize findings from studies that have examined the use of subcutaneous infusion of fluids for hydration or nutrition, and describe the indications, advantages, and disadvantages of subcutaneous infusion. Taken together, the available evidence suggests that, when indicated, subcutaneous infusion can be effective for administering fluids for hydration or nutrition, with minimal complications, and has similar effectiveness and safety to the intravenous route...
November 2, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27743808/arteriovenous-fistula-combined-with-brachial-artery-superficialization-is-effective-in-patients-with-a-high-risk-of-maturation-failure
#8
Masaaki Murakami, Genichi Sakaguchi, Noriko Mori
OBJECTIVE: In patients with a high risk of fistula immaturity, we created arteriovenous fistulas (AVFs) combined with brachial artery superficialization. With this procedure, the superficialized arteries are used as drawing routes and the AVFs as returning routes. This is a technical report about AVFs combined with brachial artery superficialization. METHODS: Twenty-four consecutive patients with a high risk of fistula immaturity who underwent AVFs with brachial artery superficialization were included in this single-center retrospective study...
February 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27709274/-injuries-to-blood-vessels-near-the-heart-caused-by-central-venous-catheters
#9
J Abram, J Klocker, N Innerhofer-Pompernigg, M Mittermayr, M C Freund, N Gravenstein, V Wenzel
Injuries to blood vessels near the heart can quickly become life-threatening and include arterial injuries during central venous puncture, which can lead to hemorrhagic shock. We report 6 patients in whom injury to the subclavian artery and vein led to life-threatening complications. Central venous catheters are associated with a multitude of risks, such as venous thrombosis, air embolism, systemic or local infections, paresthesia, hemothorax, pneumothorax, and cervical hematoma, which are not always immediately discernible...
November 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/27601303/safety-and-functionality-of-transhepatic-hemodialysis-catheters-in-chronic-hemodialysis-patients
#10
Bekir Şanal, Ömer Fatih Nas, Nurullah Doğan, Mehmet Korkmaz, Kadir Hacıkurt, Abdulmecid Yıldız, İrem İris Kan Aytaç, Bahattin Hakyemez, Cüneyt Erdoğan
PURPOSE: We aimed to investigate the safety and functionality of tunneled transhepatic hemodialysis catheters in chronic hemodialysis patients. METHODS: Thirty-eight patients (20 women aged 56±10 years and 18 men aged 61±11 years) with transhepatic tunneled hemodialysis catheters were evaluated. The date of the first transhepatic catheterization, indications, procedure details, functional time periods of catheters, reasons for the removal or revision of catheters, catheter-related complications, and current conditions of patients were retrospectively analyzed...
November 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/27527505/prophylactic-treatment-of-chronic-renal-disease-in-patients-undergoing-peritoneal-dialysis-and-colonized-by-staphylococcus-aureus-a-systematic-review-and-meta-analysis
#11
Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso, Dulce Barbosa
BACKGROUND: This study was performed to evaluate the clinical effectiveness of alternative strategies for the prevention and treatment of patients with chronic kidney disease undergoing peritoneal dialysis and colonized by Staphylococcus aureus. METHODS: A systematic review and meta-analysis were performed. The literature search involved the following databases: the Cochrane Controlled Trials Register, Embase, LILACS, CINAHL, SciELO, and PubMed/Medline. The descriptors were "Staphylococcus aureus," "MRSA," "MSSA," "treatment," "decolonization," "nasal carrier," "colonization," "chronic kidney disease," "dialysis," and "peritoneal dialysis...
2016: BMC Nephrology
https://www.readbyqxmd.com/read/27445617/continuous-thoracic-sympathetic-ganglion-block-in-complex-regional-pain-syndrome-patients-with-spinal-cord-stimulation-implantation
#12
EungDon Kim, MiSun Roh, SooHyang Kim, DaeHyun Jo
The sympathetic block is widely used for treating neuropathic pain such as complex regional pain syndrome (CRPS). However, single sympathetic block often provides only short-term effect. Moreover, frequent procedures for sympathetic block may increase the risk of complications. The use of epidural route may be limited by concern of infection in case of previous implantation of the spinal cord stimulation (SCS). In contrast, a continuous sympathetic block can be administered without such concerns. The continuous thoracic sympathetic block (TSGB) has been used to treat the ischemic disease and other neuropathic conditions such as postherpetic neuralgia...
2016: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/27411385/multiple-adaptive-routes-of-salmonella-enterica-typhimurium-to-biocide-and-antibiotic-exposure
#13
Tânia Curiao, Emmanuela Marchi, Denis Grandgirard, Ricardo León-Sampedro, Carlo Viti, Stephen L Leib, Fernando Baquero, Marco R Oggioni, José Luis Martinez, Teresa M Coque
BACKGROUND: Biocides and antibiotics are used to eradicate or prevent the growth of microbial species on surfaces (occasionally on catheters), or infected sites, either in combination or sequentially, raising concerns about the development of co-resistance to both antimicrobial types. The effect of such compounds on Salmonella enterica, a major food-borne and zoonotic pathogen, has been analysed in different studies, but only few works evaluated its biological cost, and the overall effects at the genomic and transcriptomic levels associated with diverse phenotypes resulting from biocide exposure, which was the aim of this work...
2016: BMC Genomics
https://www.readbyqxmd.com/read/27319367/predictors-of-early-postoperative-voiding-dysfunction-and%C3%A2-other-complications-following-a-midurethral-sling
#14
Christopher M Ripperda, Joseph T Kowalski, Zaid Q Chaudhry, Aman S Mahal, Jennifer Lanzer, Nabila Noor, Meadow M Good, Linda S Hynan, Peter C Jeppson, David D Rahn
BACKGROUND: The rates reported for postoperative urinary retention following midurethral sling procedures are highly variable. Determining which patients have a higher likelihood of failing a voiding trial will help with preoperative counseling prior to a midurethral sling. OBJECTIVE: The objective of the study was to identify preoperative predictors for failed voiding trial following an isolated midurethral sling. STUDY DESIGN: A retrospective, multicenter, case-control study was performed by including all isolated midurethral sling procedures performed between Jan...
November 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27207611/ultrasound-guided-placement-of-the-distal-catheter-in-paediatric-ventriculoatrial-shunts-an-appraisal-of-efficacy-and-complications
#15
David J Clark, Aabir Chakraborty, Derek J Roebuck, Dominic N P Thompson
PURPOSE: Ventriculoatrial (VA) shunts are commonly used as a second-line treatment of hydrocephalus when the peritoneum is an unsuitable site for the distal catheter. Many centres now utilise ultrasound and interventional radiology techniques to aid placement of the distal catheter. The purpose of this study was to conduct a contemporary audit of VA shunting in children using interventional radiology techniques for placement of the distal catheter. METHODS: A retrospective analysis of all patients who had VA shunts inserted between June 2000 and June 2010 was conducted using a prospectively updated surgical database and case notes review...
July 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27106643/image-guided-transvesicular-drainage-of-pelvic-fluid-collections-a-safe-and-effective-alternative-approach
#16
Raj R Ayyagari, Cliff Yeh, Melih Arici, Hamid Mojibian, Eric Reiner, Jeffrey S Pollak
To evaluate the safety and efficacy of percutaneous transvesicular drainage of pathologic pelvic fluid collections, a series of 15 patients who underwent 16 transvesicular drainage catheter placements was retrospectively reviewed. All patients had collections suspicious for infection that were posterior to the bladder or superior to the bladder behind loops of bowel, and were otherwise inaccessible. All 15 collections were percutaneously accessed via the bladder with standard drainage catheters. All collections resolved completely with no complications...
May 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/26980633/chest-pain-due-to-pinch-off-syndrome-radiological-findings-and-endovascular-rescue
#17
E Viviani, A M Giribono, D Ferrara, A Santagata, D Narese, F Midiri, D Albano, M Porcellini
Port-a-cath is widely used as a route for administration of drugs in hematology and oncology patients and, recently, has been adapted also for hemodialysis patients. Major complications include infection, thrombosis, arrhythmia, and embolization. The Pinch-off-syndrome (POS) means the clavicle and the first rib compress the long-term central venous catheter. The reported incidence rate ranges from 1.4% to 4.1%. This syndrome can be recognized on chest radiography by observing a thinning of the catheter lumen through the passage between the clavicle and the first rib...
2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/26896945/fluoroscopically-guided-tunneled-trans-caudal-epidural-catheter-technique-for-opioid-free-neonatal-epidural-analgesia
#18
Andrew D Franklin, Elisabeth M Hughes
Epidural analgesia confers significant perioperative advantages to neonates undergoing surgical procedures but may be very technically challenging to place using a standard interlaminar loss-of-resistance to saline technique given the shallow depth of the epidural space. Thoracic epidural catheters placed via the caudal route may reduce the risk of direct neural injury from needle placement, but often pose higher risks of infection and/or improper positioning if placed without radiographic guidance. We present a detailed method of placing a fluoroscopically guided, tunneled transcaudal epidural catheter, which may reduce both of these risks...
2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/26853855/glutamine-for-induction-of-remission-in-crohn-s-disease
#19
REVIEW
Anthony K Akobeng, Mamoun Elawad, Morris Gordon
BACKGROUND: Crohn's disease is a chronic relapsing condition of the alimentary tract with a high morbidity secondary to bowel inflammation. Glutamine plays a key role in maintaining the integrity of the intestinal mucosa and has been shown to reduce inflammation and disease activity in experimental models of Crohn's disease. OBJECTIVES: To evaluate the efficacy and safety of glutamine supplementation for induction of remission in Crohn's disease. SEARCH METHODS: We searched the following databases from inception to November 15, 2015: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, and the Cochrane IBD Group Specialised Register...
February 8, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26838725/preclinical-efficacy-of-clumping-factor-a-in-prevention-of-staphylococcus-aureus-infection
#20
Xue Li, Xiaogang Wang, Christopher D Thompson, Saeyoung Park, Wan Beom Park, Jean C Lee
UNLABELLED: Treatment of Staphylococcus aureus infections has become increasingly difficult because of the emergence of multidrug-resistant isolates. Development of a vaccine to prevent staphylococcal infections remains a priority. To determine whether clumping factor A (ClfA) is a good target protein for inclusion in a multivalent vaccine, we evaluated its efficacy in a variety of relevant staphylococcal infection models, challenging with different S. aureus strains. ClfA adsorbed to Alhydrogel and mixed with Sigma Adjuvant System was more immunogenic and stimulated a more robust Th17 response than ClfA administered with alum alone...
February 2, 2016: MBio
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