keyword
MENU ▼
Read by QxMD icon Read
search

forensic test

keyword
https://www.readbyqxmd.com/read/29778046/evaluation-of-the-microhaplotypes-panel-for-dna-mixture-analyses
#1
Peng Chen, Caiyong Yin, Zheng Li, Yan Pu, Youjia Yu, Peng Zhao, Dexin Chen, Weibo Liang, Lin Zhang, Feng Chen
The identification of a suspect in a DNA mixture typed with the standard short tandem repeat polymorphism (STR) kits has faced challenges. Several improved methods or technologies have been introduced to address this issue. However, some complex situations in the process remain elusive. In the present study, we presented a panel of 26 tiny microhaplotypes, each generating a relatively high (>3.0) effective number of alleles (Ae ) and possessing low (<50 bp) sequence lengths. The average Ae and heterozygosity values among the 9 populations of 26 microhaps were in ranges from 2...
May 12, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29778045/massively-parallel-sequencing-of-124-snps-included-in-the-precision-id-identity-panel-in-three-east-asian-minority-ethnicities
#2
Jing Liu, Zheng Wang, Guanglin He, Xueying Zhao, Mengge Wang, Tao Luo, Chengtao Li, Yiping Hou
Massively parallel sequencing (MPS) technologies can sequence many targeted regions of multiple samples simultaneously and are gaining great interest in the forensic community. The Precision ID Identity Panel contains 90 autosomal SNPs and 34 upper Y-Clade SNPs, which was designed with small amplicons and optimized for forensic degraded or challenging samples. Here, 184 unrelated individuals from three East Asian minority ethnicities (Tibetan, Uygur and Hui) were analyzed using the Precision ID Identity Panel and the Ion PGM System...
May 15, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29777982/documentation-and-analysis-of-traumatic-injuries-in-clinical-forensic-medicine-involving-structured-light-three-dimensional-surface-scanning-versus-photography
#3
Awatif Shamata, Tim Thompson
Non-contact three-dimensional (3D) surface scanning has been applied in forensic medicine and has been shown to mitigate shortcoming of traditional documentation methods. The aim of this paper is to assess the efficiency of structured light 3D surface scanning in recording traumatic injuries of live cases in clinical forensic medicine. The work was conducted in Medico-Legal Centre in Benghazi, Libya. A structured light 3D surface scanner and ordinary digital camera with close-up lens were used to record the injuries and to have 3D and two-dimensional (2D) documents of the same traumas...
May 10, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29777949/evaluation-of-skin-or-sweat-characteristic-mrnas-for-inferring-the-human-origin-of-touched-contact-traces
#4
Tomoko Akutsu, Ken Watanabe, Ayari Takamura, Koichi Sakurada
The source of small amounts of touch DNA, which is transferred from the skin to an object when it is handled or touched, could be an issue in the forensic analysis of criminal cases. Here, we performed an extended evaluation of skin- or sweat-characteristic mRNAs to investigate their usability to infer whether an object has been handled or touched by someone. First, we compared the expression levels of candidate genes between skin swabs and other body fluids by quantitative RT-PCR analysis. Among the analyzed genes, corneodesmosin (CDSN), late cornified envelope 1C (LCE1C), filaggrin (FLG), desmocollin 1, and dermcidin were selected for further analysis on the basis of their specificities and sensitivities...
May 14, 2018: Legal Medicine
https://www.readbyqxmd.com/read/29777425/the-use-of-hiv-post-exposure-prophylaxis-in-forensic-medicine-following-incidents-of-sexual-violence-in-hamburg-germany-a-retrospective-study
#5
Julia Ebert, Jan Peter Sperhake, Olaf Degen, Ann Sophie Schröder
In Hamburg, Germany, the initiation of HIV post-exposure prophylaxis (HIV PEP) in cases of sexual violence is often carried out by forensic medical specialists (FMS) using the city's unique Hamburg Model. FMS-provided three-day HIV PEP starter packs include a combination of raltegravir and emtricitabine/tenofovir. This study aimed to investigate the practice of offering HIV PEP, reasons for discontinuing treatment, patient compliance, and whether or not potential perpetrators were tested for HIV. We conducted a retrospective study of forensic clinical examinations carried out by the Hamburg Department of Legal Medicine following incidents of sexual violence from 2009 to 2016...
May 18, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29775922/acid-phosphatase-test-on-phadebas-%C3%A2-sheets-an-optimized-method-for-presumptive-saliva-and-semen-detection
#6
Yael Herman, Ilan Feine, Ron Gafny
The precise and efficient detection of semen and saliva in sexual assault case-work items is a critical step in the forensic pipeline. The outcome of this stage may have a profound impact on identifying perpetrators as well as on the investigation process and the final outcome in court. Semen detection is usually based on the activity of acid phosphatase (AP), an enzyme found in high concentration in the seminal plasma. Amylase, an enzyme catalyzing starch hydrolysis is found in high concentrations in saliva and therefore is a useful target for its detection...
April 30, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29775918/determining-gender-by-taking-measurements-from-magnetic-resonance-images-of-the-patella
#7
Hacer Yasar Teke, Özge Ünlütürk, Elif Günaydin, Semra Duran, Sait Özsoy
BACKGROUND: A key step in making a positive identification in forensic medicine is the establishment of a biological profile, which involves determining factors such as gender, age, ancestry, and stature. The goal of this study was to determine if gender could be established by taking various measurements of the patella taken from magnetic resonance imaging (MRI) images and analyzing the variations by gender. METHODS: The sample group consisted of 220 patients (110 male and 110 female) whose patella were measured using MRI images of their left knee...
May 8, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29775859/facilitating-complex-dna-mixture-interpretation-by-sequencing-highly-polymorphic-haplotypes
#8
Lev Voskoboinik, Uzi Motro, Ariel Darvasi
Interpretation of complex DNA mixtures is an ongoing challenge in the field of forensic genetics. Commonly used STR markers are quite polymorphic, enabling very high statistical association between a single source DNA profile from a crime scene and a matching suspect. STR typing of low order mixtures with two and three contributors also commonly produces high statistical association for a contributor, using current interpretation software. However higher order mixtures, with four contributors or more, are more challenging...
May 2, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29769487/length-of-vermiform-appendix-in-bangladeshi-people-of-different-age-and-sex
#9
S A Sumi, M Khalil, S Mannan, S Chowdhury, M K Khan, U K Paul, U K Zaman, S F Karim, A Rahman, M M Rahman, A Kabir, S Farjan, M T Alam, E Z Epsi, N S Nitu, N J Khan, L Jabeen, S Tabriz
A cross sectional descriptive study was performed on 70 postmortem vermiform appendix (male 34 and female 36) to find out the length of vermiform appendix of Bangladeshi people in different age and sex. The specimens were collected from autopsy laboratory of the Department of Forensic Medicine, Mymensingh Medical College, Mymensingh, Bangladesh from October 2016 to March 2017 by purposive sampling technique. The collected samples were divided into four age groups. They were Group A (upto 20 years), Group B (21 to 40 years), Group C (41 to 60 years) and Group D (above 60 years)...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29768653/n-ethyl-pentylone-related-deaths-in-alabama
#10
Daniel Atherton, Daniel Dye, C Andrew Robinson, Rachel Beck
n-Ethyl pentylone (NEP) is a chemical substance derived from cathinone. Synthetic cathinones are an evolving group of drugs with stimulating, mind-altering effects sometimes referred to as novel or new psychoactive substances (NPS). There is scarce information in the medical literature regarding forensic cases in which NEP is detected in toxicological testing. We present four fatalities involving NEP from Alabama in 2017. Deaths were attributed to NEP toxicity in two cases (peripheral blood concentrations of 0...
May 16, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29764734/can-the-contralateral-limb-be-used-as-a-control-during-the-growing-period-in-a-rodent-model
#11
Tanvir Mustafy, Irène Londono, Isabelle Villemure
The contralateral limb is often used as a control in various clinical, forensic and anthropological studies. However, no studies have been performed to determine if the contra-lateral limb is a suitable control during the bone development period. The aim of this study was to determine the bilateral symmetry of growing rat tibiae in terms of geometric shape, mechanical strength and bone morphological parameters with developmental stages. Left and right tibias of 18 male Sprague-Dawley rats at 4, 8 and 12 weeks of age were scanned with micro-CT for bone-morphometric evaluation and for 3D deviation analysis to quantify the geometric shape variations between left and right tibiae...
May 12, 2018: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29762744/forensically-relevant-blow-flies-in-lebanon-survey-and-identification-using-molecular-markers-diptera-calliphoridae
#12
Salman Shayya, Régis Debruyne, André Nel, Dany Azar
Calliphoridae are among the first insects associated to decomposing animal remains. We have collected 1,841 specimens of three calliphorid genera: Calliphora, Lucilia, and Chrysomya, from different Lebanese localities as a first step in implementing a database of insects of forensic relevance for the country. Blow-flies are crucial for the estimation of the postmortem interval. DNA-based identification is a rapid and accurate method, often used for morphologically similar species, especially for immatures or incomplete specimens...
May 12, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29754257/fatal-unexpected-death-due-to-familial-hemophagocytic-lymphohistiocytosis-type-3
#13
Jiao Mu, Chunting Jin, Zhenglian Chen, Jianfeng Li, Bin Lv, Hongmei Dong
Familial hemophagocytic lymphohistiocytosis is a rare autosomal recessive disorder of immune dysregulation associated with uncontrolled activation of cytotoxic T cells and macrophages. Herein, we report a case of a 14-month-old Chinese boy who presented with fever, abdominal distension and thrombopenia, and died within 3 days of admission to the hospital. Postmortem examination revealed pleuroperitoneal fluid, enlarged mesenteric lymph nodes and hepatosplenomegaly. Histopathological examination showed interstitial pneumonia, hepatonecrosis and hemophagocytosis...
May 12, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29753936/matrixmetalloproteinases-and-tissue-inhibitors-of-metalloproteinases-immunhistochemical-markers-in-the-diagnosis-of-lethal-myocardial-infarctions
#14
Felix Mayer, Martin Falk, Ragnar Huhn, Friederike Behmenburg, Stefanie Ritz-Timme
Matrixmetalloproteinases (MMP) 2 and 9 as well as tissue inhibitor of metalloproteinases (TIMP) 1 were tested as markers of myocardial early ischemia/infarctions. Experiments with an animal model, the isolated Langendorff heart, and analysis of human tissue samples drawn during autopsies were performed. Results of the experiments with the Langendorff model implied that the detectable amount of the markers might increase early after the onset of ischemia, in less than one hour, under ideal conditions. The results of the examined human cases showed that MMP-2 is constantly detectable in human myocardial tissue with an increased amount in case of an infarction with longer survival times...
April 27, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29753263/the-hirisplex-s-system-for-eye-hair-and-skin-colour-prediction-from-dna-introduction-and-forensic-developmental-validation
#15
Lakshmi Chaitanya, Krystal Breslin, Sofia Zuñiga, Laura Wirken, Ewelina Pośpiech, Magdalena Kukla-Bartoszek, Titia Sijen, Peter de Knijff, Fan Liu, Wojciech Branicki, Manfred Kayser, Susan Walsh
Forensic DNA Phenotyping (FDP), i.e. the prediction of human externally visible traits from DNA, has become a fast growing subfield within forensic genetics due to the intelligence information it can provide from DNA traces. FDP outcomes can help focus police investigations in search of unknown perpetrators, who are generally unidentifiable with standard DNA profiling. Therefore, we previously developed and forensically validated the IrisPlex DNA test system for eye colour prediction and the HIrisPlex system for combined eye and hair colour prediction from DNA traces...
April 12, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29752198/age-estimation-of-hispanic-children-using-the-london-atlas
#16
David McCloe, Ian Marion, Marcio A da Fonseca, Michael Colvard, Sakher AlQahtani
PURPOSE: To test the accuracy of the London Atlas for age estimation of Hispanic children and to determine if there is any difference in age accuracy between Hispanic males and females. METHODS: The London Atlas was used to estimate age from panoramic radiographs of 17 males and 17 females for each year of age from six to 15.99 years, using the electronic patient database of a dental school. Exclusion criteria included gross pathology, hypodontia, hyperdontia, and previous orthodontic treatment...
April 16, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29745330/metabolism-of-synthetic-cannabinoids-encountered-in-clinical-casework-major-in-vivo-metabolites-of-jwh-007-jwh-019-jwh-203-jwh-307-ur-144-xlr-11-am-2201-mam-2201-and-am-694-in-human-urine-using-lc-ms-ms
#17
Volker Auwarter, Melanie Hutter, S Broecker, Stefan Kneisel, Floria Franz, Simon D Brandt
BACKGROUND: `Herbal mixtures` containing synthetic cannabinoid receptor agonists (SCRAs) are promoted as legal alternative to marihuana and are easily available via the Internet. Keeping analytical methods for the detection of these SCRAs up-to-date is a continuous challenge for clinicians and toxicologists due to the high diversity of the chemical structures and the frequent emergence of new compounds. Since many SCRAs are extensively metabolized, analytical methods used for urine testing require previous identification of the major metabolites of each compound...
May 9, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29744586/a-systematic-review-and-meta-analysis-of-the-fully-formed-wisdom-tooth-as-a-radiological-marker-of-adulthood
#18
Mattias Haglund, Håkan Mörnstad
Assessment of third molar development on dental radiograms is one of the most commonly used methods of forensic age estimation. Despite widespread use and numerous studies, there is a paucity of aggregated data on how well a fully mature third molar identifies adulthood (> 18 years), the most important threshold in a medicolegal context. Therefore, a systematic review and meta-analysis was conducted. A total of 1229 studies were screened, and 82 studies were assessed for inclusion. Twenty-four studies, with a pooled cohort of 19,690 individuals, presented true positive (TP), true negative (TN), false positive (FP), and false negative (FN) outcomes, enabling meta-analysis...
May 10, 2018: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29743506/self-reference-and-random-sampling-approach-for-label-free-identification-of-dna-composition-using-plasmonic-nanomaterials
#19
Lindsay M Freeman, Lin Pang, Yeshaiahu Fainman
The analysis of DNA has led to revolutionary advancements in the fields of medical diagnostics, genomics, prenatal screening, and forensic science, with the global DNA testing market expected to reach revenues of USD 10.04 billion per year by 2020. However, the current methods for DNA analysis remain dependent on the necessity for fluorophores or conjugated proteins, leading to high costs associated with consumable materials and manual labor. Here, we demonstrate a potential label-free DNA composition detection method using surface-enhanced Raman spectroscopy (SERS) in which we identify the composition of cytosine and adenine within single strands of DNA...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29743333/pinocchio-testing-in-the-forensic-analysis-of-waiting-lists-using-public-waiting-list-data-from-finland-and-spain-for-testing-newcomb-benford-s-law
#20
Jaime Pinilla, Beatriz G López-Valcárcel, Christian González-Martel, Salvador Peiro
OBJECTIVE: Newcomb-Benford's Law (NBL) proposes a regular distribution for first digits, second digits and digit combinations applicable to many different naturally occurring sources of data. Testing deviations from NBL is used in many datasets as a screening tool for identifying data trustworthiness problems. This study aims to compare public available waiting lists (WL) data from Finland and Spain for testing NBL as an instrument to flag up potential manipulation in WLs. DESIGN: Analysis of the frequency of Finnish and Spanish WLs first digits to determine if their distribution is similar to the pattern documented by NBL...
May 9, 2018: BMJ Open
keyword
keyword
35715
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"