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https://www.readbyqxmd.com/read/29906811/comparison-of-hand-sewn-versus-coupled-venous-anastomoses-in-traumatic-lower-extremity-reconstruction
#1
John T Stranix, William J Rifkin, Z-Hye Lee, Lavinia Anzai, Adam Jacoby, Daniel J Ceradini, Vishal Thanik, Pierre B Saadeh, Jamie P Levine
BACKGROUND:  Microvascular reconstruction of the lower extremity has the highest reported complication and flap failure rates of any anatomical region. Despite widespread adoption of the mechanical anastomotic venous coupler and encouraging results in other anatomical regions, there are limited reports examining its use in the lower extremity. This study compares outcomes between coupled and hand-sewn venous anastomoses in traumatic lower extremity reconstruction. METHODS:  Retrospective review of our institutional flap registry from 1979 to 2016 identified soft tissue free flaps performed for the reconstruction of Gustilo type IIIB/IIIC open tibial fractures...
June 15, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29906753/a-feasibility-study-on-biological-nitrogen-removal-bnr-via-integrated-thiosulfate-driven-denitratation-with-anammox
#2
Jin Qian, Mingkuan Zhang, Yaoguo Wu, Juntao Niu, Xing Chang, Hairui Yao, Sihai Hu, Xiangjun Pei
To exploit the advantages of less electron donor consumptions in partial-denitrification (denitratation, NO3 - → NO2 - ) as well as less sludge production in autotrophic denitrification (AD) and anammox, a novel biological nitrogen removal (BNR) process through combined anammox and thiosulfate-driven denitratation was proposed here. In this study, the ratio of S2 O3 2- -S/NO3 - -N and pH are confirmed to be two key factors affecting the thiosulfate-driven denitratation activity and nitrite accumulation. Simultaneous high denitratation activity and substantial nitrite accumulation were observed at initial S2 O3 2- -S/NO3 - -N ratio of 1...
June 12, 2018: Chemosphere
https://www.readbyqxmd.com/read/29906740/diagnostic-challenges-in-clinical-radiological-and-histopathological-tests-regarding-papillomatous-lesions-of-the-breast
#3
Birgitte Bruun Rasmussen, Eva Balslev, Ib Jarle Christensen, Charlotte Lanng, Anne Bak, Hanne Galatius, Maj-Lis Møller Talman, Nahid Sharghi Someh, Ilse Vejborg, Mette Okholm
Papillomas of the female breast is a relatively frequent lesion, and the majority are benign when excised. However, some may host malignant or premalignant areas. Consequently, it is a worldwide accepted principle to excise the lesion whenever diagnosed. However, this leads to a large number of patients having an unnecessary operation. The present study was designed to investigate whether we could find clinical, radiological and pathological factors in the preoperative, diagnostic setting that could identify patients hosting a benign papilloma in order to avoid operation...
May 22, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29906706/clinical-utility-of-emse-and-stess-in-predicting-hospital-mortality-for-status-epilepticus
#4
Yu Zhang, Deng Chen, Da Xu, Ge Tan, Ling Liu
PURPOSE: To explore the applicability of the epidemiology-based mortality score in status epilepticus (EMSE) and the status epilepticus severity score (STESS) in predicting hospital mortality in patients with status epilepticus (SE) in western China. Furthermore, we sought to compare the abilities of the two scales to predict mortality from convulsive status epilepticus (CSE) and non-convulsive status epilepticus (NCSE). METHOD: Patients with epilepsy (n = 253) were recruited from the West China Hospital of Sichuan University from January 2012 to January 2016...
May 25, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29906680/an-updated-assessment-of-morbidity-and-mortality-following-skull-base-surgical-approaches
#5
Brittany N Burton, Jenny Q Hu, Aria Jafari, Richard D Urman, Ian F Dunn, W Linda Bi, Adam S DeConde, Rodney A Gabriel
OBJECTIVES: Updated multi-institutional database studies assessing perioperative risk factors on 30-day morbidity and mortality after skull base surgeries are limited. We aim to identify perioperative risk factors and report the incidence of 30-day morbidity and mortality in adult patients after skull base surgery. PATIENTS AND METHODS: We queried the 2007-2016 American College of Surgeons National Surgical Quality Improvement program database to identify patients who underwent anterior, middle, or posterior skull base surgery...
June 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29906679/multivariate-analytics-of-chromatographic-data-visual-computing-based-on-moving-window-factor-models
#6
Valentin Steinwandter, Michal Šišmiš, Patrick Sagmeister, Ulrich Bodenhofer, Christoph Herwig
Chromatography is one of the most versatile unit operations in the biotechnological industry. Regulatory initiatives like Process Analytical Technology and Quality by Design led to the implementation of new chromatographic devices. Those represent an almost inexhaustible source of data. However, the analysis of large datasets is complicated, and significant amounts of information stay hidden in big data. Here we present a new, top-down approach for the systematic analysis of chromatographic datasets. It is the goal of this approach to analyze the dataset as a whole, starting with the most important, global information...
June 5, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29906674/use-of-trace-elements-addition-for-anaerobic-digestion-of-brewer-s-spent-grains
#7
Claire Bougrier, Delphine Dognin, Cécile Laroche, Jesús Andrés Cacho Rivero
The brewery industry generates a large amount of by-products and notably Brewer's Spent Grain (BSG) which seems an attractive substrate for anaerobic digestion. Nevertheless, previous studies have shown risk of inhibition in the mono-digestion of lignocellulosic substrates. One way to stabilize the reaction is the addition of trace elements. The current study evaluates and compares the stability of BSG anaerobic mono-digestion with and without addition of trace elements for several BSG samples. Based on the average composition of the BSG, two levels of nutrients addition were defined and tested on 4 different BSG samples...
June 12, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29906644/retroperitoneal-versus-open-intraperitoneal-necrosectomy-in-step-up-therapy-for-infected-necrotizing-pancreatitis-a-meta-analysis
#8
REVIEW
Yun-Bing Wang, Xiao-Li Yang, Long Chen, Zheng-Ju Chen, Chun-Mu Miao, Jin Xia
BACKGROUND: Step-up therapy is the recommended therapy for infected necrotizing pancreatitis (INP). However, the most appropriate secondary therapy for use after initial drainage has not been fully determined. This meta-analysis was designed to evaluate the efficacy and safety of retroperitoneal versus open intraperitoneal necrosectomy as part of a step-up strategy for INP. MATERIALS AND METHODS: Eight online databases were searched for randomized controlled trials (RCTs) and cohorts comparing retroperitoneal and open intraperitoneal step-up approaches for treating INP...
June 12, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29906630/a-rare-occurrence-of-viability-of-both-small-and-large-bowel-in-ileosigmoid-knotting-a-case-report
#9
Simbarashe Gift Mungazi, Brightson Mutseyekwa, Mordecai Sachikonye
INTRODUCTION: Ileosigmoid knot is an uncommon cause of acute intestinal obstruction where the ileum wraps around the base of a redundant sigmoid colon. CASE PRESENTATION: We present an unusual case of a 45-year-old male patient who presented with signs and symptoms of intestinal obstruction. Exploratory laparotomy revealed an ileosigmoid knot. Both the small and large bowels were viable. The sigmoid colon was resected an end to end anastomosis was done. His post-operative period was uneventful...
June 8, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29906618/treatment-outcomes-of-17-patients-with-atypical-spinal-meningioma-including-4-with-metastases-a-retrospective-observational-study
#10
Sung Hyun Noh, Kyung Hyun Kim, Dong Ah Shin, Jeong Yoon Park, Seong Yi, Sung Uk Kuh, Keung Nyun Kim, Dong Kyu Chin, Keun Su Kim, Do Heum Yoon, Yong Eun Cho
BACKGROUND CONTEXT: Because of the scarcity of atypical spinal meningioma, there is a lack of research on this type of tumor or its associated metastases. PURPOSE: The aim of this study was to investigate the biological behavior of atypical spinal meningioma and identify its prognostic factors by reviewing surgical and clinical outcomes of patients with these tumors. STUDY DESIGN/SETTING: A retrospective chart review was performed. PATIENT SAMPLE: We retrospectively reviewed the data from all patients who underwent spinal cord tumor excision between 1994 and 2017...
June 12, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29906617/the-effect-of-psychosocial-measures-of-resilience-and-self-efficacy-in-patients-with-neck-and-lower-back-pain
#11
Shaan A Ahmed, Govind Shantharam, Adam E M Eltorai, Davis A Hartnett, Avi Goodman, Alan H Daniels
BACKGROUND CONTEXT: Psychosocial risk factors may predispose to progression of back and neck pain to chronic pain or disability. Resilience (the ability to recover from stress) and pain self-efficacy (confidence that one can perform daily activities despite pain) are important psychometric properties shown to affect health and illness. PURPOSE: To examine the relationships among resilience, pain self-efficacy, and disability in spine patients. STUDY DESIGN/SETTING: Prospective, single-center orthopedic spine clinic...
June 12, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29906614/assessing-risk-and-related-complications-after-reversal-of-combat-associated-ostomies
#12
Luke R Johnston, Matthew J Bradley, Carlos J Rodriguez, Michael P McNally, Eric A Elster, James E Duncan
BACKGROUND: During the past decade of conflict, numerous casualties sustained injuries requiring the formation of an ostomy. However, outcomes in those casualties undergoing ostomy reversal have yet to be analyzed. We review the experience and identify risk factors for complications after ostomy reversal in a series of combat casualties at our military treatment facility. STUDY DESIGN: A retrospective review of combat casualties managed with a diverting ostomy who underwent ostomy reversal at our military treatment facility over a 13 year period...
June 12, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29906582/is-a-unilateral-surgical-approach-effective-in-patients-with-bilateral-leg-pain-with-unilateral-lumbar-disk-herniation-a-prospective-nonrandomized-clinical-and-surgical-study
#13
Fatih Yakar, Murat Zaimoglu, Ihsan Dogan, Batuhan Bakirarar, Umit Eroglu, Cihan Kircil, Onur Ozgural, Melih Ucer, Cemil Kilinc, Altan Demirel, Efe Guner, Melih Bozkurt, Yusuf Sukru Caglar
OBJECTIVE: To examine the surgical results of unilateral lumbar discectomy in patients with bilateral leg pain and discuss short- and long-term outcomes within the limits of lumbar decompression. METHODS: We analyzed 60 patients with unilateral disk herniation who underwent unilateral lumbar discectomy and hemipartial laminectomy between 2014 and 2017. Group 1 (30 patients) had bilateral leg pain and unilateral lumbar disk herniation. Pain lateralization was determined radiologically...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29906580/posterior-lumbar-interbody-fusion-vs-dynamic-hybrid-instrumentation-a-prospective-randomised-clinical-trial
#14
C Herren, M Simons, J Bredow, S Oikonomidis, L Westermann, R Sobottke, M J Scheyerer, M Pishnamaz, P Eysel, K Zarghooni, J Franklin, J Siewe
PURPOSE: The purpose of this study was to assess the radiological and clinical outcomes following lumbar fusion intervention and to compare both, the established posterior lumbar interbody fusion (PLIF)-technique and the dynamic hybrid instrumentation ('topping off'). METHODS: In this prospective randomised trial all patients presented with degenerative changes to the lumbar spine (L2-S1) were included and randomised in two groups: patients who underwent the 360°-fusion procedure in PLIF-technique (1, control group) and those patients who underwent fusion surgery with additional hybrid instrumentation (DTO, Zimmer, Inc...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29906579/outcomes-of-aggressive-surgical-resection-in-growth-hormone-secreting-pituitary-adenomas-with-cavernous-sinus-invasion
#15
Hun Ho Park, Eui Hyun Kim, Cheol Ryong Ku, Eun Jig Lee, Sun Ho Kim
OBJECTIVE: Cavernous sinus (CS) invasion is an unfavorable factor hindering remission of growth hormone (GH)-secreting pituitary adenomas. However, few data exist on aggressive surgical resection. The authors investigate the role of CS exploration for GH-secreting pituitary adenomas with CS invasion. METHODS: We classified 132 patients with GH-secreting pituitary adenomas invading CS into 4 groups. The patients underwent surgery using a microsurgical transsphenoidal approach (TSA) with assistance of an endoscope...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29906578/immediate-and-long-term-outcomes-of-microvascular-decompression-for-mixed-trigeminal-neuralgia
#16
Adela Wu, Tina Doshi, Alice Hung, Tomas Garzon-Muvdi, Matthew T Bender, Chetan Bettegowda, Michael Lim
OBJECTIVE: Classic trigeminal neuralgia (TN) involves sharp, shooting pain in any trigeminal nerve distribution, whereas atypical TN presents with constant aching, numbness or burning that can appear with classic features, leading to a mixed presentation. Microvascular decompression (MVD) is an effective treatment for classic TN, but its utility in treating mixed TN is less studied. METHODS: We retrospectively studied 73 adult patients with mixed TN and 386 classic TN patients, who all underwent MVD between December 2007 and October 2016...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29906576/papillary-tumor-of-the-pineal-region-in-children-presentation-of-a-case-and-comprehensive-literature-review
#17
REVIEW
Joham Choque-Velasquez, Roberto Colasanti, Julio Resendiz-Nieves, Behnam Rezai Jahromi, Olli Tynninen, Juhani Collan, Mika Niemelä, Juha Hernesniemi
The papillary tumor of the pineal region (PTPR) is a rare grade II-III pineal lesion with peculiar histologic and immunohistochemical features. These tumors mostly occur in adults, rarely in children (19 cases reported up to now). We present a 3-year-old boy who was re-operated for a recurrent PTPR (grade II). The gross total resection of the lesion, through an occipital interhemispheric approach in sitting position, was followed by adjuvant radiochemotherapy. Histological examination revealed tumor progression (grade III), and the MIB-1 proliferation index was higher than 25%...
June 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29906561/multivariate-monitoring-for-the-industrialisation-of-a-continuous-wet-granulation-tableting-process
#18
Simeone Zomer, Jun Zhang, Sameer Talwar, Sayantan Chattoraj, Christopher Hewitt
The pharmaceutical industry is undergoing a significant change in product development and manufacturing strategies with the progressive shift from batch to continuous processes. These typically feature vast volumes of data generated by the numerous sensors connected to several unit operations running over the period of several hours or even days and that demand the application of increasingly efficient tools for process understanding, monitoring and control. This paper describes the use of multivariate statistical process modeling by means of chemometric methods to monitor the continuous wet granulation tableting process for a drug product currently under development...
June 12, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29906523/ventricular-fibromas-in-children-arrhythmia-risk-and-outcomes-a-multicentre-study
#19
John P Jones, Tristan Ramcharan, Milind Chaudhari, Vinay Bhole, Karen Mcleod, Shankar Sadagopan, Orhan Uzun, Andrew Parry, Jan Till, Colin J McMahon, Alan G Stuart, Mark A Walsh
BACKGROUND: Although ventricular fibromas are a rare, they are the second most common type of cardiac tumor in children. While histologically benign, they have a propensity to cause malignant arrhythmias, with cardiac arrest often being the first presentation.; OBJECTIVE: To evaluate the arrhythmia risk, and management strategies for pediatric ventricular fibromas. METHODS: Fifteen centers in the British Paediatric Arrhythmia Group network were contacted to partake in the study to contribute cases...
June 12, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29906522/evaluation-of-venous-thromboembolic-complications-in-patients-operated-on-for-pelvic-fracture
#20
Candice Ostrowka, Stéphanie Bonhomme, Pomme Jouffroy, Guillaume Riouallon
INTRODUCTION: Fractures of the pelvis (acetabulum and pelvic ring) are complex in both radiological diagnosis and therapeutic management. They show high risk of thrombosis, with variable rates of venous thromboembolic complications in the literature, ranging from 10% to 50%, with 0.5-10% risk of fatal pulmonary embolism. The objective of the present study was to determine the rate of venous thromboembolic events in a consecutive cohort of pelvic fracture and to attempt to identify thromboembolic risk factors in this population...
June 12, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
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