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https://www.readbyqxmd.com/read/29041021/a-comparison-of-outcomes-of-carpal-tunnel-release-for-carpal-tunnel-syndrome-in-patients-diagnosed-with-and-without-electrophysiological-studies
#1
Piotr Puchalski, Andrzej Zyluk, Zbigniew Szlosser
Records were analysed from the institutional database, including 943 patients (1089 hands) with CTS who were operated on in the authors' department over a period of four years (2012 to 2015). The diagnosis of CTS was made solely on the basis of clinical findings in 551 patients (58 %); 392 patients (42 %) also had electrodiagnostic tests performed, for various reasons. Patients were followed-up at 1 and 6 months with assessments that included the Levine scores, filament tests, grip and pinch strength. No significant differences in Levine scores were found at the 1 and 6 month assessments...
October 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29041004/impact-of-beta-blockade-on-cardiac-events-in-patients-with-chronic-severe-nonischemic-mitral-regurgitation
#2
Phyllis G Supino, Ofek Y Hai, Abhishek Sharma, Joshua Lampert, Clare Hochreiter, Edmund M Herrold, Jeffrey S Borer
OBJECTIVES: The aim of this study was to examine the impact of beta-blockade on cardiac events among patients with initially asymptomatic chronic severe nonischemic mitral valve regurgitation (MR). METHODS: Data from 52 consecutive patients in our prospective natural history study of isolated chronic severe nonischemic MR were assessed post hoc over 19 years to examine the relation of chronic beta-blockade use to subsequent cardiac events (death or indications for mitral valve surgery, MVS)...
October 18, 2017: Cardiology
https://www.readbyqxmd.com/read/29040995/role-of-immune-checkpoint-blockade-in-the-treatment-for-human-hepatocellular-carcinoma
#3
Naoshi Nishida, Masatoshi Kudo
With the development of molecular targeting therapy, several treatment options for advanced hepatocellular carcinoma (HCC) have become available in cases where curative and other palliative treatments, such as radiofrequency ablation, surgical resection, and transarterial chemoembolization, are not applicable. However, with the detection of a variety of mutations in cancer-related genes in a single tumor, molecular heterogeneity is commonly observed in HCC. Therefore, mutations in the major cellular signaling pathways underlie the development of resistance to molecular targeting agents...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/29040984/ability-of-cytokeratin-18-fragments-and-fib-4-index-to-diagnose-overall-and-mild-fibrosis-nonalcoholic-steatohepatitis-in-japanese-nonalcoholic-fatty-liver-disease-patients
#4
Natsuko Kobayashi, Takashi Kumada, Hidenori Toyoda, Toshifumi Tada, Takanori Ito, Masayoshi Kage, Takeshi Okanoue, Masatoshi Kudo
BACKGROUND: Several laboratory markers used in lieu of liver biopsy are reportedly useful in the diagnosis of nonalcoholic steatohepatitis (NASH). In the present study, we investigated the diagnostic impact of various non-invasive markers for predicting NASH. METHODS: A total of 229 nonalcoholic fatty liver disease (NAFLD) patients who underwent liver biopsy were enrolled for the study. The diagnostic ability of various markers to diagnose NASH from NAFLD was investigated...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/29040983/diagnosis-of-fibrosis-and-activity-by-a-combined-use-of-strain-and-shear-wave-imaging-in-patients-with-liver-disease
#5
Norihisa Yada, Nobuhura Tamaki, Yohei Koizumi, Masashi Hirooka, Osamu Nakashima, Yoichi Hiasa, Namiki Izumi, Masatoshi Kudo
OBJECTIVE: Performing shear wave imaging is simple, but can be difficult when inflammation, jaundice, and congestion are present. Therefore, the correct diagnosis of liver fibrosis using shear wave imaging alone might be difficult in mild-to-moderate fibrosis cases. Strain imaging can diagnose liver fibrosis without the influence of inflammation. Therefore, the combined use of strain and shear wave imaging (combinational elastography) for cases without jaundice and congestion might be useful for evaluating fibrosis and inflammation...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/29040949/phenomenological-characteristics-of-recovered-memory-in-nonclinical-individuals
#6
Chui-De Chiu
A central hypothesis of recovered memory is that the source of the memory may be misattributed, and the memory of an imagined event may be mistaken as the memory of the perceived event that was not remembered. The judgment of memory source depends upon phenomenological characteristics. Thus, the present study investigated characteristics of recovered memory. To exclude potential confounding effects of traumatic stress and acute mental illness, data on recovered memories of diverse valences in a nonclinical sample were collected...
October 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29040943/liquid-chromatography-tandem-mass-spectrometry-direct-injection-analysis-of-organophosphorus-flame-retardants-in-ontario-surface-water-and-wastewater-effluent
#7
Chunyan Hao, Paul A Helm, David Morse, Eric J Reiner
Organophosphorus flame retardants (OPFRs) started to be used in plastics, electronics and furnishings back in the 1960s and became popular again last decade. They are now widely present in the environment and regarded as "new" emerging organic pollutants. An effective liquid chromatography-tandem mass spectrometry (LC-MS/MS) direct injection analysis (DIA) method was developed to monitor OPFR levels in aquatic environment. The removal of sample extraction and concentration steps not only improved operation efficiency, but also reduced the potential contamination commonly observed during the sample preparation process before...
October 10, 2017: Chemosphere
https://www.readbyqxmd.com/read/29040906/a-case-report-of-choledocholithiasis-33-years-after-cholecystectomy
#8
Xane Peters, Gannavarapu Bhargava, Antonio Gangemi
INTRODUCTION: Choledocholithiasis after cholecystectomy is rare and often attributed to surgical clip migration and subsequent nidus formation. PRESENTATION OF CASE: This case demonstrates choledocholithiasis following cholecystectomy with a latency period of 33 years. DISCUSSION: The patient presented with pain of the right upper quadrant (RUQ). Subsequent abdominal-pelvic CT imaging revealed dilation of the common bile duct. Further Endoscopic Retrograde Cholangiopancreatography was indicative of choledocholithiasis...
October 12, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29040905/bilateral-methachronous-testicular-germ-cell-tumor-and-testicular-microlithiasis-in-a-child-genetic-analysis-and-insights-a-case-report
#9
N Boudaoud, G Loron, M Pons, E Landais, S Kozal, M Doco-Fenzy, M L Poli-Merol
OBJECTIVES: To report our experience with a case of a child with bilateral testicular micro-lithiasis (TML) who developed bilateral metachronous testicular germ cell tumor (TGCT) and determine the most appropriate follow-up and care management in children with testicular micro calcifications in regards to the theoretical risk of testicular cancer. CASE REPORT: A 12 year-old boy was diagnosed with TGCT and TML. Ten years after complete remission, he presented with a recurrence on the contralateral testis...
October 14, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29040904/malignant-fibrous-histiocytoma-in-the-right-portion-of-the-mandible-with-metastasis-in-pancreas
#10
Javier Biurrun Chamale, Marco Bruno, Facundo Mandojana, Llugdar José, Lucas Armando, Doniquian Alejandro
BACKGROUND: Malignant fibrous histiocytoma is a sarcoma of uncertain origin that can be found both in soft tissues and in bones. It is currently called undifferentiated pleomorphic sarcoma not otherwise specified and it represents a final common pathway in several tumors that are subject to the progress of dedifferentiation. Local recurrence of the tumor in the same location where it was originated occurs in 20-30% of the total number of soft tissue sarcomas. It is less frequent in limbs and more likely to recur in retroperitoneal sarcomas and in head and neck...
October 12, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29040893/quality-of-online-information-on-breast-cancer-treatment-options
#11
Nadia Arif, Pietro Ghezzi
Offering breast cancer patients treatment choice has become a priority as the involvement of patients in the decision-making process is associated with improved physical and psychological outcomes. As the Internet is increasingly being used by patients as a source of medical information, it is important to evaluate the quality of information relating to breast cancer on the Internet. We analysed 200 websites returned by google.co.uk searching "breast cancer treatment options" in terms of their typology and treatment options described...
October 14, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29040892/majority-of-flat-epithelial-atypia-diagnosed-on-biopsy-do-not-require-surgical-excision
#12
Patrick Mun Yew Chan, Niketa Chotai, Eileen Shujuan Lai, Pei Yi Sin, Juliana Chen, Sarah Qinghui Lu, Mui Heng Goh, Bee Kiang Chong, Bernard Chi Shern Ho, Ern Yu Tan
BACKGROUND: Borderline risk lesions such as flat epithelial atypia (FEA) are increasingly being diagnosed on biopsy. The need for surgery is being debated. In this study, we determined the frequency of histological upgrade following a diagnosis of FEA on biopsy and evaluated potential predictive factors. METHODS: Retrospective review was done of 194 women who underwent biopsy of indeterminate lesions (total 195 lesions) that were diagnosed as FEA. The review covered a 10-year period...
October 14, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29040863/high-tolerance-of-and-removal-of-cefazolin-sodium-in-single-chamber-microbial-fuel-cells-operation
#13
Enren Zhang, Qingling Yu, Wenjing Zhai, Feng Wang, Keith Scott
Single-chamber microbial fuel cells (MFCs) have been shown to be a promising approach for cefazolin sodium (CFZS)-contaminated wastewater treatment, in terms of electricity production, high CFZS tolerance and effective CFZS removal. MFCs exposed to CFZS loadings up to 100 mg L(-1), produced stable power of 18.2 ± 1.1 W m(-3) and a maximum power of 30.4 ± 2.1 W m(-3), similar to that of CFZS-free MFCs (stable power 19.4 ± 0.8 W m(-3) and maximum power 32.5 ± 1.6 W m(-3)), notwithstanding a longer acclimitisation MFC activation...
October 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29040861/biomimetic-aquaporin-membranes-for-osmotic-membrane-bioreactors-membrane-performance-and-contaminant-removal
#14
Wenhai Luo, Ming Xie, Xiaoye Song, Wenshan Guo, Hao H Ngo, John L Zhou, Long D Nghiem
In this study, we investigated the performance of an osmotic membrane bioreactor (OMBR) enabled by a novel biomimetic aquaporin forward osmosis (FO) membrane. Membrane performance and removal of 30 trace organic contaminants (TrOCs) were examined. Results show that the aquaporin FO membrane had better transport properties in comparison with conventional cellulose triacetate and polyamide thin-film composite FO membranes. In particular, the aquaporin FO membrane exhibited much lower salt permeability and thus smaller reverse salt flux, resulting in a less severe salinity build-up in the bioreactor during OMBR operation...
September 27, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29040848/responses-of-microbial-community-to-ph-stress-in-bioleaching-of-low-grade-copper-sulfide
#15
Yuguang Wang, Kai Li, Xinhua Chen, Hongbo Zhou
The microbial diversity and dynamics in the leachates and on the ore surfaces of different depth of the column were analyzed during bioleaching of low grade copper sulfide at different pH, after inoculation with the same inoculum containing mesophiles and moderate thermophiles. The results indicate that low pH was beneficial to enhance copper extraction. The highest copper extraction (86%) was obtained when pH was controlled at 1.0-1.5. The microbial structures on the ore surfaces were independent of community structures in the leachate, even at the top portion of column...
October 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29040840/experiences-of-structural-vulnerability-among-exotic-dancers-in-baltimore-maryland-co-occurring-social-and-economic-antecedents-of-hiv-sti-risk
#16
Meredith L Brantley, Katherine H A Footer, Sahnah Lim, Deanna Kerrigan, Susan G Sherman
BACKGROUND: Women who grow up in economic scarcity often face limited opportunities for upward mobility, as a result of challenges securing stable housing, quality education, and steady employment. Chronic instability may limit the capacity of women to protect themselves against HIV/STI-related harm when engaging in sexual activity or drug use. Characterizing the structural contexts that facilitate HIV/STI risk among women are critical to effective design and implementation of drug and sexual harm reduction interventions...
October 14, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29040834/effect-of-oil-structure-on-cyclodextrin-based-pickering-emulsions-for-bupivacaine-topical-application
#17
Jiun-Wen Hu, Mei-Wen Yen, Ae-June Wang, I-Ming Chu
Cyclodextrins (CDs) coupled with oils forms an insoluble inclusion complex that is able to adsorb to the interface between oils and aqueous phases; it thereby stabilizes Pickering emulsions. Three types of oils (triglyceride, linear chain oil, and ring-structured oil) were chosen to work with CDs to prepare bupivacaine (BPC)-encapsulated Pickering emulsions. We also investigated the relationship between oils and CDs; as well as their influences on stability, drug-releasing capability and skin permeability. Particle sizes and microstructures were determined by dynamic light scattering and scanning electron microscopy, respectively...
October 4, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29040828/neuropsychological-functioning-and-brain-energetics-of-drug-resistant-mesial-temporal-lobe-epilepsy-patients
#18
Camila Moreira Osório, Alexandra Latini, Rodrigo Bainy Leal, Maria Emília Rodrigues de Oliveira Thais, Helena Dresch Vascouto, Aline Pertile Remor, Mark William Lopes, Marcelo Neves Linhares, Juliana Ben, Roberta de Paula Martins, Rui Daniel Prediger, Alexandre Ademar Hoeller, Hans Joachim Markowitsch, Peter Wolf, Kátia Lin, Roger Walz
Interictal hypometabolism is commonly measured by 18-fluoro-deoxyglucose Positron Emission Tomography (FDG-PET) in the temporal lobe of patients with mesial temporal lobe epilepsy (MTLE-HS). Left temporal lobe interictal FDG-PET hypometabolism has been associated with verbal memory impairment, while right temporal lobe FDG-PET hypometabolism is associated with nonverbal memory impairment. The biochemical mechanisms involved in these findings remain unknown. In comparison to healthy controls (n=21), surgically treated patients with MTLE-HS (n=32, left side=17) had significant lower scores in the Rey Auditory Verbal Learning Test (RAVLT retention and delayed), Logical Memory II (LMII), Boston Naming test (BNT), Letter Fluency and Category Fluency...
October 12, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29040794/evaluating-the-peptide-structure-prediction-capabilities-of-a-purely-ab-initio-method
#19
M Amitay, M Goldstein
DEEPSAM is a relatively new global optimization algorithm aimed to predict the structure of bio-molecules from sequence, without any additional preliminary assumption. It is an evolutionary algorithm whose mutation operators are built by hybridizing the diffusion equation method, molecular dynamics simulated annealing, and a quasi-Newton local minimization method. The goal of this study was to evaluate the structure prediction capabilities of DEEPSAM by running it upon NMR structures of linear peptides (10-20 residues)...
October 13, 2017: Protein Engineering, Design & Selection: PEDS
https://www.readbyqxmd.com/read/29040777/efficient-imaging-examining-the-value-of-ultrasound-in-the-diagnosis-of-traumatic-adult-brachial-plexus-injuries-a-systematic-review
#20
Brian Chin, Maleka Ramji, Forough Farrokhyar, James R Bain
INTRODUCTION: Traumatic brachial plexus injury (BPI) can result in debilitating sequelae of the upper extremity. Presently, therapeutic decisions are based on the mechanism of injury, serial physical examination, electromyography, nerve conduction, and imaging studies. While magnetic resonance imaging is the current imaging modality of choice for BPI, ultrasound is a promising newcomer that is inexpensive, accessible, and available at point of care. OBJECTIVE: To evaluate ultrasound as a diagnostic tool in the assessment of traumatic adult BPI through a systematic review...
October 11, 2017: Neurosurgery
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