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https://www.readbyqxmd.com/read/29055288/osteoinductive-effects-of-cyplexinol-in-the-management-of-osteoporosis-a-case-series
#1
Daniel Tripodi
Aims • A case study was conducted on a subject with a history of documented bone loss and the observed outcome of bone mineral density (BMD) changes when utilizing supplementation with Cyplexinol, a natural bone morphogenetic protein complex. Method and Results • A case of osteoporosis was reviewed with pertinent medical history and dual energy X-ray absorptiometry history described both pre- and postsupplementation. Results demonstrated a significant change in bone density parameter for the individual when the bone support supplement, Cyplexinol, was used...
October 21, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29055269/decision-making-measured-by-the-iowa-gambling-task-in-alcohol-use-disorder-and-gambling-disorder-a-systematic-review-and-meta-analysis
#2
REVIEW
Ildikó Kovács, Mara J Richman, Zoltán Janka, Aniko Maraz, Bálint Andó
BACKGROUND AND AIMS: Gambling disorder (GD) and alcohol use disorder (AD) have similar features, such as elevated impulsivity and decision-making deficits, which are directly linked to relapse and poor therapeutic outcomes. Our aim was to assess decision-making characteristics in GD and AD patients compared to healthy controls (HC) based on one of the most frequently used measures of decision-making: the Iowa Gambling Task (IGT). METHODS: In our systematic literature search of three databases, we identified 1198 empirical articles that mentioned decision-making deficits with the use of the IGT in patients diagnosed with either AD or GD...
October 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055208/measuring-alcohol-use-across-the-transition-to-adulthood-racial-ethnic-sexual-identity-and-educational-differences
#3
Jessica N Fish, Amanda M Pollitt, John E Schulenberg, Stephen T Russell
BACKGROUND: Patterns of alcohol use change from adolescence to adulthood and may differ based on race/ethnicity, sexual identity, and education. If alcohol use measures do not operate consistently across groups and developmental periods, parameter estimates and conclusions may be biased. OBJECTIVES: To test the measurement invariance of a multi-item alcohol use measure across groups defined by race/ethnicity, sexual identity, and college education during the transition to adulthood...
October 12, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29055193/specific-bioanalytical-optical-and-photoelectrochemical-assays-for-detection-of-methanol-in-alcoholic-beverages
#4
Javier Barroso, Beatriz Díez-Buitrago, Laura Saa, Marco Möller, Nerea Briz, Valeri Pavlov
Methanol is a poison which is frequently discovered in alcoholic beverages. Innovative methods to detect methanol in alcoholic beverages are being constantly developed. We report for the first time a new strategy for the detection of methanol using fluorescence spectroscopy and photoelectrochemical (PEC) analysis. The analytical system is based on the oxidation of cysteine (CSH) with hydrogen peroxide (H2O2) enzymatically generated by alcohol oxidase (AOx). H2O2 oxidizes capping agent CSH, modulating the growth of CSH-stabilized cadmium sulphide quantum dots (CdS QDs)...
October 13, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29055104/lifetime-alcohol-intake-and-risk-of-non-hodgkin-lymphoma-findings-from-the-melbourne-collaborative-cohort-study
#5
Harindra Jayasekara, Surender Juneja, Allison M Hodge, Robin Room, Roger L Milne, John L Hopper, Dallas R English, Graham G Giles, Robert J MacInnis
Cohort studies have reported inconsistent evidence regarding alcohol intake and risk of non-Hodgkin lymphoma (NHL), mostly based on alcohol intake assessed close to study enrolment. We examined this association using alcohol intake measured from age 20 onwards. We calculated usual alcohol intake for 10-year periods from age 20 using recalled frequency and quantity of beverage-specific consumption for 37,990 participants aged 40-69 years from the Melbourne Collaborative Cohort Study. Cox regression was performed to derive hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between alcohol intake (g/day) and NHL risk...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29055095/the-joint-effects-of-major-lifestyle-factors-on-colorectal-cancer-risk-among-chinese-men-a-prospective-cohort-study
#6
Qing-Li Zhang, Long-Gang Zhao, Hong-Lan Li, Jing Gao, Gong Yang, Jing Wang, Wei Zheng, Xiao-Ou Shu, Yong-Bing Xiang
Previous studies have suggested individual healthy lifestyle factors are related to lower risk of colorectal cancer. Their joint effects, however, have rarely been investigated. We aimed to assess the combined lifestyle impact on colorectal cancer risk and to estimate the population attributable risks of these lifestyle factors. Using data from the Shanghai Men's Health Study (2002-2013), we constructed healthy lifestyle index composing the following lifestyle factors: smoking, alcohol consumption, diet, waist-hip ratio and exercise participation...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29055049/pax9-regulates-squamous-cell-differentiation-and-carcinogenesis-in-the-oro-esophageal-epithelium
#7
Zhaohui Xiong, Shuang Ren, Hao Chen, Yao Liu, Caizhi Huang, Yawan Lyvia Zhang, Joab Otieno Odera, Tong Chen, Ralf Kist, Heiko Peters, Katherine Garman, Zheng Sun, Xiaoxin Chen
PAX9 is a transcription factor of the PAX family characterized by a DNA-binding paired domain. Previous studies have suggested a potential role of PAX9 in squamous cell differentiation and carcinogenesis of the oro-esophageal epithelium. However, its functional roles in differentiation and carcinogenesis remain unclear. In this study, Pax9 deficiency in the mouse esophagus promoted cell proliferation, delayed cell differentiation and altered the global gene expression profile. Ethanol exposure down-regulated PAX9 expression in human esophageal epithelial cells in vitro and mouse forestomach and tongue in vivo...
October 21, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/29054954/cerebellar-ataxia-and-neuropathy-as-presenting-features-of-hepatitis-b-related-cirrhosis-and-portal-hypertension
#8
Arunmozhi Elavarasi, Deepa Dash, Manjari Tripathi, Rohit Bhatia
Adult onset cerebellar dysfunction with neuropathy is a commonly encountered condition and is usually due to genetic causes such as spinocerebellar ataxia, gluten ataxia, alcohol related, toxic, degenerative, immune mediated, paraneoplastic causes and so on. Ataxia and neuropathy as presenting features of hepatitis-B related liver disease are very rare and have not been reported so far.
October 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29054845/does-moderate-drinking-increase-the-risk-of-atrial-fibrillation-the-norwegian-hunt-nord-tr%C3%A3-ndelag-health-study
#9
Katalin Gémes, Vegard Malmo, Lars Erik Laugsand, Jan Pål Loennechen, Hanne Ellekjaer, Krisztina D László, Staffan Ahnve, Lars J Vatten, Kenneth J Mukamal, Imre Janszky
BACKGROUND: Compelling evidence suggests that excessive alcohol consumption increases the risk of atrial fibrillation (AF), but the effect of light-moderate alcohol consumption is less certain. We investigated the association between alcohol consumption within recommended limits and AF risk in a light-drinking population. METHODS AND RESULTS: Among 47 002 participants with information on alcohol consumption in a population-based cohort study in Norway, conducted from October 2006 to June 2008, 1697 validated AF diagnoses were registered during the 8 years of follow-up...
October 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29054839/incremental-prognostic-utility-of-left-ventricular-global-longitudinal-strain-in-hypertrophic-obstructive-cardiomyopathy-patients-and-preserved-left-ventricular-ejection-fraction
#10
Albree Tower-Rader, Jorge Betancor, Zoran B Popovic, Kimi Sato, Maran Thamilarasan, Nicholas G Smedira, Harry M Lever, Milind Y Desai
BACKGROUND: In obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV-GLS) provided incremental prognostic utility. METHODS AND RESULTS: We studied 1019 patients with documented hypertrophic cardiomyopathy (mean age, 50±12 years; 63% men) evaluated at our center between 2001 and 2011. We excluded age <18 years, maximal LV outflow tract gradient <30 mm Hg, bundle branch block or atrial fibrillation, past pacemaker/cardiac surgery, including myectomy/alcohol ablation, and obstructive coronary artery disease...
October 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29054575/emergency-department-presentations-by-older-people-for-mental-health-or-drug-and-alcohol-conditions-a-multicentre-retrospective-audit
#11
Margaret Fry, Steve Kay, Rosalind M Elliott
PURPOSE: Emergency department presentations by older people associated with mental health and drug and alcohol related conditions are increasing. However, the characteristics of presentations by older people in Australia are largely unknown. The aim of this research was to explore the characteristics of older people presenting with mental health and drug and alcohol conditions. PROCEDURES: We used a retrospective electronic medical record audit to explore all emergency department presentations by older people 65 years and over for mental health and drug and alcohol related conditions over a 12 month period...
October 17, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/29054502/epidemiology-and-risk-factors-of-uterine-fibroids
#12
REVIEW
Dora Pavone, Sara Clemenza, Flavia Sorbi, Massimiliano Fambrini, Felice Petraglia
Risk factors, both modifiable and non-modifiable, are associated with the development of fibroids. These include age, race, endogenous and exogenous hormonal factors, obesity, uterine infection, and lifestyle (diet, caffeine and alcohol consumption, physical activity, stress, and smoking). Some of the epidemiological data were conflicting; consequently, further studies are needed to better understand the factors that influence fibroid prevalence.
October 1, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29054392/impairment-of-manual-but-not-saccadic-response-inhibition-following-acute-alcohol-intoxication
#13
Anne Eileen Campbell, Christopher D Chambers, Christopher P G Allen, Craig Hedge, Petroc Sumner
BACKGROUND: Alcohol impairs response inhibition; however, it remains contested whether such impairments affect a general inhibition system, or whether affected inhibition systems are embedded in, and specific to, each response modality. Further, alcohol-induced impairments have not been disambiguated between proactive and reactive inhibition mechanisms, and nor have the contributions of action-updating impairments to behavioural 'inhibition' deficits been investigated. METHODS: Forty Participants (25 female) completed both a manual and a saccadic stop-signal reaction time (SSRT) task before and after a 0...
September 20, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29054352/patient-related-risk-factors-for-infection-following-open-carpal-tunnel-release-an-analysis-of-over-450-000-medicare-patients
#14
Brian C Werner, Victor A Teran, D Nicole Deal
PURPOSE: To establish the rate of postoperative infection after open carpal tunnel release (CTR) on a national level using an administrative database and define relevant patient-related risk factors associated with its occurrence. METHODS: The PearlDiver patient records database was used to query the 100% Medicare Standard Analytic Files retrospectively from 2005 to 2012 for patients undergoing open CTR using Current Procedural Terminology code 64721. Postoperative infection within 90 days of surgery was assessed using both International Classification of Diseases, Ninth Revision codes for diagnoses of postoperative infection or pyogenic arthritis of the wrist and Current Procedural Terminology codes for procedures for these indications, including either open or arthroscopic irrigation and debridement...
October 18, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29054291/neuroscience-informed-psychoeducation-for-addiction-medicine-a-neurocognitive-perspective
#15
Hamed Ekhtiari, Tara Rezapour, Robin L Aupperle, Martin P Paulus
Psychoeducation (PE) is defined as an intervention with systematic, structured, and didactic knowledge transfer for an illness and its treatment, integrating emotional and motivational aspects to enable patients to cope with the illness and to improve its treatment adherence and efficacy. PE is considered an important component of treatment in both medical and psychiatric disorders, especially for mental health disorders associated with lack of insight, such as alcohol and substance use disorders (ASUDs). New advancements in neuroscience have shed light on how various aspects of ASUDs may relate to neural processes...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29054077/relationship-between-empathic-processing-and-drinking-behavior-in-project-match
#16
Charles S H Robinson, Kathryn Fokas, Katie Witkiewitz
INTRODUCTION: Family relationships, social connectedness and a greater network of supportive others each predict better drinking outcomes among individuals with alcohol use disorder (AUD). The association between social factors and drinking may be related to the ability of individuals to take the perspectives of others' mental and emotional states, defined as empathic processing (EP). As such, it may be the case that EP is associated with social support (SS) and drinking behavior among individuals with AUD, yet few prior studies have attempted to define EP in an AUD sample...
October 3, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29054000/when-does-alcohol-hurt-a-driving-simulator-study
#17
Mark Vollrath, Josefine Fischer
World-wide, alcohol is still a major cause of traffic accidents. The dose-related accident risk function has been found in a large number of risk studies. A plethora of laboratory studies has examined the effect of alcohol with regard to different information processing capabilities of drivers. Summarizing the results, alcohol effects occur at lower blood alcohol concentrations (BAC) the more complex the tasks get. However, in contrast, typical alcohol-related crashes are frequently single vehicle crashes but not so often crashes in complex situations like at intersections...
October 17, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29053985/rapid-cultivation-of-free-living-planktonic-anammox-cells
#18
Lei Zhang, Satoshi Okabe
Despite that anaerobic ammonium oxidizing (anammox) bacteria are key players in the global nitrogen cycle, no pure cultures are still available. Planktonic cell culture with high purity is, therefore, essential for physiological and biochemical studies of anammox bacteria. However, development of such planktonic cell cultures requires an enormous amount of time and effort. Here we developed a novel rapid method for cultivating free-living planktonic anammox cells. First, anammox granules were physically dispersed, immobilized in 6% polyvinyl alcohol-4% sodium alginate (PVA-SA) gel beads, and then pre-cultured in an up-flow column reactor...
October 15, 2017: Water Research
https://www.readbyqxmd.com/read/29053935/capsaicin-the-pungent-principle-of-peppers-ameliorates-alcohol-induced-acute-liver-injury-in-mice-via-modulation-of-matrix-metalloproteinases
#19
Meghana Koneru, Bidya Dhar Sahu, Salma Mukhtar Mir, Halley Gora Ravuri, Madhusudana Kuncha, Jerald Mahesh Kumar, Eswar Kumar Kilari, Ramakrishna Sistla
Alcohol, the most common cause for hepatic injury, may further deteriorate the hepatic tissue when left unattended. Capsaicin, the pungent principle of chilli-peppers, possesses antioxidant and anti-inflammatory properties and is a proven dietary antioxidant in various ailments. However, its role in alcohol induced hepatic injury is unclear. In this study, we investigated the effects of capsaicin on the hepatic tissue of mice treated with alcohol. Acute liver injury was induced in mice by oral gavage of 5 doses of 10 ml/kg of 50% ethyl alcohol at an interval of 12 hours each...
October 20, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29053832/reward-deficits-in-behavioural-variant-frontotemporal-dementia-include-insensitivity-to-negative-stimuli
#20
David C Perry, Samir Datta, Virginia E Sturm, Kristie A Wood, Jessica Zakrzewski, William W Seeley, Bruce L Miller, Joel H Kramer, Howard J Rosen
During reward processing individuals weigh positive and negative features of a stimulus to determine whether they will pursue or avoid it. Though patients with behavioural variant frontotemporal dementia display changes in their pursuit of rewards, such as food, alcohol, money, and sex, the basis for these shifts is not clearly established. In particular, it is unknown whether patients' behaviour results from excessive focus on rewards, insensitivity to punishment, or to dysfunction in a particular stage of reward processing, such as anticipation, consumption, or action selection...
October 7, 2017: Brain: a Journal of Neurology
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