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https://www.readbyqxmd.com/read/29927865/infant-feeding-practices-and-the-effect-in-reducing-functional-constipation-six-years-later-a-randomised-field-trial
#1
Caroline Nicola Sangalli, Paula Dos Santos Leffa, Mauro Batista de Morais, Márcia Regina Vitolo
OBJECTIVE: To assess the impact of health worker training on infant feeding practices on the prevalence of functional constipation among children at six years of age. METHODS: Cluster randomised field trial conducted in Porto Alegre, Brazil. Health centers were randomly allocated into intervention (n = 9) or control (n = 11) groups. In intervention sites, health workers joined training sessions on the "Ten Steps for Healthy Feeding for Children from Birth to Two Years of age"...
June 20, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29914714/prevalence-of-functional-gastrointestinal-disorders-among-adolescents-in-buenos-aires-argentina
#2
L G Nelissen, I J N Koppen, F R Follett, C Boggio-Marzet, M Saps, K Garzon, M A Benninga
INTRODUCTION AND AIMS: The prevalence of functional gastrointestinal disorders (FGIDs) in Argentinean children and adolescents has not yet been studied. Our aim was to determine the prevalence of FGIDs among children and adolescents in Argentina using the Rome III diagnostic criteria. MATERIALS AND METHODS: A total of 483 children, 12-18 years of age, from 3 private schools and 3 public schools, were included in the study. Each child completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III), which is an age-appropriate and previously validated instrument for diagnosing FGIDs according to the Rome III criteria...
June 15, 2018: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29914250/comparison-of-prognostic-systems-in-cirrhotic-patients-with-hepatic-encephalopathy
#3
Adnan Taş, Mehmet Suat Yalçın, Bünyamin Sarıtaş, Banu Kara
Background/aim: There are various scoring systems for evaluating prognosis in patients hospitalized in intensive care units (ICUs) with hepatic encephalopathy. These include the Child-Turcotte-Pugh (CTP) classification, Model for End-stage Liver Disease (MELD), chronic liver failure-sequential organ failure assessment (CLIF-SOFA), and Acute Physiology and Chronic Health Evaluation II (APACHE II). In this study, we aimed to compare the various scoring systems to determine the best system for showing the prognosis of patients with a prior diagnosis of cirrhosis who were hospitalized for hepatic encephalopathy...
June 14, 2018: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29899371/a-heterozygous-microdeletion-of-20q13-13-encompassing-adnp-gene-in-a-child-with-helsmoortel-van-der-aa-syndrome
#4
Minh-Tuan Huynh, Elise Boudry-Labis, Alfred Massard, Caroline Thuillier, Bruno Delobel, Bénédicte Duban-Bedu, Catherine Vincent-Delorme
Helsmoortel-van der Aa (SWI/SNF autism-related or ADNP syndrome) is an autosomal dominant monogenic syndrome caused by de novo variants in the last exon of ADNP gene and no deletions have been documented to date. We report the first case of a 3 years and 10 months old boy exhibiting typical features of ADNP syndrome, including intellectual disability, autistic traits, facial dysmorphism, hyperlaxity, mood disorder, behavioral problems, and severe chronic constipation. 60K Agilent array-comparative genomic hybridization (CGH) identified a heterozygous interstitial microdeletion at 20q13...
June 13, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29801510/currarino-syndrome-and-microcephaly-due-to-a-rare-7q36-2-microdeletion-a-case-report
#5
Lucia Cococcioni, Susanna Paccagnini, Elena Pozzi, Luigina Spaccini, Elisa Cattaneo, Serena Redaelli, Francesca Crosti, Gian Vincenzo Zuccotti
BACKGROUND: Currarino syndrome is a rare condition characterized by presacral mass, anorectal malformation and sacral dysgenesis. CASE PRESENTATION: We report the case of a child that presented chronic constipation, encopresis and mycrocephaly. The characteristics were initially compatible with a case of functional constipation and a therapy with polyethylene glycol was prescribed. After a year, because of poor response, a plain abdominal X-ray was performed, detecting sacrum abnormalities...
May 25, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29779292/paediatric-constipation-an-approach-and-evidence-based-treatment-regimen
#6
Harveen Singh, Frances Connor
BACKGROUND: Constipation affects 5-30% of children and is responsible for 3% of primary care visits. General practitioners (GPs) are frequently the first medical encounter for concerned parents regarding their child's bowel habit. OBJECTIVE: The aim of this article is to review the assessment and management of children with constipation to empower GPs to initiate treatment and know when to refer to a paediatrician. DISCUSSION: In the absence of organic aetiology, childhood constipation is almost always functional and often due to painful bowel movements that prompt the child to withhold stool...
May 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29764827/not-so-mass-effect-finding-of-a-remarkable-incidentaloma-in-a-teenager-with-neurofibromatosis
#7
Daniel John Keen, Hannah Norman-Bruce, Salah Mansy
A 13-year-old boy with neurofibromatosis type 1 presented to the emergency department twice in a fortnight with moderate intermittent abdominal pain, radiating to the back and associated with nausea and vomiting. He examined as a well child with a soft abdomen and minimal tenderness. A history of constipation was identified but he failed to respond to a trial of laxatives. Subsequent ultrasound abdomen demonstrated a large mass surrounding the porta hepatis. MRI further characterised a focal, non-aggressive lesion extending from his liver, encapsulating his pancreas, portal vessels and laterally displacing his spleen and left kidney...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29748737/psychosocial-risks-for-constipation-and-soiling-in-primary-school-children
#8
Carol Joinson, Mariusz T Grzeda, Alexander von Gontard, Jon Heron
To examine prospective associations between psychosocial problems and childhood constipation and soiling. We used latent classes of constipation and soiling ('constipation alone', 'soiling alone', 'constipation with soiling') extracted from longitudinal maternally reported data on constipation (4-10 years) and soiling (4-9 years) from 8435 children (4353 males, 4082 females) from the ALSPAC cohort. We examined the association between maternally reported psychosocial problems at 2-3 years (difficult temperament, behaviour/emotional problems, temper tantrums, behavioural sleep problems and stressful events) and the latent classes using multinomial logistic regression adjusted for a range of confounders relating to the child and family (reference category = normative latent class with very low probability of constipation/soiling)...
May 10, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29746360/laxative-induced-contact-dermatitis
#9
Jennifer E Melvin, Robert W Hickey
A 5-year-old female with Charcot-Marie-Tooth neuropathy and a history of constipation presented to the emergency department with a new blistering buttocks rash, which was initially concerning for nonaccidental burn. Upon further investigation, it was found that Ex-Lax had been given to the patient for constipation. This had resulted in a bowel movement, which led to an irritant dermatitis. The patient was eventually diagnosed with senna-induced erosive diaper dermatitis. This case report highlights the importance of a thorough history and physical examination to prevent an unnecessary child abuse work-up...
May 9, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29729176/-comparative-characteristic-of-functional-gastrocerebral-disorders-in-donors-and-premature-infants
#10
Luydmila V Ignatko, Andriiana O Yankovska, Gabriela G Kavulya, Olena V Debretseni, Kristian O Debretseni, Nataliia M Hema-Bahyna, Agneta V Lenchenko
OBJECTIVE: Introduction: Functional gastrocerebral disorders (FGCD) occupy one of the leading places in the structure of diseases of digestive organs in young children. Functional gastrointestinal disorders are accompanied by various combinations of persistent or recurrent gastrointestinal symptoms without structural or biochemical disorders. They can accompany the normal development of the child and depend on organ's disorders on the background of autonomic dysfunction, psycho-emotional and humoral factors...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29725927/how-to-establish-a-successful-bowel-management-programme-in-children-a-tertiary-paediatric-centre-experience
#11
Ann M Costigan, Stephanie Orr, Abdulrahman E Alshafei, Brice A Antao
BACKGROUND: Bowel management is a term used to describe a medical approach to the management of faecal incontinence. AIMS: To present the outcomes of an individualised bowel management programme developed by a tertiary paediatric centre and evaluate contributory factors for successful bowel management in children. METHODS: A retrospective review of children attending a bowel management clinic in a tertiary centre in Dublin, Ireland, over 5 years (2010-2015)...
May 3, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29714428/parents-views-on-toilet-training-a-cross-sectional-study-in-flanders
#12
Tinne Van Aggelpoel, Stefan De Wachter, Guido Van Hal, Kelly Van der Cruyssen, Hedwig Neels, Alexandra Vermandel
AIMS: The goals of this research were to investigate parents' perceptions of toilet training and their beliefs and views on how to toilet train children. METHODS: Questionnaires were provided to parents of healthy children, aged 18-72 months, who were or had just finished toilet training. There were 928 questionnaires returned (38% response rate). After correcting for age compliance with the range stated in the study, 832 parents remained. RESULTS: The data confirm a postponement of the age at which children start to potty train and the age at which they are toilet training...
May 11, 2018: Nursing Children and Young People
https://www.readbyqxmd.com/read/29713606/usefulness-of-assessment-of-stool-form-by-the-modified-bristol-stool-form-scale-in-primary-care-pediatrics
#13
Reema Gulati, Arpitha Komuravelly, Stephen Leb, Maroun J Mhanna, Abdullah Ghori, Janeen Leon, Robert Needlman
Purpose: Rome criteria are considered the gold standard for diagnosing functional constipation. The modified Bristol stool form scale (m-BSFS) was validated to measure stool form in children. However, neither the potential use of the m-BSFS as a tool to facilitate the diagnosis of potential constipation, nor the agreement between m-BSFS and stool consistency by Rome has been studied. Our objective is to determine if m-BSFS is a reliable tool to facilitat detection of constipation; and the agreement between stool form by m-BSFS and hard stool criteria in Rome...
April 2018: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/29705462/opinions-and-observations-of-caregivers-of-children-with-cerebral-palsy-about-changes-seen-after-reflexology-a-qualitative-study
#14
Filiz Özkan, Handan Zincir
The aim of this research was to examine the effect of reflexology on the problems of children with cerebral palsy from perspective of caregivers. Qualitative study was made after 24-session reflexology program. 12 caregivers who have 2-18 year-old children with spastic type cerebral palsy receiving special education and received reflexology. The thematic questions were determined and in-depth interviews were conducted. Themes of the study were determined as; the caregiver's views on reflexology, the effect of reflexology on health of children with CP and the caregivers' observations on child after reflexology therapy, positive and negative aspects and causes of reflexology treatment...
May 2018: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29692663/uncommon-reasons-of-the-digestive-tract-related-paraneoplastic-syndromes-in-children-with-neuroblastic-tumors-three-case-reports
#15
Elżbieta Czkwianianc, Beata Zalewska-Szewczyk, Józef Kobos, Anna Socha-Banasiak, Szymon Janczar, Sylwia Prymus-Kasińska, Joanna Kazanek-Zasada, Wojciech Młynarski
Aim of the study: presentation of the uncommon paraneoplastic syndromes related to the gastrointestinal tract that may occur in children with neuroblastic tumors and their impact on the disease course. Material and methods: Retrospective analysis of three cases of patients mainly with digestive tract-related symptoms, who were originally admitted to the gastroenterology department from 2013 to 2016 and were finally diagnosed with neuroblastic tumors. Results: The clinical data analysis showed that the symptoms from gastrointestinal tract were dominant in analyzed subjects...
2018: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29681704/cytomegalovirus-as-a-cause-of-colonic-stricture-simulating-hirschsprung-s-disease
#16
Chiranjiv Kumar, Meera Luthra
Colonic stenosis/atresias account for only 5%-15% of all atresias. Colonic stenosis is rarer than atresia and mostly occurs in ascending and transverse colon. Gastrointestinal sequelae of cytomegalovirus (CMV) are rare, frequently requires surgical intervention for diagnosis and management. We describe a 5-month-old female child with complaints of recurrent abdominal distension, vomiting, and constipation for 2 months simulating Hirschsprung's disease. After barium enema, the baby was taken up for surgery. Intraoperatively, we found a colonic stricture in the descending colon...
April 2018: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/29669175/antidepressants-for-preventing-postnatal-depression
#17
REVIEW
Emma Molyneaux, Laurence A Telesia, Carol Henshaw, Elizabeth Boath, Eleanor Bradley, Louise M Howard
BACKGROUND: Depression is common in the postnatal period and can lead to adverse effects on the infant and wider family, in addition to the morbidity for the mother. It is not clear whether antidepressants are effective for the prevention of postnatal depression and little is known about possible adverse effects for the mother and infant, particularly during breastfeeding. This is an update of a Cochrane Review last published in 2005. OBJECTIVES: To assess the effectiveness of antidepressant medication for the prevention of postnatal depression, in comparison with any other treatment, placebo or standard care...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29660598/first-in-human-phase-1-dose-escalation-pharmacokinetic-and-pharmacodynamic-study-of-the-oral-dual-pi3k-and-mtorc1-2-inhibitor-pqr309-in-patients-with-advanced-solid-tumors-sakk-67-13
#18
Andreas Wicki, Nicholas Brown, Alexandros Xyrafas, Vincent Bize, Hanne Hawle, Simona Berardi, Nataša Cmiljanović, Vladimir Cmiljanović, Michael Stumm, Saša Dimitrijević, Richard Herrmann, Vincent Prêtre, Reto Ritschard, Alexandar Tzankov, Viviane Hess, Alexa Childs, Cinta Hierro, Jordi Rodon, Dagmar Hess, Markus Joerger, Roger von Moos, Cristiana Sessa, Rebecca Kristeleit
BACKGROUND: PQR309 is an orally bioavailable, balanced pan-phosphatidylinositol-3-kinase (PI3K), mammalian target of rapamycin (mTOR) C1 and mTORC2 inhibitor. PATIENTS AND METHODS: This is an accelerated titration, 3 + 3 dose-escalation, open-label phase I trial of continuous once-daily (OD) PQR309 administration to evaluate the safety, pharmacokinetics (PK) and pharmacodynamics in patients with advanced solid tumours. Primary objectives were to determine the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D)...
June 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29596283/pediatric-sigmoid-volvulus
#19
Bennett Lee, Andrea Wu
Sigmoid volvulus is an extremely rare cause of abdominal pain in children. More commonly seen in older adults, an SV occurs when a redundant loop of sigmoid wraps around its elongated, narrow mesentery causing obstruction and ischemia to the affected bowel segment. Children usually present with abdominal pain, nausea, and abdominal distension. Presentations may be acute or chronic with a history of episodic constipation or abdominal distension. The treatment plan includes an initial reduction of the volvulus via sigmoidoscopy with rectal biopsy to rule out Hirschsprung disease; however, operative management to remove the dilated sigmoid colon may be required in the setting of recurrence or confirmed Hirschsprung disease...
March 28, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29596128/a-retrospective-study-comparing-polyethylene-glycol-electrolyte-solution-with-magnesium-citrate-for-treatment-of-fecal-disimpaction
#20
Lisa Philichi, Melawati Yuwono
Fecal disimpaction in the hospital setting may be necessary for a constipated child's condition to improve. This study evaluated the efficiency of 2 disimpaction therapies: nasogastric GoLYTELY (polyethylene glycol-electrolyte solution) compared with oral magnesium citrate. Retrospective chart review of 103 children was conducted to determine the time from the start of the clinic cleanout until abdominal radiograph verification of successful stool evacuation. The children were in an age range of 1-18 years, with average age of 8 years...
March 2018: Gastroenterology Nursing: the Official Journal of the Society of Gastroenterology Nurses and Associates
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