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https://www.readbyqxmd.com/read/28551896/-review-of-common-pathogens-in-the-bone-and-blood-cultures-and-antibiotic-treatment-in-patients-with-sternal-osteomyelitis
#1
Michal Benkler, Ori Shulman, Yoav Avrahamy, David Mendes, Yoav Arus, Ron Fishel, Amos Leviav, Dana Egozi
AIMS: This study concentrates on microbiological data collection of deep sternal wounds to delineate early and correct antibiotic therapy. BACKGROUND: Deep sternal wound infection, mediastinitis and sternal osteomyelitis are devastating and life-threatening complications of median-sternotomy incisions after cardiac surgical procedures. The incidence of surgical wound infection in sternotomies should be similar to that in any clean surgical procedure (i.e. approximately 2%)...
February 2017: Harefuah
https://www.readbyqxmd.com/read/28551887/bacteriological-safety-assessment-hygienic-habits-and-cross-contamination-risks-in-a-nigerian-urban-sample-of-household-kitchen-environment
#2
Bernard O Ejechi, Ono P Ochei
Urban household kitchen environment was assessed for safety by determining their levels of indicator bacteria, hygienic habits and risk of cross-contamination. Household kitchens (60) were selected in Warri Town, Nigeria, by the multi-stage sampling technique. Contact surfaces, water and indoor kitchen air were analysed for aerobic plate counts, total and faecal coliforms using Nutrient and McConkey media by swab/rinse method, membrane filtration and sedimentation methods, respectively. Hygienic habits and risk of cross-contamination were assessed with structured questionnaire which included socio-demographic variables...
June 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28551843/incidence-and-risk-factors-of-febrile-neutropenia-in-patients-with-non-hodgkin-b-cell-lymphoma-receiving-r-chop-in-a-single-center-in-japan
#3
Masahiro Yokoyama, Yoshiharu Kusano, Anna Takahashi, Norihito Inoue, Kyoko Ueda, Noriko Nishimura, Yuko Mishima, Yasuhito Terui, Tomoyuki Nukada, Takanobu Nomura, Kiyohiko Hatake
PURPOSE: The incidence of and risk factors for febrile neutropenia (FN) in Japanese non-Hodgkin B-cell lymphoma (B-NHL) patients receiving rituximab, cyclophosphamide, doxorubicin, vincristine, and predonisolone (R-CHOP) chemotherapy are unknown. We conducted this study to address this issue. METHODS: In this single-center, retrospective, observational study, 466 patients with B-NHL who completed an R-CHOP regimen within a 7-year period and who planned to undergo at least three cycles of this regimen were analyzed...
May 27, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28551712/extracardiac-imaging-of-infective-endocarditis
#4
REVIEW
Xavier Duval, Bernard Iung
PURPOSE OF REVIEW: This review analyzes recent studies evaluating the diagnostic and therapeutic impacts of systematic extracardiac imaging techniques in patients with suspected or proven infective endocarditis. RECENT FINDINGS: Extracardiac imaging techniques are more and more frequently used to establish infective endocarditis (IE) diagnosis in doubtful situations. They also help in evaluating the risk-benefit balance of therapeutic strategies and particularly valvular surgery which is performed in approximately 50% of patients...
July 2017: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/28551668/occupational-risk-for-oral-cancer-in-nordic-countries
#5
Laura Tarvainen, Juho Suojanen, Pentti Kyyronen, Christian Lindqvist, Jan Ivar Martinsen, Kristina Kjaerheim, Elsebeth Lynge, Par Sparen, Laufey Tryggvadottir, Elisabete Weiderpass, Eero Pukkala
AIM: To evaluate occupational risk for cancer of the tongue, oral cavity or pharynx after adjustment for alcohol and tobacco use. MATERIALS AND METHODS: The data covered 14.9 million people and 28,623 cases of cancer of the tongue, oral cavity and pharynx in the Nordic countries 1961-2005. Alcohol consumption by occupation was estimated based on mortality from liver cirrhosis and incidence of liver cancer. Smoking by occupation was estimated based on the incidence of lung cancer...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28551446/intimate-partner-violence-and-pregnancy-epidemiology-and-impact
#6
REVIEW
Christian A Chisholm, Linda Bullock, James E Jef Ferguson
Intimate partner violence (IPV) is a significant public health problem in our society, affecting women disproportionately. IPV takes many forms, including physical violence, sexual violence, stalking, and psychological aggression. While the scope of IPV is not fully documented, nearly 40% of women in the US are victims of sexual violence in their lifetimes and 20% are victims of physical IPV. Other forms of IPV are likely particularly underreported. IPV has a substantial impact on a woman's physical and mental health...
May 24, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28551372/clinical-course-and-perinatal-transmission-of-chronic-hepatitis-b-during-pregnancy-in-a-real-life-setting-a-prospective-cohort-study
#7
Zhi-Xian Chen, Gui-Fang Gu, Zhao-Lian Bian, Wei-Hua Cai, Yi Shen, Yan-Li Hao, Sheng Zhang, Jian-Guo Shao, Gang Qin
OBJECTIVE: To determine the clinical course and perinatal transmission of chronic hepatitis B during pregnancy in a real life setting. METHODS: A total of 221 singleton pregnant women with detectable HBV-DNA levels (≥ 10(3) copies/mL) were enrolled during January 2011 to June 2015. Forty-three high viraemic patients (≥ 10(6) copies/mL) received telbivudine in the 2(nd) or 3(rd) trimester according to their intention, while 89 high viraemic and 79 low viraemic (≥10(3)and <10(6) copies/mL) patients were the control cohorts...
May 24, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28551052/fresh-osteochondral-allotransplants-outcomes-failures-and-future-developments
#8
M Tschon, F Veronesi, S Giannini, M Fini
Osteochondral allografts are used to treat many different conditions as acute traumatic large-sized lesions, degenerative osteoarthritis, osteochondritis dissecans, avascular necrosis or in case of failure of previous procedures particularly in young patients for whom primary prosthesis is not desirable. Fresh allografts present the advantage of having mature viable hyaline cartilage, not causing donor morbidity, allowing the restoration of even large defects in a single surgical session. Conversely, they could account for risks of disease transmission, immunologic reactions, and for limited availability...
May 11, 2017: Injury
https://www.readbyqxmd.com/read/28550906/procalcitonin-and-white-blood-cells-combined-predictors-of-infection-in-cardiac-surgery-patients
#9
María Heredia-Rodríguez, Juan Bustamante-Munguira, Mario Lorenzo, Esther Gómez-Sánchez, F Javier Álvarez, Inmaculada Fierro, Esther Conejo, Eduardo Tamayo
BACKGROUND: Sepsis is strongly associated with an increased risk of postoperative mortality, longer length of hospital stay, and elevated health care costs. Early clinical symptoms overlap with those of systemic inflammatory response syndrome, a response that commonly occurs after cardiac surgery with cardiopulmonary bypass. Since a combination of biomarkers has been demonstrated to improve the prediction of postoperative infection, the objective of the present study was to test whether the combination of C-reactive protein (CRP), white blood cells (WBC), and procalcitonin (PCT) is able to predict postoperative infection in a large cohort of cardiac surgery patients...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28550816/designing-an-hcv-vaccine-a-unique-convergence-of-prevention-and-therapy
#10
REVIEW
Christopher M Walker
Direct acting antivirals can cure chronic hepatitis C virus (HCV) infection but whether they will reduce global liver disease burden is uncertain. Most chronic infections are undiagnosed and transmission has increased in recent years. The first trial of a preventive vaccine is now underway in humans at risk for HCV infection. It will test the novel hypothesis that T cell-mediated immunity alone can prevent persistent HCV infection. Another vaccine that elicits neutralizing antibodies is at an advanced stage of development...
May 24, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28550812/molecular-characterization-of-human-adenoviruses-in-urban-wastewaters-using-next-generation-and-sanger-sequencing
#11
M Iaconelli, B Valdazo-González, M Equestre, A R Ciccaglione, C Marcantonio, S Della Libera, G La Rosa
Human adenoviruses (HAdVs) are of major public health importance and are associated with a variety of clinical manifestations, including gastroenteritis, respiratory, ocular and urinary tract infections. To study the occurrence, prevalence and diversity of HAdV species and types circulating in Italy, we conducted a large-scale molecular-epidemiological investigation, a yearlong monitoring of 22 wastewater treatment plants, covering 10 Italian regions, representative of northern, central, and southern Italy...
May 19, 2017: Water Research
https://www.readbyqxmd.com/read/28550598/serum-ebv-ea-iga-and-vca-iga-antibodies-can-be-used-for-risk-group-stratification-and-prognostic-prediction-in-extranodal-nk-t-cell-lymphoma-24-year-experience-at-a-single-institution
#12
Yuhua Huang, Huilan Rao, Shumei Yan, Fang Wang, Qinian Wu, Yanfen Feng, Yujing Zhang
Although extranodal NK/T cell lymphoma (ENKTCL) is consistently associated with Epstein-Barr virus (EBV) infection, the manifestation and prognostic value of serum EBV antibodies still remain unknown. One hundred and forty-one patients with ENKTCL were evaluated for serum EBV EA-IgA and VCA-IgA antibodies levels in the past 24 years in our institution. Their correlation with clinicopathological features, plasma EBV DNA load, and patients' outcomes was analyzed. EBV EA-IgA ≥1:10 and VCA-IgA ≥1:160 were found in 18...
May 27, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/28550594/comparison-of-rapid-diagnostic-tests-to-detect-mycobacterium-avium-subsp-paratuberculosis-disseminated-infection-in-bovine-liver
#13
Mehdi Zarei, Masoud Ghorbanpour, Samaneh Tajbakhsh, Nader Mosavari
Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne's disease, a chronic enteritis in cattle and other domestic and wild ruminants. The presence of MAP in tissues other than intestines and associated lymph nodes, such as meat and liver, is a potential public health concern. In the present study, the relationship between the results of rapid diagnostic tests of the Johne's disease, such as serum ELISA, rectal scraping PCR, and acid-fast staining, and the presence of MAP in liver was evaluated. Blood, liver, and rectal scraping samples were collected from 200 slaughtered cattle with unknown Johne's disease status...
May 27, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28550428/partial-component-retained-two-stage-reconstruction-for-chronic-infection-after-uncemented-total-hip-arthroplasty-results-of-sixteen-cases-after-five-years-of-follow-up
#14
Kun-Hui Chen, Shang-Wen Tsai, Po-Kuei Wu, Cheng-Fong Chen, Hsin-Yi Wang, Wei-Ming Chen
PURPOSE: Two-stage reconstruction with total implant removal and re-implantation after infection control is considered the gold standard treatment for infection after hip arthroplasty. However, removal of the well-fixed stem or cup may cause substantial bone loss and other complications, thereby making reconstruction difficult. We evaluated whether an infection post total hip arthroplasty can be treated without removal of the radiographically and clinically well-fixed femoral stem or acetabular cup...
May 27, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28550378/longitudinal-modeling-of-depressive-trajectories-among-hiv-infected-men-using-cocaine
#15
Shibani Mukerji, Roxanna Haghighat, Vikas Misra, David R Lorenz, Alex Holman, Anupriya Dutta, Dana Gabuzda
Cocaine use is prevalent among HIV-infected individuals. While cross-sectional studies suggest that cocaine users may be at increased risk for depression, long-term effects of cocaine on depressive symptoms remain unclear. This is a longitudinal study of 341 HIV-infected and uninfected men (135 cocaine users and 206 controls) ages 30-60 enrolled in the Multicenter AIDS Cohort Study during 1996-2009. The median baseline age was 41; 73% were African-American. In mixed-effects models over a median of 4.8 years of observation, cocaine use was associated with higher depressive symptoms independent of age, education level, and smoking (n = 288; p = 0...
May 26, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28550341/development-of-a-risk-algorithm-to-better-target-sti-testing-and-treatment-among-australian-aboriginal-and-torres-strait-islander-people
#16
Handan Wand, Joanne Bryant, Marian Pitts, Dea Delaney-Thiele, John M Kaldor, Heather Worth, James Ward
Identifying and targeting those at greatest risk will likely play a significant role in developing the most efficient and cost-effective sexually transmissible infections (STI) prevention programs. We aimed to develop a risk prediction algorithm to identify those who are at increased risk of STI. A cohort (N = 2320) of young sexually active Aboriginal and Torres Strait Islander people (hereafter referred to as Aboriginal people) were included in this study. The primary outcomes were self-reported high-risk sexual behaviors and past STI diagnosis...
May 26, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28550059/europe-wide-meta-analysis-of-borrelia-burgdorferi-sensu-lato-prevalence-in-questing-ixodes-ricinus-ticks
#17
Martin Strnad, Václav Hönig, Daniel Růžek, Libor Grubhoffer, Ryan O M Rego
Lyme borreliosis is the most common zoonotic disease transmitted by ticks in Europe and North America. Despite having multiple tick vectors, the causative agent Borrelia burgdorferi sensu lato, is vectored mainly by Ixodes ricinus in Europe. In the present study, we aimed to review and summarize the existing data published from 2010 to 2016 concerning the prevalence of B. burgdorferi s.l. spirochetes in questing I. ricinus The primary focus was to evaluate the infection rate of these bacteria in ticks, accounting for tick stage, adult tick gender, region and detection method, as well as to investigate any changes in prevalence over time...
May 26, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28549881/health-problems-and-disinfectant-product-exposure-among-staff-at-a-large-multispecialty-hospital
#18
Megan L Casey, Brie Hawley, Nicole Edwards, Jean M Cox-Ganser, Kristin J Cummings
BACKGROUND: Hospital staff expressed health concerns after a surface disinfectant product containing hydrogen peroxide, peracetic acid, and acetic acid was introduced. We sought to determine if this product posed a health hazard. METHODS: An interviewer-administered questionnaire on work and health characteristics was completed by 163 current staff. Symptoms that improved away from work were considered work-related. Forty-nine air samples were taken for hydrogen peroxide, peracetic acid, and acetic acid...
May 23, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28549880/risk-factors-for-health-care-associated-infections-from-better-knowledge-to-better-prevention
#19
Etelvina Ferreira, Elaine Pina, Mafalda Sousa-Uva, António Sousa-Uva
BACKGROUND: Health care-associated infections (HCAIs) are preventable with adoption of recognized preventive measures. The first step is to identify patients at higher risk of HCAI. This study aimed to identify patient risk factors (RFs) present on admission and acquired during inpatient stay which could be associated with higher risk of acquiring HCAI. METHODS: A case-control study was conducted in adult patients admitted during 2011 who were hospitalized for >48 hours...
May 23, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28549856/three-decades-of-managing-tomato-spotted-wilt-virus-in-peanut-in-southeastern-united-states
#20
REVIEW
R Srinivasan, M R Abney, A K Culbreath, R C Kemerait, R S Tubbs, W S Monfort, H R Pappu
Southeastern states namely Georgia, Florida, and Alabama produce two-thirds of the peanuts in the United States. Thrips-transmitted Tomato spotted wilt virus (TSWV), which causes spotted wilt disease, has been a major impediment to peanut production for the past three decades. The cultivars grown in the 1980s were extremely susceptible to TSWV. Early yield losses extended to tens of millions of dollars each year (up to 100% loss in many fields). This situation led to the creation of an interdisciplinary team known as "SWAT: Spotted Wilt Action Team"...
May 23, 2017: Virus Research
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