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https://www.readbyqxmd.com/read/28223090/roux-en-y-gastric-bypass-for-the-treatment-of-severe-complications-after-omega-loop-gastric-bypass
#1
Tigran Poghosyan, Clementine Caille, David Moszkowicz, Mouna Hanachi, Claire Carette, Jean-Luc Bouillot
BACKGROUND: Omega-loop gastric bypass (OLGB) may be associated with severe complications, including anastomotic leak, refractory ulcer or stenosis, undernutrition, and disabling digestive disorders (chronic diarrhea, steatorrhea, bile reflux, and vomiting). OLGB conversion to Roux-en-Y gastric bypass (RYGB) was suggested to treat these complications. OBJECTIVES: To evaluate the efficacy and risk of severe complications after OLGB conversion to RYGB. SETTING: University hospital...
December 9, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28221817/neuroprotective-effect-of-omega-3-polyunsaturated-fatty-acids-in-the-6-ohda-model-of-parkinson-s-disease-is-mediated-by-a-reduction-of-inducible-nitric-oxide-synthase
#2
Marco Aurélio Mori, Ana Marcia Delattre, Bruno Carabelli, Claudia Pudell, Mariza Bortolanza, Pedro Vinícius Staziaki, Jesuí Vergilio Visentainer, Paula Fernandes Montanher, Elaine A Del Bel, Anete Curte Ferraz
OBJECTIVE: Parkinson's disease (PD) is characterized by deterioration of the nigrostriatal system and associated with chronic neuroinflammation. Glial activation has been associated with regulating the survival of dopaminergic neurons and is thought to contribute to PD through the release of proinflammatory and neurotoxic factors, such as reactive nitric oxide (NO) that triggers or exacerbates neurodegeneration in PD. Polyunsaturated fatty acids (PUFAs) exert protective effects, including antiinflammatory, antiapoptotic, and antioxidant activity, and may be promising for delaying or preventing PD by attenuating neuroinflammation and preserving dopaminergic neurons...
February 21, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28219837/chronic-maternal-calcium-and-25-hydroxyvitamin-d-deficiency-in-wistar-rats-programs-abnormal-hepatic-gene-expression-leading-to-hepatic-steatosis-in-female-offspring
#3
Sona S Sharma, Nivedita M Jangale, Abhay M Harsulkar, Medha K Gokhale, Bimba N Joshi
Importance of calcium and vitamin D deficiency is well established in adult dyslipidemia. We hypothesized that maternal calcium and vitamin D deficiency could alter offspring's lipid metabolism. Our objective was to investigate the effect of maternal dietary calcium and vitamin D deficiency on lipid metabolism and liver function of the F1 generation offspring. intergenerational calcium-deficient (CaD) and vitamin D-deficient (VDD) models were developed by mating normal male rats with deficient females and continuing maternal-deficient diets through pregnancy and lactation...
February 8, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28218722/relationship-between-long-chain-n-3-polyunsaturated-fatty-acids-and-autism-spectrum-disorder-systematic-review-and-meta-analysis-of-case-control-and-randomised-controlled-trials
#4
REVIEW
Hajar Mazahery, Welma Stonehouse, Maryam Delshad, Marlena C Kruger, Cathryn A Conlon, Kathryn L Beck, Pamela R von Hurst
Omega-3 long chain polyunsaturated fatty acid supplementation (n-3 LCPUFA) for treatment of Autism Spectrum Disorder (ASD) is popular. The results of previous systematic reviews and meta-analyses of n-3 LCPUFA supplementation on ASD outcomes were inconclusive. Two meta-analyses were conducted; meta-analysis 1 compared blood levels of LCPUFA and their ratios arachidonic acid (ARA) to docosahexaenoic acid (DHA), ARA to eicosapentaenoic acid (EPA), or total n-6 to total n-3 LCPUFA in ASD to those of typically developing individuals (with no neurodevelopmental disorders), and meta-analysis 2 compared the effects of n-3 LCPUFA supplementation to placebo on symptoms of ASD...
February 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28218036/chemopreventive-effect-of-omega-3-polyunsaturated-fatty-acids-and-atorvastatin-in-rats-with-bladder-cancer
#5
Nahla E El-Ashmawy, Eman G Khedr, Hoda A El-Bahrawy, Samar M Al-Tantawy
Bladder cancer remains a huge concern for the medical community because of its incidence and prevalence rates, as well as high percentage of recurrence and progression. Omega-3 polyunsaturated fatty acids and atorvastatin proved anti-inflammatory effects through peroxisome proliferator-activated receptor gamma mechanism. However, their chemopreventive effect still remained to be examined and clarified. In this study, bladder cancer was induced in rats by the chemical carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine...
February 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28214693/genomic-prediction-for-beef-fatty-acid-profile-in-nellore-cattle
#6
Hermenegildo Lucas Justino Chiaia, Elisa Peripoli, Rafael Medeiros de Oliveira Silva, Carolyn Aboujaoude, Fabiele Loise Braga Feitosa, Marcos Vinicius Antunes de Lemos, Mariana Piatto Berton, Bianca Ferreira Olivieri, Rafael Espigolan, Rafael Lara Tonussi, Daniel Gustavo Mansan Gordo, Tiago Bresolin, Ana Fabrícia Braga Magalhães, Gerardo Alves Fernandes Júnior, Lúcia Galvão de Albuquerque, Henrique Nunes de Oliveira, Joyce de Jesus Mangini Furlan, Adrielle Mathias Ferrinho, Lenise Freitas Mueller, Humberto Tonhati, Angélica Simone Cravo Pereira, Fernando Baldi
The objective of this study was to compare SNP-BLUP, BayesCπ, BayesC and Bayesian Lasso methodologies to predict the direct genomic value for saturated, monounsaturated, and polyunsaturated fatty acid profile, omega 3 and 6 in the Longissimus thoracis muscle of Nellore cattle finished in feedlot. A total of 963 Nellore bulls with phenotype for fatty acid profiles, were genotyped using the Illumina BovineHD BeadChip (Illumina, San Diego, CA) with 777,962 SNP. The predictive ability was evaluated using cross validation...
February 9, 2017: Meat Science
https://www.readbyqxmd.com/read/28213750/effect-of-an-acute-dose-of-omega-3-fish-oil-following-exercise-induced-muscle-damage
#7
J R Jakeman, D M Lambrick, B Wooley, J A Babraj, J A Faulkner
PURPOSE: The purpose of this double-blind, placebo-controlled study was to examine the effect of two fish oil supplements, one high in EPA (750 mg EPA, 50 mg DHA) and one low in EPA (150 mg EPA, 100 mg DHA), taken acutely as a recovery strategy following EIMD. METHODS: Twenty-seven physically active males (26 ± 4 year, 1.77 ± 0.07 m, 80 ± 10 kg) completed 100 plyometric drop jumps to induce muscle damage. Perceptual (perceived soreness) and functional (isokinetic muscle strength at 60° and 180° s(-1), squat jump performance and countermovement jump performance) indices of EIMD were recorded before, and 1, 24, 48, 72, and 96h after the damaging protocol...
February 17, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28212390/lack-of-effects-of-fish-oil-supplementation-for-12-weeks-on-resting-metabolic-rate-and-substrate-oxidation-in-healthy-young-men-a-randomized-controlled-trial
#8
Sebastian Jannas-Vela, Kaitlin Roke, Stephanie Boville, David M Mutch, Lawrence L Spriet
: Fish oil (FO) has been shown to have beneficial effects in the body via incorporation into the membranes of many tissues. It has been proposed that omega-3 fatty acids in FO may increase whole body resting metabolic rate (RMR) and fatty acid (FA) oxidation in human subjects, but the results to date are equivocal. The purpose of this study was to investigate the effects of a 12 week FO supplementation period on RMR and substrate oxidation, in comparison to an olive oil (OO) control group, in young healthy males (n = 26; 22...
2017: PloS One
https://www.readbyqxmd.com/read/28209162/fatty-acid-and-cholesterol-profiles-hypocholesterolemic-atherogenic-and-thrombogenic-indices-of-broiler-meat-in-the-retail-market
#9
Youssef A Attia, Mohammed A Al-Harthi, Mohamed A Korish, Mohamed M Shiboob
BACKGROUND: Broiler meat is an essential source of food due to its favourable effects on human health derived from its protein, fats, minerals, vitamins and its bioactive components. METHODS: A total of 90 carcasses were collected from the retail market in Jeddah city, Saudi Arabia during April, May and June 2014 to determine the effects of meat type (frozen vs. fresh) and sources within fresh types (A, B, C) vs. frozen types (D, E and F) on their fatty acid profiles, cholesterol, their hypocholesterolemic, atherogenic and thrombogenic indices, and on their antioxidants' status...
February 16, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28192066/performance-of-debaryomyces-hansenii-as-a-diet-for-rotifers-for-feeding-zebrafish-larvae
#10
Rafael Opazo, Karen Fuenzalida, Francisca Plaza-Parrochia, Jaime Romero
The zebrafish larval stage is a critical moment due to high mortality rates associated with inadequate supplies of nutritional requirements. Larval feeding has important challenges associated with such factors as small mouth gape (≈100 μm), the low activity of digestive enzymes, and the intake of live food. A common zebrafish live food at the onset of exogenous feeding is rotifers, mainly Brachionus plicatilis. These rotifers should be fed with other microorganisms such as microalgae or yeast, mostly from the Saccharomyces genus...
February 13, 2017: Zebrafish
https://www.readbyqxmd.com/read/28189073/lower-levels-of-persistent-organic-pollutants-metals-and-the-marine-omega-3-fatty-acid-dha-in-farmed-compared-to-wild-atlantic-salmon-salmo-salar
#11
Anne-Katrine Lundebye, Erik-Jan Lock, Josef D Rasinger, Ole Jakob Nøstbakken, Rita Hannisdal, Egil Karlsbakk, Vidar Wennevik, Abdullah S Madhun, Lise Madsen, Ingvild Eide Graff, Robin Ørnsrud
Contaminants and fatty acid levels in farmed- versus wild Atlantic salmon have been a hot topic of debate in terms of food safety. The present study determined dioxins (polychlorinated dibenzo-p-dioxin and dibenzofuran), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), organochlorine pesticides (OCPs), metals and fatty acids in wild and farmed Atlantic salmon. Contaminant levels of dioxins, PCBs, OCPs (DDT, dieldrin, lindane, chlordane, Mirex, and toxaphene), and mercury were higher in wild salmon than in farmed salmon, as were the concentrations of the essential elements selenium, copper, zinc and iron, and the marine omega-3 fatty acid docosahexaenoic acid (DHA)...
February 8, 2017: Environmental Research
https://www.readbyqxmd.com/read/28185444/effect-of-cis-palmitoleic-acid-an-omega-7-fatty-acid-supplementation-on-inflammation-and-expression-of-hnf4%C3%AE-hnf4%C3%AE-and-il-6-in-patients-with-ulcerative-colitis-a-double-blind-randomized-pilot-study
#12
Nalley Bueno-Hernandez, Maria S Sixtos-Alonso, Maria Del Pilar Milke GARCíA, Jesus K Yamamoto-Furusho
BACKGROUND: Cis-palmitoleic acid (Omega-7 fatty acid) is a monounsaturated fatty acid (MUFA) associated with anti-inflammatory process through specific protein interactions such as HNF4γ and HNF4α, these two genes are related to the immune response in ulcerative colitis (UC) they may act as a mediator of anti- inflammatory action. The aim of this study was to evaluate the effect of Cis- palmitoleic acid supplementation on inflammatory activity and the expression of genes HNF4γ, HNF4α and IL-6 in the colonic mucosa of patients with active UC...
February 9, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28183443/improvement-of-the-omega-3-index-of-healthy-subjects-does-not-alter-the-effects-of-dietary-saturated-fats-or-n-6pufa-on-ldl-profiles
#13
Cintia B Dias, Núria Amigó, Lisa G Wood, Roger Mallol, Xavier Correig, Manohar L Garg
BACKGROUND AND AIMS: Dietary fat composition is known to modulate circulating lipid and lipoprotein levels. Although supplementation with long chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) has been shown to reduce plasma triglyceride levels, the effect of the interactions between LCn-3PUFA and the major dietary fats consumed has not been previously investigated. METHODS: In a randomized controlled parallel design clinical intervention, we examined the effect of diets rich in either saturated fatty acids (SFA) or omega-6 polyunsaturated fatty acids (n-6PUFA) on plasma lipid levels and lipoprotein profiles (lipoprotein size, concentration and distribution in subclasses) in subjects with an adequate omega 3 index...
March 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28183205/inhibition-of-rho-kinase-protects-from-ischaemia-reperfusion-injury-via-regulation-of-arginase-activity-and-nitric-oxide-synthase-in-type-1-diabetes
#14
Yahor Tratsiakovich, Attila Kiss, Adrian T Gonon, Jiangning Yang, Per-Ove Sjöquist, John Pernow
AIM: RhoA/Rho-associated kinase and arginase are implicated in vascular complications in diabetes. This study investigated whether RhoA/Rho-associated kinase and arginase inhibition protect from myocardial ischaemia-reperfusion injury in type 1 diabetes and the mechanisms behind these effects. METHODS: Rats with streptozotocin-induced type 1 diabetes and non-diabetic rats were subjected to 30 min myocardial ischaemia and 2 h reperfusion after being randomized to treatment with (1) saline, (2) RhoA/Rho-associated kinase inhibitor hydroxyfasudil, (3) nitric oxide synthase inhibitor N(G)-monomethyl-l-arginine monoacetate followed by hydroxyfasudil, (4) arginase inhibitor N-omega-hydroxy-nor-l-arginine, (5) N(G)-monomethyl-l-arginine monoacetate followed by N-omega-hydroxy-nor-l-arginine or (6) N(G)-monomethyl-l-arginine monoacetate given intravenous before ischaemia...
February 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28177133/dietary-supplementation-with-low-dose-omega-3-fatty-acids-reduces-salivary-tumor-necrosis-factor-%C3%AE-levels-in-patients-with-chronic-periodontitis-a-randomized-controlled-clinical-study
#15
I Keskiner, I Saygun, V Bal, M Serdar, A Kantarci
BACKGROUND AND OBJECTIVE: Recent studies have demonstrated the beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) on physiological processes and on a variety of chronic inflammatory diseases, including periodontal diseases. In this study, we evaluated the impact of omega-3 PUFAs in conjunction with scaling and root planing (SRP) on salivary markers in patients with chronic periodontitis. MATERIAL AND METHODS: Thirty systemically healthy subjects with chronic periodontitis were enrolled and randomly allocated into two groups...
February 8, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28173875/restored-in-vivo-like-membrane-lipidomics-positively-influence-in-vitro-features-of-cultured-mesenchymal-stromal-stem-cells-derived-from-human-placenta
#16
Alexandros Chatgilialoglu, Martina Rossi, Francesco Alviano, Paola Poggi, Chiara Zannini, Cosetta Marchionni, Francesca Ricci, Pier Luigi Tazzari, Valentina Taglioli, Philip C Calder, Laura Bonsi
BACKGROUND: The study of lipid metabolism in stem cell physiology has recently raised great interest. The role of lipids goes beyond the mere structural involvement in assembling extra- and intra-cellular compartments. Nevertheless, we are still far from understanding the impact of membrane lipidomics in stemness maintenance and differentiation patterns. In the last years, it has been reported how in vitro cell culturing can modify membrane lipidomics. The aim of the present work was to study the membrane fatty acid profile of mesenchymal stromal cells (MSCs) derived from human fetal membranes (hFM-MSCs) and to correlate this to specific biological properties by using chemically defined tailored lipid supplements (Refeed®)...
February 7, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28170420/sustainable-production-of-housefly-musca-domestica-larvae-as-a-protein-rich-feed-ingredient-by-utilizing-cattle-manure
#17
Mahmoud Hussein, Viju V Pillai, Joshua M Goddard, Hui G Park, Kumar S Kothapalli, Deborah A Ross, Quirine M Ketterings, J Thomas Brenna, Mark B Milstein, Helene Marquis, Patricia A Johnson, Jan P Nyrop, Vimal Selvaraj
The common housefly, Musca domestica, is a considerable component of nutrient recycling in the environment. Use of housefly larvae to biodegrade manure presents an opportunity to reduce waste disposal while the rapidly assimilated insect biomass can also be used as a protein rich animal feed. In this study, we examine the biodegradation of dairy cattle manure using housefly larvae, and the nutritional value of the resulting larva meal as a feed ingredient. Our results demonstrated that dairy cattle manure presents a balanced substrate for larval growth, and the spent manure showed reductions in concentration of total nitrogen (24...
2017: PloS One
https://www.readbyqxmd.com/read/28169288/omega-3-and-omega-6-dpa-equally-inhibit-the-sphingosylphosphorylcholine-induced-ca-2-sensitization-of-vascular-smooth-muscle-contraction-via-inhibiting-rho-kinase-activation-and-translocation
#18
Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Sei Kobayashi
We previously reported that eicosapentaenoic acid (EPA), an omega-3 polyunsaturated fatty acid (n-3 PUFA), effectively inhibits sphingosylphosphorylcholine (SPC)-induced Ca(2+)-sensitization of vascular smooth muscle (VSM) contraction which is a major cause of cardiovascular and cerebrovascular vasospasm, and EPA is utilized clinically to prevent cerebrovascular vasospasm. In this study, we clearly demonstrate that docosapentaenoic acid (DPA), which exists in two forms as omega-3 (n-3) and omega-6 (n-6) PUFA, strongly inhibits SPC-induced contraction in VSM tissue and human coronary artery smooth muscle cells (CASMCs), with little effect on Ca(2+)-dependent contraction...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28167220/omega-3-fatty-acids-and-cytochrome-p450-derived-eicosanoids-in-cardiovascular-diseases-which-actions-and-interactions-modulate-hemodynamics
#19
REVIEW
Sara Bonafini, Cristiano Fava
Increasing interest is focused on omega-3 fatty acids (FA) because of their potential beneficial effects, particularly in cardiovascular disease prevention. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), two major omega-3 FA, are mainly consumed through diet, particularly from fish and seafood intake, whereas alpha-linolenic acid (ALA) is present in high amounts in leafy green vegetables, nuts and seeds. The hypothesis of a cardiovascular protective action of omega-3 FA derives mainly from observational studies, whereas the evidence from interventional studies is not always consistent...
February 3, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28166924/-lifestyle-recommendations-for-prevention-of-spontaneous-preterm-birth-in-asymptomatic-pregnant-women
#20
E Maisonneuve
OBJECTIVES: To establish recommendations for lifestyle of pregnant women and its impact on spontaneous preterm births. MATERIAL AND METHODS: We searched Pubmed and Cochrane databases and checked reference lists of retrieved studies. This review of the literature concerns only women who have no symptoms for the ongoing pregnancy. RESULTS: Concerning maternal occupation during pregnancy, there is a mild increase of the risk of preterm birth only for women who work more than 40hours a week or who have hard working conditions according to a fatigue score (LE2)...
December 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
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