keyword
MENU ▼
Read by QxMD icon Read
search

Assis d

keyword
https://www.readbyqxmd.com/read/29665644/biodistribution-of-free-and-encapsulated-99m-tc-fluconazole-in-an-infection-model-induced-by-candida-albicans
#1
Danielle Nogueira de Assis, Raquel Silva Araújo, Leonardo Lima Fuscaldi, Simone Odília Antunes Fernandes, Vanessa Carla Furtado Mosqueira, Valbert Nascimento Cardoso
BACKGROUND: Candida spp is an etiologic agent of fungal infections in hospitals and resistance to treatment with antifungals has been extensively reported. Thus, it is very important to develop formulations that increase effectiveness with low toxicity. In this sense, nanocarriers have been investigated, once they modify drug biodistribution profile. Thus, this study aimed to evaluate the biodistribution of free and encapsulated 99m Tc-fluconazole into nanocapsules (NCs) in an experimental immunosuppressed murine model of Candida albicans infection...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29659165/improving-academic-performance-of-sport-and-exercise-science-undergraduate-students-in-gross-anatomy-using-a-near-peer-teaching-program
#2
Ricardo Borges Viana, Mário Hebling Campos, Douglas de Assis Teles Santos, Isabela Cristina Maioni Xavier, Rodrigo Luiz Vancini, Marília Santos Andrade, Claudio Andre Barbosa de Lira
Peer and near-peer teaching programs are common in medical undergraduate courses. However, there are no studies that have investigated the effectiveness of a near-peer teaching program on the academic performance of undergraduate students pursuing sport and exercise science coursework. This study was conducted to analyze the effectiveness of such a program for students who participated in a course on the functional anatomy of the locomotor apparatus. A total of 39 student participants were divided into two groups: students in one group voluntarily attended at least one session of a near-peer teaching program, and students in the other group attended no sessions...
April 16, 2018: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29621603/type-c-botulism-in-domestic-chickens-dogs-and-black-pencilled-marmoset-callithrix-penicillata-in-minas-gerais-brazil
#3
Rodrigo Otávio Silveira Silva, Ronaldo Alves Martins, Ronnie Antunes Assis, Carlos Augusto Oliveira Junior, Francisco Carlos Faria Lobato
Botulism is a well-known intoxication that affects humans and animals. The disease is endemic in cattle in Brazil and recently emerged as an important disease in commercial laying hens and broiler chickens in Europe. Dogs and other animal species can also be affected. Although antitoxins are commonly administered to humans diagnosed with botulism, in animals this is rarely the case and the treatment of botulism is still based only on support therapy. In the present work, we report an outbreak of type C botulism in Brazil that simultaneously affected domestic chickens, dogs and a black-pencilled marmoset (Callithrix penicillata)...
April 2, 2018: Anaerobe
https://www.readbyqxmd.com/read/29569995/phosphorylation-and-interactions-associated-with-the-control-of-the-leishmania-poly-a-binding-protein-1-pabp1-function-during-translation-initiation
#4
Osvaldo P de Melo Neto, Tamara D C da Costa Lima, Kleison C Merlo, Tatiany P Romão, Pollyanna O Rocha, Ludmila A Assis, Larissa M Nascimento, Camila C Xavier, Antonio M Rezende, Christian R S Reis, Barbara Papadopoulou
The Poly-A Binding Protein (PABP) is a conserved eukaryotic polypeptide involved in many aspects of mRNA metabolism. During translation initiation, PABP interacts with the translation initiation complex eIF4F and enhances the translation of polyadenylated mRNAs. Schematically, most PABPs can be divided into an N-terminal RNA-binding region, a non-conserved linker segment and the C-terminal MLLE domain. In pathogenic Leishmania protozoans, three PABP homologues have been identified, with the first one (PABP1) targeted by phosphorylation and shown to co-immunoprecipitate with an eIF4F-like complex (EIF4E4/EIF4G3) implicated in translation initiation...
March 23, 2018: RNA Biology
https://www.readbyqxmd.com/read/29521677/biomechanical-behavior-of-tooth-implant-supported-prostheses-with-different-implant-connections-a-nonlinear-finite-element-analysis
#5
Gustavo Assis de Paula, Guilherme Carvalho Silva, Ênio Lacerda Vilaça, Tulimar Machado Cornacchia, Cláudia Silami de Magalhães, Allyson Nogueira Moreira
PURPOSE: Biomechanical behavior of tooth-implant-supported prostheses (TISPs) with external and internal implants was compared. MATERIALS AND METHODS: Two 3-D models of TISP were designed by varying the implant: external (Model EH) and internal hexagons (Model IH). After loading, von Mises stresses were obtained in implants, abutments, and screws. Principal maximum (σmax) and minimum (σmin) stresses were analyzed in periodontal ligament (PL), alveolar bone, and periimplant bone...
March 7, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29514597/dealing-with-missing-standard-deviation-and-mean-values-in-meta-analysis-of-continuous-outcomes-a-systematic-review
#6
Christopher J Weir, Isabella Butcher, Valentina Assi, Stephanie C Lewis, Gordon D Murray, Peter Langhorne, Marian C Brady
BACKGROUND: Rigorous, informative meta-analyses rely on availability of appropriate summary statistics or individual participant data. For continuous outcomes, especially those with naturally skewed distributions, summary information on the mean or variability often goes unreported. While full reporting of original trial data is the ideal, we sought to identify methods for handling unreported mean or variability summary statistics in meta-analysis. METHODS: We undertook two systematic literature reviews to identify methodological approaches used to deal with missing mean or variability summary statistics...
March 7, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29512479/evaluation-of-malaria-urban-risk-using-an-immuno-epidemiological-biomarker-of-human-exposure-to-anopheles-bites
#7
Dipomin F Traoré, André B Sagna, Akré M Adja, Dounin D Zoh, Kouassi N Lingué, Issa Coulibaly, Bertin N'Cho Tchiekoi, Serge B Assi, Anne Poinsignon, Mamadou Dagnogo, Franck Remoue
Urban malaria is an underestimated serious health concern in African countries. This study aimed to evaluate the risk of malaria transmission in an urban area by evaluating the level of human exposure to Anopheles bites using an Anopheles salivary biomarker ( gambiae Salivary Gland Protein-6 peptide 1 [gSG6-P1] peptide). Two multidisciplinary cross-sectional studies were undertaken in five sites of Bouaké city (three urban districts and two surrounding villages, used as control; Côte d'Ivoire) during the rainy season and the dry season...
March 5, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29497304/insulin-treatment-reverses-the-increase-in-atrogin-1-expression-in-atrophied-skeletal-muscles-of-diabetic-rats-with-acute-joint-inflammation
#8
Clara Maria Pinheiro-Dardis, Vânia Ortega Gutierres, Renata Pires Assis, Sabrina Messa Peviani, Gabriel Borges Delfino, João Luiz Quagliotti Durigan, Tania de Fátima Salvini, Amanda Martins Baviera, Iguatemy Lourenço Brunetti
Background: The aim of this study was to evaluate the changes in biomarkers of skeletal muscle proteolysis (atrogin-1, muscle RING finger-1 protein [MuRF-1]) and inflammation (nuclear factor kappa-B) in skeletal muscles of rats under two catabolic conditions, diabetes mellitus (DM) and acute joint inflammation, and the effects of insulin therapy. Materials and methods: Male Wistar rats were divided into groups without diabetes - normal (N), saline (NS), or ι-carrageenan (NCa) injection into the tibiotarsal joint - and groups with diabetes - diabetes (D), plus insulin (DI), saline (DS), or ι-carrageenan (DCa) injection into the tibiotarsal joint, or ι-carrageenan injection and treatment with insulin (DCaI)...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29485675/postpartum-bonding-difficulties-and-adult-attachment-styles-the-mediating-role-of-postpartum-depression-and-childbirth-related-ptsd
#9
Ilana S Hairston, Jonathan E Handelzalts, Chen Assis, Michal Kovo
Despite decades of research demonstrating the role of adult attachment styles and early mother-infant bonding in parenting behaviors and maternal mental health, these constructs have seldom been studied together. The present study aimed to investigate the relationship between attachment styles and specific bonding difficulties of mothers. In addition, as postpartum depression and childbirth-related posttraumatic stress symptoms have been associated with both constructs, we explored their possible mediation effect...
March 2018: Infant Mental Health Journal
https://www.readbyqxmd.com/read/29466761/nkp46-receptor-mediated-interferon-%C3%AE-production-by-natural-killer-cells-increases-fibronectin-1-to-alter-tumor-architecture-and-control-metastasis
#10
Ariella Glasner, Assi Levi, Jonatan Enk, Batya Isaacson, Sergey Viukov, Shari Orlanski, Alon Scope, Tzahi Neuman, Claes D Enk, Jacob H Hanna, Veronika Sexl, Stipan Jonjic, Barbara Seliger, Laurence Zitvogel, Ofer Mandelboim
No abstract text is available yet for this article.
February 20, 2018: Immunity
https://www.readbyqxmd.com/read/29463055/antibiotic-resistance-genetic-markers-and-integrons-in-white-soft-cheese-aspects-of-clinical-resistome-and-potentiality-of-horizontal-gene-transfer
#11
Ana Caroline L de Paula, Julliane D Medeiros, Analice C de Azevedo, Jéssica M de Assis Chagas, Vânia L da Silva, Cláudio G Diniz
Antibiotic resistance poses an important threat to global public health and has become a challenge to modern medicine. The occurrence of antibiotic-resistant bacteria in a broad range of foods has led to a growing concern about the impact that food may have as a reservoir of antibiotic resistance genes. Considering Minas Frescal Cheese (MFC)-a typical Brazilian white soft cheese-and its economic and cultural values, in this study, medically relevant antimicrobial-resistance genetic markers (AR genes) were screened, and the occurrence of integrons were evaluated in manufactured MFC using culture-independent approaches...
February 19, 2018: Genes
https://www.readbyqxmd.com/read/29446255/potential-genetic-markers-for-nonsyndromic-oral-clefts-in-the-brazilian-population-a-systematic-review-and-meta-analysis
#12
REVIEW
Renato Assis Machado, Isabela Porto de Toledo, Hercilio Martelli-Júnior, Silvia Regina Reis, Eliete Neves Silva Guerra, Ricardo D Coletta
BACKGROUND: Although various genes and genomic regions were described as of susceptibility for nonsyndromic oral clefts (NOC), recent reports have demonstrated significant interethnic variations in the genetic predisposition, a situation that affects the Brazilian population, one of the most admixed populations in the world. Therefore, the purpose of this review was to describe the available information on genetic risk markers for NOC in the Brazilian population. METHODS: A systematic search of the literature was performed using LILACS, LIVIVO, PubMed, Scopus, and Web of Science databases, and studies that investigated genetic susceptibility markers for NOC in the Brazilian population were retrieved...
February 15, 2018: Birth Defects Research
https://www.readbyqxmd.com/read/29430628/association-between-golgb1-tag-polymorphisms-and-nonsyndromic-cleft-palate-only-in-the-brazilian-population
#13
Renato Assis Machado, Hercílio Martelli-Júnior, Silvia Regina de Almeida Reis, Darlene Camati Persuhn, Ricardo D Coletta
Nonsyndromic oral clefts are common congenital birth defects that exhibit variable prevalence around the world, often influenced by population-dependent genetic predisposition. Few studies have been performed with nonsyndromic cleft palate only (NSCPO), limiting the knowledge of the genetic risk factors related to this type of oral cleft. Genetic variants in golgin subfamily B member 1 (GOLGB1), a gene that is essential for normal murine palatogenesis, were analyzed in this study to establish its potential association with NSCPO risk in the Brazilian population...
February 12, 2018: Annals of Human Genetics
https://www.readbyqxmd.com/read/29427274/genotoxicity-of-spent-pot-liner-as-determined-with-the-zebrafish-danio-rerio-experimental-model
#14
Tássia F D Castro, Isadora M Paiva, Aline F S Carvalho, Isadora L Assis, Marcel J Palmieri, Larissa F Andrade-Vieira, Silvana Marcussi, Luis D Solis-Murgas
Spent pot liner (SPL) is a solid waste generated during the primary smelting of aluminum, and its toxicity is attributed to the presence of fluoride, cyanide, and aluminum salts, which can be leached into aquatic ecosystems. Since the effects of this waste on aquatic life forms have not yet been investigated, the objective of our study was to evaluate the toxicity of simulated leachates of SPL on zebrafish (Danio rerio). Animals were exposed to 0 (control), 0.32, 0.64, or 0.95 g L-1 of SPL for 24, 72, and 96 h, and genotoxicity was accessed through micronucleus and comet assays...
February 9, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29421602/report-of-two-unrelated-families-with-jalili-syndrome-and-a-novel-nonsense-heterozygous-mutation-in-cnnm4-gene
#15
Célia Márcia Fernandes Maia, Renato Assis Machado, Vera Lúcia Gil-da-Silva-Lopes, Elaine Lustosa-Mendes, Priscila Hae Hyun Rim, Verônica Oliveira Dias, Daniella Reis Barbosa Martelli, Luciano Sólia Nasser, Ricardo D Coletta, Hercílio Martelli-Júnior
Jalili syndrome (JS) is an autosomal recessive disease characterized by a combination of cone-rode retinal dytrophy (CRD) and amelogenesis imperfect (AI). Mutations in cyclin and CBS domain divalent metal cation transport mediator 4 (CNNM4) gene cause JS. Here we described 2 families (3 members) affected by JS. In the first family, JS was caused by the homozygous p.Leu324Pro (c.971T > C) missense mutation and the affected patient developed both CRD and AI. In the second family, a specific combination of a compound heterozygous mutation was found - the p...
February 5, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29405366/correlation-of-right-ventricular-multielectrode-endocardial-unipolar-mapping-and-epicardial-scar
#16
Jonathan Chrispin, Ali Keramati, Fabrizio R Assis, Satish Misra, Tarek Zghaib, Ronald D Berger, Hugh Calkins, Harikrishna Tandri
AIMS: Prior studies identified a relationship between epicardial bipolar and endocardial unipolar voltage. Whether the relationship is valid with smaller multielectrode mapping catheters has not been reported. We explored the association of right ventricular (RV) endocardial unipolar voltage mapping with epicardial bipolar voltage mapping using a multielectrode mapping catheter. METHODS: Electrograms from patients who underwent multielectrode endocardial and epicardial RV electroanatomical mapping during ablation procedures were analyzed...
February 6, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29343741/species-distribution-modelling-contrasting-presence-only-models-with-plot-abundance-data
#17
Vitor H F Gomes, Stéphanie D IJff, Niels Raes, Iêda Leão Amaral, Rafael P Salomão, Luiz de Souza Coelho, Francisca Dionízia de Almeida Matos, Carolina V Castilho, Diogenes de Andrade Lima Filho, Dairon Cárdenas López, Juan Ernesto Guevara, William E Magnusson, Oliver L Phillips, Florian Wittmann, Marcelo de Jesus Veiga Carim, Maria Pires Martins, Mariana Victória Irume, Daniel Sabatier, Jean-François Molino, Olaf S Bánki, José Renan da Silva Guimarães, Nigel C A Pitman, Maria Teresa Fernandez Piedade, Abel Monteagudo Mendoza, Bruno Garcia Luize, Eduardo Martins Venticinque, Evlyn Márcia Moraes de Leão Novo, Percy Núñez Vargas, Thiago Sanna Freire Silva, Angelo Gilberto Manzatto, John Terborgh, Neidiane Farias Costa Reis, Juan Carlos Montero, Katia Regina Casula, Beatriz S Marimon, Ben-Hur Marimon, Euridice N Honorio Coronado, Ted R Feldpausch, Alvaro Duque, Charles Eugene Zartman, Nicolás Castaño Arboleda, Timothy J Killeen, Bonifacio Mostacedo, Rodolfo Vasquez, Jochen Schöngart, Rafael L Assis, Marcelo Brilhante Medeiros, Marcelo Fragomeni Simon, Ana Andrade, William F Laurance, José Luís Camargo, Layon O Demarchi, Susan G W Laurance, Emanuelle de Sousa Farias, Henrique Eduardo Mendonça Nascimento, Juan David Cardenas Revilla, Adriano Quaresma, Flavia R C Costa, Ima Célia Guimarães Vieira, Bruno Barçante Ladvocat Cintra, Hernán Castellanos, Roel Brienen, Pablo R Stevenson, Yuri Feitosa, Joost F Duivenvoorden, Gerardo A Aymard C, Hugo F Mogollón, Natalia Targhetta, James A Comiskey, Alberto Vicentini, Aline Lopes, Gabriel Damasco, Nállarett Dávila, Roosevelt García-Villacorta, Carolina Levis, Juliana Schietti, Priscila Souza, Thaise Emilio, Alfonso Alonso, David Neill, Francisco Dallmeier, Leandro Valle Ferreira, Alejandro Araujo-Murakami, Daniel Praia, Dário Dantas do Amaral, Fernanda Antunes Carvalho, Fernanda Coelho de Souza, Kenneth Feeley, Luzmila Arroyo, Marcelo Petratti Pansonato, Rogerio Gribel, Boris Villa, Juan Carlos Licona, Paul V A Fine, Carlos Cerón, Chris Baraloto, Eliana M Jimenez, Juliana Stropp, Julien Engel, Marcos Silveira, Maria Cristina Peñuela Mora, Pascal Petronelli, Paul Maas, Raquel Thomas-Caesar, Terry W Henkel, Doug Daly, Marcos Ríos Paredes, Tim R Baker, Alfredo Fuentes, Carlos A Peres, Jerome Chave, Jose Luis Marcelo Pena, Kyle G Dexter, Miles R Silman, Peter Møller Jørgensen, Toby Pennington, Anthony Di Fiore, Fernando Cornejo Valverde, Juan Fernando Phillips, Gonzalo Rivas-Torres, Patricio von Hildebrand, Tinde R van Andel, Ademir R Ruschel, Adriana Prieto, Agustín Rudas, Bruce Hoffman, César I A Vela, Edelcilio Marques Barbosa, Egleé L Zent, George Pepe Gallardo Gonzales, Hilda Paulette Dávila Doza, Ires Paula de Andrade Miranda, Jean-Louis Guillaumet, Linder Felipe Mozombite Pinto, Luiz Carlos de Matos Bonates, Natalino Silva, Ricardo Zárate Gómez, Stanford Zent, Therany Gonzales, Vincent A Vos, Yadvinder Malhi, Alexandre A Oliveira, Angela Cano, Bianca Weiss Albuquerque, Corine Vriesendorp, Diego Felipe Correa, Emilio Vilanova Torre, Geertje van der Heijden, Hirma Ramirez-Angulo, José Ferreira Ramos, Kenneth R Young, Maira Rocha, Marcelo Trindade Nascimento, Maria Natalia Umaña Medina, Milton Tirado, Ophelia Wang, Rodrigo Sierra, Armando Torres-Lezama, Casimiro Mendoza, Cid Ferreira, Cláudia Baider, Daniel Villarroel, Henrik Balslev, Italo Mesones, Ligia Estela Urrego Giraldo, Luisa Fernanda Casas, Manuel Augusto Ahuite Reategui, Reynaldo Linares-Palomino, Roderick Zagt, Sasha Cárdenas, William Farfan-Rios, Adeilza Felipe Sampaio, Daniela Pauletto, Elvis H Valderrama Sandoval, Freddy Ramirez Arevalo, Isau Huamantupa-Chuquimaco, Karina Garcia-Cabrera, Lionel Hernandez, Luis Valenzuela Gamarra, Miguel N Alexiades, Susamar Pansini, Walter Palacios Cuenca, William Milliken, Joana Ricardo, Gabriela Lopez-Gonzalez, Edwin Pos, Hans Ter Steege
Species distribution models (SDMs) are widely used in ecology and conservation. Presence-only SDMs such as MaxEnt frequently use natural history collections (NHCs) as occurrence data, given their huge numbers and accessibility. NHCs are often spatially biased which may generate inaccuracies in SDMs. Here, we test how the distribution of NHCs and MaxEnt predictions relates to a spatial abundance model, based on a large plot dataset for Amazonian tree species, using inverse distance weighting (IDW). We also propose a new pipeline to deal with inconsistencies in NHCs and to limit the area of occupancy of the species...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329948/nkp46-receptor-mediated-interferon-%C3%AE-production-by-natural-killer-cells-increases-fibronectin-1-to-alter-tumor-architecture-and-control-metastasis
#18
Ariella Glasner, Assi Levi, Jonatan Enk, Batya Isaacson, Sergey Viukov, Shari Orlanski, Alon Scope, Tzahi Neuman, Claes D Enk, Jacob H Hanna, Veronika Sexl, Stipan Jonjic, Barbara Seliger, Laurence Zitvogel, Ofer Mandelboim
Natural killer (NK) cells are innate lymphoid cells, and their presence within human tumors correlates with better prognosis. However, the mechanisms by which NK cells control tumors in vivo are unclear. Here, we used reflectance confocal microscopy (RCM) imaging in humans and in mice to visualize tumor architecture in vivo. We demonstrated that signaling via the NK cell receptor NKp46 (human) and Ncr1 (mouse) induced interferon-γ (IFN-γ) secretion from intratumoral NK cells. NKp46- and Ncr1-mediated IFN-γ production led to the increased expression of the extracellular matrix protein fibronectin 1 (FN1) in the tumors, which altered primary tumor architecture and resulted in decreased metastases formation...
January 16, 2018: Immunity
https://www.readbyqxmd.com/read/29316786/controlled-growth-and-grafting-of-high-density-au-nanoparticles-on-zinc-oxide-thin-films-by-photo-deposition
#19
Jérémy Cure, Hala Assi, Kévin Cocq, Lorena Marìn, Katia Fajerwerg, Pierre Fau, Eric Bêche, Yves J Chabal, Alain Estève, Carole Rossi
The integration of high-purity nano-objects on substrates remains a great challenge for addressing scaling-up issues in nanotechnology. For instance, grafting gold nanoparticles (NPs) on zinc oxide films, a major step process for catalysis or photovoltaic applications, still remains difficult to master. We report a modified photodeposition (P-D) approach that achieves tight control of the NPs size (7.5 ± 3 nm), shape (spherical), purity, and high areal density (3500 ± 10 NPs/μm2 ) on ZnO films. This deposition method is also compatible with large ZnO surface areas...
February 6, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29245570/-i-desutterella-i-n-gen-a-new-genus-of-luzarinae-orthoptera-grylloidea-phalangopsidae-and-the-first-report-of-the-aracambiae-group-souza-dias-amp-desutter-grandcolas-2014-in-the-amazon
#20
Pedro G B Souza-Dias, Lucas Denadai DE Campos, Francisco DE Assis Ganeo DE Mello
A new genus and two new species of Luzarinae cricket (Grylloidea, Phalangopsidae) are described from the Amazon Rainforest of Brazil and Colombia. Desutterella manauara n. gen. n. sp. and D. colombiana n. gen. n. sp. are described based in characters of external morphology and genitalia. The new genus is characterized by the presence of reduced and pubescent male forewings, with stridulatory vein visible but other areas for sound production and propagation absent, and file teeth very reduced, vestigial. Regarding the male genitalia, Desutterella n...
November 16, 2017: Zootaxa
keyword
keyword
35663
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"