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JOURNAL ARTICLE
Abdulrahman Hm Hassab, David J Hur, Prashanth Vallabhajosyula, George Tellides, Roland Assi
BACKGROUND: Disease of the aorta varies from atherosclerosis to aneurysms with complications including rupture, dissection, and poorly characterized limited tears. We studied limited tears without any mural hematoma, termed intimomedial tears to gain insight into aortic vulnerability to excessive wall stresses. Our premise is that minimal injuries in aortas with sufficient medial resilience to prevent tear progression correspond to initial mechanisms leading to complete structural failure in aortas with significantly compromised medial resilience...
April 9, 2024: JCI Insight
#2
JOURNAL ARTICLE
Andre Lamy, Glenn M Chertow, Michael Jessen, Alonso Collar, Craig D Brown, Charles A Mack, Mohamed Marzouk, Vincent Scavo, T Benton Washburn, David Savage, Julian Smith, Jayme Bennetts, Roland Assi, Christian Shults, Arman Arghami, Javed Butler, P J Devereaux, Richard Zager, Chao Wang, Steve Snapinn, Austin Browne, Jeannette Rodriguez, Stacey Ruiz, Bhupinder Singh
BACKGROUND: RBT-1 is a combination drug of stannic protoporfin (SnPP) and iron sucrose (FeS) that elicits a preconditioning response through activation of antioxidant, anti-inflammatory, and iron-scavenging pathways, as measured by heme oxygenase-1 (HO-1), interleukin-10 (IL-10), and ferritin, respectively. Our primary aim was to determine whether RBT-1 administered before surgery would safely and effectively elicit a preconditioning response in patients undergoing cardiac surgery. METHODS: This phase 2, double-blind, randomised, placebo-controlled, parallel-group, adaptive trial, conducted in 19 centres across the USA, Canada, and Australia, enrolled patients scheduled to undergo non-emergent coronary artery bypass graft (CABG) and/or heart valve surgery with cardiopulmonary bypass...
February 2024: EClinicalMedicine
#3
JOURNAL ARTICLE
Carmelia Oloukoi, Anthony Dohan, Martin Gaillard, Christine Hoeffel, Lionel Groussin-Rouiller, Jérome Bertherat, Anne Jouinot, Guillaume Assié, David Fuks, Mathilde Sibony, Philippe Soyer, Anne-Sophie Jannot, Maxime Barat
PURPOSE: The purpose of this study was to evaluate the capabilities of multiparametric magnetic resonance imaging (MRI) in differentiating between lipid-poor adrenal adenoma (LPAA) and adrenocortical carcinoma (ACC). MATERIALS AND METHODS: Patients of two centers who underwent surgical resection of LPAA or ACC after multiparametric MRI were retrospectively included. A training cohort was used to build a diagnostic algorithm obtained through recursive partitioning based on multiparametric MRI variables, including apparent diffusion coefficient and chemical shift signal ratio (i...
April 3, 2024: Diagnostic and Interventional Imaging
#4
John Ethan Householder, Florian Wittmann, Jochen Schöngart, Maria Teresa Fernandez Piedade, Wolfgang J Junk, Edgardo Manuel Latrubesse, Adriano Costa Quaresma, Layon O Demarchi, Guilherme de S Lobo, Daniel P P de Aguiar, Rafael L Assis, Aline Lopes, Pia Parolin, Iêda Leão do Amaral, Luiz de Souza Coelho, Francisca Dionízia de Almeida Matos, Diógenes de Andrade Lima Filho, Rafael P Salomão, Carolina V Castilho, Juan Ernesto Guevara-Andino, Marcelo de Jesus Veiga Carim, Oliver L Phillips, Dairon Cárdenas López, William E Magnusson, Daniel Sabatier, Juan David Cardenas Revilla, Jean-François Molino, Mariana Victória Irume, Maria Pires Martins, José Renan da Silva Guimarães, José Ferreira Ramos, Domingos de Jesus Rodrigues, Olaf S Bánki, Carlos A Peres, Nigel C A Pitman, Joseph E Hawes, Everton José Almeida, Luciane Ferreira Barbosa, Larissa Cavalheiro, Márcia Cléia Vilela Dos Santos, Bruno Garcia Luize, Evlyn Márcia Moraes de Leão Novo, Percy Núñez Vargas, Thiago Sanna Freire Silva, Eduardo Martins Venticinque, Angelo Gilberto Manzatto, Neidiane Farias Costa Reis, John Terborgh, Katia Regina Casula, Flávia R C Costa, Euridice N Honorio Coronado, Abel Monteagudo Mendoza, Juan Carlos Montero, Ted R Feldpausch, Gerardo A Aymard C, Chris Baraloto, Nicolás Castaño Arboleda, Julien Engel, Pascal Petronelli, Charles Eugene Zartman, Timothy J Killeen, Lorena Maniguaje Rincón, Beatriz S Marimon, Ben Hur Marimon-Junior, Juliana Schietti, Thaiane R Sousa, Rodolfo Vasquez, Bonifacio Mostacedo, Dário Dantas do Amaral, Hernán Castellanos, Marcelo Brilhante de Medeiros, Marcelo Fragomeni Simon, Ana Andrade, José Luís Camargo, William F Laurance, Susan G W Laurance, Emanuelle de Sousa Farias, Maria Aparecida Lopes, José Leonardo Lima Magalhães, Henrique Eduardo Mendonça Nascimento, Helder Lima de Queiroz, Roel Brienen, Pablo R Stevenson, Alejandro Araujo-Murakami, Tim R Baker, Bruno Barçante Ladvocat Cintra, Yuri Oliveira Feitosa, Hugo F Mogollón, Janaína Costa Noronha, Flávia Rodrigues Barbosa, Rainiellen de Sá Carpanedo, Joost F Duivenvoorden, Miles R Silman, Leandro Valle Ferreira, Carolina Levis, José Rafael Lozada, James A Comiskey, Freddie C Draper, José Julio de Toledo, Gabriel Damasco, Nállarett Dávila, Roosevelt García-Villacorta, Alberto Vicentini, Fernando Cornejo Valverde, Alfonso Alonso, Luzmila Arroyo, Francisco Dallmeier, Vitor H F Gomes, Eliana M Jimenez, David Neill, Maria Cristina Peñuela Mora, Fernanda Antunes Carvalho, Fernanda Coelho de Souza, Kenneth J Feeley, Rogerio Gribel, Marcelo Petratti Pansonato, Marcos Ríos Paredes, Jos Barlow, Erika Berenguer, Kyle G Dexter, Joice Ferreira, Paul V A Fine, Marcelino Carneiro Guedes, Isau Huamantupa-Chuquimaco, Juan Carlos Licona, Toby Pennington, Boris Eduardo Villa Zegarra, Vincent Antoine Vos, Carlos Cerón, Émile Fonty, Terry W Henkel, Paul Maas, Edwin Pos, Marcos Silveira, Juliana Stropp, Raquel Thomas, Doug Daly, William Milliken, Guido Pardo Molina, Ima Célia Guimarães Vieira, Bianca Weiss Albuquerque, Wegliane Campelo, Thaise Emilio, Alfredo Fuentes, Bente Klitgaard, José Luis Marcelo Pena, Priscila F Souza, J Sebastián Tello, Corine Vriesendorp, Jerome Chave, Anthony Di Fiore, Renato Richard Hilário, Luciana de Oliveira Pereira, Juan Fernando Phillips, Gonzalo Rivas-Torres, Tinde R van Andel, Patricio von Hildebrand, William Balee, Edelcilio Marques Barbosa, Luiz Carlos de Matos Bonates, Hilda Paulette Dávila Doza, Ricardo Zárate Gómez, Therany Gonzales, George Pepe Gallardo Gonzales, Bruce Hoffman, André Braga Junqueira, Yadvinder Malhi, Ires Paula de Andrade Miranda, Linder Felipe Mozombite-Pinto, Adriana Prieto, Agustín Rudas, Ademir R Ruschel, Natalino Silva, César I A Vela, Stanford Zent, Egleé L Zent, Angela Cano, Yrma Andreina Carrero Márquez, Diego F Correa, Janaina Barbosa Pedrosa Costa, Bernardo Monteiro Flores, David Galbraith, Milena Holmgren, Michelle Kalamandeen, Marcelo Trindade Nascimento, Alexandre A Oliveira, Hirma Ramirez-Angulo, Maira Rocha, Veridiana Vizoni Scudeller, Rodrigo Sierra, Milton Tirado, Maria Natalia Umaña, Geertje van der Heijden, Emilio Vilanova Torre, Manuel Augusto Ahuite Reategui, Cláudia Baider, Henrik Balslev, Sasha Cárdenas, Luisa Fernanda Casas, William Farfan-Rios, Cid Ferreira, Reynaldo Linares-Palomino, Casimiro Mendoza, Italo Mesones, Germaine Alexander Parada, Armando Torres-Lezama, Ligia Estela Urrego Giraldo, Daniel Villarroel, Roderick Zagt, Miguel N Alexiades, Edmar Almeida de Oliveira, Karina Garcia-Cabrera, Lionel Hernandez, Walter Palacios Cuenca, Susamar Pansini, Daniela Pauletto, Freddy Ramirez Arevalo, Adeilza Felipe Sampaio, Elvis H Valderrama Sandoval, Luis Valenzuela Gamarra, Hans Ter Steege
No abstract text is available yet for this article.
April 2, 2024: Nature Ecology & Evolution
#5
JOURNAL ARTICLE
John Ethan Householder, Florian Wittmann, Jochen Schöngart, Maria Teresa Fernandez Piedade, Wolfgang J Junk, Edgardo Manuel Latrubesse, Adriano Costa Quaresma, Layon O Demarchi, Guilherme de S Lobo, Daniel P P de Aguiar, Rafael L Assis, Aline Lopes, Pia Parolin, Iêda Leão do Amaral, Luiz de Souza Coelho, Francisca Dionízia de Almeida Matos, Diógenes de Andrade Lima Filho, Rafael P Salomão, Carolina V Castilho, Juan Ernesto Guevara-Andino, Marcelo de Jesus Veiga Carim, Oliver L Phillips, Dairon Cárdenas López, William E Magnusson, Daniel Sabatier, Juan David Cardenas Revilla, Jean-François Molino, Mariana Victória Irume, Maria Pires Martins, José Renan da Silva Guimarães, José Ferreira Ramos, Domingos de Jesus Rodrigues, Olaf S Bánki, Carlos A Peres, Nigel C A Pitman, Joseph E Hawes, Everton José Almeida, Luciane Ferreira Barbosa, Larissa Cavalheiro, Márcia Cléia Vilela Dos Santos, Bruno Garcia Luize, Evlyn Márcia Moraes de Leão Novo, Percy Núñez Vargas, Thiago Sanna Freire Silva, Eduardo Martins Venticinque, Angelo Gilberto Manzatto, Neidiane Farias Costa Reis, John Terborgh, Katia Regina Casula, Flávia R C Costa, Euridice N Honorio Coronado, Abel Monteagudo Mendoza, Juan Carlos Montero, Ted R Feldpausch, Gerardo A Aymard C, Chris Baraloto, Nicolás Castaño Arboleda, Julien Engel, Pascal Petronelli, Charles Eugene Zartman, Timothy J Killeen, Lorena Maniguaje Rincón, Beatriz S Marimon, Ben Hur Marimon-Junior, Juliana Schietti, Thaiane R Sousa, Rodolfo Vasquez, Bonifacio Mostacedo, Dário Dantas do Amaral, Hernán Castellanos, Marcelo Brilhante de Medeiros, Marcelo Fragomeni Simon, Ana Andrade, José Luís Camargo, William F Laurance, Susan G W Laurance, Emanuelle de Sousa Farias, Maria Aparecida Lopes, José Leonardo Lima Magalhães, Henrique Eduardo Mendonça Nascimento, Helder Lima de Queiroz, Roel Brienen, Pablo R Stevenson, Alejandro Araujo-Murakami, Tim R Baker, Bruno Barçante Ladvocat Cintra, Yuri Oliveira Feitosa, Hugo F Mogollón, Janaína Costa Noronha, Flávia Rodrigues Barbosa, Rainiellen de Sá Carpanedo, Joost F Duivenvoorden, Miles R Silman, Leandro Valle Ferreira, Carolina Levis, José Rafael Lozada, James A Comiskey, Freddie C Draper, José Julio de Toledo, Gabriel Damasco, Nállarett Dávila, Roosevelt García-Villacorta, Alberto Vicentini, Fernando Cornejo Valverde, Alfonso Alonso, Luzmila Arroyo, Francisco Dallmeier, Vitor H F Gomes, Eliana M Jimenez, David Neill, Maria Cristina Peñuela Mora, Fernanda Antunes Carvalho, Fernanda Coelho de Souza, Kenneth J Feeley, Rogerio Gribel, Marcelo Petratti Pansonato, Marcos Ríos Paredes, Jos Barlow, Erika Berenguer, Kyle G Dexter, Joice Ferreira, Paul V A Fine, Marcelino Carneiro Guedes, Isau Huamantupa-Chuquimaco, Juan Carlos Licona, Toby Pennington, Boris Eduardo Villa Zegarra, Vincent Antoine Vos, Carlos Cerón, Émile Fonty, Terry W Henkel, Paul Maas, Edwin Pos, Marcos Silveira, Juliana Stropp, Raquel Thomas, Doug Daly, William Milliken, Guido Pardo Molina, Ima Célia Guimarães Vieira, Bianca Weiss Albuquerque, Wegliane Campelo, Thaise Emilio, Alfredo Fuentes, Bente Klitgaard, José Luis Marcelo Pena, Priscila F Souza, J Sebastián Tello, Corine Vriesendorp, Jerome Chave, Anthony Di Fiore, Renato Richard Hilário, Luciana de Oliveira Pereira, Juan Fernando Phillips, Gonzalo Rivas-Torres, Tinde R van Andel, Patricio von Hildebrand, William Balee, Edelcilio Marques Barbosa, Luiz Carlos de Matos Bonates, Hilda Paulette Dávila Doza, Ricardo Zárate Gómez, Therany Gonzales, George Pepe Gallardo Gonzales, Bruce Hoffman, André Braga Junqueira, Yadvinder Malhi, Ires Paula de Andrade Miranda, Linder Felipe Mozombite-Pinto, Adriana Prieto, Agustín Rudas, Ademir R Ruschel, Natalino Silva, César I A Vela, Stanford Zent, Egleé L Zent, Angela Cano, Yrma Andreina Carrero Márquez, Diego F Correa, Janaina Barbosa Pedrosa Costa, Bernardo Monteiro Flores, David Galbraith, Milena Holmgren, Michelle Kalamandeen, Marcelo Trindade Nascimento, Alexandre A Oliveira, Hirma Ramirez-Angulo, Maira Rocha, Veridiana Vizoni Scudeller, Rodrigo Sierra, Milton Tirado, Maria Natalia Umaña, Geertje van der Heijden, Emilio Vilanova Torre, Manuel Augusto Ahuite Reategui, Cláudia Baider, Henrik Balslev, Sasha Cárdenas, Luisa Fernanda Casas, William Farfan-Rios, Cid Ferreira, Reynaldo Linares-Palomino, Casimiro Mendoza, Italo Mesones, Germaine Alexander Parada, Armando Torres-Lezama, Ligia Estela Urrego Giraldo, Daniel Villarroel, Roderick Zagt, Miguel N Alexiades, Edmar Almeida de Oliveira, Karina Garcia-Cabrera, Lionel Hernandez, Walter Palacios Cuenca, Susamar Pansini, Daniela Pauletto, Freddy Ramirez Arevalo, Adeilza Felipe Sampaio, Elvis H Valderrama Sandoval, Luis Valenzuela Gamarra, Hans Ter Steege
Amazonia's floodplain system is the largest and most biodiverse on Earth. Although forests are crucial to the ecological integrity of floodplains, our understanding of their species composition and how this may differ from surrounding forest types is still far too limited, particularly as changing inundation regimes begin to reshape floodplain tree communities and the critical ecosystem functions they underpin. Here we address this gap by taking a spatially explicit look at Amazonia-wide patterns of tree-species turnover and ecological specialization of the region's floodplain forests...
March 11, 2024: Nature Ecology & Evolution
#6
EDITORIAL
David N Assis
New England Journal of Medicine, Volume 390, Issue 9, Page 853-854, February 2024.
February 21, 2024: New England Journal of Medicine
#7
JOURNAL ARTICLE
Sonali Kochhar, David N Assis, Cara Mack, Hector S Izurieta, Luigi Muratori, Alma Munoz, Dale Nordenberg, Jane F Gidudu, Erin F Blau, John M Vierling
This report introduces a Brighton Collaboration (BC) case definition for autoimmune hepatitis (AIH), which has been classified as a priority adverse event of special interest (AESI), as there were possible cases seen following COVID-19 vaccination. The case definition was developed by a group of subject matter and BC process experts to facilitate safety data comparability across pre- and post-licensure clinical trials, as well as pharmacovigilance activities in multiple settings with diverse resources and healthcare access...
February 16, 2024: Vaccine
#8
REVIEW
Michael Verret, Nhat H Lam, Manoj Lalu, Stuart G Nicholls, Alexis F Turgeon, Daniel I McIsaac, Myriam Hamtiaux, John Bao Phuc Le, Ian Gilron, Lucy Yang, Mahrukh Kaimkhani, Alexandre Assi, David El-Adem, Makenna Timm, Peter Tai, Joelle Amir, Sriyathavan Srichandramohan, Abdulaziz Al-Mazidi, Nicholas A Fergusson, Brian Hutton, Fiona Zivkovic, Megan Graham, Maxime Lê, Allison Geist, Mélanie Bérubé, Patricia Poulin, Risa Shorr, Helena Daudt, Guillaume Martel, Jason McVicar, Husein Moloo, Dean A Fergusson
BACKGROUND: Postoperative patient-centred outcome measures are essential to capture the patient's experience after surgery. Although a large number of pharmacologic opioid minimisation strategies (i.e. opioid alternatives) are used for patients undergoing surgery, it remains unclear which strategies are most promising in terms of patient-centred outcome improvements. This scoping review had two main objectives: (1) to map and describe evidence from clinical trials assessing the patient-centred effectiveness of pharmacologic intraoperative opioid minimisation strategies in adult surgical patients, and (2) to identify promising pharmacologic opioid minimisation strategies...
February 7, 2024: British Journal of Anaesthesia
#9
JOURNAL ARTICLE
Ismael Z Assi, Sabrina R Lynch, Brian D Ricker, Siddhant V Ranjane, David M Williams, Thomas W Wakefield, Andrea T Obi, C Alberto Figueroa
Introduction: Iliac vein compression syndrome (IVCS) is present in over 20% of the population and is associated with left leg pain, swelling, and thrombosis. IVCS symptoms are thought to be induced by altered pelvic hemodynamics, however, there currently exists a knowledge gap on the hemodynamic differences between IVCS and healthy patients. To elucidate those differences, we carried out a patient-specific, computational modeling comparative study. Methods: Computed tomography and ultrasound velocity and area data were used to build and validate computational models for a cohort of IVCS (N = 4, Subject group) and control (N = 4, Control group) patients...
2024: Frontiers in Bioengineering and Biotechnology
#10
JOURNAL ARTICLE
Maryam Yazdanfar, Joseph Zepeda, Richard Dean, Jialin Wu, Cynthia Levy, David Goldberg, Craig Lammert, Stacey Prenner, K Rajender Reddy, Daniel Pratt, Lisa Forman, David N Assis, Ellina Lytvyak, Aldo J Montano-Loza, Stuart C Gordon, Elizabeth J Carey, Joseph Ahn, Barry Schlansky, Joshua Korzenik, Raffi Karagozian, Bilal Hameed, Shaun Chandna, Lei Yu, Christopher L Bowlus
BACKGROUND: The natural history of primary sclerosing cholangitis (PSC) among African Americans (AA) is not well understood. METHODS: Transplant-free survival and hepatic decompensation-free survival were assessed using a retrospective research registry from 16 centers throughout North America. Patients with PSC alive without liver transplantation after 2008 were included. Diagnostic delay was defined from the first abnormal liver test to the first abnormal cholangiogram/liver biopsy...
February 1, 2024: Hepatology Communications
#11
REVIEW
Antoine Bejjani, Candrika D Khairani, Ali Assi, Gregory Piazza, Parham Sadeghipour, Azita H Talasaz, John Fanikos, Jean M Connors, Deborah M Siegal, Geoffrey D Barnes, Karlyn A Martin, Dominick J Angiolillo, Dawn Kleindorfer, Manuel Monreal, David Jimenez, Saskia Middeldorp, Mitchell S V Elkind, Christian T Ruff, Samuel Z Goldhaber, Harlan M Krumholz, Roxana Mehran, Mary Cushman, John W Eikelboom, Gregory Y H Lip, Jeffrey I Weitz, Renato D Lopes, Behnood Bikdeli
For most patients, direct oral anticoagulants (DOACs) are preferred over vitamin K antagonists for stroke prevention in atrial fibrillation and for venous thromboembolism treatment. However, randomized controlled trials suggest that DOACs may not be as efficacious or as safe as the current standard of care in conditions such as mechanical heart valves, thrombotic antiphospholipid syndrome, and atrial fibrillation associated with rheumatic heart disease. DOACs do not provide a net benefit in conditions such as embolic stroke of undetermined source...
January 23, 2024: Journal of the American College of Cardiology
#12
JOURNAL ARTICLE
Oscar Caetano Silva-Neto, Caio Silva Assis Felix, Leonardo de Oliveira Aguiar, Mauricio Brandão Dos Santos, Silvio Cunha, Jorge Mauricio David
This study describes methodologies for extracting and isolating bergenin, a C-glucoside of 4-O-methylgallic acid found in some plants and it presents various in vitro and in vivo biological activities. Bergenin was previously obtained from the Pelthophorum dubim (Fabaceae) roots with a good yield. Conventional chromatographic procedures of the CHCl3 soluble fraction of the MeOH extract gave 3.62% of this glucoside. An HPLC/DAD method was also developed and validated for bergenin and its precursor, gallic acid quantifications...
January 13, 2024: BMC chemistry
#13
JOURNAL ARTICLE
Declan L M Cooper, Simon L Lewis, Martin J P Sullivan, Paulo I Prado, Hans Ter Steege, Nicolas Barbier, Ferry Slik, Bonaventure Sonké, Corneille E N Ewango, Stephen Adu-Bredu, Kofi Affum-Baffoe, Daniel P P de Aguiar, Manuel Augusto Ahuite Reategui, Shin-Ichiro Aiba, Bianca Weiss Albuquerque, Francisca Dionízia de Almeida Matos, Alfonso Alonso, Christian A Amani, Dário Dantas do Amaral, Iêda Leão do Amaral, Ana Andrade, Ires Paula de Andrade Miranda, Ilondea B Angoboy, Alejandro Araujo-Murakami, Nicolás Castaño Arboleda, Luzmila Arroyo, Peter Ashton, Gerardo A Aymard C, Cláudia Baider, Timothy R Baker, Michael Philippe Bessike Balinga, Henrik Balslev, Lindsay F Banin, Olaf S Bánki, Chris Baraloto, Edelcilio Marques Barbosa, Flávia Rodrigues Barbosa, Jos Barlow, Jean-Francois Bastin, Hans Beeckman, Serge Begne, Natacha Nssi Bengone, Erika Berenguer, Nicholas Berry, Robert Bitariho, Pascal Boeckx, Jan Bogaert, Bernard Bonyoma, Patrick Boundja, Nils Bourland, Faustin Boyemba Bosela, Fabian Brambach, Roel Brienen, David F R P Burslem, José Luís Camargo, Wegliane Campelo, Angela Cano, Sasha Cárdenas, Dairon Cárdenas López, Rainiellen de Sá Carpanedo, Yrma Andreina Carrero Márquez, Fernanda Antunes Carvalho, Luisa Fernanda Casas, Hernán Castellanos, Carolina V Castilho, Carlos Cerón, Colin A Chapman, Jerome Chave, Phourin Chhang, Wanlop Chutipong, George B Chuyong, Bruno Barçante Ladvocat Cintra, Connie J Clark, Fernanda Coelho de Souza, James A Comiskey, David A Coomes, Fernando Cornejo Valverde, Diego F Correa, Flávia R C Costa, Janaina Barbosa Pedrosa Costa, Pierre Couteron, Heike Culmsee, Aida Cuni-Sanchez, Francisco Dallmeier, Gabriel Damasco, Gilles Dauby, Nállarett Dávila, Hilda Paulette Dávila Doza, Jose Don T De Alban, Rafael L de Assis, Charles De Canniere, Thales De Haulleville, Marcelo de Jesus Veiga Carim, Layon O Demarchi, Kyle G Dexter, Anthony Di Fiore, Hazimah Haji Mohammad Din, Mathias I Disney, Brice Yannick Djiofack, Marie-Noël K Djuikouo, Tran Van Do, Jean-Louis Doucet, Freddie C Draper, Vincent Droissart, Joost F Duivenvoorden, Julien Engel, Vittoria Estienne, William Farfan-Rios, Sophie Fauset, Kenneth J Feeley, Yuri Oliveira Feitosa, Ted R Feldpausch, Cid Ferreira, Joice Ferreira, Leandro Valle Ferreira, Christine D Fletcher, Bernardo Monteiro Flores, Alusine Fofanah, Ernest G Foli, Émile Fonty, Gabriella M Fredriksson, Alfredo Fuentes, David Galbraith, George Pepe Gallardo Gonzales, Karina Garcia-Cabrera, Roosevelt García-Villacorta, Vitor H F Gomes, Ricardo Zárate Gómez, Therany Gonzales, Rogerio Gribel, Marcelino Carneiro Guedes, Juan Ernesto Guevara, Khalid Rehman Hakeem, Jefferson S Hall, Keith C Hamer, Alan C Hamilton, David J Harris, Rhett D Harrison, Terese B Hart, Andy Hector, Terry W Henkel, John Herbohn, Mireille B N Hockemba, Bruce Hoffman, Milena Holmgren, Euridice N Honorio Coronado, Isau Huamantupa-Chuquimaco, Wannes Hubau, Nobuo Imai, Mariana Victória Irume, Patrick A Jansen, Kathryn J Jeffery, Eliana M Jimenez, Tommaso Jucker, André Braga Junqueira, Michelle Kalamandeen, Narcisse G Kamdem, Kuswata Kartawinata, Emmanuel Kasongo Yakusu, John M Katembo, Elizabeth Kearsley, David Kenfack, Michael Kessler, Thiri Toe Khaing, Timothy J Killeen, Kanehiro Kitayama, Bente Klitgaard, Nicolas Labrière, Yves Laumonier, Susan G W Laurance, William F Laurance, Félix Laurent, Tinh Cong Le, Trai Trong Le, Miguel E Leal, Evlyn Márcia Leão de Moraes Novo, Aurora Levesley, Moses B Libalah, Juan Carlos Licona, Diógenes de Andrade Lima Filho, Jeremy A Lindsell, Aline Lopes, Maria Aparecida Lopes, Jon C Lovett, Richard Lowe, José Rafael Lozada, Xinghui Lu, Nestor K Luambua, Bruno Garcia Luize, Paul Maas, José Leonardo Lima Magalhães, William E Magnusson, Ni Putu Diana Mahayani, Jean-Remy Makana, Yadvinder Malhi, Lorena Maniguaje Rincón, Asyraf Mansor, Angelo Gilberto Manzatto, Beatriz S Marimon, Ben Hur Marimon-Junior, Andrew R Marshall, Maria Pires Martins, Faustin M Mbayu, Marcelo Brilhante de Medeiros, Italo Mesones, Faizah Metali, Vianet Mihindou, Jerome Millet, William Milliken, Hugo F Mogollón, Jean-François Molino, Mohd Nizam Mohd Said, Abel Monteagudo Mendoza, Juan Carlos Montero, Sam Moore, Bonifacio Mostacedo, Linder Felipe Mozombite Pinto, Sharif Ahmed Mukul, Pantaleo K T Munishi, Hidetoshi Nagamasu, Henrique Eduardo Mendonça Nascimento, Marcelo Trindade Nascimento, David Neill, Reuben Nilus, Janaína Costa Noronha, Laurent Nsenga, Percy Núñez Vargas, Lucas Ojo, Alexandre A Oliveira, Edmar Almeida de Oliveira, Fidèle Evouna Ondo, Walter Palacios Cuenca, Susamar Pansini, Marcelo Petratti Pansonato, Marcos Ríos Paredes, Ekananda Paudel, Daniela Pauletto, Richard G Pearson, José Luis Marcelo Pena, R Toby Pennington, Carlos A Peres, Andrea Permana, Pascal Petronelli, Maria Cristina Peñuela Mora, Juan Fernando Phillips, Oliver L Phillips, Georgia Pickavance, Maria Teresa Fernandez Piedade, Nigel C A Pitman, Pierre Ploton, Andreas Popelier, John R Poulsen, Adriana Prieto, Richard B Primack, Hari Priyadi, Lan Qie, Adriano Costa Quaresma, Helder Lima de Queiroz, Hirma Ramirez-Angulo, José Ferreira Ramos, Neidiane Farias Costa Reis, Jan Reitsma, Juan David Cardenas Revilla, Terhi Riutta, Gonzalo Rivas-Torres, Iyan Robiansyah, Maira Rocha, Domingos de Jesus Rodrigues, M Elizabeth Rodriguez-Ronderos, Francesco Rovero, Andes H Rozak, Agustín Rudas, Ervan Rutishauser, Daniel Sabatier, Le Bienfaiteur Sagang, Adeilza Felipe Sampaio, Ismayadi Samsoedin, Manichanh Satdichanh, Juliana Schietti, Jochen Schöngart, Veridiana Vizoni Scudeller, Naret Seuaturien, Douglas Sheil, Rodrigo Sierra, Miles R Silman, Thiago Sanna Freire Silva, José Renan da Silva Guimarães, Murielle Simo-Droissart, Marcelo Fragomeni Simon, Plinio Sist, Thaiane R Sousa, Emanuelle de Sousa Farias, Luiz de Souza Coelho, Dominick V Spracklen, Suzanne M Stas, Robert Steinmetz, Pablo R Stevenson, Juliana Stropp, Rahayu S Sukri, Terry C H Sunderland, Eizi Suzuki, Michael D Swaine, Jianwei Tang, James Taplin, David M Taylor, J Sebastián Tello, John Terborgh, Nicolas Texier, Ida Theilade, Duncan W Thomas, Raquel Thomas, Sean C Thomas, Milton Tirado, Benjamin Toirambe, José Julio de Toledo, Kyle W Tomlinson, Armando Torres-Lezama, Hieu Dang Tran, John Tshibamba Mukendi, Roven D Tumaneng, Maria Natalia Umaña, Peter M Umunay, Ligia Estela Urrego Giraldo, Elvis H Valderrama Sandoval, Luis Valenzuela Gamarra, Tinde R Van Andel, Martin van de Bult, Jaqueline van de Pol, Geertje van der Heijden, Rodolfo Vasquez, César I A Vela, Eduardo Martins Venticinque, Hans Verbeeck, Rizza Karen A Veridiano, Alberto Vicentini, Ima Célia Guimarães Vieira, Emilio Vilanova Torre, Daniel Villarroel, Boris Eduardo Villa Zegarra, Jason Vleminckx, Patricio von Hildebrand, Vincent Antoine Vos, Corine Vriesendorp, Edward L Webb, Lee J T White, Serge Wich, Florian Wittmann, Roderick Zagt, Runguo Zang, Charles Eugene Zartman, Lise Zemagho, Egleé L Zent, Stanford Zent
Trees structure the Earth's most biodiverse ecosystem, tropical forests. The vast number of tree species presents a formidable challenge to understanding these forests, including their response to environmental change, as very little is known about most tropical tree species. A focus on the common species may circumvent this challenge. Here we investigate abundance patterns of common tree species using inventory data on 1,003,805 trees with trunk diameters of at least 10 cm across 1,568 locations1-6 in closed-canopy, structurally intact old-growth tropical forests in Africa, Amazonia and Southeast Asia...
January 10, 2024: Nature
#14
JOURNAL ARTICLE
Caio de Assis Moura Tavares, Luciano César Pontes de Azevedo, Álvaro Rea-Neto, Niklas Söderberg Campos, Cristina Prata Amendola, Ricardo Reinaldo Bergo, Amanda Christina Kozesinski-Nakatani, Paula Geraldes David-João, Glauco Adrieno Westphal, Mário Roberto Rezende Guimarães Júnior, Suzana Margareth Ajeje Lobo, Marcos Soares Tavares, Marianna Deway Andrade Dracoulakis, Guilherme Martins de Souza, Guacyra Margarita Batista de Almeida, Otavio Celso Eluf Gebara, Pablo Oscar Tomba, Camila Santos N Albuquerque, Mariana Castaldi Ramalho Silva, Adriano José Pereira, Lucas Petri Damiani, Thiago Domingos Corrêa, Ary Serpa-Neto, Otavio Berwanger, Fernando Godinho Zampieri
BACKGROUND: Critical illness is a major ongoing health care burden worldwide and is associated with high mortality rates. Sodium-glucose cotransporter-2 inhibitors have consistently shown benefits in cardiovascular and renal outcomes. The effects of sodium-glucose cotransporter-2 inhibitors in acute illness have not been properly investigated. METHODS: DEFENDER is an investigator-initiated, multicenter, randomized, open-label trial designed to evaluate the efficacy and safety of dapagliflozin in 500 adult participants with acute organ dysfunction who are hospitalized in the intensive care unit...
2023: Crit Care Sci
#15
David González-Fernández, Sergio Raposeiras-Roubín, André González-García, Carla Iglesias-Otero, Andrés Íñiguez-Romo, Emad Abu-Assi
No abstract text is available yet for this article.
December 15, 2023: Revista Española de Cardiología
#16
JOURNAL ARTICLE
Mohammed Ibrahim Mohialdeen Gubari, Falah Wadi, Khalid Anwar Hama-Ghareeb, Fatah H Fatah, Mostafa Hosseini, Karzan Rafiq Wale, David Hipgrave, Sazan Raouf Ali, Shaho Osman Mahmood, Waleed Ezzat Khadium, Hayman Hasan Mohammed, Sara Feal Jaafer, Najeeb Mohammed Al Saadi, Kardar Anwar Mohammed, Shireen Salih Saeed, Mohammad Yousif Mohammad, Waleed Hamid Khudhur, Mohammed Wael Saleh, Yousra Saadi Sheat, Khaldoon Khaleel Ibrahim, Marwa Nabeil Salah, Abdulmonem Hazim Abdullah, Dashne Shamall Omer, Rafeeq Naseraldeen Ghafur, Kashma Ali Mustafa, Aryan Othman Faraj, Trifa Bhjat Ali, Kamal Aziz Enayat, Ronak Assi Wahab, Ibrahim Ahmed Ali Al-Jaf, Nazanin Hama Hama Amin, Dina Dlshad Jaff, Aram Mohammed Bra, Shwan Kanabi Ahmed, Banaz Nabi Rasool, Fatimah Khalis Jamal, Tango Dhahir Mohammed, Maryam Arab Azeez
Objectives: The present study was carried out to investigate COVID-19 vaccination coverage among populations of internally displaced persons (IDPs), refugees, and host communities in northern Iraq and the related underlying factors. Methods: Through a cross-sectional study conducted in five governorates in April-May 2022, 4,564 individuals were surveyed. Data were collected through an adapted questionnaire designed to gather data on participants. Results: 4,564 subjects were included (59.55% were 19-45 years old; 54...
2023: International Journal of Public Health
#17
JOURNAL ARTICLE
José Lopes Tabatinga Neto, Gabriela Ejima Mie Basso, David Nunes de Lima, Eduardo Soares Ferreira, Denisse Sales Paula, Antônio Miguel Furtado Leitão, Antonio Brazil Viana, Florian Patrick Thomas, Francisco de Assis Aquino Gondim
BACKGROUND: Detailed information about the electromyography practice in Brazil is largely unavailable. OBJECTIVE: To evaluate where and how electromyography is performed in Brazil, as well as regional disparities and the professional and academic credentials of electromyographers. METHODS: We conducted an internet-based survey of active Brazilian electromyographers. The websites of health insurance companies, professional academies, medical cooperatives, online search engines, and social networks in each Brazilian state were screened and we evaluated the credentials of each electromyographer listed in the Brazilian Federal Medical Board (BFMB) registration website and their online curricula vitae in the Brazilian National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq, in Portuguese)...
November 2023: Arquivos de Neuro-psiquiatria
#18
REVIEW
Thaís Barreto Santos, Leonardo Gomes Cavalieri de Moraes, Paulo Anastácio Furtado Pacheco, Douglas Galdino Dos Santos, Rafaella Machado de Assis Cabral Ribeiro, Caroline Dos Santos Moreira, David Rodrigues da Rocha
Parkinson's disease (PD) is a degenerative disease that affects approximately 6.1 million people and is primarily caused by the loss of dopaminergic neurons. Naphthoquinones have several biological activities explored in the literature, including neuroprotective effects. Therefore, this review shows an overview of naphthoquinones with neuroprotective effects, such as shikonin, plumbagin and vitamin K, that prevented oxidative stress, in addition to multiple mechanisms. Synthetic naphthoquinones with inhibitory activity on the P2X7 receptor were also found, leading to a neuroprotective effect on Neuro-2a cells...
November 8, 2023: Pharmaceuticals
#19
JOURNAL ARTICLE
José Araújo Souto-Neto, Daniela Dantas David, Giovanna Zanetti, Cristhian Sua-Cespedes, Natalie Villar Freret-Meurer, Maria Nathália Moraes, Leonardo Vinicius Monteiro de Assis, Ana Maria de Lauro Castrucci
Light is a strong stimulus for the sensory and endocrine systems. The opsins constitute a large family of proteins that can respond to specific light wavelengths. Hippocampus reidi is a near-threatened seahorse that has a diverse color pattern and sexual dimorphism. Over the years, H. reidi's unique characteristics, coupled with its high demand and over-exploitation for the aquarium trade, have raised concerns about its conservation, primarily due to their significant impact on wild populations. Here, we characterized chromatophore types in juvenile and adult H...
November 14, 2023: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
#20
JOURNAL ARTICLE
Renata Freitas de A T Calumby, Flávia Oliveira de Lima, Gildomar Lima Valasques Junior, Jener David Gonçalves Santos, Pedro Felipe Pereira Chaves, Lucimara Mach Côrtes Cordeiro, Cristiane Flora Villarreal, Milena Botelho Pereira Soares, Elisangela Fabiana Boffo, Sandra Aparecida de Assis
The management of inflammatory states typically involves non-steroidal anti-inflammatory drugs (NSAIDs) and opiates. Understanding the mechanisms underlying the processing of nociceptive information from potential alternatives such as some polysaccharides may enable new and meaningful therapeutic approaches. In this study, α-D-mannan isolated from the Kluyveromyces marxianus cell wall produced antinociceptive effects in models of inflammatory pain (formalin and complete Freund's adjuvant tests). Furthermore, α-D-mannan reduced paw edema and interleukin-6 (IL-6) production after carrageenan-induced inflammation...
November 11, 2023: Archives of Microbiology
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