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Henry L Elliott, Peter A Meredith
AIM: To undertake a review of the evidence that nifedipine GITS and lercanidipine are therapeutically equivalent in the management of essential hypertension. METHODS: A systematic review of the published literature was prompted by the findings of two meta-analyses which indicated that there was a lower incidence of peripheral (ankle) oedema with lercanidipine. However, neither meta-analysis gave detailed attention to comparative antihypertensive efficacy or cardiovascular protection...
June 26, 2014: World Journal of Cardiology
M Zenz, M Strumpf, A Willweber-Strumpf
Opioids are given for acute intra- and postope-rative pain relief or for chronic cancer pain. In the literature there are only rare and contradictory reports on the oral administration of opioids for chronic non-malignant pain. However, there is no reason to withhold strong analgesics for patients with severe pain. When all other thrapeutic measures fail to control pain, patients with non-malignant pain can also be treated by opioids. We report 70 patients with severe pain who were given opioids as the ultima ratio in pain therapy: 50 received buprenorphine sublingual tablets, 13 received morphine sustained release tablets and the remaining 7 were treated with other opioids...
March 1990: Der Schmerz
M C Nahata, D A Powell
Bioavailability of chloramphenicol and kinetics of chloramphenicol succinate and chloramphenicol were studied in 12 patients. Chloramphenicol succinate, 25 mg/kg, was injected intravenously every 6 hr over 0.5 to 1 hr. Both the drug and the prodrug were analyzed by high-pressure liquid chromatography. Bioabailability of chlorampenicol ranged from 0.55 to 0.92 and total, renal, and nonrenal clearance from 6.81 to 98.22, 2.54 to 26.90, and 3.73 to 87.38 ml/m2/min, while clearances of chloramphenicol succinate ranged from 84...
September 1981: Clinical Pharmacology and Therapeutics
G Candela, F Romano
No abstract text is available yet for this article.
October 31, 1968: Minerva Ginecologica
C M Ambrus, D H Weintrb, J L Ambrus
No abstract text is available yet for this article.
August 1966: Pediatrics
H Ishida, Y Shimizu, K Imada, T Itagaki, Y Urushidani, R Shimoyama, Y Oono
The subjects here were patients (two males and a female) with the severe acute Guillain-Barre Syndrome admitted to our hospital between September 1987 and December 1988. One case was treated with a double filtration plasmapheresis and two cases were with a immunoadsorption. Of the two extracorponeal thrapeutical methods, the clinical efficacies seemed not to be different however biochemical and serological laboratory data showed prominent differences. For instance the large molecular substances in blood; immunoglobulins, coagulating factors and albumin were reduced in plasma levels by the double filtration plasmapheresis, but not or less by the immunoadsorption...
1991: Biomaterials, Artificial Cells, and Immobilization Biotechnology
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