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https://www.readbyqxmd.com/read/29239850/small-bowel-capsule-endoscopy-may-we-delegate-it-to-nurses
#1
Johann Dreanic, Maximilien Barret, Marion Dhooge, Marianne Gaudric, Sarah Leblanc, Vered Abitbol, Frederic Prat, Stanislas Chaussade, Romain Coriat
AIM: Small bowel capsule endoscopy (CE) is a non-invasive and validated technique allowing the visualization of the small intestine mucosa. It generated more than 40,000 images per examination and induced a long median time of medical reading that may exceed 1 hour. In a transfer of skills' program, the CE reading might be transferred to nurses. We herein evaluate and present a feasibility study of the CE to nurses. METHODS: Nurses experienced in endoscopy were trained for small bowel CE reading, selection and interpretation of pathological images...
November 24, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/29239786/-nephrogenic-fibrosing-dermatosis-from-clinic-to-microscopy
#2
Houcine Yoldez, Blel Ahlem, Ezzeddine Abderrahim, Zeglaoui Faten, Rameh Soumaya
Nephrogenic systemic fibrosis is a rare entity occurred in patients with renal failure. It is related to toxicity to gadolinium, which is used as a contrast agent in magnetic resonance imaging. Clinic manifestations are variable. They begin by a thickening of the skin in the lower limbs and extending to the upper limbs. We report a new case of nephrogenic systemic fibrosis where cutaneous lesions begin in the upper right limb as indurated and ulcerated nodules. The diagnosis is histological.
November 24, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29227042/ex-vivo-confocal-microscopy-features-of-cutaneous-squamous-cell-carcinoma
#3
Daniela Hartmann, Sebastian Krammer, Mario Raphael Bachmann, Leonie Mathemeier, Thomas Ruzicka, Isin Sinem Bagci, Tanja von Braunmühl
BACKGROUND: Rapid microscopic evaluation of cutaneous squamous cell carcinoma (SCC), its grade of differentiation and level of invasiveness would enable better management of patients' therapy. OBJECTIVES: Analyzing specific ex-vivo confocal microscopy criteria whether they can predict diagnosis of invasive SCC vs. carcinoma in situ and poorly differentiated or undifferentiated vs. well and moderately differentiated SCC. METHODS: Ex-vivo confocal images of 102 SCCs in 57 patients were evaluated immediately after excision for the presence of predefined criteria based on confocal and histological knowledge...
December 11, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29221921/ethanol-embolotherapy-for-the-management-of-refractory-chronic-skin-ulcers-caused-by%C3%A2-arteriovenous-malformations
#4
YunBo Jin, Xi Yang, Chen Hua, XiaoXi Lin, Hui Chen, Gang Ma, TianYou Wang, WenXin Yu
PURPOSE: To describe the clinical features and treatment outcomes of ethanol embolotherapy in refractory chronic skin ulcers caused by arteriovenous malformations (AVMs). MATERIALS AND METHODS: From October 2011 to October 2015, 12 patients (5 male; mean age, 26.2 y) with refractory chronic skin ulcers caused by AVMs were treated at a single institution. Ethanol embolotherapy was performed by direct puncture techniques. Needles were directly inserted toward the nidus of the lesion based on imaging analysis...
December 5, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29217439/in-patients-with-severe-peripheral-arterial-disease-revascularization-induced-improvement-in-lower-extremity-ischemia-can-be-detected-by-laser-speckle-contrast-imaging-of-the-fluctuation-in-blood-perfusion-after-local-heating
#5
Sotaro Katsui, Yoshinori Inoue, Yohei Yamamoto, Kimihiro Igari, Toshifumi Kudo, Hiroyuki Uetake
BACKGROUND: We previously reported the utility of the perfusion value fluctuation slope for detecting severe ischemia in the lower limb. Our approach was based on a thermal load test mimicking the well-known physiological reaction termed "cold-induced vasodilation," which is known to occur as a three-phase phenomenon. The slope parameter quantifies the decrease in perfusion values accompanying the relative cooling (third phase) following the transient increase in blood flow (second phase) induced by the applied thermal load...
December 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29216832/a-long-surviving-patient-with-advanced-esophageal-basaloid-squamous-cell-carcinoma-treated-only-with-radiotherapy-case-report-and-literature-review
#6
Toshiya Maebayashi, Naoya Ishibashi, Takuya Aizawa, Masakuni Sakaguchi, Homma Taku, Moritaka Ohhara, Toshirou Takimoto, Yoshiaki Tanaka
BACKGROUND: Esophageal basaloid squamous cell carcinoma (EBSCC) is a rare malignant disease. Advanced EBSCC (AEBSCC) has a poorer prognosis than the more common esophageal squamous cell carcinoma, but no treatment policy has yet been established. This is the first reported case with AEBSCC treated only with radiotherapy. Thus, our long-surviving patient merits consideration. We therefore reviewed cases with the same stage of AEBSCC for further investigation. CASE PRESENTATION: An 85-year-old man with a chief complaint of difficulty swallowing foods was diagnosed with AEBSCC, cT3N1M0, stage III, by thorough examination...
December 8, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29196307/methotrexate-associated-lymphoproliferative-disease-with-multiple-pulmonary-nodules-in-a-patient-with-rheumatoid-arthritis
#7
Wei-Fu Lai, Yen-Po Chin, Chih-Wei Liu, Chang-Youh Tsai
A 62-year-old woman with rheumatoid arthritis and secondary Sjögren's syndrome took methotrexate (MTX) 5 mg three times a week regularly but gradually developed an intermittent fever, oral ulcers and productive cough with mucopurulent sputum for about 2 weeks. Image study found multiple nodular lesions and lymphadenopathies in bilateral lungs. Empirical antibiotics for 1 week failed to alleviate the fever. A transbronchial biopsy in the right fourth bronchus showed infiltration of abnormally enlarged lymphoid cells with a surface marker of CD20, some of which also stained positively in situ with Epstein-Barr virus-encoded small RNA and some CD3(+) cells...
December 1, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29196115/imaging-manifestations-of-behcet-s-disease-key-considerations-and-major-features
#8
REVIEW
Ghazaleh Mehdipoor, Fereydoun Davatchi, Hadi Ghoreishian, Abbas Arjmand Shabestari
Behcet's disease is an autoimmune disease most commonly seen in the Middle East. Although primarily known with painful oral and genital ulcers, it can lead to vasculitis. Therefore, several associated complications such as thrombotic syndromes, aneurysmal arterial disease may arise. In many cases, it might be difficult to make the diagnosis purely based on clinical grounds; however, imaging plays an important role for both diagnosis and assessment of the disease's complications. We provide a comprehensive review of the most notable imaging findings of Behcet's disease...
November 21, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29193858/exophiala-phaeomuriformis-keratitis-in-a-subarctic-climate-region-a-case-report
#9
André Vicente, Fátima Pedrosa Domellöf, Berit Byström
PURPOSE: To report a case of Exophiala phaeomuriformis mycotic keratitis in a patient from a subarctic climate region. Dematiaceous fungi (black yeasts) have been gaining importance as corneal keratitis and ulcer causative agents in certain regions, but no cases have been described in Scandinavia. METHODS: Case report of a patient with a persistent corneal erosion that eventually presented a brown-pigmented infiltrate. The patient had a history of several months of topical therapy comprising medication for glaucoma, corticosteroids and antibiotics...
November 29, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29181848/linked-color-imaging-identified-uc-associated-colorectal-cancer-a-case-report
#10
Tadakazu Hisamatsu, Akiko Ohno, Tomohiro Chiba
Ulcerative colitis (UC) associated colorectal cancer (CRC) is an important issue in long-term management of patients with UC. Lesions with chronic inflammatory mucosa as background may often be difficult to identify even by endoscopic observation. Traditionally, a random biopsy strategy was recommended, but problems with patient compliance, increased burden on endoscopic staff and pathologists, were left. This article is protected by copyright. All rights reserved.
November 27, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29164658/successful-treatment-of-raynaud-s-phenomenon-and-digital-ulcers-in-systemic-sclerosis-patients-with-botulinum-toxin-b-injection-assessment-of-peripheral-vascular-disorder-by-angiography-and-dermoscopic-image-of-nail-fold-capillary
#11
Sei-Ichiro Motegi, Akiko Sekiguchi, Shintaro Saito, Hirohisa Ishibuchi, Chikako Kishi, Masahito Yasuda, Osamu Ishikawa
We recently identified the efficacy and safety of a botulinum toxin (BTX)-A/B in Raynaud's phenomenon (RP) and digital ulcers (DU) in Japanese patients with systemic sclerosis (SSc). Detailed assessments of peripheral vascular disorder using angiography and dermoscopic images of nail fold capillaries have not been performed previously. This study aimed to evaluate the effect of BTX-B on SSc-associated peripheral vascular disorder. Two SSc patients who suffered with RP and DU were treated with a BTX-B injection, and thereafter the symptoms of RP were improved and DU healed in both patients...
November 22, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/29148933/surgical-strategies-for-the-treatment-of-os-odontoideum-with-atlantoaxial-dislocation
#12
Xinghuo Wu, Kirkham B Wood, Yong Gao, Shuai Li, Jing Wang, Ting Ge, Boming Zhao, Zengwu Shao, Shuhua Yang, Cao Yang
OBJECTIVE This study aimed to compare the clinical results of using posterior fixation and fusion with or without anterior decompression to treat os odontoideum with atlantoaxial dislocation. METHODS Twenty-five consecutive patients with os odontoideum were included in this study. Sixteen patients with reducible atlantoaxial dislocation were treated by single-level posterior fusion and stabilization; the other 9 were treated with posterior fusion and stabilization combined with transoral decompression. Pre- and postoperative CT scans and MR images were obtained...
November 17, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29146893/von-hippel-lindau-disease-with-multi-organ-involvement-a-case-report-and-8-year-clinical-course-with-follow-up
#13
Ali Yaghobi Joybari, Payam Azadeh
BACKGROUND Von Hippel-Lindau (VHL) disease is a rare autosomal dominant syndrome manifested by a spectrum of benign and malignant tumors.  CASE REPORT The patient presented here was a 31-year-old female with unremarkable family history who presented initially complaining of intermittent abdominal pain. Abdominal CT scan revealed an inhomogeneous solid mass (13×9×7 cm) originating from the tail of the pancreas with splenic and gastric invasion as well as several pancreatic cysts. A nucleotide scan showed left adrenal involvement...
November 17, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29137078/successful-treatment-of-ovarian-cancer-with-apatinib-combined-with-chemotherapy-a-case-report
#14
Mingzi Zhang, Zhongkai Tian, Yehong Sun
RATIONALE: The standard treatment for ovarian cancer is chemotherapy with 2 drugs (taxanes and platinum drugs). However, the traditional combination of the 2 drugs has many adverse effects (AEs) and the cancer cells will quickly become resistant to the drugs. Apatinib is a small-molecule antiangiogenic agent which has shown promising therapeutic effects against diverse tumor types, but it still remains unknown whether apatinib has an antitumor effect in patients with ovarian cancer. Herein, we present a successfully treated case of ovarian cancer using chemotherapy and apatinib, in order to demonstrate the effectiveness of this new combined regimen in ovarian cancer...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29131746/topical-oxygen-therapy-promotes-the-healing-of-chronic-diabetic-foot-ulcers-a-pilot-study
#15
P D Hayes, N Alzuhir, G Curran, I M Loftus
OBJECTIVE: Interventions that can heal or reduce diabetic foot ulcer (DFU) size may reduce the incidence of infection and amputation, and reduce associated social and economic costs. Many chronic wounds exhibit a degree of hypoxia and this leads to a reduction in healing processes including cell division and differentiation, angiogenesis, infection prevention, and collagen production. The aim of this pilot study was to assess the effects of a device supplying continuous oxygen ambulatory therapy on healing in chronic DFUs...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29110055/reproducible-imaging-features-of-biologically-aggressive-gastrointestinal-stromal-tumors-of-the-small-bowel
#16
Francisco J Maldonado, Shannon P Sheedy, Veena R Iyer, Stephanie L Hansel, David H Bruining, Cynthia H McCollough, William S Harmsen, John M Barlow, Joel G Fletcher
PURPOSE: To identify reproducible CT imaging features of small bowel gastrointestinal stromal tumors (GIST) that are associated with biologic aggressiveness. METHODS: Patients with histologically proven small bowel GISTs and CT enterography or abdominopelvic CT were included. Biologic aggressiveness was established based on initial histologic grading (very low risk to malignant), with "malignant" assigned if recurrence or metastases developed subsequently. CT exams were independently evaluated by three gastrointestinal radiologists for tumor size, growth pattern, enhancement, tumor borders, necrosis, calcification, ulceration, multiplicity, internal air or enteric contrast, nodal metastasis, liver metastasis, peritoneal metastasis, ascites, and draining vein size...
November 6, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29095257/efficacy-and-safety-of-bevacizumab-treatment-for-refractory-brain-edema-case-report
#17
Xiangying Meng, Rugang Zhao, Ge Shen, Dapeng Dong, Lijuan Ding, Shikai Wu
OBJECTIVE: This retrospective study investigated the efficacy and safety of bevacizumab treatment for refractory brain edema. METHODS: Between March 2009 and December 2015, bevacizumab was used to treat 59 cases of brain metastatic patients with refractory brain edema. The median dose of bevacizumab was 4.68 mg/kg (range 2.8-6.52 mg/kg). The clinical-pathological data, the efficacy, and the side effects of bevacizumab were recorded. Magnetic resonance imaging (MRI) was performed before and after bevacizumab treatment...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29089826/post-ischemic-bowel-stricture-ct-features-in-eight-cases
#18
Jin Sil Kim, Hyun Jin Kim, Seung-Mo Hong, Seong Ho Park, Jong Seok Lee, Ah Young Kim, Hyun Kwon Ha
OBJECTIVE: To investigate the characteristic radiologic features of post-ischemic stricture, which can then be implemented to differentiate that specific disease from other similar bowel diseases, with an emphasis on computed tomography (CT) features. MATERIALS AND METHODS: Eight patients with a diagnosis of ischemic bowel disease, who were also diagnosed with post-ischemic stricture on the basis of clinical or pathologic findings, were included. Detailed clinical data was collected from the available electronic medical records...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29074638/association-between-carotid-plaque-features-on-cta-and-cerebrovascular-ischemia-a-systematic-review-and-meta-analysis
#19
H Baradaran, K Al-Dasuqi, A Knight-Greenfield, A Giambrone, D Delgado, E J Ebani, H Kamel, A Gupta
BACKGROUND: CTA is a widely available imaging examination that may allow the evaluation of high-risk carotid plaque features. PURPOSE: Our aim was to evaluate the association between specific carotid plaque features on CTA and ipsilateral cerebrovascular ischemia. DATA SOURCES: We performed a systematic review of Ovid MEDLINE, Ovid Embase, Scopus, and the Cochrane Library from inception to March 2016 for articles that evaluated the relationship between CTA-detected carotid plaque features and ischemic events, defined as ipsilateral ischemic stroke or transient ischemic attack...
October 26, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29074110/evaluation-of-a-new-model-of-hind-limb-ischemia-in-rabbit
#20
Costantino Del Giudice, Gabriel Ifergan, Guillaume Goudot, Valerie Bellamy, Emmanuel Messas, Olivier Clement, Patrick Bruneval, Philippe Menasche, Marc Sapoval
OBJECTIVE: Various animal models of critical limb ischemia have been developed in the past. However, there is no animal model that can undergo endovascular treatment, while providing reproducible true critical limb ischemia with arterial ulcers and rest pain. We evaluated the efficacy of a new model of rabbit hindlimb ischemia created through a percutaneous approach using embolization with calibrated particles. METHODS: Through a percutaneous transauricular artery approach and selective catheterization of the superficial femoral artery, embolization of distal limb vessels was performed using a mixture of 300- to 500-μm calibrated microparticles (Embosphere, Merit Medical, Salt Lake City, Utah), saline solution, and iodine contrast...
October 23, 2017: Journal of Vascular Surgery
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