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https://www.readbyqxmd.com/read/28101306/essential-role-of-small-bowel-capsule-endoscopy-in-reclassification-of-colonic-inflammatory-bowel-disease-type-unclassified
#1
Sara Monteiro, Francisca Dias de Castro, Pedro Boal Carvalho, Bruno Rosa, Maria João Moreira, Rolando Pinho, Miguel Mascarenhas Saraiva, José Cotter
AIM: To evaluate the role of small bowel capsule endoscopy (SBCE) on the reclassification of colonic inflammatory bowel disease type unclassified (IBDU). METHODS: We performed a multicenter, retrospective study including patients with IBDU undergoing SBCE, between 2002 and 2014. SBCE studies were reviewed and the inflammatory activity was evaluated by determining the Lewis score (LS). Inflammatory activity was considered significant and consistent with Crohn's disease (CD) when the LS ≥ 135...
January 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28099579/factors-for-determining-dental-anxiety-in-preschool-children-with-severe-dental-caries
#2
Jenny Abanto, Evelyn Alvarez Vidigal, Thiago Saads Carvalho, Stella Núbia Coelho de Sá, Marcelo Bönecker
The aim of this study was to assess the clinical and socioeconomic indicators associated with dental anxiety in preschool children with severe dental caries. A total of 100 children between 3 and 5 years of age were selected during a dental screening procedure. The selection criteria were having at least one tooth with dental caries and a visible pulpal involvement, ulceration, fistula, and abscess (PUFA) index of ≥1 in primary teeth. Before the clinical examination or any treatment procedure was performed, we evaluated the children's dental anxiety using the Facial Image Scale (FIS)...
January 16, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28099545/cutaneous-adnexal-carcinoma-with-apocrine-differentiation
#3
Vikram Prasad, Wynn H Kao, Grace F Kao
Primary cutaneous apocrine carcinomas are uncommon malignant neoplasms that can be difficult, if not impossible, to distinguish histologically from metastatic breast carcinomas. We present the case of a 71-year-old man with a 5-year history of extensive ulcerated plaques on the posterior neck and posterior scalp. Biopsy revealed a poorly differentiated infiltrating adenocarcinoma consistent with either primary cutaneous apocrine carcinoma or occult metastatic breast carcinoma. Immunohistochemical analysis demonstrated positive staining for cytokeratin (CK) 7, estrogen receptor, and progesterone receptor, and negative staining for p63, podoplanin, CK20, and thyroid transcription factor 1...
December 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28093600/vascular-patterns-in-cutaneous-ulcerated-basal-cell-carcinoma-a-retrospective-blinded-study-including-dermoscopy
#4
Nicola Arpaia, Angela Filoni, Domenico Bonamonte, Giuseppe Giudice, Margherita Fanelli, Michelangelo Vestita
The aim of this retrospective study was to determine the type and prevalence of vascular patterns in the ulcerated and non-ulcerated portions of histologically proven basal cell carcinomas (BCCs) and correlate them with other dermoscopic and clinical features, including the clinically supposed diagnosis. Three authors retrospectively collected 156 clinical and 156 dermoscopic digital images of ulcerated BCCs (histologically confirmed); each image was blindly evaluated by 2 other authors, who did not know the histological diagnosis...
January 17, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28092221/tuberculosis-mimicking-primary-systemic-vasculitis-not-to-be-missed
#5
Ankit Jain, Durga Prasanna Misra, A Ramesh, Debdatta Basu, Vikramraj K Jain, Vir Singh Negi
Infections are an important differential diagnosis in patients presenting with features of systemic vasculitis. We report a young lady with constitutional features, leg ulcers, digital gangrene and absent peripheral pulses with cervical adenopathy. Chest imaging revealed multiple necrotic lung lesions and involvement of left subclavian artery at its origin from the aorta, Histopathology from cervical lymph nodes showed multiple caseated lymph nodes, which in the context of a positive Mantoux test led us to diagnose tuberculosis and institute appropriate therapy...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28088968/-para-neoplastic-autoimmune-multi-organ-syndrome-associated-with-follicular-lymphoma-a-case-report-and-literature-review
#6
D Chen, C Y Lin, X Han, B Chen, Z H Lu, X Y Chang, M H Duan
Objective: To broaden our knowledge of para-neoplastic autoimmune multi-organ syndrome (PAMS). Methods: A patient with PAMS associated with follicular lymphoma and bronchiolitis obliterans treated in our hospital was retrospectively analyzed and the clinical features of PAMS were reviewed. Results: A 49-year-old female patient suffered from painful ulcers in the oral cavity and vagina, dry cough and dyspnea. Imaging examinations suggested multiple lymph node enlargements. Inguinal lymph node biopsy revealed follicular lymphoma...
December 14, 2016: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/28086892/pressure-ulcer-image-segmentation-technique-through-synthetic-frequencies-generation-and-contrast-variation-using-toroidal-geometry
#7
Ortiz P David, Daniel Sierra-Sosa, Begoña García Zapirain
BACKGROUND: Pressure ulcers have become subject of study in recent years due to the treatment high costs and decreased life quality from patients. These chronic wounds are related to the global life expectancy increment, being the geriatric and physical disable patients the principal affected by this condition. Injuries diagnosis and treatment usually takes weeks or even months by medical personel. Using non-invasive techniques, such as image processing techniques, it is possible to conduct an analysis from ulcers and aid in its diagnosis...
January 6, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28076252/a-clinical-aid-for-detecting-skin-cancer-the-triage-amalgamated-dermoscopic-algorithm-tada
#8
T Rogers, M L Marino, S W Dusza, S Bajaj, R P Usatine, M A Marchetti, A A Marghoob
PURPOSE: Family physicians (FPs) frequently evaluate skin lesions but may not have the necessary training to accurately and confidently identify lesions that require skin biopsy or specialist referral. We evaluated the diagnostic performance of a new, simplified dermoscopy algorithm for skin cancer detection. METHODS: In this cross-sectional, observation study, attendees of a dermoscopy course evaluated 50 polarized dermoscopy images of skin lesions (27 malignant and 23 benign) using the Triage Amalgamated Dermoscopic Algorithm (TADA)...
November 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28071288/vulnerable-carotid-plaque-imaging-and-histopathology-without-a-dedicated-mri-receiver-coil
#9
Laura A Fitzpatrick, Nadav Berkovitz, Marlise P Dos Santos, Nevin Majeed, Rafael Glikstein, Santanu Chakraborty, John P Veinot, Grant Stotts, Alain Berthiaume, Robert Chatelain
Stroke is associated with vulnerable carotid artery plaques showing specific histopathologic features, namely a lipid-rich necrotic core, intraplaque hemorrhage, ulceration, and thin fibrous cap. While ultrasound and computed tomography (CT) can identify carotid plaques and determine the extent of stenosis, magnetic resonance imaging (MRI) provides further information regarding plaque composition and morphology. In this feasibility study, three patients with symptomatic, moderately stenosed plaques were imaged with CT angiography (CTA) and MRI (3T and 1...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28070658/getting-the-gist-a-pictorial-review-of-the-various-patterns-of-presentation-of-gastrointestinal-stromal-tumors-on-imaging
#10
REVIEW
Dominic Scola, Lawrence Bahoura, Alexander Copelan, Ali Shirkhoda, Farnoosh Sokhandon
Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the gastrointestinal tract, are a relatively recently described entity. Most exhibit a mutated tyrosine kinase receptor gene and in some capacity are treated by tyrosine kinase inhibitors. GISTs can occur across the age spectrum but are more common in patients older than 40 years. They exhibit a wide range of clinical presentations and imaging characteristics. All patterns of enhancement on contrast enhanced computed tomography (CECT) can be seen with GISTs, including hypoenhancing, isoenhancing, and hyperenhancing tumors...
January 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28065614/cerebral-venous-sinus-thrombosis-presenting-feature-of-systemic-lupus-erythematosus
#11
Rajesh Kumar Singh, Sanjeev Kumar Bhoi, Jayantee Kalita, Usha Kant Misra
BACKGROUND: CVST (cerebral venous sinus thrombosis) may sometimes be associated with autoimmune disorders that require specific treatment. The clinical and magnetic resonance imaging (MRI) findings of systemic lupus erythematosus (SLE) patients with CVST are presented and contrasted with CVST without SLE. METHODS: Consecutive patients with CVST admitted in neurology service during 2012-2016 were included. The diagnosis of CVST was confirmed by MR venography or digital subtraction angiography...
January 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28063144/undifferentiated-carcinoma-of-the-ampulla-of-vater
#12
Misuzu Yamada, Daisuke Furukawa, Naoki Yazawa, Hideki Izumi, Yoshihito Masuoka, Taro Mashiko, Yoshiaki Kawaguchi, Masami Ogawa, Yohei Kawashima, Tetsuya Mine, Kenichi Hirabayashi, Toshio Nakagohri
Undifferentiated carcinoma of the ampulla of Vater is a rare disease with unclear and clinical characteristics and prognosis. Here, we report the case of a 61-year-old man with undifferentiated carcinoma of the ampulla of Vater. He presented to our hospital with an increase in hepatobiliary system enzymes that was detected during a health check-up. Imaging and endoscopy demonstrated a tumor with ulcer in the ampulla of Vater, which was diagnosed as a carcinoma by biopsy. No distant metastasis was observed. Subtotal stomach-preserving pancreaticoduodenectomy was performed...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28060277/inducing-ischemia-reperfusion-injury-in-the-mouse-ear-skin-for-intravital-multiphoton-imaging-of-immune-responses
#13
Chi Ching Goh, Jackson LiangYao Li, David Becker, Wolfgang Weninger, Veronique Angeli, Lai Guan Ng
Ischemia-reperfusion injury (IRI) occurs when there is transient hypoxia due to the obstruction of blood flow (ischemia) followed by a subsequent re-oxygenation of the tissues (reperfusion). In the skin, ischemia-reperfusion (IR) is the main contributing factor to the pathophysiology of pressure ulcers. While the cascade of events leading up to the inflammatory response has been well studied, the spatial and temporal responses of the different subsets of immune cells to an IR injury are not well understood...
December 22, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28058450/collagenous-sprue-cross-sectional-imaging-a-comparative-blinded-study
#14
Badr Al-Bawardy, Shannon P Sheedy, Michelle B Herberts, Joseph A Murray, Alberto Rubio-Tapia, Elizabeth Rajan, David H Bruining, Stephanie L Hansel, John M Barlow, Joel G Fletcher, Jeff L Fidler
PURPOSE: Collagenous sprue (CS) is a rare enteropathy characterized by villous atrophy and a thickened subepithelial collagen band. The aim of this study is to describe the cross-sectional imaging findings of CS. METHODS: A case-control, retrospective study with cases of all CS patients from January 2000 to 2015 was performed. Inclusion criteria were (1) Histopathologic diagnosis and (2) Imaging with computed tomography abdomen/pelvis (CT A/P), CT enterography (CTE), or magnetic resonance enterography within 6 months of small bowel (SB) biopsy...
January 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28058449/impact-of-ct-enterography-on-the-diagnosis-of-small-bowel-gastrointestinal-stromal-tumors
#15
Rogerio N Vasconcelos, Steven G Dolan, John M Barlow, Michael L Wells, Shannon P Sheedy, Jeff L Fidler, Stephanie Hansel, Scott Harmsen, Joel G Fletcher
OBJECTIVE: Our purpose is to determine the impact of CT enterography on small bowel gastrointestinal stromal tumor (GIST) detection and biologic aggressiveness, and to identify any imaging findings that correlate with biologic aggressiveness. METHODS: Records of patients with histologically confirmed small bowel GISTs who underwent CT imaging were reviewed. Biologic aggressiveness was based on initial histologic grading (very low, low, intermediate, high grade; or malignant), with upgrade to malignant category if local or distant metastases developed during clinical follow-up...
January 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28053300/a-medical-thermal-imaging-device-for-the-prevention-of-diabetic-foot-ulceration
#16
Graham Machin, Aaron Whittam, Suhail Ainarkar, John Allen, John Bevans, Michael Edmonds, Ben Kluwe, Audrey Macdonald, Nina Petrova, Peter Plassmann, Francis Ring, Leon Rogers, Rob Simpson
In this paper a description is given of the development, characterisation and first results of a thermal imaging device aimed at significantly reducing the incidence of diabetic foot ulceration (DFU). These devices will be used in three clinical centres and in two preliminary clinical trials. The first will be on healthy volunteers to set a robust baseline for the overall research aims and the second on >100 patients at high risk of DFU. In the second phase of the project the objective is to demonstrate significant reduction in the incidence of DFU through a comparison of the results of standard care of high risk feet with standard care plus thermal imaging...
January 5, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28045777/capillary-flow-rates-in-the-duodenum-of-pediatric-ulcerative-colitis-patients-are-increased-and-unrelated-to-inflammation
#17
Deenaz Zaidi, Lucas Churchill, Hien Q Huynh, Matthew W Carroll, Rabin Persad, Eytan Wine
BACKGROUND: Inflammatory bowel diseases (IBD), including Crohn disease (CD) and ulcerative colitis (UC), are chronic pediatric disorders. Changes in vasculature are described in IBD but these could be secondary to inflammation and the role in pathogenesis is poorly understood. Assessing circulatory changes in typically unaffected sites in IBD (e.g., duodenum), when inflammation is absent, can identify vascular changes associated with pathogenesis. AIM: To measure capillary flow rates in duodenal mucosa using probe-based confocal laser endomicroscopy (pCLE) during endoscopy in children with IBD...
December 30, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28045023/meta-analytic-bayesian-model-for-differentiating-intestinal-tuberculosis-from-crohn-s-disease
#18
REVIEW
Julajak Limsrivilai, Andrew B Shreiner, Ananya Pongpaibul, Charlie Laohapand, Rewat Boonanuwat, Nonthalee Pausawasdi, Supot Pongprasobchai, Sathaporn Manatsathit, Peter D R Higgins
OBJECTIVES: Distinguishing intestinal tuberculosis (ITB) from Crohn's disease (CD) is difficult, although studies have reported clinical, endoscopic, imaging, and laboratory findings that help to differentiate these two diseases. We aimed to produce estimates of the predictive power of these findings and construct a comprehensive model to predict the probability of ITB vs. CD. METHODS: A systematic literature search for studies differentiating ITB from CD was conducted in MEDLINE, PUBMED, and EMBASE from inception until September 2015...
January 3, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28043985/in-vivo-confocal-microscopy-appearance-of-fusarium-and-aspergillus-species-in-fungal-keratitis
#19
Jaya Devi Chidambaram, Namperumalsamy Venkatesh Prajna, Natasha Larke, David Macleod, Palepu Srikanthi, Shruti Lanjewar, Manisha Shah, Prajna Lalitha, Shanmugam Elakkiya, Matthew J Burton
BACKGROUND: Clinical outcomes in fungal keratitis vary between Fusarium and Aspergillus spp, therefore distinguishing between species using morphological features such as filament branching angles, sporulation along filaments (adventitious sporulation) or dichotomous branching may be useful. In this study, we assessed these three features within Heidelberg Retina Tomograph 3 in vivo confocal microscopy (IVCM) images from culture-positive Fusarium and Aspergillus spp keratitis participants...
January 2, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28034631/emergency-endovascular-management-of-acute-thoracic-aortic-pathology-a-safe-and-feasible-option
#20
Z Ahmed, S M McHugh, A Elmallah, M P Colgan, A O'Callaghan, S M O'Neill, P Madhavan, Z Martin
Endovascular repair has revolutionised the emergency treatment of thoracic aortic disease. We report our 10 year experience using this treatment in emergency cases. A prospectively maintained vascular database was analysed. Patients' medical records and CT images stored on the hospital PACS system were also reviewed. Statistical analysis was done using IBM SPSS V21. There were a total of 59 thoracic aortic stenting procedures of which 33 (60% males with a mean age of 58 yrs) were performed for emergency thoracic pathologies: traumatic transection (n = 10), ruptured aneurysm (n = 6), non-traumatic dissection (n = 8) and penetrating aortic ulcer (n = 9)...
December 27, 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
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