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https://www.readbyqxmd.com/read/28732281/epileptic-seizure-detection-in-eegs-signals-based-on-the-weighted-visibility-graph-entropy
#1
Zeynab Mohammadpoory, Mahda Nasrolahzadeh, Javad Haddadnia
PURPOSE: Epileptic seizure detection has been a complex task for both researchers and specialist in that the assessment of epilepsy is difficult because, electroencephalogram (EEG) signals are chaotic and non-stationary. METHOD: This paper proposes a new method based on weighted visibility graph entropy (WVGE) to identify seizure from EEG signals. Single channel EEG signals are mapped onto the WVGs and WVGEs are calculated from these WVGs. Then some features are extracted of WVGEs and given to classifiers to investigate the performance of these features to classify the brain signals into three groups of normal (healthy), seizure free (interictal) and during a seizure (ictal) groups...
July 11, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28731769/first-principles-prediction-of-spin-polarized-multiple-dirac-rings-in-manganese-fluoride
#2
Yalong Jiao, Fengxian Ma, Chunmei Zhang, John Bell, Stefano Sanvito, Aijun Du
Spin-polarized materials with Dirac features have sparked great scientific interest due to their potential applications in spintronics. But such a type of structure is very rare and none has been fabricated. Here, we investigate the already experimentally synthesized manganese fluoride (MnF_{3}) as a novel spin-polarized Dirac material by using first-principles calculations. MnF_{3} exhibits multiple Dirac cones in one spin orientation, while it behaves like a large gap semiconductor in the other spin channel...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731764/phase-tuned-entangled-state-generation-between-distant-spin-qubits
#3
R Stockill, M J Stanley, L Huthmacher, E Clarke, M Hugues, A J Miller, C Matthiesen, C Le Gall, M Atatüre
Quantum entanglement between distant qubits is an important feature of quantum networks. Distribution of entanglement over long distances can be enabled through coherently interfacing qubit pairs via photonic channels. Here, we report the realization of optically generated quantum entanglement between electron spin qubits confined in two distant semiconductor quantum dots. The protocol relies on spin-photon entanglement in the trionic Λ system and quantum erasure of the Raman-photon path information. The measurement of a single Raman photon is used to project the spin qubits into a joint quantum state with an interferometrically stabilized and tunable relative phase...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731261/structural-insights-for-the-borates-with-anion-templated-open-framework-configuration-asymmetric-k2bab16o26-vs-centrosymmetric-k3csb20o32-and-na2m2nb18o30-m-rb-cs-n-ba-pb
#4
Miriding Mutailipu, Min Zhang, Xin Su, Zhihua Yang, Yanna Chen, Shilie Pan
Five new mixed-metal borates, namely, K2BaB16O26, K3CsB20O32, Na2Cs2BaB18O30, Na2Rb2PbB18O30, and Na2Cs2PbB18O30 were synthesized using the high-temperature solution method. Those structures were characterized by single-crystal X-ray diffraction, and the B-O configurations of them are shown to feature complicated three-dimensional (3D) open-framework structures with different types of channels. For all the five compounds, the frameworks can be reduced into four-connected (4-c) uninodal net with sra-, dia- and nbo-type topology by assigning the [B5O10]5- and [B3O7]5- clusters as basic nodes...
July 21, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28731049/composite-hemangioendothelioma-with-neuroendocrine-marker-expression-an-aggressive-variant
#5
Kyle D Perry, Alyaa Al-Lbraheemi, Brian P Rubin, Jin Jen, Hongzheng Ren, Jin Sung Jang, Asha Nair, Jaime Davila, Stefan Pambuccian, Andrew Horvai, William Sukov, Henry D Tazelaar, Andrew L Folpe
Aberrant expression of neuroendocrine markers is extremely rare in endothelial neoplasms, with only a single report describing three cases. Although originally classified as conventional angiosarcoma, further assessment of these tumors revealed a strikingly composite morphology composed of retiform and epithelioid elements reminiscent of composite hemangioendothelioma, a rare subtype of hemangioendothelioma. To further investigate these findings, available materials from 11 morphologically distinctive endothelial tumors showing neuroendocrine marker expression were retrieved from our archives...
July 21, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28730802/sensing-single-molecule-penetration-into-nanopores-pushing-the-time-resolution-to-the-diffusion-limit
#6
Igor Bodrenko, Jiajun Wang, Samuele Salis, Mathias Winterhalter, Matteo Ceccarelli
To quantify small molecule penetration into and eventually permeation through nanopores, we applied an improved excess-noise analysis of the ion current fluctuation caused by entering molecules. The kinetic parameters of substrate entry and leave are derived from a two-state Markov model, analyzing the substrate concentration depen- dence of the average ion current and its variance. Including filter corrections allows one to detect the transition rates beyond the cutoff frequency, fc, of the instrumental ion-current filter...
July 21, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28729872/plc-mediated-signaling-pathway-in-pollen-tubes-regulates-the-gametophytic-self-incompatibility-of-pyrus-species
#7
Haiyong Qu, Yaqin Guan, Yongzhang Wang, Shaolin Zhang
Among the Rosaceae species, the gametophytic self-incompatibility (GSI) is controlled by a single multi-allelic S locus, which is composed of the pistil-S and pollen-S genes. The pistil-S gene encodes a polymorphic ribonuclease (S-RNase), which is essential for identifying self-pollen. However, the S-RNase system has not been fully characterized. In this study, the self-S-RNase inhibited the Ca(2+)-permeable channel activity at pollen tube apices and the selectively decreased phospholipase C (PLC) activity in the plasma membrane of Pyrus pyrifolia pollen tubes...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28729840/cardiac-subtype-specific-modeling-of-kv1-5-ion-channel-deficiency-using-human-pluripotent-stem-cells
#8
Maike Marczenke, Ilaria Piccini, Isabella Mengarelli, Jakob Fell, Albrecht Röpke, Guiscard Seebohm, Arie O Verkerk, Boris Greber
The ultrarapid delayed rectifier K(+) current (IKur), mediated by Kv1.5 channels, constitutes a key component of the atrial action potential. Functional mutations in the underlying KCNA5 gene have been shown to cause hereditary forms of atrial fibrillation (AF). Here, we combine targeted genetic engineering with cardiac subtype-specific differentiation of human induced pluripotent stem cells (hiPSCs) to explore the role of Kv1.5 in atrial hiPSC-cardiomyocytes. CRISPR/Cas9-mediated mutagenesis of integration-free hiPSCs was employed to generate a functional KCNA5 knockout...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28729686/ultralow-voltage-operation-of-biologically-assembled-all-carbon-nanotube-nanomesh-transistors-with-ion-gel-gate-dielectrics
#9
Hye-Hyeon Byeon, Kein Kim, Woong Kim, Hyunjung Yi
The demonstration of field-effect transistors (FETs) based entirely on single-walled carbon nanotubes (SWNTs) would enable the fabrication of high-on-current, flexible, transparent and stretchable devices owing to the excellent electrical, optical, and mechanical properties of SWNTs. Fabricating all-SWNT-based FETs via simple solution process, at room temperature and without using lithography and vacuum process could further broaden the applicability of all-SWNT-FETs. In this work, we report on biologically assembled all SWNT-based transistors and demonstrate that ion-gel-gated network structures of unsorted SWNTs assembled using a biological template material enabled operation of SWNT-based transistors at a very low voltage...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729645/nano-antenna-enhanced-two-focus-fluorescence-correlation-spectroscopy
#10
Lutz Langguth, Agata Szuba, Sander A Mann, Erik C Garnett, Gijsje H Koenderink, A Femius Koenderink
We propose two-focus fluorescence correlation spectroscopy (2fFCS) on basis of plasmonic nanoantennas that provide distinct hot spots that are individually addressable through polarization, yet lie within a single diffraction limited microscope focus. The importance of two-focus FCS is that a calibrated distance between foci provides an intrinsic calibration to derive diffusion constants from measured correlation times. Through electromagnetic modelling we analyze a geometry of perpendicular nanorods, and their inverse, i...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728815/the-structural-basis-for-sensing-by%C3%A2-the-piezo1-protein
#11
W Li, N Gao, M Yang
Mechanotransduction is one of the processes by which cells sense and convert mechanical stimuli into biological signals. Experimental data from various species have revealed crucial roles for mechanotransduction in organ development and a plethora of physiological activities. Piezo proteins have recently been identified as the long-sought-after mechanically activated cation channels in eukaryotes. The architecture of mouse Piezo1 (mPiezo1) channel determined by cryoelectron microscopic single-particle analysis at medium resolution yielded important insights into the mechanical force sensing mechanism...
2017: Current Topics in Membranes
https://www.readbyqxmd.com/read/28727917/a-3d-printed-portable-optical-sensing-platform-for-smartphones-capable-of-detecting-the-herbicide-2-4-dichlorophenoxyacetic-acid
#12
Yijia Wang, Mohamed Maarouf Ali Zeinhom, Mingming Yang, Rongrong Sun, Shengfu Wang, Jordan N Smith, Charles Timchalk, Lei Li, Yuehe Lin, Dan Du
Onsite rapid detection of herbicide and herbicide residuals in environmental and biological specimens is important for agriculture, environment, food safety, and health care. Traditional method for herbicide detection requires expensive laboratory equipment and a long turn-round time. In this work, we developed a single-stripe microliter plate smartphone colorimetric device for rapid and low-cost in-field test. This portable smartphone platform is capable of screening 8 samples in a microplate single-stripe...
July 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28727559/a-microfluidic-cytometer-for-complete-blood-count-with-a-3-2-megapixel-1-1-%C3%AE-m-pitch-super-resolution-image-sensor-in-65-nm-bsi-cmos
#13
Xu Liu, Xiwei Huang, Yu Jiang, Hang Xu, Jing Guo, Han Wei Hou, Mei Yan, Hao Yu
Based on a 3.2-Megapixel 1.1- μm-pitch super-resolution (SR) CMOS image sensor in a 65-nm backside-illumination process, a lens-free microfluidic cytometer for complete blood count (CBC) is demonstrated in this paper. Backside-illumination improves resolution and contrast at the device level with elimination of surface treatment when integrated with microfluidic channels. A single-frame machine-learning-based SR processing is further realized at system level for resolution correction with minimum hardware resources...
July 18, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28727182/probing-anisotropic-thermal-conductivity-of-transition-metal-dichalcogenides-mx2-m-mo-w-and-x-s-se-using-time-domain-thermoreflectance
#14
Puqing Jiang, Xin Qian, Xiaokun Gu, Ronggui Yang
Transition metal dichalcogenides (TMDs) are a group of layered 2D semiconductors that have shown many intriguing electrical and optical properties. However, the thermal transport properties in TMDs are not well understood due to the challenges in characterizing anisotropic thermal conductivity. Here, a variable-spot-size time-domain thermoreflectance approach is developed to simultaneously measure both the in-plane and the through-plane thermal conductivity of four kinds of layered TMDs (MoS2 , WS2 , MoSe2 , and WSe2 ) over a wide temperature range, 80-300 K...
July 20, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28727007/best-management-practices-for-newly-weaned-calves-for-improved-health-and-well-being
#15
B K Wilson, C J Richards, D L Step, C R Krehbiel
Morbidity and mortality in newly weaned calves resulting from bovine respiratory disease (BRD) continue to be the most significant problems facing the beef industry. Morbidity attributed to BRD accounts for approximately 75% of total feedlot morbidity. Several experiments have documented the economic impacts of BRD. Direct costs attributable to BRD include death loss, treatment and labor costs, and prevention costs, while indirect costs associated with BRD include decreased growth performance and feed efficiency, increased days on feed, and decreased carcass merit and market value...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726670/solid-state-nanopore-based-biomimetic-voltage-gated-ion-channels
#16
Matthew Pevarnik, Weibin Cui, Sukru Yemenicioglu, Justin Rofeh, Luke Theogarajan
Voltage gating is essential to the computational ability of neurons. We show this effect can be mimicked in a solid-state nanopore by functionalizing the pore interior with a redox active molecule. We study the integration of an active biological molecule, a quinone, into a solid state nanopore and its subsequent induced voltage gating. We show that the voltage gating effect mimics biological gating systems in its classic sigmoidal voltage response, unlike previous synthetic voltage gating systems. Initially the quinone undergoes a reduction due to radicals in the bulk solution and is converted to the hydroquinone state...
July 20, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28726541/characterization-of-postsynaptic-calcium-signals-in-the-pyramidal-neurons-of-anterior-cingulate-cortex
#17
Xu-Hui Li, Qian Song, Tao Chen, Min Zhuo
Calcium signaling is critical for synaptic transmission and plasticity. N-methyl-D-aspartic acid (NMDA) receptors play a key role in synaptic potentiation in the anterior cingulate cortex. Most previous studies of calcium signaling focus on hippocampal neurons, little is known about the activity-induced calcium signals in the anterior cingulate cortex. In the present study, we show that NMDA receptor-mediated postsynaptic calcium signals induced by different synaptic stimulation in anterior cingulate cortex pyramidal neurons...
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28724996/dynamics-of-high-viscosity-contrast-confluent-microfluidic-flows
#18
Michael E Kurdzinski, Berrak Gol, Aaron Co Hee, Peter Thurgood, Jiu Yang Zhu, Phred Petersen, Arnan Mitchell, Khashayar Khoshmanesh
The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large viscosity contrast between the neighbouring flows leading to unique instability patterns along their interface. Here, we study the dynamics of high viscosity contrast confluent flows - specifically a core flow made of highly viscous glycerol confined by sheath flows made of water within a microfluidic flow focusing system...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28723891/the-lysosomal-potassium-channel-tmem175-adopts-a-novel-tetrameric-architecture
#19
Changkeun Lee, Jiangtao Guo, Weizhong Zeng, Sunghoon Kim, Ji She, Chunlei Cang, Dejian Ren, Youxing Jiang
TMEM175 is a lysosomal K(+) channel that is important for maintaining the membrane potential and pH stability in lysosomes. It contains two homologous copies of a six-transmembrane-helix (6-TM) domain, which has no sequence homology to the canonical tetrameric K(+) channels and lacks the TVGYG selectivity filter motif found in these channels. The prokaryotic TMEM175 channel, which is present in a subset of bacteria and archaea, contains only a single 6-TM domain and functions as a tetramer. Here, we present the crystal structure of a prokaryotic TMEM175 channel from Chamaesiphon minutus, CmTMEM175, the architecture of which represents a completely different fold from that of canonical K(+) channels...
July 19, 2017: Nature
https://www.readbyqxmd.com/read/28723132/single-cell-mechanical-characteristics-analyzed-by-multiconstriction-microfluidic-channels
#20
Xiang Ren, Parham Ghassemi, Hesam Babahosseini, Jeannine S Strobl, Masoud Agah
A microfluidic device composed of variable numbers of multiconstriction channels is reported in this paper to differentiate a human breast cancer cell line, MDA-MB-231, and a nontumorigenic human breast cell line, MCF-10A. Differences between their mechanical properties were assessed by comparing the effect of single or multiple relaxations on their velocity profiles which is a novel measure of their deformation ability. Videos of the cells were recorded via a microscope using a smartphone, and imported to a tracking software to gain the position information on the cells...
February 24, 2017: ACS Sensors
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