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Xiaoling Wang

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https://www.readbyqxmd.com/read/28212646/linking-long-non-coding-rnas-and-swi-snf-complexes-to-chromatin-remodeling-in-cancer
#1
REVIEW
Yanyan Tang, Jinpeng Wang, Yu Lian, Chunmei Fan, Ping Zhang, Yingfen Wu, Xiayu Li, Fang Xiong, Xiaoling Li, Guiyuan Li, Wei Xiong, Zhaoyang Zeng
Chromatin remodeling controls gene expression and signaling pathway activation, and aberrant chromatin structure and gene dysregulation are primary characteristics of human cancer progression. Recent reports have shown that long non-coding RNAs (lncRNAs) are tightly associated with chromatin remodeling. In this review, we focused on important chromatin remodelers called the switching defective/sucrose nonfermenting (SWI/SNF) complexes, which use the energy of ATP hydrolysis to control gene transcription by altering chromatin structure...
February 17, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28209335/impact-of-fluid-status-and-inflammation-and-their-interaction-on-survival-a-study-in-an-international-hemodialysis-patient-cohort
#2
Marijke J E Dekker, Daniele Marcelli, Bernard J Canaud, Paola Carioni, Yuedong Wang, Aileen Grassmann, Constantijn J A M Konings, Peter Kotanko, Karel M Leunissen, Nathan W Levin, Frank M van der Sande, Xiaoling Ye, Vaibhav Maheshwari, Len A Usvyat, Jeroen P Kooman
In hemodialysis patients extracellular fluid overload is a predictor of all-cause and cardiovascular mortality, and a relation with inflammation has been reported in previous studies. The magnitude and nature of this interaction and the effects of moderate fluid overload and extracellular fluid depletion on survival are still unclear. We present the results of an international cohort study in 8883 hemodialysis patients from the European MONDO initiative database where, during a three-month baseline period, fluid status was assessed using bioimpedance and inflammation by C-reactive protein...
February 13, 2017: Kidney International
https://www.readbyqxmd.com/read/28203567/identification-of-three-novel-splicing-variants-and-expression-analysis-of-chicken-gpr1-gene
#3
Xueyou Zhang, Qihai Xiao, Kai Tian, Yan Wang, Xiaoling Zhao, Huadong Yin, Diyan Li, Qing Zhu
GPR1 is a G protein-coupled receptor that plays critical roles in eukaryotic cells: typically, response to glucose stimulation, lipid accumulation, and transmitting nutrition signals to cAMP pathway. However, the alternative splicing of the GPR1 gene and its expression pattern in chicken tissues and ovarian follicles were unknown. In our current study, we used RACE-PCR to identify three GPR1 variants, including the full-length variant (GPR1-va1) and two alternatively spliced variants (GPR1-va2, GPR1-vb). Quantitative real-time PCR examined the expression pattern of GPR1 mRNA in chicken tissues and ovarian follicles...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28199852/b-cell-activating-factor-baff-selects-il-10-b-cells-over-il-10-b-cells-during-inflammatory-responses
#4
Ning Ma, Yu Zhang, Qilin Liu, Zhiding Wang, Xiaoling Liu, Gaizhi Zhu, Dandan Yu, Gencheng Han, Guojiang Chen, Chunmei Hou, Tianxiao Wang, Yuanfang Ma, Beifen Shen, Yan Li, He Xiao, Renxi Wang
B cell activating factor (BAFF) regulates B cell maturation, survival, function, and plays a critical pathogenic role in autoimmune diseases. It remains unclear how BAFF affects IL-10(-)B cells versus regulatory B cells (Bregs) in inflammatory responses. In this study, we found that IL-10-expressing Bregs decreased in lupus-prone MRL/lpr mice and experimental allergic encephalomyelitis (EAE) mice. On blockade of the effects of BAFF with TACI-IgG, IL-10(+) Bregs were upregulated in MRL/lpr and EAE mice. In addition, BAFF expanded IL-10(+)B cells over IL-10(-)B cells under noninflammatory conditions in vitro, whereas it expanded IL-10(-)B cells over IL-10(+)B cells during inflammatory responses, such as stimulation with autoantigen and LPS...
February 12, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/28198372/novel-characteristics-of-the-avian-gyrovirus-2-genome
#5
Shuai Yao, Xiang Gao, Tianbei Tuo, Chunyan Han, Yulong Gao, Xiaole Qi, Yanping Zhang, Changjun Liu, Honglei Gao, Yongqiang Wang, Xiaomei Wang
Avian gyrovirus 2 (AGV2) was the second member of the viral genus Cyclovirus to be discovered. This virus poses a significant potential threat to humans and poultry due to its global dissemination and infectiousness. We used three overlapping polymerase chain reactions (PCRs) to map the whole genome of AGV2. We then modelled the evolutionary history of these novel sequence data in the context of related sequences from GenBank. We analysed the viral protein characteristics of the different phylogenetic groups and explored differences in evolutionary trends between Chinese strains and strains from other countries...
February 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28183598/immobilization-of-heparin-poly-l-lysine-microspheres-on-medical-grade-high-nitrogen-nickel-free-austenitic-stainless-steel-surface-to-improve-the-biocompatibility-and-suppress-thrombosis
#6
Menghua Li, Haide Wu, Yi Wang, Tieying Yin, Hans Gregersen, Xiaojuan Zhang, Xiaoling Liao, Guixue Wang
Thrombosis formation, restenosis, and delayed endothelium regeneration continue to be a challenge for coronary artery stent therapy. To improve the hemocompatibility of cardiovascular implants and to selectively direct vascular cell behavior, a novel heparin/poly-l-lysine microsphere was developed and immobilized on a dopamine-coated surface. We chose medical grade high nitrogen nickel-free austenitic stainless steel as the stent material since it has better biocompatibility. The stability and structural characteristics of the microspheres changed with the heparin: poly-l-lysine concentration ratio...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28180282/ataxin-3-promotes-genome-integrity-by-stabilizing-chk1
#7
Yingfeng Tu, Hongmei Liu, Xuefei Zhu, Hongyan Shen, Xiaolu Ma, Fengli Wang, Min Huang, Juanjuan Gong, Xiaoling Li, Yun Wang, Caixia Guo, Tie-Shan Tang
No abstract text is available yet for this article.
February 9, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28180068/early-cortical-biomarkers-of-longitudinal-transcutaneous-vagus-nerve-stimulation-treatment-success-in-depression
#8
Jiliang Fang, Natalia Egorova, Peijing Rong, Jun Liu, Yang Hong, Yangyang Fan, Xiaoling Wang, Honghong Wang, Yutian Yu, Yunyao Ma, Chunhua Xu, Shaoyuan Li, Jingjun Zhao, Man Luo, Bing Zhu, Jian Kong
Transcutaneous vagus nerve stimulation (tVNS), a non-invasive method of brain stimulation through the auricular branch of the vagus nerve, has shown promising results in treating major depressive disorder (MDD) in several pilot studies. However, the neural mechanism by which the effect on depression might be achieved has not been fully investigated, with only a few neuroimaging studies demonstrating tVNS-induced changes in the brains of healthy volunteers. Identifying specific neural pathways, which are influenced by tVNS compared with sham in depressed individuals, as well as determining neurobiomarkers of tVNS treatment success are needed to advance the application of tVNS for MDD...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28176286/aptamer-combined-with-fluorescent-silica-nanoparticles-for-detection-of-hepatoma-cells
#9
Zixi Hu, Juntao Tan, Zongqiang Lai, Rong Zheng, Jianhong Zhong, Yiwei Wang, Xiaoxue Li, Nuo Yang, Jieping Li, Wei Yang, Yong Huang, Yongxiang Zhao, Xiaoling Lu
PURPOSE: The purpose of this study is to develop a simple, effective method to label hepatoma cells with aptamers and then detect them using fluorescent silica nanoparticles (FSNPs). METHOD: Streptavidin was conjugated to carboxyl-modified fluorescein isothiocyanate (FITC)-doped silica nanoparticles which were prepared by the reverse microemulsion method. The resulting streptavidin-conjugated fluorescent silica nanoparticles (SA-FSNPs) were mixed with hepatoma cells that had been labeled with biotin-conjugated aptamer TLS11a (Bio-TLS11a)...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28171855/prognostic-value-of-the-delivery-dialysis-dose-on-twice-weekly-hemodialysis-patients
#10
Qichen Fan, Yucheng Yan, Leyi Gu, Liqun He, Nan Chen, Gengru Jiang, Li Yuan, Jun Xue, Yun Zhang, Jun Ma, Huimin Jin, Weijie Yuan, Zhiyong Guo, Lili Guo, Niansong Wang, Wei Zhang, Zhibin Ye, Peiju Mao, Xiaoling Pi, Renhua Lu, Mingli Zhu, Weiming Zhang, Zhaohui Ni, Jiaqi Qian, Huihua Pang
BACKGROUND: Few studies have evaluated the prognostic value of dialysis dose in twice-weekly hemodialysis (HD). A single-pool Kt/V (spKt/V) over 1.70 may benefit patients receiving twice-weekly maintenance HD. METHODS: This is a multicenter randomized controlled trial performed on 163 patients from 17 dialysis centers in Shanghai who were allocated to high- (n = 98) and standard-dose groups (n = 65) and followed through 96 weeks of study period. Therapeutic approaches were given to increase spKt/V to over 1...
February 8, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28168564/first-flush-characteristics-of-rainfall-runoff-from-a-paddy-field-in-the-taihu-lake-watershed-china
#11
Songmin Li, Xiaoling Wang, Bin Qiao, Jiansheng Li, Jiamin Tu
Nonpoint storm runoff remains a major threat to surface water quality in China. As a paddy matures, numerous fertilizers are needed, especially in the rainy seasons; the concentration of nitrogen and phosphorus in rainfall runoff from farmland is much higher than at other times, and this poses a great threat to water bodies and is the main reason for water eutrophication, especially in high concentration drainages. To date, most studies regarding the characteristics of pollutants in rainfall runoff have mainly been concentrated on urban runoff and watershed runoff; therefore, it is particularly important to investigate the characteristics of nitrogen and phosphorus loss in rainfall runoff from paddy fields...
February 6, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28165815/effective-improvement-of-the-neuroprotective-activity-after-spinal-cord-injury-by-synergistic-effect-of-glucocorticoid-with-biodegradable-amphipathic-nanomicelles
#12
YueLong Wang, Min Wu, Lei Gu, XiaoLing Li, Jun He, LiangXue Zhou, Aiping Tong, Juan Shi, HongYan Zhu, JianGuo Xu, Gang Guo
Dexamethasone acetate (DA) produces neuroprotective effects by inhibiting lipid peroxidation and inflammation by reducing cytokine release and expression. However, its clinical application is limited by its hydrophobicity, low biocompatibility and numerous side effects when using large dosage. Therefore, improving DA's water solubility, biocompatibility and reducing its side effects are important goals that will improve its clinical utility. The objective of this study is to use a biodegradable polymer as the delivery vehicle for DA to achieve the synergism between inhibiting lipid peroxidation and inflammation effects of the hydrophobic-loaded drugs and the amphipathic delivery vehicle...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28159582/a-comparative-evaluation-of-cbct-outcomes-of-two-closed-treatment-methods-in-intracapsular-condylar-fractures
#13
Yanmei Tang, Min Zhu, Xiaoling Wang, Yanfei Zhu, Huijun Sun
PURPOSE: The cone beam computed tomography (CBCT) images of 2 closed treatments are compared for intracapsular condylar fractures (ICFs) to learn whether splint treatment could promote better radiologic outcomes. PATIENTS AND METHODS: Fifty-four patients with 60 sides of ICF were divided into 2 groups. In the control group (C-group), patients had a liquid diet for 1 month. In the trial group (T-group), patients wore splints with anterior elastic traction. Local CBCT images of the temporomandibular joint were obtained at T0 (mean 8...
December 7, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28154554/the-denitrification-characteristics-and-microbial-community-in-the-cathode-of-an-mfc-with-aerobic-denitrification-at-high-temperatures
#14
Jianqiang Zhao, Jinna Wu, Xiaoling Li, Sha Wang, Bo Hu, Xiaoqian Ding
Microbial fuel cells (MFCs) have attracted much attention due to their ability to generate electricity while treating wastewater. The performance of a double-chamber MFC with simultaneous nitrification and denitrification (SND) in the cathode for treating synthetic high concentration ammonia wastewater was investigated at different dissolved oxygen (DO) concentrations and high temperatures. The results showed that electrode denitrification and traditional heterotrophic denitrification co-existed in the cathode chamber...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28144002/incomplete-kawasaki-disease-presenting-with-abdominal-pain-diagnosed-by-echocardiography
#15
Hao Yang, Hui Wang, Xiaoling Zhang, Li Rao
No abstract text is available yet for this article.
January 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28143578/circular-rnas-in-human-cancer
#16
REVIEW
Yumin Wang, Yongzhen Mo, Zhaojian Gong, Xiang Yang, Mo Yang, Shanshan Zhang, Fang Xiong, Bo Xiang, Ming Zhou, Qianjin Liao, Wenling Zhang, Xiayu Li, Xiaoling Li, Yong Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong
CircRNAs are a novel type of RNAs. With the newly developed technology of next-generation sequencing (NGS), especially RNA-seq technology, over 30,000 circRNAs have already been found. Owing to their unique structure, they are more stable than linear RNAs. CircRNAs play important roles in the carcinogenesis of cancer. The expression of circRNAs is correlated with patients' clinical characteristics, and circRNAs play a vital role in many aspects of malignant phenotypes, including cell cycle, apoptosis, vascularization, and invasion; metastasis as a RNA sponge, binding to RBP; or translation...
January 31, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28143420/papulonodular-mucinosis-guillain-barr%C3%A3-syndrome-and-nephrotic-syndrome-in-a-patient-with-systemic-lupus-erythematosus-a-case-report
#17
Xiaole Su, Xi Qiao, Jing Li, Lifang Gao, Chen Wang, Lihua Wang
BACKGROUND: Awareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients. CASE PRESENTATION: A 26-year-old Chinese man with SLE initially manifested cutaneous papulonodular mucinosis and developed acute Guillain-Barré syndrome and class V lupus nephritis 2 years later. His cutaneous nodules had not been idententified for 2 years and were resected by surgical procedures twice until SLE was diagnosed...
February 1, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28131624/involvement-of-pkc%C3%AE-and-erk1-2-signaling-pathways-in-egcg-s-protection-against-stress-induced-neural-injuries-in-wistar-rats
#18
Xiaoling Zhao, Fengqin Liu, Haimin Jin, Renjia Li, Yonghui Wang, Wanqi Zhang, Haichao Wang, Weiqiang Chen
Stress-induced neural injuries are closely linked to the pathogenesis of various neuropsychiatric disorders and psychosomatic diseases. We and others have previously demonstrated certain protective effects of epigallocatechin-3-gallate (EGCG) in stress-induced cerebral impairments, but the underlying protective mechanisms still remain poorly elucidated. Here we provide evidence to support the possible involvement of PKCα and extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathways in EGCG-mediated protection against restraint stress-induced neural injuries in rats...
January 25, 2017: Neuroscience
https://www.readbyqxmd.com/read/28125986/clinical-analysis-of-small-cell-carcinoma-of-the-bladder-in-chinese-nine-case-reports-and-literature-reviews
#19
Zhi Chen, Qingquan Liu, Ruibao Chen, Zhuo Liu, Mingchao Li, Qing Ling, Licheng Wu, Jun Yang, Xiaming Liu, Tao Wang, Zhiquan Hu, Xiaoling Guo, Shaogang Wang, Weiming Yang, Jihong Liu
BACKGROUND: Small cell carcinoma of the bladder (SCCB) is a kind of rare and highly aggressive tumor that is present in an advanced stage and has a propensity for early metastasis. The main presenting symptom of SCCB is hematuria. Surgery, chemotherapy, and radiotherapy, either alone or as a part of combined therapy, have been used as the treatment. The aim of this study is to present our experience with 9 SCCB patients who were treated with different modalities and to share the findings upon reviewing the literatures for patients with SCCB reported in 56 literatures in Chinese...
January 26, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28123602/high-expression-of-linc01420-indicates-an-unfavorable-prognosis-and-modulates-cell-migration-and-invasion-in-nasopharyngeal-carcinoma
#20
Liting Yang, Yanyan Tang, Yi He, Yumin Wang, Yu Lian, Fang Xiong, Lei Shi, Shanshan Zhang, Zhaojian Gong, Yujuan Zhou, Qianjin Liao, Ming Zhou, Xiaoling Li, Wei Xiong, Yong Li, Guiyuan Li, Zhaoyang Zeng, Can Guo
Recent studies demonstrated that long non-coding RNAs (lncRNAs) deregulated in many cancer tissues including nasopharyngeal carcinoma (NPC) and had critical roles in cancer progression and metastasis. In this study, we aimed to assess a lncRNA LINC01420 expression in NPC and explore its role in NPC pathogenesis. Our research revealed that the expression level of LINC01420 in NPC tissues were higher than nasopharyngeal epithelial (NPE) tissues. Moreover, NPC patients with high LINC01420 expression level showed poor overall survival...
2017: Journal of Cancer
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