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https://www.readbyqxmd.com/read/29788309/rethinking-the-outpatient-medication-list-increasing-patient-activation-and-education-while-architecting-for-centralization-and-improved-medication-reconciliation
#1
Frank Pandolfe, Adam Wright, Warner V Slack, Charles Safran
Objective: Identify barriers impacting the time consuming and error fraught process of medication reconciliation. Design and implement an electronic medication management system where patient and trusted healthcare proxies can participate in establishing and maintaining an inclusive and up-to-date list of medications. Methods: A patient-facing electronic medication manager was deployed within an existing research project focused on elder care management funded by the AHRQ, InfoSAGE, allowing patients and patients' proxies the ability to build and maintain an accurate and up-to-date medication list...
May 17, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29780008/retrospective-evaluation-of-anti-toxoplasma-gondii-antibody-among-first-trimester-pregnant-women-admitted-to-nenehatun-maternity-hospital-between-2013-2017-in-erzurum
#2
Esra Çınar Tanrıverdi, Berrin Göktuğ Kadıoğlu, Handan Alay, Zülal Özkurt
OBJECTIVE: We aimed to investigate the Toxoplasma gondii seropositivity in pregnant women who referred to Erzurum Nenehatun Hospital for antenatal care, and to compare our data with other regions of Turkey. METHODS: In this retrospective study we evaluated Anti-Toxoplasma gondii IgM and anti-Toxoplasma gondii IgG screening results of pregnant women who admitted to our hospital between January 2013 and December 2016 for antenatal care. The data was obtained from hospital's digital data system and patient folders...
May 21, 2018: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29771227/team-development-among-physician-leaders-at-the-cleveland-clinic
#3
Tracy H Porter, James K Stoller, Scott J Allen
Purpose Since 1990, the Cleveland Clinic has trained physicians in team skills through various iterations of a program called Leading in Healthcare (LHC). In the present study, the authors utilize a case study approach to gain insight into the LHC curriculum, and more specifically, the team project. The purpose of this paper is to better understand the Cleveland Clinic's position on the issue and its approach to education - specifically among physicians. Design/methodology/approach The authors utilized a case study approach with four key program architects...
May 8, 2018: Leadership in Health Services
https://www.readbyqxmd.com/read/29769276/analytical-comparison-of-the-architect-syphilis-tp-and-liaison-treponema-assay-automated-chemiluminescent-immunoassays-and-their-performance-in-a-reverse-syphilis-screening-algorithm
#4
Alan M Sanfilippo, Kristie Freeman, John L Schmitz
Syphilis incidence has increased in the United States since 2000 (1, 2) and remains a global public health concern (3, 4).….
May 16, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29763574/how-low-can-you-go-analytical-performance-of-five-automated-testosterone-immunoassays
#5
Sonia L La'ulu, Kimberly J Kalp, Joely A Straseski
BACKGROUND: Testosterone is commonly measured using immunoassays, yet concerns with the accuracy and quality of testing by these methods exist, particularly for low testosterone concentrations. Study objectives were to evaluate selective performance characteristics, including functional sensitivity (FS), of 5 automated immunoassays for total testosterone. METHODS: FS, imprecision, assay interference, limit of blank, linearity, and accuracy were assessed using the Abbott ARCHITECT i2000SR , SIEMENS ADVIA Centaur and IMMULITE 2000, Beckman Coulter DxI 800, and Roche MODULAR E170...
May 12, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29763401/altarum-s-mesa-turns-high-deductible-coverage-on-its-head
#6
Michael D Dalzell
The architects of Medical Episode Spending Allowance (MESA) benefits are radically reframing coverage as allowances for episodes of care and have a plan for engaging members in making better choices. MESA could catch on quickly, particularly with plan sponsors who have seen consumer-directed plan designs work against them.
May 2018: Managed Care
https://www.readbyqxmd.com/read/29756456/no-time-to-delay-fiebig-stages-and-referral-in-acute-hiv-infection-seattle-primary-infection-program-experience
#7
Joanne Stekler, Kenneth Tapia, Janine Maenza, Claire E Stevens, George Ure, Joshua O'Neal, Aric Lane, James I Mullins, Robert Coombs, Sarah E Holte, Ann Cornwall Collier
INTRODUCTION: There has been increasing recognition of the importance of diagnosing individuals during the earliest stages of HIV infection. MATERIALS AND METHODS: Sera from individuals referred to a primary HIV infection research program were screened using the IgG-sensitive Vironostika HIV-1 Microelisa System, IgG/IgM-sensitive GS HIV-1/HIV-2 Plus O antibody EIA, or Abbott ARCHITECT HIV Ag/Ab Combo assay and confirmed by the Bio-Rad Multispot and Western Blot...
May 14, 2018: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/29746252/establishing-normal-values-of-total-testosterone-in-adult-healthy-men-by-the-use-of-four-immunometric-methods-and-liquid-chromatography-mass-spectrometry
#8
Giacomo Montagna, Samuela Balestra, Federica D'Aurizio, Francesco Romanelli, Cinzia Benagli, Renato Tozzoli, Lorenz Risch, Luca Giovanella, Mauro Imperiali
BACKGROUND: The total testosterone (T) cutoffs clinically adopted to define late-onset hypogonadism (LOH) do not consider the differences that exist between different analytical platforms, nor do they consider the body mass index (BMI) or age of the patient. We aimed at providing method, age and BMI-specific normal values for total T in European healthy men. METHODS: A total of 351 eugonadal healthy men were recruited, and total T was measured with four automated immunometric assays (IMAs): ARCHITECT i1000SR (Abbott), UniCel DxI800 (Beckman Coulter), Cobas e601 (Roche), IMMULITE 2000 (Siemens) and liquid chromatography-tandem mass spectrometry (LC-MS/MS)...
May 10, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29743308/performance-evaluation-of-a-prototype-architect-antibody-assay-for-babesia-microti
#9
Kevin Cheng, Kelly E Coller, Christopher C Marohnic, Zachary A Pfeiffer, James R Fino, Randee R Elsing, Janet Bergsma, Marilee A Marcinkus, Alak K Kar, Orlando H Gumbs, Kathy S Otis, Jeffrey Fishpaugh, Phillip W Schultz, Mark R Pope, Alfredo R Narvaez, Susan J Wong, Susan Madison-Antenucci, Thomas P Leary, George J Dawson
The tick-borne protozoan Babesia microti is responsible for more than 200 cases of transfusion-transmitted babesiosis (TTB) infection in the United States over the last 30 years. Measures to mitigate the risk of TTB include nucleic acid testing (NAT) and B. microti antibody testing. A fully automated prototype B. microti antibody test was developed on the ARCHITECT instrument. The specificity was determined to be 99.98% in volunteer blood donors (n=28,740) from areas considered as low endemic for B. microti The sensitivity of the prototype test was studied in experimentally-infected macaques; a total of 128 samples were detected compared to 125 with the indirect fluorescent antibody test (IFA), additionally, 83 (89...
May 9, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29739096/measurement-differences-between-two-immunoassay-systems-for-lh-and-fsh-a-comparison-of-roche-cobas-e601-vs-abbott-architect-i2000sr
#10
Lianli Yin, Yinghua Tang, Xiang Chen, Yifan Sun
BACKGROUND: Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) regulate the growth and reproductive activity of gonadal tissue and determine the concentration of LH is essential for the prediction of ovulation. Collectively, FSH and LH are important measurements to ascertain the causes of infertility as well as diagnosing disorders such as polycystic ovary syndrome and pituitary and gonadal dysfunction. This study compares the correlation between LH and FSH measurements during examination with two different systems, Architect i2000sr (Abbott Laboratories; Lake Bluff, IL, USA) and Cobas e601 (Roche; Geneva, Switzerland), and assesses the differences between these systems...
March 1, 2018: Clinical Laboratory
https://www.readbyqxmd.com/read/29735211/envisioning-bodies-and-architectures-of-care-reflections-on-competition-designs-for-older-people
#11
Sarah Nettleton, Christina Buse, Daryl Martin
Architects shape future dwellings and built environments in ways that are critical for aging bodies. This article explores how assumptions about aging bodies are made manifest in architectural plans and designs. By analysing entries for an international student competition Caring for Older People (2009), we illustrate the ways in which aged bodies were conceived by future architectural professionals. Through analysing the architectural plans, we can discern the students' expectations and assumptions about aging bodies and embodiment through their use of and reference to spaces, places and things...
June 2018: Journal of Aging Studies
https://www.readbyqxmd.com/read/29719993/architecture-for-health-is-not-just-for-healthcare-architects
#12
Andrew L Dannenberg, Heather Burpee
No abstract text is available yet for this article.
January 1, 2018: HERD
https://www.readbyqxmd.com/read/29716287/pre-sabine-room-acoustic-design-guidelines-based-on-human-voice-directivity
#13
Barteld N J Postma, Sebastien Jouan, Brian F G Katz
With the work of Wallace C. Sabine on the lecture hall of the Fogg Art Museum and concert hall of Boston Symphony Hall, a foundation for the field of architectural acoustics as a science was laid between 1895 and 1900. Prior to that, architects employed various notions in acoustic design. Previous studies by the authors have reviewed 18th and 19th century design guidelines that were based on the quantification of the perception threshold between direct sound and first order reflections, with these guidelines being followed in the design of several rooms with acoustical demands...
April 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29706642/genes-flow-by-the-channels-of-culture-the-genetic-imprint-of-matrilocality-in-ngazidja-comoros-islands
#14
Stéphane Mazières, Pauline Oviedo, Célia Kamel, Pascal Bailly, Caroline Costedoat, Jacques Chiaroni
Post-marital residence of spouses is one of the architects of population genetic structure. In the present study, we tested how the place of residence of males and females in Ngazidja, Comoros Islands, has unequally channeled, by dispersal among villages, the male and female genetic diversity. Using sequences of the hypervariable segment I of the mitochondrial DNA (mtDNA HVS-I) and six Y-chromosome microsatellites (Y-STRs), we measured the genetic variation and male-to-female effective number of migrants ratios based on FST values and revealed a genetic structure mostly driven by male gene flow across villages...
April 30, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29704735/heterophilic-interference-in-specimens-yielding-false-reactive-results-on-the-abbott-4th-generation-architect-hiv-ag-ab-combo-assay
#15
S Lavoie, D Caswell, M J Gill, K Kadkhoda, C L Charlton, P N Levett, T Hatchette, R Garceau, J Maregmen, T Mazzulli, R Needle, K Kadivar, J Kim
BACKGROUND: False-reactivity in HIV-negative specimens has been detected in HIV fourth-generation antigen/antibody or 'combo' assays which are able to detect both anti-HIV-1/HIV-2 antibodies and HIV-1 antigen. OBJECTIVES: We sought to characterize these specimens and determine the effect of heterophilic interference. STUDY DESIGN: Specimens previously testing as false-reactive on the Abbott ARCHITECT HIV Ag/Ab combo assay and re-tested on a different (Siemens ADVIA Centaur HIV Ag/Ab) assay...
April 12, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29701836/diagnostic-value-of-serum-concentration-and-integrity-of-circulating-cell-free-dna-in-breast-cancer-a-comparative-study-with-cea-and-ca15-3
#16
Zijie Tang, Li Li, Lei Shen, Xianjuan Shen, Shaoqing Ju, Hui Cong
Breast cancer (BC) is one of the most common types of malignant neoplasm in women; the incidence of BC increases yearly. In a previous study, a novel and sensitive method for quantitying cell-free DNA (CFD) in human blood was established and tested for its ability to predict which patients harbored tumors. Our objective in this study was to investigate the clinical value of serum concentration and the integrity of circulating free DNA (CFD) as a biomarker for auxiliary diagnosis of BC. The concentration of CFD was quantitated by branched DNA (bDNA)-based Alu assay...
April 26, 2018: Laboratory Medicine
https://www.readbyqxmd.com/read/29701125/technical-and-clinical-performance-of-a-new-assay-to-detect-squamous-cell-carcinoma-antigen-levels-for-the-differential-diagnosis-of-cervical-lung-and-head-and-neck-cancer
#17
MULTICENTER STUDY
Stefan Holdenrieder, Rafael Molina, Ling Qiu, Xiuyi Zhi, Sandra Rutz, Christine Engel, Pia Kasper-Sauer, Farshid Dayyani, Catharina M Korse
In squamous cell carcinoma, squamous cell carcinoma antigen levels are often elevated. This multi-center study evaluated the technical performance of a new Elecsys® squamous cell carcinoma assay, which measures serum squamous cell carcinoma antigen 1 and 2 levels in an equimolar manner, and investigated the potential of squamous cell carcinoma antigen for differential diagnosis of cervical, lung, and head and neck squamous cell carcinoma.Assay precision and method comparison experiments were performed across three European sites...
April 2018: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/29700318/iron-deficiency-is-associated-with-hypothyroxinemia-and-hypotriiodothyroninemia-in-the-spanish-general-adult-population-di-bet-es-study
#18
Cristina Maldonado-Araque, Sergio Valdés, Ana Lago-Sampedro, Juan Antonio Lillo-Muñoz, Eduardo Garcia-Fuentes, Vidal Perez-Valero, Carolina Gutierrez-Repiso, Albert Goday, Ines Urrutia, Laura Peláez, Alfonso Calle-Pascual, Luis Castaño, Contxa Castell, Elias Delgado, Edelmiro Menendez, Josep Franch-Nadal, Sonia Gaztambide, Joan Girbés, Emilio Ortega, Joan Vendrell, Matilde R Chacón, Felipe J Chaves, Federico Soriguer, Gemma Rojo-Martínez
Previous studies have suggested that iron deficiency (ID) may impair thyroid hormone metabolism, however replication in wide samples of the general adult population has not been performed. We studied 3846 individuals free of thyroid disease, participants in a national, cross sectional, population based study representative of the Spanish adult population. Thyroid stimulating hormone (TSH), free thyroxin (FT4) and free triiodothyronine (FT3) were analyzed by electrochemiluminescence (E170, Roche Diagnostics)...
April 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29691270/combining-high-sensitivity-cardiac-troponin-i-and-cardiac-troponin-t-in-the-early-diagnosis-of-acute-myocardial-infarction
#19
Noreen van der Linden, Karin Wildi, Raphael Twerenbold, John W Pickering, Martin Than, Louise Cullen, Jaimi Greenslade, William Parsonage, Thomas Nestelberger, Jasper Boeddinghaus, Patrick Badertscher, Maria Rubini Giménez, Lieke J J Klinkenberg, Otto Bekers, Aline Schöni, Dagmar I Keller, Zaid Sabti, Christian Puelacher, Janosch Cupa, Lukas Schumacher, Nikola Kozhuharov, Karin Grimm, Samyut Shrestha, Dayana Flores, Michael Freese, Claudia Stelzig, Ivo Strebel, Òscar Miró, Katharina Rentsch, Beata Morawiec, Damian Kawecki, Wanda Kloos, Jens Lohrmann, A Mark Richards, Richard Troughton, Christopher Pemberton, Stefan Osswald, Marja P van Dieijen-Visser, Alma M Mingels, Tobias Reichlin, Steven J R Meex, Christian Mueller
Background -Combining two signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction (AMI) with a single blood draw. We aimed to evaluate the diagnostic performance of combinations of high sensitivity (hs) cTnI and hs-cTnT for the early diagnosis of AMI. Methods -The diagnostic performance of combining hs-cTnI (Architect, Abbott) and hs-cTnT (Elecsys, Roche) concentrations (sum, product, ratio and a combination algorithm) obtained at the time of presentation was evaluated in a large multicenter diagnostic study of patients with suspected AMI...
April 24, 2018: Circulation
https://www.readbyqxmd.com/read/29690509/design-of-urban-public-spaces-intent-vs-reality
#20
Mikkel Hjort, W Mike Martin, Tom Stewart, Jens Troelsen
This study investigated how two public spaces for sport and recreation were utilized by different user groups, and how this aligned with the initial design objectives for these spaces. Two newly built urban spaces situated in Copenhagen, Denmark, provided the context for this investigation. The System for Observing Play and Recreation in Communities (SOPARC) was used to examine the physical activity of users in these two urban spaces. The architects responsible for designing each space were interviewed to ascertain the intended target group of each space and to unravel the reasons behind the design decisions...
April 21, 2018: International Journal of Environmental Research and Public Health
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