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https://www.readbyqxmd.com/read/28816673/generating-arm-swing-trajectories-in-real-time-using-a-data-driven-model-for-gait-rehabilitation-with-self-selected-speed
#1
Babak Hejrati, Andrew S Merryweather, Jake J Abbott
Gait rehabilitation is often focused on the legs, and overlooks the role of the upper limbs. However, a variety of studies have demonstrated the importance of proper arm swing both during healthy walking and during rehabilitation. In this paper, we describe a method for generating proper arm-swing trajectories in real-time using only measurements of the angular velocity of a person's thighs, to be used during gait rehabilitation with self-selected walking speed. A datadriven linear time-invariant transfer function is developed, using frequency-response methods, which captures the frequencydependent magnitude and phase relationship between the thighs' angular velocities and the arm angles (measured at the shoulder, in the sagittal plane), using a data set of 30 healthy adult subjects...
August 14, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28815944/neonatal-fractures-as-a-presenting-feature-of-lmod3-associated-congenital-myopathy
#2
Megan Abbott, Mahim Jain, Rachel Pferdehirt, Yuqing Chen, Alyssa Tran, Mehmet B Duz, Mehmet Seven, Richard A Gibbs, Donna Muzny, Brendan Lee, Ronit Marom, Lindsay C Burrage
Nemaline myopathy is a rare inherited disorder characterized by weakness, hypotonia, and depressed deep tendon reflexes. It is clinically and genetically heterogeneous, with the most severe phenotype presenting as perinatal akinesia, severe muscle weakness, feeding difficulties and respiratory failure, leading to early mortality. Pathogenic variants in 12 genes, encoding components of the sarcomere or factors related to myogenesis, have been reported in patients affected with the disorder. Here, we describe an early, lethal presentation of decreased fetal movements, hypotonia, muscle weakness, and neonatal respiratory failure requiring ventilator support in three siblings from a consanguineous family...
August 16, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28813254/adapting-to-the-changing-needs-of-adolescents-parenting-practices-and-challenges-to-sensitive-attunement
#3
REVIEW
Roger Kobak, Caroline Abbott, Abigail Zisk, Nadia Bounoua
Changes in adolescents' motivations and capabilities pose unique challenges to parents who play a continuing role in ensuring the youth's safety and well-being. We describe sensitively attuned parenting as an optimal response to this challenge and summarize practices of positive engagement, supervision/guidance and open communication that support sensitive attunement and facilitate the continuing development of the adolescent's self-confidence, autonomous decision-making, and communication skills. We then consider factors that require parents to adapt their practices to the particular needs and developmental level of the adolescent...
June 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28812666/unknown-risks-to-soil-biodiversity-from-commercial-fungal-inoculants
#4
Miranda M Hart, Pedro M Antunes, Lynette K Abbott
No abstract text is available yet for this article.
March 23, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28811238/i-index-is-not-an-accurate-indicator-of-icteria-in-conjugated-hyperbilirubinemia
#5
Nora Nikolac Gabaj, Marijana Miler, Roman Mihic
INTRODUCTION: Serum indices have become a standard in assessing degree of endogenous interferences in serum and plasma samples. The aim of this study was to evaluate accuracy of I index in comparison with total bilirubin concentration in icteric samples with ranging amount of conjugated bilirubin. MATERIALS AND METHODS: This study retrospectively analyzed data from laboratory information system. Total, conjugated bilirubin and I index are measured on Abbott Architect c8000 (N=900)...
August 12, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28809400/prenatal-one-carbon-metabolism-dysregulation-programs-schizophrenia-like-deficits
#6
A Alachkar, L Wang, R Yoshimura, A R Hamzeh, Z Wang, N Sanathara, S M Lee, X Xu, G W Abbott, O Civelli
The methionine-folate cycle-dependent one-carbon metabolism is implicated in the pathophysiology of schizophrenia. Since schizophrenia is a developmental disorder, we examined the effects that perturbation of the one-carbon metabolism during gestation has on mice progeny. Pregnant mice were administered methionine equivalent to double their daily intake during the last week of gestation. Their progeny (MET mice) exhibited schizophrenia-like social deficits, cognitive impairments and elevated stereotypy, decreased neurogenesis and synaptic plasticity, and abnormally reduced local excitatory synaptic connections in CA1 neurons...
August 15, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28808561/quantifying-the-degree-of-bias-from-using-county-scale-data-in-species-distribution-modeling-can-increasing-sample-size-or-using-county-averaged-environmental-data-reduce-distributional-overprediction
#7
Steven D Collins, John C Abbott, Nancy E McIntyre
Citizen-science databases have been used to develop species distribution models (SDMs), although many taxa may be only georeferenced to county. It is tacitly assumed that SDMs built from county-scale data should be less precise than those built with more accurate localities, but the extent of the bias is currently unknown. Our aims in this study were to illustrate the effects of using county-scale data on the spatial extent and accuracy of SDMs relative to true locality data and to compare potential compensatory methods (including increased sample size and using overall county environmental averages rather than point locality environmental data)...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28808468/treatment-of-a-maxillary-second-molar-with-one-buccal-and-two-palatal-roots-confirmed-with-cone-beam-computed-tomography
#8
Masoud Parirokh, Mahsa Razifar, Hamed Manochehrifar, Paul V Abbott, Nima Hatami, Nargessaddat Kashi, Aida Farhadi
Root canal configuration is an important subject in endodontic practice and dentists should be familiar with all possible types of root canal configuration. A forty-three year old male was referred for root canal treatment of his maxillary left second molar tooth with symptomatic irreversible pulpitis. Pre-operative radiographs showed a three rooted molar. However, after access cavity preparation two palatal and one buccal orifices were detected. The patient was informed of the unusual root canal anatomy and cone-beam computed tomography (CBCT) was ordered for precise evaluation of the anatomy...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28805960/factors-associated-with-high-pain-intensity-during-wound-care-procedures-a-model
#9
Sue E Gardner, Linda I Abbott, Catherine A Fiala, Barbara A Rakel
The most common wound care procedures (WPCs) performed on open wounds are dressing changes and wound cleansing. Dressing changes cause moderate to severe pain in 74% of patients, nearly half (36%) of whom experience severe pain (rated as 8-10 on a 10-point numeric rating scale). The purpose of this paper is to propose a model of clinically accessible factors that can be tested in order to develop a clinical tool to identify which patients are likely to experience high intensity pain during nonoperative WCPs, such as dressing changes...
June 8, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28799987/a-brief-history-of-limb-lengthening
#10
John G Birch
In the last 35 years, orthopaedic surgeons have witnessed 3 major advances in the technique of limb lengthening: "distraction osteogenesis" facilitated by Gavriil Ilizarov method and infinitely-adaptable circular fixator with fine-wire bone fragment fixation; the introduction of the "6-strut" computer program-assisted circular fixators to effect complex deformity correction simultaneously; and the development of motorized intramedullary lengthening nails. However, the principles and associated complications of these techniques are on the basis of observations by Codivilla, Putti, and Abbott from as much as 110 years ago...
September 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28798784/comparison-of-closed-cell-and-hybrid-cell-stent-designs-in-carotid-artery-stenting-clinical-and-procedural-outcomes
#11
Ersan Tatli, Alptug Tokatli, Mehmet Bulent Vatan, Mustafa Tarik Agac, Huseyin Gunduz, Ramazan Akdemir, Harun Kilic
INTRODUCTION: Carotid artery stenting (CAS) is a promising alternative to surgery in high-risk patients. However, the impact of stent cell design on outcomes in CAS is a matter of continued debate. AIM: To compare the periprocedural and clinical outcomes of different stent designs for CAS with distal protection devices. MATERIAL AND METHODS: All CAS procedures with both closed- and hybrid-cell stents performed at our institution between February 2010 and December 2015 were analyzed retrospectively...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/28796202/the-complete-connectome-of-a-learning-and-memory-centre-in-an-insect-brain
#12
Katharina Eichler, Feng Li, Ashok Litwin-Kumar, Youngser Park, Ingrid Andrade, Casey M Schneider-Mizell, Timo Saumweber, Annina Huser, Claire Eschbach, Bertram Gerber, Richard D Fetter, James W Truman, Carey E Priebe, L F Abbott, Andreas S Thum, Marta Zlatic, Albert Cardona
Associating stimuli with positive or negative reinforcement is essential for survival, but a complete wiring diagram of a higher-order circuit supporting associative memory has not been previously available. Here we reconstruct one such circuit at synaptic resolution, the Drosophila larval mushroom body. We find that most Kenyon cells integrate random combinations of inputs but that a subset receives stereotyped inputs from single projection neurons. This organization maximizes performance of a model output neuron on a stimulus discrimination task...
August 9, 2017: Nature
https://www.readbyqxmd.com/read/28793216/smit1-modifies-kcnq-channel-function-and-pharmacology-by-physical-interaction-with-the-pore
#13
Rían W Manville, Daniel L Neverisky, Geoffrey W Abbott
Voltage-gated potassium channels of the KCNQ (Kv7) subfamily are essential for control of cellular excitability and repolarization in a wide range of cell types. Recently, we and others found that some KCNQ channels functionally and physically interact with sodium-dependent solute transporters, including myo-inositol transporters SMIT1 and SMIT2, potentially facilitating various modes of channel-transporter signal integration. In contrast to indirect effects such as channel regulation by SMIT-transported, myo-inositol-derived phosphatidylinositol 4,5-bisphosphate (PIP2), the mechanisms and functional consequences of the physical interaction of channels with transporters have been little studied...
August 8, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28793062/reflections-on-the-report-of-the-un-secretary-general-s-high-level-panel-on-access-to-medicines
#14
Frederick M Abbott
No abstract text is available yet for this article.
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28792038/quantifying-non-specific-interactions-between-flavour-and-food-biomolecules
#15
REVIEW
Seishi Shimizu, Steven Abbott, Nobuyuki Matubayasi
The ways in which flavour molecules interact with proteins in foods have an impact on flavour and aroma and on the (in)stability of the proteins. There is a long history of analysing these interactions using a "specific binding model" that gives values for the number of molecules, n, bound to the proteins with a binding constant Kb. However, recent progress in molecular thermodynamics forced us to reconsider this approach. In addition, there are a number of methods for determining these values and it is not at all clear whether the various assumptions behind the various methods allow legitimate comparisons between techniques...
August 9, 2017: Food & Function
https://www.readbyqxmd.com/read/28790166/noninferiority-trials-in-interventional-cardiology
#16
Dhaval Kolte, Herbert D Aronow, J Dawn Abbott
No abstract text is available yet for this article.
August 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28783842/building-better-policies
#17
Joey Berlin
Balances left on medical bills and unwarranted changes to medication: Those are just two of the ways in which health insurers can and do make life difficult for patients and physicians throughout Texas. Two bills that TMA backed in the 85th Texas legislative session - and that earned Gov. Greg Abbott's signature - won't eradicate those problems in Texas. But they should create some relief from the headaches that those two issues have caused throughout the years.
August 1, 2017: Texas Medicine
https://www.readbyqxmd.com/read/28783841/clearer-and-simpler
#18
Joey Berlin
Over the past several years, static has clouded the screen displaying telemedicine's proper role in health care as musings, arguments, and litigation created a need for real clarity. Now that TMA and other stakeholders put their collective heads together, the picture should clear up significantly. On May 27, Gov. Greg Abbott signed Senate Bill 1107, which allows telemedicine practitioners in Texas to know their requirements when they serve patients via telephone or other audiovisual means.
August 1, 2017: Texas Medicine
https://www.readbyqxmd.com/read/28783021/acoustic-environments-matter-synergistic-benefits-to-humans-and-ecological-communities
#19
REVIEW
Clinton D Francis, Peter Newman, B Derrick Taff, Crow White, Christopher A Monz, Mitchell Levenhagen, Alissa R Petrelli, Lauren C Abbott, Jennifer Newton, Shan Burson, Caren B Cooper, Kurt M Fristrup, Christopher J W McClure, Daniel Mennitt, Michael Giamellaro, Jesse R Barber
Protected areas are critical locations worldwide for biodiversity preservation and offer important opportunities for increasingly urbanized humans to experience nature. However, biodiversity preservation and visitor access are often at odds and creative solutions are needed to safeguard protected area natural resources in the face of high visitor use. Managing human impacts to natural soundscapes could serve as a powerful tool for resolving these conflicting objectives. Here, we review emerging research that demonstrates that the acoustic environment is critical to wildlife and that sounds shape the quality of nature-based experiences for humans...
August 3, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28781248/long-term-data-of-brs-presented-at-europcr-2017-friday-19-may
#20
Patrick W Serruys, Athanasios Katsikis, Yoshinobu Onuma
Bioresorbable scaffolds (BRS) were designed more than 30 years ago to overcome the disadvantages related to the permanent implantation of a metallic stent and, at present, a number of these devices have obtained a CE mark on the basis of midterm follow-up studies. However, although BRS have already been introduced into clinical practice, intensive research is ongoing worldwide to clarify their long-term safety and effectiveness. This type of research has captivated the interest of the cardiovascular community after the recent publication of long-term follow-up data from randomised trials demonstrating increased late scaffold thrombosis in the Absorb™ BRS (Abbott Vascular, Santa Clara, CA, USA)...
August 4, 2017: EuroIntervention
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