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https://www.readbyqxmd.com/read/29342093/hydroxyl-ion-diffusion-through-radicular-dentine-when-calcium-hydroxide-is-used-under-different-conditions
#1
Michael Cai, Paul Abbott, Jacqueline Castro Salgado
Calcium hydroxide's anti-bacterial action relies on high pH. The aim here was to investigate hydroxyl ion diffusion through dentine under different conditions. Teeth were divided into control (n = 4) and four experimental groups (n = 10): Group 1-no medicament; Group 2-Calmix; Group 3-Calmix/Ledermix; Group 4-Calasept Plus/Ledermix; Group 5-Pulpdent/smear layer. Deep (inner dentine) and shallow (outer dentine) cavities were cut into each root. pH was measured in these cavities for 12 weeks. The inner and outer dentine pH in Group 2 was significantly higher than all groups...
January 17, 2018: Materials
https://www.readbyqxmd.com/read/29339078/analytical-and-pre-analytical-performance-characteristics-of-a-novel-cartridge-type-blood-gas-analyzer-for-point-of-care-and-laboratory-testing
#2
Matthijs Oyaert, Tom Van Maerken, Silke Bridts, Silvi Van Loon, Heleen Laverge, Veronique Stove
BACKGROUND: Point-of-care blood gas test results may benefit therapeutic decision making by their immediate impact on patient care. We evaluated the (pre-)analytical performance of a novel cartridge-type blood gas analyzer, the GEM Premier 5000 (Werfen), for the determination of pH, partial carbon dioxide pressure (pCO2), partial oxygen pressure (pO2), sodium (Na+), potassium (K+), chloride (Cl-), ionized calcium (iCa2+), glucose, lactate, and total hemoglobin (tHb). METHODS: Total imprecision was estimated according to the CLSI EP5-A2 protocol...
January 12, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29338591/association-between-health-status-and-sociodemographic-clinical-and-treatment-disparities-in-the-patient-centered-outcomes-related-to-treatment-practices-in-peripheral-arterial-disease-investigating-trajectories-portrait-registry
#3
Adam M Noyes, J Dawn Abbott, Kensey Gosch, Kim Smolderen, John A Spertus, Omar Hyder, Peter Soukas, Mehdi H Shishehbor, Herbert D Aronow
Patients with peripheral artery disease (PAD) and intermittent claudication (IC) have impaired functional status and quality of life. However, little is known about which factors are associated with poorer health status at the time of initial presentation for PAD specialty care. Characterization of such features might provide insight into disparities that impact health status in this population. A total of 1258 patients from the United States, the Netherlands and Australia with new or worsened IC were enrolled at their first PAD specialty care visit between June 2011 and December 2015...
January 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29337020/inverse-association-between-plasma-homocysteine-concentrations-and-type-2-diabetes-mellitus-among-a-middle-aged-and-elderly-chinese-population
#4
C Yu, J Wang, F Wang, X Han, H Hu, J Yuan, X Miao, P Yao, S Wei, Y Wang, Y Liang, W Chen, X Zhang, H Guo, H Yang, Y Tang, D Zheng, T Wu, M He
BACKGROUND AND AIMS: Plasma homocysteine concentrations have been reported to be associated with type 2 diabetes mellitus (T2DM) with controversial findings. The aim of the present study was to investigate the association between plasma homocysteine concentrations and T2DM. METHODS AND RESULTS: A cross-sectional study including 19,085 eligible participants derived from the Dongfeng-Tongji cohort was conducted. Plasma homocysteine concentrations were measured by Abbott Architect i2000 Automatic analyzer and T2DM was defined according to American Diabetes Association criteria...
December 7, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29336208/the-effects-of-sex-differences-and-hormonal-contraception-on-outcomes-following-collegiate-sports-related-concussion
#5
Virginia Terwilliger Gallagher, Natalie Kramer, Kristin Abbott, John Alexander, Hans Breiter, Amy Herrold, Tory Lindley, Jeffrey Mjaanes, James Reilly
There is conflicting evidence regarding whether females are more adversely affected following concussion relative to males. Further, recent research suggests hormonal contraceptive (HC) use may affect symptom severity and duration post-concussion. The objective of this study was to examine the effects of sex and HC use on outcomes following concussion among collegiate varsity athletes. We hypothesized females would have longer length of recovery (LOR) and peak symptom severity would be associated with longer length of recovery in both males and females...
January 16, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29336014/response-to-yazdani-a-surgery-or-in-vitro-fertilisation-the-simplicity-of-this-question-belies-its-complexity-when-all-you-have-is-a-hammer-everything-looks-like-a-nail
#6
Jason Abbott
This is perhaps the most apt mantra of IVF (in vitro fertilisation) as a treatment in Australasia in this day and age. It is also important to note the truth in the identification of IVF being low skill-based, largely independent of the practitioner, but more importantly costly, and with few exceptions, only available in the private sector. Such revelations really require a rethink of the entire reproductive endocrinology and infertility (CREI) subspecialty. In fact, if there is only one solution to all fertility problems - that of the 'effective IVF procedure' - why not do away completely with the clinician and simply have nurse practitioners who oversee the identified issue of an individual or couple wanting a pregnancy? This in conjunction with the outstanding scientific advances that led to the initiation and promulgation of IVF really would reduce costs by cutting out the unnecessary clinician middle-person who is unimportant in the equation...
January 16, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29334648/using-mass-struvite-precipitation-to-remove-recalcitrant-nutrients-and-micropollutants-from-anaerobic-digestion-dewatering-centrate
#7
M Abel-Denee, T Abbott, C Eskicioglu
The primary objective of this research was to remove recalcitrant nutrients from anaerobically digested sludge dewatering centrate. A struvite precipitation methodology is proposed where salt crystals are encouraged to ballast colloidal particles through heterogeneous nucleation and subsequent crystal growth. The secondary objective was to assess presence of micropollutants in precipitates. Four biologically unique dewatering centrates were used to test the precipitation methodology on the variety of anaerobic digester configurations that can be expected from municipal wastewater treatment plant...
January 5, 2018: Water Research
https://www.readbyqxmd.com/read/29334132/oxybutynin-3-gel-for-the-treatment-of-primary-focal-hyperhidrosis-in-adolescents-and-young-adults
#8
Nicholas V Nguyen, Jane Gralla, James Abbott, Anna L Bruckner
BACKGROUND/OBJECTIVES: There are no reliably effective, well-tolerated topical agents for the treatment of hyperhidrosis. We sought to evaluate the efficacy and tolerability of oxybutynin 3% gel in adolescents and young adults with primary focal hyperhidrosis. METHODS: Patients with severe axillary hyperhidrosis were treated with topical oxybutynin 3% gel for 4 weeks. Response to treatment was assessed by calculating change in Hyperhidrosis Disease Severity Score from baseline to weeks 1 and 4...
January 15, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29333531/patient-reported-outcome-measures-prom-as-a-preoperative-assessment-tool
#9
Sunghye Kim, Pamela W Duncan, Leanne Groban, Hannah Segal, Rica Moonyeen Abbott, Jeff D Williamson
Aim of review: Patient-reported outcomes (PRO) on functional, social, and behavioral factors might be important preoperative predictors of postoperative outcomes. We conducted a literature review to explore associations of preoperative depression, socioeconomic status, social support, functional status/frailty, cognitive status, self-management skills, health literacy, and nutritional status with surgical outcomes. Methods: Two electronic data bases, including PubMed and Google Scholar, were searched linking either depression, socioeconomic status, social support, functional status/frailty, cognitive status, self-management skills, health literacy, or nutritional status with surgery, postoperative complications, or perioperative period within the past 2 decades...
November 28, 2017: Journal of anesthesia and perioperative medicine
https://www.readbyqxmd.com/read/29331740/development-and-validation-of-a-new-population-based-simulation-model-of-osteoarthritis-in-new-zealand
#10
Ross Wilson, J Haxby Abbott
OBJECTIVE: To describe the construction and preliminary validation of a new population-based microsimulation model developed to analyse the health and economic burden and cost-effectiveness of treatments for knee osteoarthritis (OA) in New Zealand (NZ). METHOD: We developed the New Zealand Management of Osteoarthritis (NZ-MOA) model, a discrete-time state-transition microsimulation model of the natural history of radiographic knee OA. In this article, we report on the model structure, derivation of input data, validation of baseline model parameters against external data sources, and validation of model outputs by comparison of the predicted population health loss with previous estimates...
January 10, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29327498/relationship-style-and-glycaemic-control-in-women-with-type-2-diabetes-the-mediating-role-of-psychological-distress
#11
Omar Braizat, Richard Feinn, Gina Abbott, Julie Wagner
This study examined whether depressive symptoms and/or diabetes distress mediate the association between relationship style and glycaemic control in women with diabetes. Seventy-five women with type 2 diabetes completed the Relationship Questionnaire. Participants endorsing "secure" or "preoccupied" adult attachment were combined into the interactive relationship style and "dismissing/avoidant" or "fearful" adult attachment were combined into the independent relationship style. Glycaemic control was a latent variable composed of A1c and 48-hr continuously measured glucose...
January 12, 2018: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/29326417/factors-causing-disagreement-between-measured-and-calculated-low-density-lipoprotein-cholesterol-ldl-c-in-clinical-laboratory-services
#12
Veeravan Lekskulchai
BACKGROUND Since measured low density lipoprotein-cholesterol (LDL-C) has been available in clinical laboratories, there have been concern about the disagreement between measured and calculated LDL-C and the factors causing their disagreement. MATERIAL AND METHODS Serum lipid concentrations were collected from 1,339 medical records of patients admitted to hospital between 2013 and 2015. They were grouped by their total cholesterol (TC), triglycerides (TG), and high-density lipoprotein-cholesterol (HDL-C) concentrations and the agreement between measured and calculated LDL-C was statistically analyzed...
January 12, 2018: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/29322517/discordant-human-t-lymphotropic-virus-screening-with-western-blot-confirmation-evaluation-of-the-dual-test-algorithm-for-us-blood-donations
#13
Susan L Stramer, Rebecca L Townsend, Gregory A Foster, Ramona Johnson, Barbara Weixlmann, Roger Y Dodd
BACKGROUND: Human T-lymphotropic virus (HTLV) blood donation screening has used a dual-testing algorithm beginning with either a chemiluminescent immunoassay or enzyme-linked immunosorbent screening assay (ELISA). Before the availability of a licensed HTLV supplemental assay, repeat-reactive (RR) samples on a first assay (Assay 1) were retested with a second screening assay (Assay 2). Donors with RR results by Assay 2 were deferred from blood donation and further tested using an unlicensed supplemental test to confirm reactivity while nonreactive (NR) donors remained eligible for donation until RR on a subsequent donation...
January 10, 2018: Transfusion
https://www.readbyqxmd.com/read/29319898/what-is-your-diagnosis-eyelid-mass-in-a-dog
#14
Laura J Black, Bianca da Costa Martins, Caryn E Plummer, Jeffrey R Abbott, Mary K Leissinger
No abstract text is available yet for this article.
January 10, 2018: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/29319627/opioid-prescription-morbidity-and-mortality-in-us-transplant-recipients
#15
Kevin C Abbott, Chyng-Wen Fwu, Paul W Eggers, Anne W Eggers, Prudence P Kline, Paul L Kimmel
BACKGROUND: CDC guidelines recommend caution in prescribing opioids for chronic pain. The characteristics of opioid prescription (OpRx) among kidney transplant (KTx) recipients has not been described in a national population. METHODS: We assessed OpRx prevalence among prevalent KTx recipients, and associated duration (chronic, defined as ≥90 days in a year) and dosing (in morphine milligram equivalents per day, MME, of <50, 50-89, and ≥90) with outcomes, death and graft loss, among incident KTx recipients using 2006-2010 US Renal Data System files, including Medicare Part D for medication ascertainment...
January 10, 2018: Transplantation
https://www.readbyqxmd.com/read/29317701/a-genome-wide-association-study-identifies-only-two-ancestry-specific-variants-associated-with-spontaneous-preterm-birth
#16
Nadav Rappoport, Jonathan Toung, Dexter Hadley, Ronald J Wong, Kazumichi Fujioka, Jason Reuter, Charles W Abbott, Sam Oh, Donglei Hu, Celeste Eng, Scott Huntsman, Dale L Bodian, John E Niederhuber, Xiumei Hong, Ge Zhang, Weronika Sikora-Wohfeld, Christopher R Gignoux, Hui Wang, John Oehlert, Laura L Jelliffe-Pawlowski, Jeffrey B Gould, Gary L Darmstadt, Xiaobin Wang, Carlos D Bustamante, Michael P Snyder, Elad Ziv, Nikolaos A Patsopoulos, Louis J Muglia, Esteban Burchard, Gary M Shaw, Hugh M O'Brodovich, David K Stevenson, Atul J Butte, Marina Sirota
Preterm birth (PTB), or the delivery prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. Although twin studies estimate that maternal genetic contributions account for approximately 30% of the incidence of PTB, and other studies reported fetal gene polymorphism association, to date no consistent associations have been identified. In this study, we performed the largest reported genome-wide association study analysis on 1,349 cases of PTB and 12,595 ancestry-matched controls from the focusing on genomic fetal signals...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29315180/an-in-vitro-insertion-force-study-of-magnetically-guided-lateral-wall-cochlear-implant-electrode-arrays
#17
Lisandro Leon, Frank M Warren, Jake J Abbott
HYPOTHESIS: Insertion forces can be reduced by magnetically guiding the tip of lateral-wall cochlear-implant electrode arrays during insertion via both cochleostomy and the round window. BACKGROUND: Steerable electrode arrays have the potential to minimize intracochlear trauma by reducing the severity of contact between the electrode-array tip and the cochlear wall. However, steerable electrode arrays typically have increased stiffness associated with the steering mechanism...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29315074/precision-accuracy-cross-reactivity-and-comparability-of-serum-indices-measurement-on-abbott-architect-c8000-beckman-coulter-au5800-and-roche-cobas-6000-c501-clinical-chemistry-analyzers
#18
Nora Nikolac Gabaj, Marijana Miler, Alen Vrtarić, Marina Hemar, Petra Filipi, Marija Kocijančić, Vesna Šupak Smolčić, Ivana Ćelap, Ana-Maria Šimundić
BACKGROUND: The aim of our study was to perform verification of serum indices on three clinical chemistry platforms. METHODS: This study was done on three analyzers: Abbott Architect c8000, Beckman Coulter AU5800 (BC) and Roche Cobas 6000 c501. The following analytical specifications were verified: precision (two patient samples), accuracy (sample with the highest concentration of interferent was serially diluted and measured values compared to theoretical values), comparability (120 patients samples) and cross reactivity (samples with increasing concentrations of interferent were divided in two aliquots and remaining interferents were added in each aliquot...
January 9, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29311289/contemporary-sex-based-differences-by-age-in-presenting-characteristics-use-of-an-early-invasive-strategy-and-inhospital-mortality-in-patients-with-non-st-segment-elevation-myocardial-infarction-in-the-united-states
#19
Tanush Gupta, Dhaval Kolte, Sahil Khera, Nayan Agarwal, Pedro A Villablanca, Kashish Goel, Kavisha Patel, Wilbert S Aronow, Jose Wiley, Anna E Bortnick, Herbert D Aronow, J Dawn Abbott, Robert T Pyo, Julio A Panza, Mark A Menegus, Charanjit S Rihal, Gregg C Fonarow, Mario J Garcia, Deepak L Bhatt
BACKGROUND: Prior studies have reported higher inhospital mortality in women versus men with non-ST-segment-elevation myocardial infarction. Whether this is because of worse baseline risk profile compared with men or sex-based disparities in treatment is not completely understood. METHODS AND RESULTS: We queried the 2003 to 2014 National Inpatient Sample databases to identify all hospitalizations in patients aged ≥18 years with the principal diagnosis of non-ST-segment-elevation myocardial infarction...
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29310733/anogenital-distance-in-newborn-daughters-of-women-with-polycystic-ovary-syndrome-indicates-fetal-testosterone-exposure
#20
E S Barrett, K M Hoeger, S Sathyanarayana, D H Abbott, J B Redmon, R H N Nguyen, S H Swan
Polycystic ovary syndrome (PCOS) affects ~7% of reproductive age women. Although its etiology is unknown, in animals, excess prenatal testosterone (T) exposure induces PCOS-like phenotypes. While measuring fetal T in humans is infeasible, demonstrating in utero androgen exposure using a reliable newborn biomarker, anogenital distance (AGD), would provide evidence for a fetal origin of PCOS and potentially identify girls at risk. Using data from a pregnancy cohort (The Infant Development and Environment Study), we tested the novel hypothesis that infant girls born to women with PCOS have longer AGD, suggesting higher fetal T exposure, than girls born to women without PCOS...
January 9, 2018: Journal of Developmental Origins of Health and Disease
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