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https://www.readbyqxmd.com/read/28106355/comparative-study-of-fiberoptic-guided-versus-intubating-laryngeal-mask-airway-assisted-awake-orotracheal-intubation-in-patients-with-unstable-cervical-spine-a-randomized-controlled-trial
#1
Tanmay Jadhav, Kamath Sriganesh, Madhusudan K Reddy, Dhritiman Chakrabarti
BACKGROUND: A safe airway technique minimizes intubation-associated cervical-spine movement and consequent neurological injury in patients with unstable cervical spine (UCS). Awake fiberoptic-guided intubation (FGI) is preferred in patients with UCS. Alternatively, intubating laryngeal mask airway assisted intubation (ILMA-AI) can be performed both during elective and emergency, requires less expertise and is cost-effective. This study evaluated cervical-spine movement during FGI and ILMA-AI in patients with UCS...
January 20, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28098742/does-transection-of-the-c2-nerve-roots-during-c1-lateral-mass-screw-placement-for-atlantoaxial-fixation-result-in-a-superior-outcome-a-systematic-review-of-the-literature-and-meta-analysis
#2
Jetan H Badhiwala, Farshad Nassiri, Christopher D Witiw, Alireza Mansouri, Saleh A Almenawer, Michael G Fehlings
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To evaluate the clinical and functional outcomes of transection of the C2 roots during C1 lateral mass screw placement for atlantoaxial fixation. SUMMARY OF BACKGROUND DATA: Transection of the C2 nerve roots has been recommended during atlantoaxial fixation to facilitate C1 lateral mass screw placement and possibly reduce post-operative occipital neuralgia, although this practice remains controversial...
January 16, 2017: Spine
https://www.readbyqxmd.com/read/28097249/application-of-a-3d-custom-printed-patient-specific-spinal-implant-for-c1-2-arthrodesis
#3
Kevin Phan, Alessandro Sgro, Monish M Maharaj, Paul D'Urso, Ralph J Mobbs
The study aims to describe a three-dimensional printed (3DP) posterior fixation implant used for C1/C2 fusion in a 65-year-old female. Spinal fusion remains a common intervention for a range of spinal pathologies including degenerative disc and facet disease when conservative methods are unsuccessful. However, fusion devices are not always entirely efficacious in providing the desired fixation, and surgeons rely on 'off the shelf' implants which may not provide an anatomical fit to address the particular pathology...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28093348/caudally-directed-inferior-facetal-and-transfacetal-screws-for-c1-c2-and-c1-2-3-fixation
#4
Atul Goel
An alternative caudally directed C2 inferior facetal screw is described. Such screw insertion can form the axial stabilization point in cases undergoing atlantoaxial lateral mass plate/rod and screw fixation and those undergoing C1-2and C1-2-3 spinal fixation. The C2 screw courses from the medial point of pedicle-laminar junction and travels caudally and laterally towards the C2-3 articulation. Deploying a longer screw that traverses in a transarticular fashion into the facetal mass of C3 vertebra one can perform C1-2-3 stabilization...
January 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28056709/deviation-analysis-for-c1-2-pedicle-screw-placement-using-a-three-dimensional-printed-drilling-guide
#5
Xinghuo Wu, Rong Liu, Jie Yu, Lin Lu, Cao Yang, Zengwu Shao, Zhewei Ye
Cervical transarticular fixation is a technically demanding procedure. This study aimed to develop a safer and more accurate method for C1/2 pedicle screw placement using a three-dimensional printed drilling guide. A total of 20 patients with C1/2 fractures and dislocations were recruited, and their computed tomography scans were evaluated. Under the assistance of the three-dimensional printed drilling guide, bilateral C1/2 pedicle screws were successfully placed in the three-dimensional C1/2 models. Then, sagittal and axial computed tomography scans were obtained, and the accuracy and safety of screw placement were evaluated based on X-Y-Z axis setup...
December 1, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28018758/cervical-fracture-subluxation-in-a-patient-with-a-prior-c2-sacrum-fusion-case-report-and-review-of-literature
#6
Yi-Ren Chen, Alvin Y Chan, Kevin K Kumar, Anand Veeravagu
Traumatic injury to an adjacent segment of a previously fused spine is a rare complication of scoliosis surgery. The adjacent spinal segments may be more vulnerable to traumatic fracture or dislocation due to increased strain. We present a patient with prior C2 to sacrum fusion who suffered a C2 fracture/dislocation after falling. A 52-year-old female with a previous C2 to the sacrum fusion for idiopathic scoliosis presented with severe and progressively worsening neck pain after multiple falls. Imaging showed anterior displacement of the C2 vertebral body, fracture of C2, and anterior subluxation of the C1-2 complex on C3...
November 22, 2016: Curēus
https://www.readbyqxmd.com/read/28007383/paralytic-shellfish-toxins-in-phytoplankton-and-shellfish-samples-collected-from-the-bohai-sea-china
#7
Yang Liu, Ren-Cheng Yu, Fan-Zhou Kong, Zhen-Fan Chen, Li Dai, Yan Gao, Qing-Chun Zhang, Yun-Feng Wang, Tian Yan, Ming-Jiang Zhou
Phytoplankton and shellfish samples collected periodically from 5 representative mariculture zones around the Bohai Sea, Laishan (LS), Laizhou (LZ), Hangu (HG), Qinhuangdao (QHD) and Huludao (HLD), were analysed for paralytic shellfish toxins (PSTs) using an high-performance liquid chromatography (HPLC) method. Toxins were detected in 13 out of 20 phytoplankton samples, and N-sulfocarbamoyl toxins (C1/2) were predominant components of PSTs in phytoplankton samples with relatively low toxin content. However, two phytoplankton samples with high PST content collected from QHD and LS had unique toxin profiles characterized by high-potency carbamoyl toxins (GTX1/4) and decarbamoyl toxins (dcGTX2/3 and dcSTX), respectively...
December 19, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27990570/four-mononuclear-platinum-ii-complexes-synthesis-dna-bsa-binding-dna-cleavage-and-cytotoxicity
#8
REVIEW
Qingming Wang, Lei Yang, Jiahui Wu, Hua Wang, Jialiang Song, Xinhui Tang
Four new platinum(II) complexes: Pt(II) L1·H2O (C1, H2 L1 = C20H16N2O2), Pt(II) L2Cl2 (C2, L2 = C22H16N2O2), Pt(II) L3Cl2·H2O (C3, L3 = C20H16N2), Pt(II) L4Cl2·0.4H2O (C4, L4 = C18H14N4) have been synthesized and characterized by using various physico-chemical techniques. The binding interaction of the four platinum(II) complexes C1-C4 with calf thymus (CT)-DNA has been investigated by UV-Vis and fluorescence emission spectrometry. The apparent binding constant (K app) values follow the order: C3 > C1 > C2 > C4...
December 18, 2016: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/27977597/posterior-decompression-and-internal-fixation-in-treatment-of-hypertrophy-of-posterior-longitudinal-ligament-at-c1-2-level-accompanied-with-lower-cervical-spinal-stenosis-a-case-report
#9
Huan Liu, Tao Wang, Hui Wang, Wen-Yuan Ding
RATIONALE: Hypertrophy of posterior longitudinal ligament (HPLL) at C1-2 level accompanied with lower cervical spinal stenosis is rare in clinic. No reports have described HPLL at C1-2 level accompanied with lower cervical spinal stenosis treated by posterior decompression, combined with internal fixation in 1 stage. PATIENT CONCERNS: A 70-year-old Chinese female complained of numbness and paralysis in both her hands and right leg for 1.5 years; Cervical vertebra x-rays and magnetic resonance imaging revealed a HPLL at C1-2 and cervical spinal stenosis at C3-6...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27976585/redox-active-ion-paired-excited-states-undergo-dynamic-electron-transfer
#10
Ludovic Troian-Gautier, Evan E Beauvilliers, Wesley B Swords, Gerald J Meyer
Ion-pair interactions between a cationic ruthenium complex, [Ru(dtb)2(dea)][PF6]2, C1(2+) where dea is 4,4'-diethanolamide-2,2'-bipyridine and dtb is 4,4'-di-tert-butyl-2,2'-bipyridine, and chloride, bromide, and iodide are reported. A remarkable result is that a 1:1 iodide:excited-state ion-pair, [C1(2+), I(-)](+*), underwent diffusional electron-transfer oxidation of iodide that did not occur when ion-pairing was absent. The ion-pair equilibrium constants ranged 10(4)-10(6) M(-1) in CH3CN and decreased in the order Cl(-) > Br(-) > I(-)...
December 28, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27923375/the-surgical-strategy-for-eosinophilic-granuloma-of-the-pediatric-cervical-spine-complicated-with-neurologic-deficit-and-or-spinal-instability
#11
Nanzhe Zhong, Wei Xu, Tong Meng, Xinghai Yang, Wangjun Yan, Jianru Xiao
BACKGROUND: Various therapeutic approaches have been proposed for the treatment of pediatric patients with eosinophilic granuloma (EG) of the cervical spine. Our aim was to discuss and present our experience with the individualized surgical intervention of pediatric cervical EG complicated with neurologic deficits and/or spinal instability. METHODS: We retrospectively analyzed the clinical data of 19 children who were diagnosed with cervical EG comor spinal/or spinal instability (evaluated by the Spinal Instability Neoplastic Score, SINS ≥ 7) and treated surgically in our institution...
December 7, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27890938/chemical-kinetic-model-uncertainty-minimization-through-laminar-flame-speed-measurements
#12
Okjoo Park, Peter S Veloo, David A Sheen, Yujie Tao, Fokion N Egolfopoulos, Hai Wang
Laminar flame speed measurements were carried for mixture of air with eight C3-4 hydrocarbons (propene, propane, 1,3-butadiene, 1-butene, 2-butene, iso-butene, n-butane, and iso-butane) at the room temperature and ambient pressure. Along with C1-2 hydrocarbon data reported in a recent study, the entire dataset was used to demonstrate how laminar flame speed data can be utilized to explore and minimize the uncertainties in a reaction model for foundation fuels. The USC Mech II kinetic model was chosen as a case study...
October 2016: Combustion and Flame
https://www.readbyqxmd.com/read/27858533/revisiting-the-differences-between-irreducible-and-reducible-atlantoaxial-dislocation-in-the-era-of-direct-posterior-approach-and-c1-2-joint-manipulation
#13
Arsikere N Deepak, Pravin Salunke, Sushanta K Sahoo, Prashant K Prasad, Niranjan K Khandelwal
OBJECTIVE The current management of atlantoaxial dislocation (AAD) focuses on the C1-2 joints, commonly approached through a posterior route. The distinction between reducible AAD (RAAD) and irreducible AAD (IrAAD) seems to be less important in modern times. The roles of preoperative traction and dynamic radiographs are questionable. This study evaluated whether differentiating between the 2 groups is important in today's era. METHODS Ninety-six consecutive patients with congenital AAD (33 RAAD and 63 IrAAD), who underwent surgery through a posterior approach alone, were studied...
November 18, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27857933/retro-odontoid-pseudotumor-without-atlantoaxial-subluxation-or-rheumatic-arthritis
#14
Seung Han Yu, Hyuk Jin Choi, Won Ho Cho, Seung Heon Cha, In Ho Han
We present a case of retro-odontoid pseudotumor (ROP) without rheumatoid arthritis (RA) or atlantoaxial subluxation (AAS). A 76-year-old woman presented with paresthesia and weakness of both lower and upper extremities. She had no laboratory or physical findings of RA. Dynamic X-ray showed no AAS and magnetic resonance imaging (MRI) showed a retro-odontoid mass compressing the spinal cord. Transdural mass debulking and biopsy were performed via minimal left suboccipital craniectomy and C1 hemilaminectomy. Two months after surgery, her symptoms were aggravated...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27847133/c1-lateral-mass-screw-insertion-caudally-from-c2-nerve-root-an-alternate-method-for-insertion-of-c1-screws-a-technical-note-and-preliminary-clinical-results
#15
Keiji Wada, Ryo Tamaki, Mitsuru Yui, Daisuke Numaguchi, Yasuaki Murata
BACKGROUND: C1 lateral mass screw was widely used for fixation of the upper cervical spine. However, massive bleeding from the C1-2 venous plexus is sometimes encountered. In this study, we proposed an alternate method for C1 lateral mass screw insertion, which involves insertion of the screws caudally from the C2 nerve root to reduce bleeding from C1-2 venous plexus. METHODS: Seven patients with atlantoaxial lesions were included in this study. The mean age at surgery was 65...
November 12, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/27813142/citrate-metabolism-in-red-blood-cells-stored-in-additive-solution-3
#16
Angelo D'Alessandro, Travis Nemkov, Tatsuro Yoshida, Aarash Bordbar, Bernhard O Palsson, Kirk C Hansen
BACKGROUND: Red blood cells (RBCs) are thought to have a relatively simple metabolic network compared to other human cell types. Recent proteomics reports challenge the notion that RBCs are mere hemoglobin carriers with limited metabolic activity. Expanding our understanding of RBC metabolism has key implications in many biomedical areas, including transfusion medicine. STUDY DESIGN AND METHODS: In-gel digestion coupled with mass spectrometric analysis proteomics approaches were combined with state-of-the-art tracing experiments by incubating leukofiltered RBCs in additive solution-3 for up to 42 days under blood bank conditions, in presence of (13) C1,2,3 -glucose, 2,2,4,4-d-citrate, and (13) C,(15) N-glutamine...
November 4, 2016: Transfusion
https://www.readbyqxmd.com/read/27811129/palliative-ct-guided-cordotomy-for-medically-intractable-pain-in-patients-with-cancer
#17
T M Shepherd, M J Hoch, B A Cohen, M T Bruno, E Fieremans, G Rosen, D Pacione, A Y Mogilner
Palliative cervical cordotomy can be performed via percutaneous radiofrequency ablation of the lateral C1-2 spinothalamic tract. This rare procedure can be safe, effective, and advantageous in mitigating medically intractable unilateral extremity pain for selected patients with end-stage cancer. This report reviews the indications, techniques, risks, and potential benefits of cordotomy. We describe our recent experience treating 3 patients with CT-guided C1-2 cordotomy and provide the first characterization of spinal cord diffusion MR imaging changes associated with successful cordotomy...
November 3, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27790327/challenges-of-transarticular-screw-fixation-in-young-children-report-of-surgical-treatment-of-a-5-year-old-patient-s-unstable-os-odontoideum
#18
Jun Takahashi, Hiroki Hirabayashi, Hiroyuki Hashidate, Nobuhide Ogihara, Keijiro Mukaiyama, Masatoshi Komatsu, Yuji Inaba, Tomoki Kosho, Hiroyuki Kato
Surgical procedures for atlantoaxial (C1-C2) fusion in young children are relatively uncommon. The purpose of this study was to report on a surgical treatment for a case of atlantoaxial instability caused by os-odontoideum in association with quadriparesis and respiratory paralysis in a 5-year-old girl. We present the patient's history, physical examination, and radiographic findings, describe the surgical treatment and a five year follow-up, and provide a literature review. The instability was treated by halo immobilization, followed by C1-C2 transarticular screw fixation using a computed tomography-based navigation system...
October 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27787362/a-novel-method-of-c1-c2-transarticular-screw-insertion-for-symptomatic-atlantoaxial-instability-using-a-customized-guiding-block-a-case-report-and-a-technical-note
#19
Kuo-Yuan Huang, Ruey-Mo Lin, Jing-Jing Fang
Atlantoaxial instability treated with the C1-2 transarticular screw fixation is biomechanically more stable; however, the technique demanding and the potential risk of neurovascular injury create difficulties for clinical usage, and there is still lack of clinical experience till now.We reported an adult female patient with symptomatic atlantoaxial instability due to rheumatoid arthritis that was successfully treated with a bilateral C1-C2 transarticular screw fixation using a customized guiding block. We preoperatively determined the trajectories for bilateral C1-C2 transarticular screws on a 3-dimensional reconstruction model from the computed tomography (CT) and self-developed computer software, and designed a rapid prototyping customized guiding block in order to offer a guide for the entry point and insertion angle of the C1-C2 transarticular screws...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27774668/bio-and-chemical-syntheses-of-mangiferin-and-congeners
#20
REVIEW
Teddy Stephen Ehianeta, Stéphane Laval, Biao Yu
Mangiferin (2C-β-d-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone) is a xanthone C-glycoside occurring in many plant species. Composed of a glucose unit C1→2 linked to a 1,3,6,7-tetrahydroxyxanthone aglycone, mangiferin exhibits a wide range of biological activities, which recently renewed its interest as a potential pharmacophore. Mangiferin is mainly isolated after extraction procedures from natural sources alongside with its isoforms isomangiferin, homomangiferin, and neomangiferin. However, enzymatic and chemical approaches have been developed to access these phytochemicals, which address the challenging construction of the C-glycosidic linkage...
September 10, 2016: BioFactors
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