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https://www.readbyqxmd.com/read/28685403/the-change-of-cervical-spine-alignment-along-with-aging-in-asymptomatic-population-a-preliminary-analysis
#1
Yiwei Chen, Jiaquan Luo, Zhimin Pan, Limin Yu, Long Pang, Junlong Zhong, Zhiyun Li, Zhimin Han, Kai Cao
STUDY DESIGN: A cross-sectional study. OBJECTIVE: To investigate the correlation of cervical spine alignment changes with aging in asymptomatic population. BACKGROUND: Previous studies demonstrated the influence of lumbar and thoracic spine on cervical spine alignment, but few has reported the cervical spine alignment change along with aging in asymptomatic population. METHODS: Asymptomatic population were divided into four groups according to different ages (Group A: ≤20 years; Group B: 21-40 years; Group C: 41-60 years; Group D: ≥61 years)...
July 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28678026/transoral-closed-reduction-of-fixed-atlanto-axial-rotatory-subluxation-aars-in-childhood-and-adolescence
#2
Dezsoe Jeszenszky, Tamas Fekete, Frank Kleinstück, Daniel Haschtmann, Markus Loibl
Atlanto-axial rotatory-subluxation (AARS) is the most common pediatric cervical spine injury. Patients usually present with contralateral rotation and inclination of the upper cervical spine after minor trauma, or associated with an infection of the upper respiratory tract. According to the authors, initial management of patients with acute and chronic AARS type I-II should comprise closed reduction and immobilization with a cervical collar or a Halo-Body-Jacket. Surgical options of open reduction or C1/2 fusion should be restricted to irreducible or recurrent subluxations...
July 3, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28662472/stepwise-unfolding-of-ribonuclease-a-by-a-biosurfactant
#3
Bijan K Paul, Riya Sett, Nikhil Guchhait
The interaction of Ribonuclease A (RNase A) with the bile salt, sodium deoxycholate (NaDC) is meticulously investigated using various spectroscopic techniques. The binding isotherm constructed from the modulation of intrinsic tyrosine fluorescence of the protein following interaction with NaDC conspicuously reveals an intrinsically complex stepwise interaction process which proceeds through the formation of distinct conformational states of the protein. The conformational transitions are found to occur at c1=2...
June 19, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28658978/surgical-considerations-in-posterior-c1-2-instrumentation-in-the-presence-of-vertebral-artery-anomalies-case-illustration-and-review-of-literature
#4
Lee A Tan, Manish K Kasliwal, Carter S Gerard, Vincent C Traynelis, Ricardo B V Fontes
Vascular anomalies involving the V3 segment of the vertebral artery are common and may complicate posterior atlantoaxial instrumentation. We report a patient with a fenestrated vertebral artery that underwent successful C1-2 instrumentation and fusion. Various vertebral artery anomalies are discussed with a review of pertinent literature.
June 29, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28634360/missing-magnetism-in-sr4ru3o10-indication-for-antisymmetric-exchange-interaction
#5
Franziska Weickert, Leonardo Civale, Boris Maiorov, Marcelo Jaime, Myron B Salamon, Emanuela Carleschi, André M Strydom, Rosalba Fittipaldi, Veronica Granata, Antonio Vecchione
Metamagnetism occuring inside a ferromagnetic phase is peculiar. Therefore, Sr4Ru3O10, a T C  = 105 K ferromagnet, has attracted much attention in recent years, because it develops a pronounced metamagnetic anomaly below T C for magnetic fields applied in the crystallographic ab-plane. The metamagnetic transition moves to higher fields for lower temperatures and splits into a double anomaly at critical fields H c1 = 2.3 T and H c2 = 2.8 T, respectively. Here, we report a detailed study of the different components of the magnetization vector as a function of temperature, applied magnetic field, and varying angle in Sr4Ru3O10...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28627291/early-complications-morbidity-and-mortality-in-octo-and-nonagenarians-undergoing-posterior-intraoperative-spinal-navigation-based-c1-2-fusion-for-type-ii-odontoid-process-fractures
#6
Basem Ishak, Till Schneider, Valerie Gimmy, Andreas W Unterberg, Karl L Kiening
Type II odontoid fractures represent the most common cervical spine injury in the elderly. The decision for surgical treatment is still controversial, particularly with regard to the elevated perioperative risk attributed to frequent comorbidities and poor bone quality. Purpose of this study was to assess both short-term mortality and mid-term clinical and radiological outcome in the elderly. Between January 2007 and December 2015, 35 patients with type II odontoid process fractures who underwent posterior atlanto-axial instrumentation using a modified Goel-Harms technique were retrospectively analyzed and prospectively examined clinically and radiologically...
June 18, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28622000/observation-of-%C3%AF-3686-%C3%A2-e-e-%C3%AF-_-cj-and-%C3%AF-_-cj-%C3%A2-e-e-j-%C3%AF
#7
M Ablikim, M N Achasov, X C Ai, O Albayrak, M Albrecht, D J Ambrose, A Amoroso, F F An, Q An, J Z Bai, R Baldini Ferroli, Y Ban, D W Bennett, J V Bennett, M Bertani, D Bettoni, J M Bian, F Bianchi, E Boger, I Boyko, R A Briere, H Cai, X Cai, O Cakir, A Calcaterra, G F Cao, S A Cetin, J F Chang, G Chelkov, G Chen, H S Chen, H Y Chen, J C Chen, M L Chen, S Chen, S J Chen, X Chen, X R Chen, Y B Chen, H P Cheng, X K Chu, G Cibinetto, H L Dai, J P Dai, A Dbeyssi, D Dedovich, Z Y Deng, A Denig, I Denysenko, M Destefanis, F De Mori, Y Ding, C Dong, J Dong, L Y Dong, M Y Dong, Z L Dou, S X Du, P F Duan, J Z Fan, J Fang, S S Fang, X Fang, Y Fang, R Farinelli, L Fava, O Fedorov, F Feldbauer, G Felici, C Q Feng, E Fioravanti, M Fritsch, C D Fu, Q Gao, X L Gao, X Y Gao, Y Gao, Z Gao, I Garzia, K Goetzen, L Gong, W X Gong, W Gradl, M Greco, M H Gu, Y T Gu, Y H Guan, A Q Guo, L B Guo, R P Guo, Y Guo, Y P Guo, Z Haddadi, A Hafner, S Han, X Q Hao, F A Harris, K L He, T Held, Y K Heng, Z L Hou, C Hu, H M Hu, J F Hu, T Hu, Y Hu, G S Huang, J S Huang, X T Huang, X Z Huang, Y Huang, Z L Huang, T Hussain, Q Ji, Q P Ji, X B Ji, X L Ji, L W Jiang, X S Jiang, X Y Jiang, J B Jiao, Z Jiao, D P Jin, S Jin, T Johansson, A Julin, N Kalantar-Nayestanaki, X L Kang, X S Kang, M Kavatsyuk, B C Ke, P Kiese, R Kliemt, B Kloss, O B Kolcu, B Kopf, M Kornicer, A Kupsc, W Kühn, J S Lange, M Lara, P Larin, C Leng, C Li, Cheng Li, D M Li, F Li, F Y Li, G Li, H B Li, H J Li, J C Li, Jin Li, K Li, K Li, Lei Li, P R Li, Q Y Li, T Li, W D Li, W G Li, X L Li, X N Li, X Q Li, Y B Li, Z B Li, H Liang, Y F Liang, Y T Liang, G R Liao, D X Lin, B Liu, B J Liu, C X Liu, D Liu, F H Liu, Fang Liu, Feng Liu, H B Liu, H H Liu, H H Liu, H M Liu, J Liu, J B Liu, J P Liu, J Y Liu, K Liu, K Y Liu, L D Liu, P L Liu, Q Liu, S B Liu, X Liu, Y B Liu, Z A Liu, Zhiqing Liu, H Loehner, X C Lou, H J Lu, J G Lu, Y Lu, Y P Lu, C L Luo, M X Luo, T Luo, X L Luo, X R Lyu, F C Ma, H L Ma, L L Ma, M M Ma, Q M Ma, T Ma, X N Ma, X Y Ma, Y M Ma, F E Maas, M Maggiora, Y J Mao, Z P Mao, S Marcello, J G Messchendorp, J Min, R E Mitchell, X H Mo, Y J Mo, C Morales Morales, N Yu Muchnoi, H Muramatsu, Y Nefedov, F Nerling, I B Nikolaev, Z Ning, S Nisar, S L Niu, X Y Niu, S L Olsen, Q Ouyang, S Pacetti, Y Pan, P Patteri, M Pelizaeus, H P Peng, K Peters, J Pettersson, J L Ping, R G Ping, R Poling, V Prasad, H R Qi, M Qi, S Qian, C F Qiao, L Q Qin, N Qin, X S Qin, Z H Qin, J F Qiu, K H Rashid, C F Redmer, M Ripka, G Rong, Ch Rosner, X D Ruan, A Sarantsev, M Savrié, K Schoenning, S Schumann, W Shan, M Shao, C P Shen, P X Shen, X Y Shen, H Y Sheng, M Shi, W M Song, X Y Song, S Sosio, S Spataro, G X Sun, J F Sun, S S Sun, X H Sun, Y J Sun, Y Z Sun, Z J Sun, Z T Sun, C J Tang, X Tang, I Tapan, E H Thorndike, M Tiemens, M Ullrich, I Uman, G S Varner, B Wang, B L Wang, D Wang, D Y Wang, K Wang, L L Wang, L S Wang, M Wang, P Wang, P L Wang, S G Wang, W Wang, W P Wang, X F Wang, Y Wang, Y D Wang, Y F Wang, Y Q Wang, Z Wang, Z G Wang, Z H Wang, Z Y Wang, Z Y Wang, T Weber, D H Wei, J B Wei, P Weidenkaff, S P Wen, U Wiedner, M Wolke, L H Wu, L J Wu, Z Wu, L Xia, L G Xia, Y Xia, D Xiao, H Xiao, Z J Xiao, Y G Xie, Q L Xiu, G F Xu, J J Xu, L Xu, Q J Xu, Q N Xu, X P Xu, L Yan, W B Yan, W C Yan, Y H Yan, H J Yang, H X Yang, L Yang, Y X Yang, M Ye, M H Ye, J H Yin, B X Yu, C X Yu, J S Yu, C Z Yuan, W L Yuan, Y Yuan, A Yuncu, A A Zafar, A Zallo, Y Zeng, Z Zeng, B X Zhang, B Y Zhang, C Zhang, C C Zhang, D H Zhang, H H Zhang, H Y Zhang, J Zhang, J J Zhang, J L Zhang, J Q Zhang, J W Zhang, J Y Zhang, J Z Zhang, K Zhang, L Zhang, S Q Zhang, X Y Zhang, Y Zhang, Y H Zhang, Y N Zhang, Y T Zhang, Yu Zhang, Z H Zhang, Z P Zhang, Z Y Zhang, G Zhao, J W Zhao, J Y Zhao, J Z Zhao, Lei Zhao, Ling Zhao, M G Zhao, Q Zhao, Q W Zhao, S J Zhao, T C Zhao, Y B Zhao, Z G Zhao, A Zhemchugov, B Zheng, J P Zheng, W J Zheng, Y H Zheng, B Zhong, L Zhou, X Zhou, X K Zhou, X R Zhou, X Y Zhou, K Zhu, K J Zhu, S Zhu, S H Zhu, X L Zhu, Y C Zhu, Y S Zhu, Z A Zhu, J Zhuang, L Zotti, B S Zou, J H Zou
Using 4.479×10^{8}  ψ(3686) events collected with the BESIII detector, we search for the decays ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ, where J=0, 1, 2. The decays ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ are observed for the first time. The measured branching fractions are B(ψ(3686)→e^{+}e^{-}χ_{cJ})=(11.7±2.5±1.0)×10^{-4}, (8.6±0.3±0.6)×10^{-4}, (6.9±0.5±0.6)×10^{-4} for J=0, 1, 2, and B(χ_{cJ}→e^{+}e^{-}J/ψ)=(1.51±0.30±0.13)×10^{-4}, (3.73±0...
June 2, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28616930/-a-study-of-etiology-classification-of-minor-stroke-based-on-toast-and-asco-systems
#8
Jie Zhou, Yang Zhang, Yi-Jia Guo, Li He
OBJECTIVES: To investigate the differences in the etiology between minor stroke and non-minor stroke based on TOAST and ASCO systems, and to guide the early intervention for minor stroke. METHODS: We retrospectively analyzed the patients with acute ischemic stroke admitted to our department from July 2012 to July 2014. We sub-typed minor stroke patients and non-minor stroke patients in etiology using Trial of Org 10172 in Acute Stroke Treatment (TOAST) and ASCO (A for atherosclerosis, S for small vessel disease, C for Cardiac source, O for other cause) systems respectively to investigate the difference of etiology between the two groups...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28612321/the-changing-shape-of-the-iscev-standard-pattern-onset-vep
#9
Dorothy A Thompson, Dennis M Fritsch, Sharon E Hardy
PURPOSE: Pattern onset VEPs do not always show distinct C1-C2-C3 peaks and troughs. Our purpose was to study changes in pattern onset VEP with age to determine when the illustrated ISCEV standard onset VEP waveform can be reliably recorded. METHODS: We recorded pattern onset VEPs from an Oz electrode referred to mid-frontal electrode according to ISCEV standards by presenting checks of 60' and 15' side length in a 15° field. Twenty-four adults aged 20-63 years participated...
June 13, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28601895/site-saturation-mutagenesis-library-construction-and-screening-for-specific-broad-spectrum-single-domain-antibodies-against-multiple-cry1-toxins
#10
Lingxia Jiao, Yuan Liu, Xiao Zhang, Beibei Liu, Cunzheng Zhang, Xianjin Liu
Potential ecological environmental and food safety risks of various Cry toxins of Bacillus thuringiensis (Bt) in transgenic food have received gradually increasing attention, which urged to establish an efficient and broad-spectrum detection technology for Cry toxins. Based on the single-domain antibody (sdAb) A8 against Bt Cry1Ab toxin screened from the humanized domain antibody library, the key amino acids of sdAb (A8) binding five kinds of Cry1 toxins were predicted using homology modeling and molecular docking technology, and the results showed that 105th asparagine, 106th arginine, 107th valine, and 114th arginine, respectively, located in heavy-chain complementarity-determining region 3 were common key amino acid sites...
June 11, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28598291/spinal-navigation-for-posterior-instrumentation-of-c1-2-instability-using-a-mobile-intraoperative-ct-scanner
#11
Marcus Czabanka, Julien Haemmerli, Nils Hecht, Bettina Foehre, Klaus Arden, Thomas Liebig, Johannes Woitzik, Peter Vajkoczy
OBJECTIVE Spinal navigation techniques for surgical fixation of unstable C1-2 pathologies are challenged by complex osseous and neurovascular anatomy, instability of the pathology, and unreliable preoperative registration techniques. An intraoperative CT scanner with autoregistration of C-1 and C-2 promises sufficient accuracy of spinal navigation without the need for further registration procedures. The aim of this study was to analyze the accuracy and reliability of posterior C1-2 fixation using intraoperative mobile CT scanner-guided navigation...
June 9, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28548597/william-edward-gallie-1882-1959-father-of-the-gallie-wiring-technique-for-atlantoaxial-arthrodesis
#12
Rimal Hanif Dossani, John Shaughnessy, Piyush Kalakoti, Anil Nanda
William Edward Gallie (1882-1959) was a Canadian general surgeon with special expertise in orthopedic surgery. His experience with surgical management of cervical spine subluxation led him to invent a method of cervical wiring of the atlas to the axis. His method of C1-2 wiring has since been modified, but it still remains one of the three most commonly taught wiring techniques in neurosurgical training programs. Gallie is also hailed for instituting the first surgical training program in Canada, a curriculum his pupils memorialized as the "Gallie course" in surgery...
May 26, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28536356/hla-c-kir-ligands-determine-the-impact-of-anti-thymocyte-globulin-atg-on-graft-versus-host-and-graft-versus-leukemia-effects-following-hematopoietic-stem-cell-transplantation
#13
Johannes Clausen, Alexandra Böhm, Irene Straßl, Olga Stiefel, Veronika Buxhofer-Ausch, Sigrid Machherndl-Spandl, Josef König, Stefan Schmidt, Hansjörg Steitzer, Martin Danzer, Hedwig Kasparu, Ansgar Weltermann, David Nachbaur
Rabbit anti-thymocyte globulins (ATGs) are widely used for the prevention of acute and chronic graft versus host disease (aGVHD, cGVHD) following allogeneic hematopoietic stem cell transplantation (HSCT). However, most prospective and retrospective studies did not reveal an overall survival (OS) benefit associated with ATG. Homozygosity for human leukocyte antigen (HLA)-C group 1 killer-cell immunoglobulin-like receptor ligands (KIR-L), i.e. C1/1 KIR-L status, was recently shown to be a risk factor for severe aGVHD...
March 28, 2017: Biomedicines
https://www.readbyqxmd.com/read/28527346/inhibitory-effects-of-2-oxo-2h-chromen-4-yl-4-methylbenzenesulfonate-on-allergic-inflammatory-responses-in-rat-basophilic-leukemia-cells
#14
Gaeun Yoo, Kooyeon Lee, Deug-Chan Lee
Mast cells play crucial roles in the initiation of allergic inflammatory responses by releasing various mediators such as histamines, cytokines, and leukotrienes. In addition, signaling cascade pathways, such as the mitogen-activated protein kinase (MAPK) pathway, contribute to the regulation of mast cell degranulation. Accordingly, different research strategies have been pursued to develop anti-inflammatory and anti-allergic drugs by regulating these signaling pathways. The development of new drugs that inhibit mast cell degranulation may help in the treatment of allergies...
May 17, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28512615/delayed-infarction-of-medullar-and-cerebellum-3-months-after-vertebral-artery-injury-with-c1-2-fracture-case-report
#15
Yunsuk Her, Suk Hyung Kang, Ilhom Abdullaev, Noah Kim
The clinical manifestations of vertebral artery (VA) injury (VAI) after cervical trauma range from asymptomatic to fatal cerebral infarction. Thrombotic occlusion and embolization to the distal arteries can cause cerebellar and brain stem infarction within days after trauma. We report a 64-year-old man who underwent arthrodesis surgery for C1 and C2 fractures. He had left VAI at the C2 transverse foramen site but was asymptomatic. The patient experiences brainstem and cerebellar infarction 3 months after injury to the VA, and we are here to discuss the treatment of VAI after cervical trauma...
April 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/28478911/epithelioid-hemangioendothelioma-of-the-craniocervical-junction-case-report-and-review
#16
Ali Ender Ofluoglu, Mehmet Aydogan, Uzay Erdogan, Onder Ofluoglu
Epithelioid hemangioendotheliomas are uncommon vascular neoplasms and their spinal location is even rarer. We report clinical course of a 31-year-old man with an epithelioid hemangioendothelioma at the cranio-cervical junction. A cervical magnetic resonance imaging revealed tumor that caused posterior cervical cord compression. C1,2,3 total laminectomy and surgical excision of the tumor was performed. Postoperative external beam radiation was performed on the surgical field especially around the right vertebral artery...
May 3, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28472514/evaluating-atlantoaxial-dislocation-based-on-cartesian-coordinates-proposing-a-new-definition-and-its-impact-on-assessment-of-congenital-torticollis
#17
Jayesh Sardhara, Sanjay Behari, Pavaman Sindgikar, Arun Kumar Srivastava, Anant Mehrotra, Kuntal Kanti Das, Kamlesh Singh Bhaisora, Rabi N Sahu, Awadhesh K Jaiswal
BACKGROUND: Conventional 2-dimensional (2-D) definition of atlantoaxial dislocation (AAD) is inadequate for coexisting 3-D displacements. OBJECTIVE: To prospectively classify AAD and its related abnormalities along 3 Cartesian coordinates and assess their association with torticollis. METHODS: One hundred and fifty-four patients with congenital AAD were prospectively classified according to their C1-2 displacement along 3 Cartesian coordinates utilizing 3-D multiplanar CT...
May 3, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28451859/effect-of-correction-surgery-for-cervical-kyphosis-on-compensatory-mechanisms-in-overall-spinopelvic-sagittal-alignment
#18
Hiroshi Miyamoto, Kazuki Hashimoto, Terumasa Ikeda, Masao Akagi
PURPOSE: Progression of kyphotic deformity at the middle/lower cervical spine can cause difficulty with horizontal gaze, so compensation at other spinopelvic parts may occur. However, the precise mechanism remains unclear. The present study investigated the effect of correction surgery for cervical kyphosis on the compensatory mechanisms in overall spinopelvic sagittal alignment. METHODS: Forty-one patients, comprising 23 males and 18 females (mean age 67 years), underwent correction surgery for cervical kyphosis using the posterior screw-rod system...
April 27, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28409288/temporary-fusionless-posterior-occipitocervical-fixation-for-a-proximal-junctional-type-ii-odontoid-fracture-after-previous-c2-pelvis-fusion-case-report-description-of-a-new-surgical-technique-and-review-of-the-literature
#19
Alexander A Theologis, Vedat Deviren, Bobby Tay
PURPOSE: Axial fractures in patients with a previous C2-pelvis posterior instrumented fusion are rare and may be challenging to manage. Motion preservation in the axial spine for these patients is important, as the C1-2 and Occipit-C1 joints are their only remaining mobile spinal segments. In this unique report, we present for the first time the use of a fusionless occipitocervical operation for the treatment of a type II odontoid fracture and unilateral C2 pars fracture adjacent to a previous C2-pelvis posterior instrumented fusion...
May 2017: European Spine Journal
https://www.readbyqxmd.com/read/28383091/a-new-technique-for-the-surgical-treatment-of-atlantoaxial-instability-c1-lateral-mass-and-c2-3-transfacet-screwing
#20
Salim Senturk, Goktug Akyoldas, Onur Yaman, Ali Fahir Ozer
AIM: Atlantoaxial instability is a special entity that may be caused by many disorders such as trauma, tumor, arthritis, congenital malformation and infection. Atlantoaxial fixation is needed to provide stability, prevent neurological deficits and correct deformity. The objective of this study is to introduce an alternative technique for the treatment of atlantoaxial instability in patients who have vertebral artery anomaly, anomalous C2 or osteoporosis. MATERIAL AND METHODS: C1-2-3 fixation was performed in a 50-years-old, male patient with atlantoaxial instability due to os odontoideum...
March 9, 2017: Turkish Neurosurgery
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