keyword
https://read.qxmd.com/read/38628869/scenario-based-assessment-of-fecal-pathogen-sources-affecting-bathing-water-quality-novel-treatment-options-to-reduce-norovirus-and-campylobacter-infection-risks
#21
JOURNAL ARTICLE
Annastiina Rytkönen, Päivi Meriläinen, Kristiina Valkama, Anna-Maria Hokajärvi, Josefiina Ruponen, Jarkko Nummela, Harri Mattila, Tiina Tulonen, Rauni Kivistö, Tarja Pitkänen
Wastewater discharge and runoff waters are significant sources of human and animal fecal microbes in surface waters. Human-derived fecal contamination of water is generally estimated to pose a greater risk to human health than animal fecal contamination, but animals may serve as reservoirs of zoonotic pathogens. In this study, quantitative microbial risk assessment (QMRA) tools were used to evaluate the hygienic impact of sewage effluents and runoff water from municipalities and animal farms on surface and bathing waters...
2024: Frontiers in Microbiology
https://read.qxmd.com/read/38628211/the-multifaceted-potential-of-fenugreek-seeds-from-health-benefits-to-food-and-nanotechnology-applications
#22
REVIEW
Zargham Faisal, Rushba Irfan, Noor Akram, Hafiz Muhammad Irfan Manzoor, Mohib Ali Aabdi, Muhammad Junaid Anwar, Sharjeel Khawar, Asifa Saif, Yasir Abbas Shah, Muhammad Afzaal, Derese Tamiru Desta
The present lifestyle, dietary patterns, psychological pressure, environmental factors, and the widespread exploitation of processed substances in food production and farming have collectively contributed to a substantial expediting in the development of various health problems. Globally, researchers have been seeking natural pharmaceutical substances with the potential to be employed in treating lifestyle-related diseases or delaying their onset. Fenugreek seeds have gained significant attention in various fields, including health, nutrition, and cutting-edge nanotechnology applications, due to their versatile qualities...
April 2024: Food Science & Nutrition
https://read.qxmd.com/read/38627827/national-genomic-epidemiology-investigation-revealed-the-spread-of-carbapenem-resistant-escherichia-coli-in-healthy-populations-and-the-impact-on-public-health
#23
JOURNAL ARTICLE
Yan Li, Yanyan Zhang, Xinran Sun, Yuchen Wu, Zelin Yan, Xiaoyang Ju, Yonglu Huang, Hongwei Zhou, Zhiqiang Wang, Shaolin Wang, Rong Zhang, Ruichao Li
BACKGROUND: Carbapenem-resistant Escherichia coli (CREC) has been considered as WHO priority pathogens, causing a great public health concern globally. While CREC from patients has been thoroughly investigated, the prevalence and underlying risks of CREC in healthy populations have been overlooked. Systematic research on the prevalence of CREC in healthy individuals was conducted here. We aimed to characterize CREC collected from healthy populations in China between 2020 and 2022 and to compare the genomes of CREC isolates isolated from healthy individuals and clinical patients...
April 16, 2024: Genome Medicine
https://read.qxmd.com/read/38627425/analytic-representative-element-rate-decline-models-for-naturally-fractured-reservoir-depletion
#24
JOURNAL ARTICLE
R D Hazlett, T Syrymov, R Younis
Representative single anisotropic matrix block 2D Green's function models for depletion through fully-penetrating, vertical fractures through different numbers of fracture faces are constructed that analytically capture both fracture and block depletion with fracture-matrix mass transfer. The 1D Green's function for a fracture system is likewise solved in terms of the time evolution of average fracture pressure. While transient average pressure values are not inherently measurable, they are transformed into cumulative production or instantaneous flowrate values, thus producing new rate decline model functional forms...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38627413/reconfigurable-optoelectronic-transistors-for-multimodal-recognition
#25
JOURNAL ARTICLE
Pengzhan Li, Mingzhen Zhang, Qingli Zhou, Qinghua Zhang, Donggang Xie, Ge Li, Zhuohui Liu, Zheng Wang, Erjia Guo, Meng He, Can Wang, Lin Gu, Guozhen Yang, Kuijuan Jin, Chen Ge
Biological nervous system outperforms in both dynamic and static information perception due to their capability to integrate the sensing, memory and processing functions. Reconfigurable neuromorphic transistors, which can be used to emulate different types of biological analogues in a single device, are important for creating compact and efficient neuromorphic computing networks, but their design remains challenging due to the need for opposing physical mechanisms to achieve different functions. Here we report a neuromorphic electrolyte-gated transistor that can be reconfigured to perform physical reservoir and synaptic functions...
April 16, 2024: Nature Communications
https://read.qxmd.com/read/38627263/clinical-characteristics-and-pathogen-spectrum-of-male-genital-fungal-infections-in-nanchang-area-south-china
#26
JOURNAL ARTICLE
Yun Jin, Yangmin Gao, Yunpeng Luo, XiaoHua Tao, Qing Jiang, Xinyi Fan, Rui Xu, Hua Qian, Xiaoguang Li, Zhijun Zhou
The cutaneous fungal infections in male genitalia are relatively rare, and often present with various atypical clinical symptoms. It was mainly reported in a small number of case reports, while data with large number of patients were rarely reported. In this study, we reported 79 male patients with cutaneous fungal infections on scrotum or penis. The fungal infections were confirmed by microscopic examination directly and fungus culture. Clinical characteristics and predisposing factors were also collected...
April 16, 2024: Mycopathologia
https://read.qxmd.com/read/38626821/geomechanics-contribution-to-co-2-storage-containment-and-trapping-mechanisms-in-tight-sandstone-complexes-a-case-study-on-mae-moh-basin
#27
JOURNAL ARTICLE
Romal Ramadhan, Khomchan Promneewat, Vorasate Thanasaksukthawee, Teerapat Tosuai, Masoud Babaei, Seyyed A Hosseini, Avirut Puttiwongrak, Cheowchan Leelasukseree, Suparit Tangparitkul
Recognized as a not-an-option approach to mitigate the climate crisis, carbon dioxide capture and storage (CCS) has a potential as much as gigaton of CO2 to sequestrate permanently and securely. Recent attention has been paid to store highly concentrated point-source CO2 into saline formation, of which Thailand considers one onshore case in the north located in Lampang - the Mae Moh coal-fired power plant matched with its own coal mine of Mae Moh Basin. Despite a large basin and short transport route from the source, target sandstone reservoir buried at deeper than 1000 m is of tight nature and limited data, while question on storing possibility has thereafter risen...
April 14, 2024: Science of the Total Environment
https://read.qxmd.com/read/38626749/prevalence-and-characteristics-of-plasmodium-vivax-gametocytes-in-duffy-positive-and-duffy-negative-populations-across-ethiopia
#28
JOURNAL ARTICLE
Ebony Little, Tassew T Shenkutie, Meshesha Tsigie Negash, Beka R Abagero, Abnet Abebe, Jean Popovici, Sindew Mekasha Feleke, Eugenia Lo
Plasmodium parasites replicate asexually in human hosts. The proportion of infections that carries gametocytes is a proxy for human-to-mosquito transmissibility. It is unclear which proportion of Plasmodium vivax infections in Duffy-negative populations carries gametocytes. We determined the prevalence and characteristics of P. vivax gametocytes in Duffy-positive and -negative populations across broad regions of Ethiopia. Finger-prick blood samples were collected for microscopic and molecular screening of Plasmodium parasites and Duffy status of individuals...
April 16, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38626680/eco-friendly-management-of-harmful-cyanobacterial-blooms-in-eutrophic-lakes-through-vertical-flow-multi-soil-layering-technology
#29
JOURNAL ARTICLE
Roseline Prisca Aba, Sofyan Sbahi, Richard Mugani, El Mahdi Redouane, Abdessamad Hejjaj, Joana Azevedo, Cristiana Ivone Tavares Moreira, Sergio Fernández Boo, Diogo Alves Da Mota Alexandrino, Alexandre Campos, Vitor Vasconcelos, Brahim Oudra, Naaila Ouazzani, Laila Mandi
Eutrophication has led to the widespread occurrence of cyanobacterial blooms. Toxic cyanobacterial blooms with high concentrations of microcystins (MCs) have been identified in the Lalla Takerkoust reservoir in Morocco. The objective of this study was to evaluate the efficiency of the Multi-Soil-Layering (MSL) ecotechnology in removing natural cyanobacterial blooms from the lake. Two MSL pilots were used in rectangular glass tanks (60 × 10 × 70 cm). They consisted of permeable layers (PLs) made of pozzolan and a soil mixture layer (SML) containing local soil, ferrous metal, charcoal and sawdust...
April 15, 2024: Journal of Hazardous Materials
https://read.qxmd.com/read/38626495/submicron-aerosol-pollution-in-greater-cairo-egypt-a-new-type-of-urban-haze
#30
JOURNAL ARTICLE
Aliki Christodoulou, Spyros Bezantakos, Efstratios Bourtsoukidis, Iasonas Stavroulas, Michael Pikridas, Konstantina Oikonomou, Minas Iakovides, Salwa K Hassan, Mohamed Boraiy, Mostafa El-Nazer, Ali Wheida, Magdy Abdelwahab, Roland Sarda-Estève, Martin Rigler, Giorgos Biskos, Charbel Afif, Agnes Borbon, Mihalis Vrekoussis, Nikos Mihalopoulos, Stéphane Sauvage, Jean Sciare
Greater Cairo, the largest megacity of the Middle East North Africa (MENA) region, is currently suffering from major aerosol pollution, posing a significant threat to public health. However, the main sources of pollution remain insufficiently characterized due to limited atmospheric observations. To bridge this knowledge gap, we conducted a continuous 2-month field study during the winter of 2019-2020 at an urban background site, documenting for the first time the chemical and physical properties of submicron (PM1 ) aerosols...
March 27, 2024: Environment International
https://read.qxmd.com/read/38626436/differential-susceptibility-of-cells-infected-with-defective-and-intact-hiv-proviruses-to-killing-by-obatoclax-and-other-small-molecules
#31
JOURNAL ARTICLE
Gayatri Nikhila Kadiyala, Sushama Telwatte, Adam Wedrychowski, Julie Janssens, Sun Jin Kim, Peggy Kim, Steven Deeks, Joseph K Wong, Steven A Yukl
OBJECTIVES: Some drugs that augment cell-intrinsic defenses or modulate cell death/survival pathways have been reported to selectively kill cells infected with HIV or SIV, but comparative studies are lacking. We hypothesized that these drugs may differ in their ability to kill cells infected with intact and defective proviruses. DESIGN: To investigate this hypothesis, drugs were tested ex vivo on Peripheral Blood Mononuclear Cells (PBMC) from nine ART-suppressed individuals...
April 16, 2024: AIDS
https://read.qxmd.com/read/38626244/genetic-drift-and-purifying-selection-shape-within-host-influenza-a-virus-populations-during-natural-swine-infections
#32
JOURNAL ARTICLE
David VanInsberghe, Dillon S McBride, Juliana DaSilva, Thomas J Stark, Max S Y Lau, Samuel S Shepard, John R Barnes, Andrew S Bowman, Anice C Lowen, Katia Koelle
Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these patterns remain poorly characterized in non-human hosts. Elucidating these dynamics is important to better understand IAV biology and the evolutionary processes that govern spillover into humans. Here, we sampled an IAV outbreak in pigs during a week-long county fair to characterize viral diversity and evolution in this important reservoir host. Nasal wipes were collected on a daily basis from all pigs present at the fair, yielding up to 421 samples per day...
April 16, 2024: PLoS Pathogens
https://read.qxmd.com/read/38623498/predominance-of-the-blastocystis-subtype-st5-among-free-living-sympatric-rodents-within-pig-farms-in-china-suggests-a-novel-transmission-route-from-farms
#33
JOURNAL ARTICLE
Fa Shan, Fang Wang, Shengke Chang, Nanhao Wang, Yufeng Liu, Xi Chen, Guanghui Zhao, Longxian Zhang
Blastocystis is a parasitic protist that can infect humans and various domestic and wild animals. However, there is limited research on the prevalence of this parasite among rodents, particularly those living in pig farm settings. Therefore, to investigate the occurrence, molecular characterization, and zoonotic potential of Blastocystis among rodents within pig farm environments, we conducted an investigation of 227 rodents and shrews from 34 pig farms located in Henan, Shaanxi, and Shanxi provinces of China using nested PCR of the SSU rRNA gene of Blastocystis ...
June 2024: One Health
https://read.qxmd.com/read/38622998/high-risk-escherichia-coli-clones-that-cause-neonatal-meningitis-and-association-with-recrudescent-infection
#34
JOURNAL ARTICLE
Nguyen Thi Khanh Nhu, Minh-Duy Phan, Steven J Hancock, Kate M Peters, Laura Alvarez-Fraga, Brian M Forde, Stacey B Andersen, Thyl Miliya, Patrick N A Harris, Scott A Beatson, Sanmarie Schlebusch, Haakon Bergh, Paul Turner, Annelie Brauner, Benita Westerlund-Wikström, Adam D Irwin, Mark A Schembri
Neonatal meningitis is a devastating disease associated with high mortality and neurological sequelae. Escherichia coli is the second most common cause of neonatal meningitis in full-term infants (herein NMEC) and the most common cause of meningitis in preterm neonates. Here, we investigated the genomic relatedness of a collection of 58 NMEC isolates spanning 1974-2020 and isolated from seven different geographic regions. We show NMEC are comprised of diverse sequence types (STs), with ST95 (34.5%) and ST1193 (15...
April 16, 2024: ELife
https://read.qxmd.com/read/38622686/deciphering-the-virome-of-chunkung-cnidium-officinale-showing-dwarfism-like-symptoms-via-a-high-throughput-sequencing-analysis
#35
JOURNAL ARTICLE
Mesele Tilahun Belete, Se Eun Kim, Workitu Firmosa Gudeta, Davaajargal Igori, Jeong A Kwon, Su-Heon Lee, Jae Sun Moon
BACKGROUND: Viruses have notable effects on agroecosystems, wherein they can adversely affect plant health and cause problems (e.g., increased biosecurity risks and economic losses). However, our knowledge of their diversity and interactions with specific host plants in ecosystems remains limited. To enhance our understanding of the roles that viruses play in agroecosystems, comprehensive analyses of the viromes of a wide range of plants are essential. High-throughput sequencing (HTS) techniques are useful for conducting impartial and unbiased investigations of plant viromes, ultimately forming a basis for generating further biological and ecological insights...
April 15, 2024: Virology Journal
https://read.qxmd.com/read/38622279/complexity-calibrated-benchmarks-for-machine-learning-reveal-when-prediction-algorithms-succeed-and-mislead
#36
JOURNAL ARTICLE
Sarah E Marzen, Paul M Riechers, James P Crutchfield
Recurrent neural networks are used to forecast time series in finance, climate, language, and from many other domains. Reservoir computers are a particularly easily trainable form of recurrent neural network. Recently, a "next-generation" reservoir computer was introduced in which the memory trace involves only a finite number of previous symbols. We explore the inherent limitations of finite-past memory traces in this intriguing proposal. A lower bound from Fano's inequality shows that, on highly non-Markovian processes generated by large probabilistic state machines, next-generation reservoir computers with reasonably long memory traces have an error probability that is at least <mml:math xmlns:mml="https://www...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38622220/research-on-the-slip-deformation-characteristics-and-improvement-measures-of-concrete-faced-rockfill-dams-on-dam-foundations-with-large-dip-angles
#37
JOURNAL ARTICLE
Jun Gao, Xiaoke Han, Wenchao Han, Faning Dang, Jie Ren, Haibin Xue, Jianyin Fang
The pumped storage power station (PSPS) is an important measure to achieve the strategic goal of "dual carbon". As one of the preferred types for the upper reservoir dams of PSPSs, the concrete-faced rockfill dam (CFRD) often has a dam foundation on a steep transverse slop and is prone to produce slip deformation along the slope, resulting in poor anti-sliding stability of the dam slope. It is dangerous for the operation safety of PSPSs. Therefore, the slip deformation of CFRDs on dam foundations with large dip angles is investigated...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38622178/impact-of-time-history-terms-on-reservoir-dynamics-and-prediction-accuracy-in-echo-state-networks
#38
JOURNAL ARTICLE
Yudai Ebato, Sou Nobukawa, Yusuke Sakemi, Haruhiko Nishimura, Takashi Kanamaru, Nina Sviridova, Kazuyuki Aihara
The echo state network (ESN) is an excellent machine learning model for processing time-series data. This model, utilising the response of a recurrent neural network, called a reservoir, to input signals, achieves high training efficiency. Introducing time-history terms into the neuron model of the reservoir is known to improve the time-series prediction performance of ESN, yet the reasons for this improvement have not been quantitatively explained in terms of reservoir dynamics characteristics. Therefore, we hypothesised that the performance enhancement brought about by time-history terms could be explained by delay capacity, a recently proposed metric for assessing the memory performance of reservoirs...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38621316/spread-of-antibiotic-resistance-genes-in-drinking-water-reservoirs-insights-from-a-deep-metagenomic-study-using-a-curated-database
#39
JOURNAL ARTICLE
Sai Wang, Wenhan Nie, Qing Gu, Xie Wang, Danping Yang, Hongyu Li, Peihong Wang, Weixue Liao, Jin Huang, Quan Yuan, Shengli Zhou, Iftikhar Ahmad, Kiga Kotaro, Gongyou Chen, Bo Zhu
The exploration of antibiotic resistance genes (ARGs) in drinking water reservoirs is an emerging field. Using a curated database, we enhanced the ARG detection and conducted a comprehensive analysis using 2.2 Tb of deep metagenomic sequencing data to determine the distribution of ARGs across 16 drinking water reservoirs and associated environments. Our findings reveal a greater diversity of ARGs in sediments than in water, underscoring the importance of extensive background surveys. Crucial ARG carriers-specifically Acinetobacter, Pseudomonas, and Mycobacterium were identified in drinking water reservoirs...
April 4, 2024: Water Research
https://read.qxmd.com/read/38621298/electronegative-phosphorus-integrated-co-2-active-sites-for-enhanced-electrocatalytic-nitrogen-reduction
#40
JOURNAL ARTICLE
Yuanyuan Xiong, Jingxian Li, Xiaoxuan Wang, Xinyue Chi, Shuyuan Li, Yanfei Sun, Zheng Tang, Zishan Hou, Jiangzhou Xie, Zhiyu Yang, Yi-Ming Yan
In the quest for proficient electrocatalysts for ammonia's electrocatalytic nitrogen reduction, cobalt oxides, endowed with a rich d-electron reservoir, have emerged as frontrunners. Despite the previously evidenced prowess of CoO in this realm, its ammonia yield witnesses a pronounced decline as the reaction unfolds, a phenomenon linked to the electron attrition from its Co2+ active sites during electrocatalytic nitrogen reduction reaction (ENRR). To counteract this vulnerability, we harnessed electron-laden phosphorus (P) elements as dopants, aiming to recalibrate the electronic equilibrium of the pivotal Co active site, thereby bolstering both its catalytic performance and stability...
April 15, 2024: Inorganic Chemistry
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