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Orthopaedics Oncology

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https://www.readbyqxmd.com/read/28196946/individualised-risk-assessment-for-local-recurrence-and-distant-metastases-in-a-retrospective-transatlantic-cohort-of-687-patients-with-high-grade-soft-tissue-sarcomas-of-the-extremities-a-multistate-model
#1
Julie J Willeumier, Anja J Rueten-Budde, Lee M Jeys, Minna Laitinen, Rob Pollock, Will Aston, P D Sander Dijkstra, Peter C Ferguson, Anthony M Griffin, Jay S Wunder, Marta Fiocco, Michiel A J van de Sande
OBJECTIVES: This study investigates the effect of surgical margins and radiotherapy, in the presence of individual baseline characteristics, on survival in a large population of high-grade soft tissue sarcoma of the extremities using a multistate model. DESIGN: A retrospective multicentre cohort study. SETTING: 4 tertiary referral centres for orthopaedic oncology. PARTICIPANTS: 687 patients with primary, non-disseminated, high-grade sarcoma only, receiving surgical treatment with curative intent between 2000 and 2010 were included...
February 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28183325/percutaneous-internal-fixation-with-y-strut%C3%A2-device-to-prevent-both-osteoporotic-and-pathological-hip-fractures-a-prospective-pilot-study
#2
François H Cornelis, Lambros Tselikas, Thibault Carteret, Bruno Lapuyade, Thierry De Baere, Jean Charles Le Huec, Frédéric Deschamps
BACKGROUND: We studied Y-STRUT® (Hyprevention, France), a new percutaneous internal fixation device, in combination with bone cementoplasty to prevent hip fracture. METHODS: Between February 2013 and February 2015, a total of 16 femoral necks in 4 osteoporotic and 12 oncologic patients have been considered for prophylactic consolidation in this prospective multicentre pilot study involving 4 different hospitals. These consolidations were performed percutaneously under fluoroscopic guidance using Y-STRUT®, a dedicated internal fixation device...
February 9, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28165797/strategies-of-enhancing-bone-regenerate-formation-in-distraction-osteogenesis
#3
Mohammad Mesfer Alzahrani, Emad Anam, Saad M AlQahtani, Asim M Makhdom, Reggie C Hamdy
Distraction osteogenesis (DO) is a commonly used technique in multiple orthopaedic specialties, including trauma, oncology and pediatrics. This technique aims to produce new bone formation in the distraction gap in a controlled manner. The issue with this technique has been the high risk of complications, one of which is poor regenerate formation during the distraction process. Although several factors (including patient and operative factors) and techniques (including surgical, mechanical and pharmacological) have been described to ensure successful regenerate formation during the process of DO, these factors are sometimes difficult to control clinically...
February 6, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28157079/treatment-outcomes-and-quality-of-life-after-the-implantation-of-modular-prostheses-of-the-proximal-femur-in-patients-with-cancer-metastases
#4
Grzegorz Guzik
BACKGROUND: Surgical treatment of pathological fractures of the proximal femur with intramedullary rods produces good short-term outcomes, but after some time the fixation often becomes unstable in patients with a good prognosis and a repeat surgery is required. Modular prostheses allow for better long-term outcomes. MATERIAL AND METHODS: A total of 64 surgical resection procedures for metastatic tumours of the proximal femur combined with the implantation of modular prostheses were performed at the Oncological Orthopaedics Department in Brzozów in 2010-2014...
May 5, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28155838/periprosthetic-metastatic-lesion-in-stem-region-after-tha-case-study
#5
Janusz Płomiński, Artur Pepłoński, Mateusz Jeśkiewicz
The paper describes a periprosthetic metastatic lesion in the stem region which developed 4 years after cementless total hip arthroplasty in a 64-year-old female patient. The patient underwent primary THA due to osteoarthritis in 2010. In June 2014, she presented with increasing hip pain. Diagnostic imaging revealed a periprosthetic osteolytic lesion in the stem region. The patient was referred to the Orthopaedic Department for further evaluation with a suspicion of pyogenic osteomyelitis. An open surgical biopsy was performed...
November 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28138720/the-dual-mobility-cup-in-muscular-skeletal-oncology-rationale-and-indications
#6
Carmine Zoccali, Dario Attala, Alessandra Scotto di Uccio, Barbara Rossi, Gennaro Scotto, Roberto Biagini
PURPOSE: Because of the improvement of medical therapy and the corresponding increase in life expectancy, orthopaedic surgeons are obliged to perform more wide resections rather than intramedullary stabilization nailing for patients affected by tumours of the hip compared to the past. Wide resection often causes joint instability, so prosthetic reconstruction presents a higher risk of dislocation than in primary osteoarthritis cases. The aim of the present paper is to classify the indications for the dual mobility cup (DMC) hip prosthesis based on the anatomic structures involved in the disease and to analyse the rationale to reduce the risk of dislocation...
January 31, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28094611/-always-go-with-your-instincts
#7
(no author information available yet)
After qualifying as a registered nurse and sick children's nurse in the 1990s, Tracey Budding worked in variety of specialties, including orthopaedics, oncology and hospice care for adults and children, before specialising in neonatal care. She has been a modern matron on the neonatal unit at Birmingham Women's Hospital NHS Foundation Trust for 15 years. Ms Budding received the RCN Award of Merit for outstanding contribution and service to RCN members.
January 4, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28048837/mo-de-202-01-image-guided-focused-ultrasound-surgery-and-therapy
#8
K Farahani
At least three major trends in surgical intervention have emerged over the last decade: a move toward more minimally invasive (or non-invasive) approach to the surgical target; the development of high-precision treatment delivery techniques; and the increasing role of multi-modality intraoperative imaging in support of such procedures. This symposium includes invited presentations on recent advances in each of these areas and the emerging role for medical physics research in the development and translation of high-precision interventional techniques...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048186/mo-de-202-02-advances-in-image-registration-and-reconstruction-for-image-guided-neurosurgery
#9
J Siewerdsen
At least three major trends in surgical intervention have emerged over the last decade: a move toward more minimally invasive (or non-invasive) approach to the surgical target; the development of high-precision treatment delivery techniques; and the increasing role of multi-modality intraoperative imaging in support of such procedures. This symposium includes invited presentations on recent advances in each of these areas and the emerging role for medical physics research in the development and translation of high-precision interventional techniques...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047534/mo-de-202-03-image-guided-surgery-and-interventions-in-the-advanced-multimodality-image-guided-operating-amigo-suite
#10
T Kapur
At least three major trends in surgical intervention have emerged over the last decade: a move toward more minimally invasive (or non-invasive) approach to the surgical target; the development of high-precision treatment delivery techniques; and the increasing role of multi-modality intraoperative imaging in support of such procedures. This symposium includes invited presentations on recent advances in each of these areas and the emerging role for medical physics research in the development and translation of high-precision interventional techniques...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046879/mo-de-202-04-multimodality-image-guided-surgery-and-intervention-for-the-rest-of-us
#11
R Shekhar
At least three major trends in surgical intervention have emerged over the last decade: a move toward more minimally invasive (or non-invasive) approach to the surgical target; the development of high-precision treatment delivery techniques; and the increasing role of multi-modality intraoperative imaging in support of such procedures. This symposium includes invited presentations on recent advances in each of these areas and the emerging role for medical physics research in the development and translation of high-precision interventional techniques...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046773/mo-de-202-00-image-guided-interventions-advances-in-intraoperative-imaging-guidance-and-an-emerging-role-for-medical-physics-in-surgery
#12
Jeffrey Siewerdsen
At least three major trends in surgical intervention have emerged over the last decade: a move toward more minimally invasive (or non-invasive) approach to the surgical target; the development of high-precision treatment delivery techniques; and the increasing role of multi-modality intraoperative imaging in support of such procedures. This symposium includes invited presentations on recent advances in each of these areas and the emerging role for medical physics research in the development and translation of high-precision interventional techniques...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040091/reconstruction-of-patellar-tendon-following-implantation-of-proximal-tibia-megaprosthesis-for-the-treatment-of-post-traumatic-septic-bone-defects
#13
Giorgio M Calori, Emilio Luigi Mazza, Luca Vaienti, Simone Mazzola, Alessandra Colombo, Luca Gala, Massimiliano Colombo
INTRODUCTION: Latest advances made in joint replacement implants allows reconstruction of entire limbs. These special prostheses or megaprostheses were originally designed for the treatment of severe oncological bone loss. Nowadays, however, the indications and applications of these devices are expanding to other orthopaedic and trauma clinical conditions. Since 2008 we have implanted 152 megaprostheses in non-oncological conditions: 87 were implanted for post-traumatic failures aseptic/septic (represented by complex non-unions and critical size bone defects); 26 total femur, 52 distal femur and 9 proximal tibia...
December 2016: Injury
https://www.readbyqxmd.com/read/28008380/strategies-for-obtaining-bone-biopsy-specimens-from-breast-cancer-patients-past-experience-and-future-directions
#14
Mohammed F K Ibrahim, John Hilton, Christina Addison, Susan Robertson, Joel Werier, Sasha Mazzarello, Lisa Vandermeer, Carmel Jacobs, Mark Clemons
BACKGROUND: Cancer and its treatment can have multiple effects on the bone. Despite the widespread use of in vivo and in vitro models, it is still necessary to understand these effects in humans. Obtaining human bone biopsies is technically challenging and in this article we review the experiences from the Ottawa Bone Oncology Program. METHODS: A series of bone biopsy studies in breast cancer patients with and without bone metastasis have been performed. We reviewed the results of these studies and present them in a descriptive manner...
November 2016: Journal of Bone Oncology
https://www.readbyqxmd.com/read/27927830/lesson-of-the-month-2-oncology-obstetrics-and-orthopaedics-an-unusual-partnership
#15
Claire Fuller, Catherine Bale, Jill Bishop, Paul Cool
Breast cancer diagnosed during pregnancy is a relatively uncommon event. This challenging situation presents clinicians with difficult decisions, often requiring a multidisciplinary approach at a time of heightened anxiety for the patient and their family. This paper describes the case of a young woman with metastatic breast cancer diagnosed in early pregnancy, and outlines how this complex clinical situation was managed.
December 2016: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/27856381/what-questionnaires-to-use-when-measuring-quality-of-life-in-sacral-tumor-patients-the-updated-sacral-tumor-survey
#16
Olivier D R van Wulfften Palthe, Stein J Janssen, Jay S Wunder, Peter C Ferguson, Guo Wei, Peter S Rose, Micheal J Yaszemski, Franklin H Sim, Patrick J Boland, John H Healey, Francis J Hornicek, Joseph H Schwab
BACKGROUND CONTEXT: Patient-reported outcomes are becoming increasingly important when investigating results of patient and disease management. In sacral tumor, the symptoms of patients can vary substantially; therefore, no single questionnaire can adequately account for the full spectrum of symptoms and disability. PURPOSE: The purpose of this study is to analyze redundancy within the current sacral tumor survey and make a recommendation for an updated version based on the results and patient and expert opinions...
November 14, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27811349/prevalence-and-characteristics-of-surgical-site-infections-caused-by-gram-negative-rod-shaped-bacteria-from-the-family-enterobacteriacae-and-gram-positive-cocci-from-the-genus-staphylococcus-in-patients-who-underwent-surgical-procedures-on-selected-surgical
#17
Małgorzata Tomaszewska-Kowalska, Krzysztof Kołomecki, Maria Wieloch-Torzecka
: Surgical site infections on surgical wards are the most common cause of postoperative complications. Prevalence of surgical site infections depends on the surgical specialization. Analysis of the causes of surgical site infections allows to conclude that microorganisms from the patient's own microbiota - Gram-negative rod-shaped bacteria from the family Enterobacteriacae and from the patient's skin microbiota - Gram-positive cocci - Staphylococcus are the most common agents inducing surgical site infections...
October 1, 2016: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/27752988/what-factors-are-associated-with-quality-of-life-pain-interference-anxiety-and-depression-in-patients-with-metastatic-bone-disease
#18
Q M J van der Vliet, N R Paulino Pereira, S J Janssen, F J Hornicek, M L Ferrone, J A M Bramer, C N van Dijk, J H Schwab
BACKGROUND: It would be helpful for the decision-making process of patients with metastatic bone disease to understand which patients are at risk for worse quality of life (QOL), pain, anxiety, and depression. Normative data, and where these stand compared with general population scores, can be useful to compare and interpret results of similar patients or patient groups, but to our knowledge, there are no such robust data. QUESTIONS/PURPOSES: We wished (1) to assess what factors are independently associated with QOL, pain interference, anxiety, and depression in patients with metastatic bone disease, and (2) to compare these outcomes with general US population values...
February 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27733194/are-performance-indicators-used-for-hospital-quality-management-a-qualitative-interview-study-amongst-health-professionals-and-quality-managers-in-the-netherlands
#19
Daan Botje, Guus Ten Asbroek, Thomas Plochg, Helen Anema, Dionne S Kringos, Claudia Fischer, Cordula Wagner, Niek S Klazinga
BACKGROUND: Hospitals are under increasing pressure to share indicator-based performance information. These indicators can also serve as a means to promote quality improvement and boost hospital performance. Our aim was to explore hospitals' use of performance indicators for internal quality management activities. METHODS: We conducted a qualitative interview study among 72 health professionals and quality managers in 14 acute care hospitals in The Netherlands. Concentrating on orthopaedic and oncology departments, our goal was to gain insight into data collection and use of performance indicators for two conditions: knee and hip replacement surgery and breast cancer surgery...
October 13, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27681061/denis-burkitt-a-legacy-of-global-health
#20
Daniel Esau
When first described in 1958, Burkitt lymphoma was considered by many to be an African curiosity. However, over the next few decades, over 10,000 publications on Burkitt lymphoma would influence many facets of oncology research including immunology, molecular genetics, chemotherapy, and viral oncology. At the time of discovery, its distribution in equatorial Africa was unique; it was where a child was born and lived, and not what race they were, that conveyed the greatest incidence risk. Its association with Epstein-Barr virus brought attention to the possibility that oncogenesis may be influenced by viruses...
September 28, 2016: Journal of Medical Biography
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