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Orthopaedics Oncology

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https://www.readbyqxmd.com/read/29112544/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-day-surgery-and-fast-track-surgery
#1
Linas Venclauskas, Juan V Llau, Jean-Yves Jenny, Per Kjaersgaard-Andersen, Øivind Jans
: In recent years, day surgery and fast-track surgery have experienced a continuous increase in volume. Many procedures are now performed on an outpatient protocol, including general, orthopaedic, oncological, reconstructive or vascular surgery. The management of these patients is safe, but the incidence of venous thromboembolism in this population remains unknown. Several risk factors can be identified and stratified derived from studies of inpatient surgical management (e.g. Caprini score). Recommendations for thromboprophylaxis should be tailored from the assessment of both personal and procedure-related risk factors, although with a lack of evidence for application in outpatient management...
November 6, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29031873/does-specialty-matter-a-survey-on-176-italian-neurosurgeons-and-orthopaedic-spine-surgeons-confirms-similar-competency-for-common-spinal-conditions-and-supports-multidisciplinary-teams-in-comprehensive-and-complex-spinal-care
#2
Matteo Pejrona, Gabriele Ristori, Jorge Hugo Villafañe, Fabrizio Ernesto Pregliasco, Pedro Berjano
BACKGROUND CONTEXT: Spine surgery is a multi-faceted sub-speciality requiring a breadth of knowledge and skill from different branches of medicine for the treatment of pathologies varying from degenerative to deformity, oncological, and trauma. PURPOSE: The aim of the study was to investigate the self-perceived competency of spine surgeons in relation to different types of spinal procedures. STUDY DESIGN/SETTING: Survey study. METHODS: We conducted a survey on 176 surgeons (Orthopaedic surgeons and Neurosurgeons)...
October 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29025611/carbon-fiber-reinforced-intramedullary-nailing-in-musculoskeletal-tumor-surgery-a-national-multicentric-experience-of-the-italian-orthopaedic-society-siot-bone-metastasis-study-group
#3
Andrea Piccioli, Raimondo Piana, Michele Lisanti, Alberto Di Martino, Barbara Rossi, Francesco Camnasio, Marco Gatti, Pietro Maniscalco, Franco Gherlinzoni, Maria Silvia Spinelli, Davide Maria Donati, Roberto Biagini, Rodolfo Capanna, Vincenzo Denaro
INTRODUCTION: Carbon fiber reinforced (CFR) implants have been proposed for the treatment of fractures or impending fractures of the long bones in the oncology patient. Aim of this study is to present the largest cohort of oncology patients operated by CFR nailing by the Italian Orthopaedic Society (SIOT) Bone Metastasis Study Group. METHODS: 53 adult oncology patients were operated on with a CFR-PEEK nail. All the data from adjuvants therapies were collected. Bone callus formation, response to radiotherapy, relapse or progression of the osteolysis were recorded...
October 2017: Injury
https://www.readbyqxmd.com/read/28934820/-bone-metastases-pathophysiology-diagnostic-testing-and-therapy-part-1
#4
Sebastian Koob, Michael Kehrer, Andreas Strauss, Viktor Janzen, Dieter Christian Wirtz, Jan Schmolders
In Germany and other European countries, cancer is the second most common cause of death after cardiovascular disease. Although 5-year survival rates for several types of cancer have significantly improved over the last 30 years, metastasis to the bone almost always leads to incurable disease. Aside from the rare primary bone tumours, the treatment of bone metastases now accounts for a major part of tumour orthopaedic workload and requires close interdisciplinary coordination between specialists in oncology, radiology and the discipline of the primary tumour entity...
September 21, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28929405/corr-insights-%C3%A2-moving-forward-through-consensus-a-modified-delphi-approach-to-determine-the-top-research-priorities-in-orthopaedic-oncology
#5
Timothy A Damron
No abstract text is available yet for this article.
December 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28919087/outcomes-of-restrictive-versus-liberal-transfusion-strategies-in-older-adults-from-nine-randomised-controlled-trials-a-systematic-review-and-meta-analysis
#6
Geoff I Simon, Alison Craswell, Ogilvie Thom, Yoke Lin Fung
BACKGROUND: Guidelines for patient blood management recommend restrictive transfusion practice for most adult patients. These guidelines are supported by evidence from randomised controlled trials (RCTs); however, one of the patient groups not explicitly examined in these studies is the geriatric population. We examined RCTs relevant to transfusion outcomes in older patients. Our aim was to determine whether special guidelines are warranted for geriatric patients, recognising the different pathophysiological characteristics of this group...
October 2017: Lancet Haematology
https://www.readbyqxmd.com/read/28890435/pain-control-in-thoracic-oncology
#7
Christine Peeters-Asdourian, Gilbert Massard, Paragi H Rana, Paul Van Houtte, Andrew P White, Bogdan Grigoriu, Dominique Lossignol, Mohammed Almalki, Jean Alexiou, Jean-Luc Engelholm, Jean-Paul Sculier
This review of pain management in lung cancer is based on the presentation of four cases of thoracic oncology patients with pain at various stages of their disease. The approach will be multidisciplinary, involving a thoracic oncologist, radiologist, thoracic and orthopaedic spine surgeon, radiation therapist, pain medicine specialist, and palliative care specialist. This multispecialty approach to the management of different painful presentations in thoracic oncology will demonstrate the complexity of each case and the improved patient outcomes which result from the involvement of different disciplines working in concert...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28856514/moving-forward-through-consensus-a-modified-delphi-approach-to-determine-the-top-research-priorities-in-orthopaedic-oncology
#8
Patricia Jacqueline Schneider, Nathan Evaniew, Paula McKay, Michelle Ghert
BACKGROUND: Several challenges presently impede the conduct of prospective clinical studies in orthopaedic oncology, including limited financial resources to support their associated costs and inadequate patient volume at most single institutions. This study was conducted to prioritize research questions within the field so that the Musculoskeletal Tumor Society (MSTS), and other relevant professional societies, can direct the limited human and fiscal resources available to address the priorities that the stakeholders involved believe will have the most meaningful impact on orthopaedic oncology patient care...
December 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28853588/malignant-bone-tumours-of-the-foot
#9
P Yang, S Evans, N Bali, A Ramasamy, R Evans, J Stevenson, L Jeys, R Grimer
Introduction Malignant osseous foot tumours are uncommon. Their oncological outcomes have been poorly documented in the literature so far. The aim of this study was to establish the incidence and to evaluate the oncological outcomes of such patients. Methods Our large orthopaedic oncology database was used to review 70 malignant osseous foot tumour patients. Results The age at diagnosis of malignant osseous foot tumours demonstrated a bimodal distribution peaking in the second and eighth decades of life. Overall, 55 primary malignant bone tumours of the foot (79%) were identified...
September 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28840090/cold-atmospheric-plasma-in-orthopaedic-and-urologic-tumor-therapy
#10
REVIEW
Denis Gümbel, Georg Daeschlein, Axel Ekkernkamp, Axel Kramer, Matthias B Stope
Cold atmospheric plasma (CAP) is a highly reactive ionized physical state thereby provoking divers biological effects. In medical applications, CAP treatment promotes wound healing, provokes immunostimulation, and is antiseptically active. Moreover, CAP interacts with antiproliferative mechanisms suggesting CAP treatment as a promising anticancer strategy. Here we review the current state of science concerning the so far investigated CAP effects on different cancer entities in orthopaedic and urologic oncology...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/28790787/allogenic-bone-grafts-in-post-traumatic-juxta-articular-defects-need-for-allogenic-bone-banking
#11
REVIEW
Anil Kumar Mishra, Rohit Vikas, H S Agrawal
Allogenic bone banking provide both structural and granular bone grafts for various orthopaedic, spinal, oncological and dental surgeries. However allogenic bones, presently, are not readily available. This article discusses the clinical applications of the allogenic grafts, the screening criteria and procedure for maintenance of such a bone banking facility. This article demonstrates the effective role of allogenic bone in a case of post-traumatic bone loss situation and discusses the growing need and present situation of bone banking in our country...
July 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28696671/simultaneous-delivery-of-multiple-antibacterial-agents-from-additively-manufactured-porous-biomaterials-to-fully-eradicate-planktonic-and-adherent-staphylococcus-aureus
#12
S Bakhshandeh, Z Gorgin Karaji, K Lietaert, A C Fluit, C H E Boel, H C Vogely, T Vermonden, W E Hennink, H Weinans, A A Zadpoor, S Amin Yavari
Implant-associated infections are notoriously difficult to treat and may even result in amputation and death. The first few days after surgery are the most critical time to prevent those infections, preferably through full eradication of the micro-organisms entering the body perioperatively. That is particularly important for patients with a compromised immune system such as orthopedic oncology patients, as they are at higher risk for infection and complications. Full eradication of bacteria is, especially in a biofilm, extremely challenging due to the toxicity barrier that prevents delivery of high doses of antibacterial agents...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28629828/factors-associated-with-the-decision-of-operative-procedure-for-proximal-femoral-bone-metastasis-questionnaire-survey-to-institutions-participating-the-bone-and-soft-tissue-tumor-study-group-of-the-japan-clinical-oncology-group
#13
Nobuhito Araki, Hirokazu Chuman, Tomoya Matsunobu, Kazuhiro Tanaka, Hirohisa Katagiri, Toshiyuki Kunisada, Toru Hiruma, Hiroaki Hiraga, Hideo Morioka, Hiroshi Hatano, Kunihiro Asanuma, Yoshihiro Nishida, Koji Hiraoka, Takeshi Okamoto, Satoshi Abe, Munenori Watanuki, Takeshi Morii, Hideshi Sugiura, Yukihiro Yoshida, Takatoshi Ohno, Hidetatsu Outani, Koichiro Yokoyama, Shoji Shimose, Haruhiko Fukuda, Yukihide Iwamoto
BACKGROUND: Pathological fracture of the proximal femur is a main cause of cancer patients losing their ability to walk. Although both osteosynthetic devices (predominantly intramedullary nails) and prosthetic replacement have been widely performed for treatment, controversies exist regarding which procedure should be used for the various conditions. In order to decide the eligibility criteria of a planned randomized prospective study about the treatment of pathological fractures of the proximal femur, we assessed the factors affecting the selection of operative procedures using questionnaires sent to the members of the Bone and Soft Tissue Tumor Study Group (BSTTSG) of the Japan Clinical Oncology Group (JCOG)...
September 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28580663/autologous-blood-salvage-in-the-era-of-patient-blood-management
#14
REVIEW
R A Sikorski, N A Rizkalla, W W Yang, S M Frank
Almost 150 years after the first autologous blood transfusion was reported, intraoperative blood salvage has become an important method of blood conservation. The primary goal of autologous transfusion is to reduce or avoid allogeneic red blood cell transfusion and the associated risks and costs. Autologous salvaged blood does not result in immunological challenge and its consequences, provides a higher quality red blood cell that has not been subjected to the adverse effects of blood storage, and can be more cost-effective than allogeneic blood when used for carefully selected surgical patients...
June 5, 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/28515060/barriers-and-facilitators-experienced-in-collaborative-prospective-research-in-orthopaedic-oncology-a-qualitative-study
#15
J S Rendon, M Swinton, N Bernthal, M Boffano, T Damron, N Evaniew, P Ferguson, M Galli Serra, W Hettwer, P McKay, B Miller, L Nystrom, W Parizzia, P Schneider, A Spiguel, R Vélez, K Weiss, J P Zumárraga, M Ghert
OBJECTIVES: As tumours of bone and soft tissue are rare, multicentre prospective collaboration is essential for meaningful research and evidence-based advances in patient care. The aim of this study was to identify barriers and facilitators encountered in large-scale collaborative research by orthopaedic oncological surgeons involved or interested in prospective multicentre collaboration. METHODS: All surgeons who were involved, or had expressed an interest, in the ongoing Prophylactic Antibiotic Regimens in Tumour Surgery (PARITY) trial were invited to participate in a focus group to discuss their experiences with collaborative research in this area...
May 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28508770/romuald-w%C3%A4-g%C3%A5-owski-1876-1935-orthopaedic-surgeon-forgotten-pioneer-of-limb-saving-tumour-surgery
#16
Marek Durakiewicz, Mirosław Jabłoński, Aneta Zarębska
On May 16, 1914, The Lancet Journal published a paper by Romuald Węgłowski, a Polish-born professor of Moscow University, entitled "Malignant tumours of bones: a new method in conservative operative treatment." The idea of biological resection presented in the paper consisted in thermocoagulation of the apparently cancerous part of a bone with a jet of steam. According to the author, dead bone rid of live malignant cells reconstructed itself quickly, which helped to preserve the functionality of the organ without considerable limitations...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28508766/comparison-of-quality-of-life-of-patients-after-hip-disarticulation-and-those-after-stump-lengthening-with-modular-prosthesis
#17
Grzegorz Guzik
BACKGROUND: Disarticulation has been used less and less often in the treatment of musculoskeletal neoplasms; however, in some cases it allows the patient to achieve good oncological and functional outcomes. The aim of this paper is to present the possibilities, surgical technique and treatment outcomes of patients after hip disarticulation and stump lengthening with a modular prosthesis. MATERIAL AND METHODS: Three classic hip disarticulation surgeries and 2 hip disarticulation procedures with stump lengthening with a modular prosthesis were performed at the Department of Oncological Orthopaedics in Brzozów in 2013 and 2014...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28508765/a-comparison-of-outcomes-of-treatment-with-resection-prosthesis-of-the-hip-in-revision-and-oncological-surgery
#18
Paweł Kamiński, Jakub Szmyd, Jarosław Ambroży, Jerzy Mirosław Jaworski, Bogusław Frańczuk
INTRODUCTION: The introduction of resection prostheses paved the way for the development of limb-sparing surgery in patients with primary or metastatic bone tumours. After some time, the developing possibilities of treatment of extensive bone defects allowed for the use of resection prostheses as an emergency procedure in patients undergoing revision surgery due to hip implant loosening. The aim of this paper is to compare treatment outcomes in patients receiving the Modular Universal Tumour and Revision System (MUTARS) resection prosthesis during arthroplasty performed for different indications: treatment of a tumour metastasis and revision surgery in cases of implant loosening...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28508764/current-incidence-of-different-morphological-types-of-malignant-metastases-to-the-spine-based-on-magnetic-resonance-imaging
#19
Grzegorz Guzik
BACKGROUND: Malignant tumours particularly often metastasise to the spine, causing considerable pain and limiting the patient's physical function. Standard therapy consists in surgical treatment with adjuvant radiotherapy. The qualification for surgery is a multifaceted process and detailed analysis of the morphology of the metastasis is a key factor. Numerous types of classification of metastatic lesions exist, among which the Tomita system, based on MRI findings, appears to be the most practical...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28502707/surgical-innovation-in-sarcoma-surgery
#20
L Jeys, G Morris, S Evans, J Stevenson, M Parry, J Gregory
The field of orthopaedic oncology relies on innovative techniques to resect and reconstruct a bone or soft tissue tumour. This article reviews some of the most recent and important innovations in the field, including biological and implant reconstructions, together with computer-assisted surgery. It also looks at innovations in other fields of oncology to assess the impact and change that has been required by surgeons; topics including surgical margins, preoperative radiotherapy and future advances are discussed...
May 11, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
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