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https://www.readbyqxmd.com/read/29333827/rectus-sheath-hematoma-in-a-macrosomie-neonate-following-difficult-delivery-case-report
#1
Suzan Gunduz, Semra Kara, Ayşe Aktas, Abdulkadir Eren, Vedat Bakan
Macrosomia is a risk factor for birth injuries and is associated with neonatal morbidity and mortality. Cephalohematoma and clavicular fracture are the most frequent birth injuries. Intraabdominal injuries are uncommon birth injuries. Rectus sheath hematoma (RSH) is an accumulation of blood in the sheath of rectus abdominis muscle. It is associated with trauma, operations and anticoagulant therapy, especially in adults and elders. We present a macrosomic male neonate with difficult vaginal delivery, who had in the physical examination periumblical ecchymose of 1x1 cm and a parietal cephalohametoma of 1x1 cm...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29326162/structural-basis-for-p-ppgpp-synthesis-by-the-staphylococcus-aureus-small-alarmone-synthetase-relp
#2
Melek Cemre Manav, Jelena Beljantseva, Martin Saxtorph Bojer, Tanel Tenson, Hanne Ingmer, Vasili Hauryliuk, Ditlev Egeskov Brodersen
The stringent response is a global reprogramming of bacterial physiology that renders cells more tolerant to antibiotics and induces virulence gene expression in pathogens in response to stress. This process is driven by accumulation of the intracellular alarmone guanosine-5'-di(tri)phosphate-3'-diphosphate ([p]ppGpp), which is produced by enzymes of the RelA SpoT homologue (RSH) family. The Gram-positive Firmicute pathogen, Staphylococcus aureus, encodes three RSH enzymes: a multi-domain RSH (Rel) that senses amino acid starvation on the ribosome and two small alarmone synthetase (SAS) enzymes, RelQ (SAS1) and RelP (SAS2)...
January 11, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29300776/prevalence-of-relative-systemic-hypertension-in-adults-with-sickle-cell-disease-in-ghana
#3
Amma Benneh-Akwasi Kuma, Amma Twumwa Owusu-Ansah, Mary Akua Ampomah, Fredericka Sey, Edeghonghon Olayemi, Mehdi Nouraie, Solomon Fiifi Ofori-Acquah
Individuals with sickle cell disease particularly with the homozygous (SS) genotype historically have relatively low blood pressure. Nonetheless, they develop vasculopathy-associated organ dysfunction and the risk of organ dysfunction increases at blood pressures that are normal in the general population. This phenomenon is termed relative systemic hypertension (RSH) with a systolic blood pressure range of 120-139 mmHg, and diastolic blood pressure range of 70-89 mmHg. The significance of RSH lies in its association with renal insufficiency, pulmonary hypertension, stroke and propensity to progress to systemic hypertension...
2018: PloS One
https://www.readbyqxmd.com/read/29300449/alkoxybenzothiadiazole-based-fullerene-and-nonfullerene-polymer-solar-cells-with-high-shunt-resistance-for-indoor-photovoltaic-applications
#4
Song Yi Park, Yuxiang Li, Jaewon Kim, Tack Ho Lee, Bright Walker, Han Young Woo, Jin Young Kim
We synthesized three semi-crystalline polymers (PTTBTBO, PDTBTBO, and P2FDTBTBO) by modulating the intra- and intermolecular noncovalent coulombic interactions, and investigated their photovoltaic characteristics under various light intensities. Low series (Rs) and high shunt (Rsh) resistances are essential prerequisites for good device properties under standard illumination (100 mW cm-2). Considering these factors, among three polymers PDTBTBO polymer solar cells (PSCs) exhibited the most desirable characteristics, with peak power conversion efficiencies (PCE) of 7...
January 4, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29222649/effect-of-oral-zinc-supplementation-on-the-thiol-oxido-reductive-index-and-thiol-related-enzymes-in-seminal-plasma-and-spermatozoa-of-iraqi-asthenospermic-patients
#5
Abdul Razzaq S Alsalman, Lamia A Almashhedy, Mahmoud Hussein Hadwan
A thiol group plays an essential role in sperm metabolism and the antioxidative defense state. Zinc is the second most abundant element in the human body, following iron. The present study was conducted to study the effect of zinc supplementation on the characteristics of semen along with thiol and thiol-related enzymes in semen of asthenospermic patients. Semen samples were obtained from 60 fertile and 60 asthenospermic men, from couples who had consulted the infertility clinic of Babil Hospital (Hillah city, Iraq)...
December 8, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29216811/phrase-lengths-and-the-perceived-informativeness-of-prosodic-cues-in-turkish
#6
Nazik Dinçtopal Deniz, Janet Dean Fodor
It is known from previous studies that in many cases (though not all) the prosodic properties of a spoken utterance reflect aspects of its syntactic structure, and also that in many cases (though not all) listeners can benefit from these prosodic cues. A novel contribution to this literature is the Rational Speaker Hypothesis (RSH), proposed by Clifton, Carlson and Frazier. The RSH maintains that listeners are sensitive to possible reasons for why a speaker might introduce a prosodic break: "listeners treat a prosodic boundary as more informative about the syntax when it flanks short constituents than when it flanks longer constituents," because in the latter case the speaker might have been motivated solely by consideration of optimal phrase lengths...
December 2017: Language and Speech
https://www.readbyqxmd.com/read/29181148/abdominal-compartment-syndrome-due-to-spontaneous-rectus-sheath-hematoma-with-extension-into-the-retroperitoneal-space
#7
Aimal Khan, Jay Strain, Pak Shan Leung, Mark J Kaplan
Rectus sheath hematoma (RSH) is an increasingly common clinical condition in our hospitals due to the increasing use of anticoagulant therapies for various purposes among our patients. Treatment of spontaneous RSH is generally conservative. For continued bleeding, interventional radiologic identification and subsequent embolization is an effective option. Surgery usually involves significant morbidity and is considered a technique of last resort. In this case report, we describe the case of middle aged female who developed abdominal compartment syndrome (ACS) from a large RSH that had extended into the retroperitoneum...
November 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29115650/spontaneous-rectus-sheath-hematoma-in-cardiac-in-patients-a-single-center-experience
#8
Ebubekir Gündeş, Durmuş Ali Çetin, Ulaş Aday, Hüseyin Çiyiltepe, Kamuran Cumhur Değer, Orhan Uzun, Aziz Serkan Senger, Erdal Polat, Mustafa Duman
BACKGROUND: This study presents the relationship between mortality and spontaneous rectus sheath hematoma (RSH) in inpatients receiving anticoagulant and antiaggregant treatment for cardiac pathology at cardiology and cardiovascular surgery clinics. METHODS: Within the scope of our study, the cases of 27 patients who were diagnosed with spontaneous RSH between January 2010 and December 2015 at Kartal Kosuyolu High Speciality Training and Research Hospital were retrospectively evaluated...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29114271/organized-chronic-subdural-hematomas-treated-by-large-craniotomy-with-extended-membranectomy-as-the-initial-treatment
#9
Mustafa Balevi
Objective: The aim of this retrospective study is to evaluate the efficacy and incidence of complications of craniotomy and membranectomy in elderly patients for the treatment of organized chronic subdural hematoma (OCSH). Materials and Methods: We retrospectively reviewed a series of 28 consecutive patients suffering from OCSH, diagnosed by magnetic resonance imaging (MRI) or computer tomography (CT) to establish the degree of organization and determine the intrahematomal architecture including inner membrane ossification...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29112440/chemical-biology-of-h2s-signaling-through-persulfidation
#10
Milos R Filipovic, Jasmina Zivanovic, Beatriz Alvarez, Ruma Banerjee
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for understanding the physiological and pharmacological effects of H2S. Due to the inherent instability of persulfides, their chemistry is understudied. In this review, we discuss the biologically relevant chemistry of H2S and the enzymatic routes for its production and oxidation. We cover the chemical biology of persulfides and the chemical probes for detecting them...
November 7, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/29102872/shoulder-balance-in-lenke-type-2-adolescent-idiopathic-scoliosis-should-we-fuse-to-the-second-thoracic-vertebra
#11
Huiliang Yang, Gi Hye Im, Bowen Hu, Lei Wang, Chunguang Zhou, Limin Liu, Yueming Song
OBJECTIVES: There are many different systems recommending upper instrumented vertebra (UIV) for Lenke type 2 adolescent idiopathic scoliosis (AIS), several of which suggest that all Lenke type 2 AIS patients should be fused to the second thoracic vertebra (T2). However, all previously proposed UIV selecting systems do not accurately predict postoperative shoulder balance. We investigated whether fusing to T2 could prevent postoperative shoulder imbalance and identified circumstances under which to fuse up to T2...
October 31, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29032393/acute-effects-of-repeated-cycling-sprints-in-hypoxia-induced-by-voluntary-hypoventilation
#12
Xavier Woorons, Patrick Mucci, Julien Aucouturier, Agathe Anthierens, Grégoire P Millet
PURPOSE: This study aimed to investigate the acute responses to repeated-sprint exercise (RSE) in hypoxia induced by voluntary hypoventilation at low lung volume (VHL). METHODS: Nine well-trained subjects performed two sets of eight 6-s sprints on a cycle ergometer followed by 24 s of inactive recovery. RSE was randomly carried out either with normal breathing (RSN) or with VHL (RSH-VHL). Peak (PPO) and mean power output (MPO) of each sprint were measured. Arterial oxygen saturation, heart rate (HR), gas exchange and muscle concentrations of oxy-([O2Hb]) and deoxyhaemoglobin/myoglobin ([HHb]) were continuously recorded throughout exercise...
December 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28984392/spin-state-energetics-of-fe-complexes-from-an-optimally-tuned-range-separated-hybrid-functional
#13
Georgia Prokopiou, Leeor Kronik
We assess the performance of the optimally-tuned range separated hybrid (OT-RSH) functional approach in predicting the ground-state electronic configuration and spin-state energetics of complexes that can potentially exhibit multiple spin configurations. To that end, we investigate eight iron complexes: Four spin-crossover complexes, for which reference data from other approximate density functionals are available, and four smaller complexes, for which reference ab initio data are available. We show that the spin-state energetics are mostly governed by the percentage of short-range exact exchange and are only weakly influenced by the choice of the range-separation parameter...
October 6, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28973902/drk-mediated-signaling-to-rho-kinase-is-required-for-anesthesia-resistant-memory-in-drosophila
#14
Vasileia Kotoula, Anastasios Moressis, Ourania Semelidou, Efthimios M C Skoulakis
Anesthesia-resistant memory (ARM) was described decades ago, but the mechanisms that underlie this protein synthesis-independent form of consolidated memory in Drosophila remain poorly understood. Whether the several signaling molecules, receptors, and synaptic proteins currently implicated in ARM operate in one or more pathways and how they function in the process remain unclear. We present evidence that Drk, the Drosophila ortholog of the adaptor protein Grb2, is essential for ARM within adult mushroom body neurons...
October 10, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28948393/within-and-beyond-the-stringent-response-rsh-and-p-ppgpp-in-plants
#15
REVIEW
Justyna Boniecka, Justyna Prusińska, Grażyna B Dąbrowska, Anna Goc
Plant RSH proteins are able to synthetize and/or hydrolyze unusual nucleotides called (p)ppGpp or alarmones. These molecules regulate nuclear and chloroplast transcription, chloroplast translation and plant development and stress response. Homologs of bacterial RelA/SpoT proteins, designated RSH, and products of their activity, (p)ppGpp-guanosine tetra-and pentaphosphates, have been found in algae and higher plants. (p)ppGpp were first identified in bacteria as the effectors of the stringent response, a mechanism that orchestrates pleiotropic adaptations to nutritional deprivation and various stress conditions...
November 2017: Planta
https://www.readbyqxmd.com/read/28937532/prevalence-risk-factors-and-characteristics-of-the-adding-on-phenomenon-in-idiopathic-scoliosis-after-correction-surgery-a-systematic-review-and-meta-analysis
#16
Mingyuan Yang, Yuechao Zhao, Xin Yin, Ziqiang Chen, Changwei Yang, Li Li, Ming Li
STUDY DESIGN: A systematic review and meta-analysis OBJECTIVE.: To discuss the prevalence, risk factors and characteristics of the 'adding-on' phenomenon in idiopathic scoliosis (IS). SUMMARY OF BACKGROUND DATA: There are controversies on the prevalence and risk factors of the 'adding-on' phenomenon. In addition, there is no comprehensive study to describe the characteristics of 'adding-on' in IS patients. METHODS: We performed a systematic online search using PubMed, EMBASE, Web of Science, the Cochrane Library and China WeiPu Library to identify eligible studies...
September 20, 2017: Spine
https://www.readbyqxmd.com/read/28926245/hno-is-produced-by-the-reaction-of-no-with-thiols
#17
Sebastian A Suarez, Martina Muñoz, Lucia Alvarez, Mateus F Venâncio, Willian R Rocha, Damian E Bikiel, Marcelo A Marti, Fabio Doctorovich
Azanone (nitroxyl, HNO) is a highly reactive compound whose biological role is still a matter of debate. One possible route for its formation is NO reduction by biological reductants. These reactions have been historically discarded due to the negative redox potential for the NO,H+/HNO couple. However, the NO to HNO conversion mediated by vitamins C, E, and aromatic alcohols has been recently shown to be feasible from a chemical standpoint. Based on these precedents, we decided to study the reaction of NO with thiols as potential sources of HNO...
October 4, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28889339/incidence-and-risk-factors-for-postoperative-shoulder-imbalance-in-scoliosis-a-systematic-review-and-meta-analysis
#18
ShengFei Zhang, Liang Zhang, XinMin Feng, HuiLin Yang
PURPOSE: This is the first systematic review and meta-analysis to detect the incidence and risk factors for postoperative shoulder imbalance (PSI) in scoliosis. METHODS: A systematic online search was conducted to identify eligible studies. ES, OR and WMD with 95% CI were used to assess the incidence and risk factors associated with PSI. RESULTS: Twenty-six studies were recruited. The pooled incidence of PSI was 25% (95% CI 20-31%). The incidence in Lenke 1 AIS, Lenke 2 AIS, Lenke 5 AIS and mixed AIS was 20% (9-31%), 26% (15-37%), 31% (17-45%) and 27% (19-35%), respectively...
September 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28873301/optimal-tuning-of-range-separated-hybrids-for-solvated-molecules-with-time-dependent-density-functional-theory
#19
Martina Rubešová, Eva Muchová, Petr Slavíček
The applicability range of density functional theory (DFT) can be improved with no additional parametrization by imposing some exact conditions. Enforcing equality between the orbital energy of the highest occupied Kohn-Sham orbital and ionization energy, determined from the total energy difference between neutral and ionized states (ΔKS), leads to the concept of optimally tuned range-separated hybrid functionals. Here, we present an alternative tuning scheme for range-separated hybrid functionals based on enforcing the equality between the ΔKS ionization energy and the ionization energy calculated by means of the time-dependent DFT using the concept of ionization as an excitation to the distant center (OT-IEDC scheme)...
September 25, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28871248/identification-and-functional-characterization-of-small-alarmone-synthetases-in-corynebacterium-glutamicum
#20
Matthias Ruwe, Jörn Kalinowski, Marcus Persicke
The hyperphosphorylated guanosine derivatives ppGpp and pppGpp represent global regulators of the bacterial stress response, as they act as central elements of the stringent response system. Although it was assumed that both, (p)ppGpp synthesis and hydrolysis, are catalyzed by one bifunctional RSH-protein in the actinobacterial model organism Corynebacterium glutamicum ATCC 13032, two putative short alarmone synthetases (SASs) were identified by bioinformatic analyses. The predicted sequences of both enzymes, designated as RelP(*)Cg and RelSCg, exhibit high similarities to the conserved (p)ppGpp synthetase catalytic domain...
2017: Frontiers in Microbiology
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