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Lactated ringer's metabolic acidosis

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https://www.readbyqxmd.com/read/28985713/patients-with-glycogen-storage-diseases-undergoing-anesthesia-a-case-series
#1
Carmelina Gurrieri, Juraj Sprung, Toby N Weingarten, Mary E Warner
BACKGROUND: Glycogen storage diseases are rare genetic disorders of glycogen synthesis, degradation, or metabolism regulation. When these patients are subjected to anesthesia, perioperative complications can develop, including hypoglycemia, rhabdomyolysis, myoglobinuria, acute renal failure, and postoperative fatigue. The objective of this study was to describe the perioperative course of a cohort of patients with glycogen storage diseases. METHODS: This is a retrospective review of patients with glycogen storage diseases undergoing anesthetic care at our institution from January 1, 1990, through June 30, 2015 to assess perioperative management and outcomes...
October 6, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28933805/perioperative-administration-of-buffered-versus-non-buffered-crystalloid-intravenous-fluid-to-improve-outcomes-following-adult-surgical-procedures
#2
REVIEW
Sohail Bampoe, Peter M Odor, Ahilanandan Dushianthan, Elliott Bennett-Guerrero, Suzie Cro, Tong J Gan, Michael Pw Grocott, Michael Fm James, Michael G Mythen, Catherine Mn O'Malley, Anthony M Roche, Kathy Rowan, Edward Burdett
BACKGROUND: Perioperative fluid strategies influence clinical outcomes following major surgery. Many intravenous fluid preparations are based on simple solutions, such as normal saline, that feature an electrolyte composition that differs from that of physiological plasma. Buffered fluids have a theoretical advantage of containing a substrate that acts to maintain the body's acid-base status - typically a bicarbonate or a bicarbonate precursor such as maleate, gluconate, lactate, or acetate...
September 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28682955/ringer-s-lactate-versus-normal-saline-in-urgent-cesarean-delivery-in-a-resource-limited-setting-a-pragmatic-clinical-trial
#3
Emmanuel Timarwa Ayebale, Arthur Kwizera, Cephas Mijumbi, Samuel Kizito, Anthony Michael Roche
BACKGROUND: Crystalloids are used routinely for perioperative fluid management in cesarean delivery. Few studies have determined the crystalloid of choice in obstetric anesthesia. We compared the effects of Ringer's lactate (RL) versus 0.9% normal saline (NS) on maternal and neonatal blood pH and 24-hour postoperative morbidity in urgent cesarean delivery in a low-resource setting. Our hypothesis was that RL would result in 30% less acidosis than NS. METHODS: This was a pragmatic prospective double-blind randomized controlled trial in the Mulago National Referral Hospital Labor Ward Theater from September 2011 to May 2012...
August 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28078858/use-of-lactated-ringer%C3%A2-s-solution-does-not-eliminate-the-risk-of-strong-ion-difference-related-metabolic-acidosis-following-on-pump-cardiac-surgery
#4
LETTER
T Jovaisa, V Vicka, G Linkaitė, J Guseinovaitė, D Ringaitienė, I Norkienė
There is a growing interest in the effects of plasma sodium levels on postoperative outcomes. A trend of using balanced crystalloid solutions is based on the extensive data on chloride and the strong ion difference-related acidosis. However, effects of sodium are often overlooked in this context. The aim of the study was to establish the effects of the routine use of Lactated Ringer’s Solution (RL) on postoperative changes in sodium concentrations and whether these changes result in metabolic acidosis. We performed database analysis of 358 consecutive elective on-pump cardiac surgery cases in a tertiary referral university hospital...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28077541/the-role-of-bicarbonate-precursors-in-balanced-fluids-during-haemorrhagic-shock-with-and-without-compromised-liver-function
#5
B Ergin, A Kapucu, P Guerci, C Ince
BACKGROUND: Lactate, acetate, and gluconate are anions used in balanced resuscitation fluids, of which lactate and acetate are considered bicarbonate precursors. This study investigated the role of the liver in the ability of balanced and unbalanced solutions to correct acid-base alterations and renal haemodynamics and microvascular oxygenation in a rat model of resuscitated haemorrhagic shock. METHODS: Ringer's lactate, Ringer's acetate, PlasmaLyte, or normal saline were administered following haemorrhagic shock in the presence or absence of a 70% partial liver resection...
October 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/27871516/pediatric-patients-on-ketogenic-diet-undergoing-general-anesthesia-a-medical-record-review
#6
Elif Soysal, Heike Gries, Carter Wray
STUDY OBJECTIVE: To identify guidelines for anesthesia management and determine whether general anesthesia is safe for pediatric patients on ketogenic diet (KD). DESIGN: Retrospective medical record review. SETTING: Postoperative recovery area. PATIENTS: All pediatric patients who underwent general anesthesia while on KD between 2009 and 2014 were reviewed. We identified 24 patients who underwent a total of 33 procedures...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27848268/use-of-intravenous-fluids-solutions-a-narrative-review
#7
REVIEW
N El Gkotmi, C Kosmeri, T D Filippatos, M S Elisaf
OBJECTIVE: Intravenous fluids are broadly categorized into colloids and crystalloids. The aim of this review is to present under a clinical point of view the characteristics of intravenous fluids that make them more or less appropriate either for maintaining hydration when enteral intake is contraindicated or for treating hypovolemia. METHODS: We considered randomized trials and meta-analyses as well as narrative reviews evaluating the effects of colloids or crystalloids in patients with hypovolemia or as maintenance fluids published in the PubMed and Cochrane databases...
March 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/27289617/use-of-ringer-s-lactate-solution-does-not-eliminate-the-risk-of-strong-ion-difference-related-metabolic-acidosis-following-on-pump-cardiac-surgery
#8
I Norkiene, G Linkaite, J Guseinovaite, V Vicka, D Ringaitiene, T Jovaisa
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27083135/dextrose-containing-intraoperative-fluid-in-neonates-a-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Priyankar K Datta, Dilip K Pawar, Dalim K Baidya, Souvik Maitra, Ajisha Aravindan, Maddur Srinivas, Ramakrishnan Lakshmy, Nandita Gupta, Minu Bajpai, Veereshwar Bhatnagar, Sandeep Agarwala
BACKGROUND: Glucose requirement in neonates during surgery and the impact of glucose supplementation on neonatal metabolism remain unclear. AIM: This study was designed to identify an appropriate perioperative fluid regimen in neonates which maintains carbohydrate and lipid homeostasis. METHODS: Forty-five neonates undergoing primary repair of a trachea-esophageal fistula were randomly allocated into three groups. During surgery, the neonates received either 1% dextrose in Ringer lactate (RL) (group D1) at 10 ml·kg(-1) ·h(-1) , or 2% dextrose in RL (group D2) at 10 ml·kg(-1) ·h(-1) , or 10% dextrose in N/5 saline at 4 ml·kg(-1) ·h(-1) and replacement fluid with 6 ml·kg(-1) ·h(-1) of RL (group D4)...
June 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/26266925/effects-of-atrial-natriuretic-peptide-on-inter-organ-crosstalk-among-the-kidney-lung-and-heart-in-a-rat-model-of-renal-ischemia-reperfusion-injury
#10
Chieko Mitaka, May Khin Hnin Si, Miniwan Tulafu, Qi Yu, Tokujiro Uchida, Shinya Abe, Masanobu Kitagawa, Satoshi Ikeda, Yoshinobu Eishi, Makoto Tomita
BACKGROUND: Renal ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury and a frequent occurrence in critically ill patients. Renal IRI releases proinflammatory cytokines within the kidney that induce crosstalk between the kidney and other organ systems. Atrial natriuretic peptide (ANP) has anti-inflammatory as well as natriuretic effects and serves important functions as a regulator of blood pressure, fluid homeostasis, and inflammation. The objective of the present study was to elucidate whether ANP post-treatment attenuates kidney-lung-heart crosstalk in a rat model of renal IRI...
December 2014: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/26108552/the-great-fluid-debate-saline-or-so-called-balanced-salt-solutions
#11
REVIEW
Maristella Santi, Sebastiano A G Lava, Pietro Camozzi, Olivier Giannini, Gregorio P Milani, Giacomo D Simonetti, Emilio F Fossali, Mario G Bianchetti, Pietro B Faré
BACKGROUND: Intravenous fluids are commonly prescribed in childhood. 0.9 % saline is the most-used fluid in pediatrics as resuscitation or maintenance solution. Experimental studies and observations in adults suggest that 0.9 % saline is a poor candidate for fluid resuscitation. Although anesthesiologists, intensive care specialists, perioperative physicians and nephrologists have been the most active in this debate, this issue deserves some physiopathological considerations also among pediatricians...
June 25, 2015: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/26106600/comparison-of-malated-ringer-s-with-two-other-balanced-crystalloid-solutions-in-resuscitation-of-both-severe-and-moderate-hemorrhagic-shock-in-rats
#12
Judith Keitel, Bjoern Hussmann, Sven Lendemans, Herbert de Groot, Ricarda Rohrig
In preclinical treatment of polytraumatized patients crystalloids are preferentially used. To avoid metabolic acidosis, metabolizable anions like lactate or acetate are used to replace chloride in these solutions. We here studied the effects of malated Ringer's in resuscitation of both shock severities in comparison to lactated and acetated Ringer's. Male Wistar rats underwent severe (mean arterial blood pressure (MAP) of 25-30 mmHg) or moderate (MAP 40-45 mmHg) hemorrhagic shock. Adjacent to the shock period animals were resuscitated with acetated (AR), lactated (LR), or malated Ringer's (MR) and observed for 150 min...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26091132/blood-biochemical-changes-in-pigs-after-infusion-with-acetate-buffered-or-lactate-buffered-crystalloid-solutions
#13
Claudia Keibl, Wolfgang Sipos, Martin Ponschab, Christoph J Schlimp
Perioperative fluid therapy is an important component of many medical procedures with animals. Buffered crystalloid solutions avoid inducing metabolic acidosis, but lactated solutions can elevate blood lactate concentrations and acetated solutions have not been thoroughly investigated using large animals. Here, the authors compare blood biochemical parameters in 20 juvenile pigs after perioperative fluid administration of an acetate-buffered solution (Elo-Mel isoton, EMI) or a lactate-buffered solution (lactated Ringer's solution, LRS)...
July 2015: Lab Animal
https://www.readbyqxmd.com/read/26047259/protective-effects-of-polyethylene-oxide-on-the-vascular-and-organ-function-of-rats-with-severe-hemorrhagic-shock
#14
Qiang Li, Tao Huang, Zhen Dong
This study examined the effects of polyethylene oxide (PEO) on the survival rate, hemodynamics, blood gas indexes, lactic acid levels, microcirculation, and inflammatory cytokine levels in rats subjected to severe hemorrhagic shock. The shocked rats were resuscitated with either Ringer's lactate solution or 20 ppm of PEO in Ringer's lactate solution for 1 h. It was found that infusion of PEO effectively improved the survival, metabolic acidosis, oxygen delivery, hyperlactacidemia, tissue perfusion, and inflammatory responses of rats subjected to hemorrhagic shock...
August 2015: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/25943188/anesthesia-and-organic-aciduria-is-the-use-of-lactated-ringer-s-solution-absolutely-contraindicated
#15
Katerina Ruzkova, Toby N Weingarten, Kelly J Larson, Robert J Friedhoff, Dimitar K Gavrilov, Juraj Sprung
BACKGROUND: Organic acidurias (OAs) are rare inborn errors of metabolism that can present with various neurologic manifestations, propensity for acute metabolic decompensation with anion-gap metabolic acidosis, developmental delay, poor feeding, and failure to thrive. OBJECTIVE: In this case series, we outline the anesthetic management and perioperative outcomes of OA patients. METHODS: We reviewed demographic characteristics, comorbidities, and perioperative course of patients with four different OAs who underwent anesthetic care at our institution between January 1, 2000, and December 31, 2013...
August 2015: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/25812486/correction-of-hypovolemia-with-crystalloid-fluids-individualizing-infusion-therapy
#16
REVIEW
George Liamis, Theodosios D Filippatos, Moses S Elisaf
Many situations in clinical practice involving patients with hypovolemia or acutely ill patients usually require the administration of intravenous fluids. Current evidence shows that the use of crystalloids should be considered, since most colloids and human albumin are usually associated with increased adverse effects and high cost, respectively. Among crystalloids, the use of normal saline is implicated with the development of hyperchloremic metabolic acidosis and renal vasoconstriction. These observations have led many authors to propose balanced solutions, mainly Lactated Ringer's, as the infusate of choice...
May 2015: Postgraduate Medicine
https://www.readbyqxmd.com/read/25433283/hypothermic-initially-oxygen-free-controlled-limb-reperfusion-for-acute-limb-ischemia
#17
Christian A P Schmidt, Zoran Rancic, Mario L Lachat, Dieter O Mayer, Frank J Veith, Markus J Wilhelm
BACKGROUND: Controlled limb reperfusion has been shown to prevent the deleterious effects of ischemia-reperfusion (IR) syndrome following revascularization of acute limb ischemia (ALI). To reduce the production of cell-toxic oxygen-free radicals, we have established a new initially oxygen-free, hypothermic, heparin-coated perfusion and hemofiltration system and report on our first results. METHODS: In a retrospective single-center study, controlled limb reperfusion was applied in 36 patients (64...
April 2015: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/24736393/isotonic-crystalloid-solutions-a-structured-review-of-the-literature
#18
REVIEW
D Orbegozo Cortés, A Rayo Bonor, J L Vincent
BACKGROUND: Several different crystalloid solutions are available for i.v. fluid administration but there is little information about their specific advantages and disadvantages. METHODS: We performed a systematic search of MEDLINE, EMBASE, and CENTRAL up until May 17, 2012, selecting all prospective human studies that directly compared any near-isotonic crystalloids and reported any outcome. RESULTS: From the 5060 articles retrieved in the search, only 28 met the selection criteria...
June 2014: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/24404459/evaluation-of-the-efficacy-of-simplified-fencl-stewart-equation-in-analyzing-the-changes-in-acid-base-status-following-resuscitation-with-two-different-fluids
#19
S Moied Ahmed, P Maheshwari, S Agarwal, Abu Nadeem, L Singh
BACKGROUND: Metabolic acid-base disorders in critically ill patients may not be identified by base excess (BE) approach. Anion gap method can detect approximately 1/3 hidden "gap acidosis". In such conditions, when adjusted for hypoalbuminemia, Fencl-Stewart's approach can reliably detect the hidden abnormal anions. AIM: Evaluate the efficacy of simplified Fencl-Stewart equation in identifying the changes in acid-base status of sepsis patients following resuscitation with two different fluids...
July 2013: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/24330733/comparisons-of-normal-saline-and-lactated-ringer-s-resuscitation-on-hemodynamics-metabolic-responses-and-coagulation-in-pigs-after-severe-hemorrhagic-shock
#20
COMPARATIVE STUDY
Wenjun Z Martini, Douglas S Cortez, Michael A Dubick
BACKGROUND: Ongoing improvements in trauma care now recommend earlier use of blood products as part of damage control resuscitation, but generally these products are not available at far forward battlefield locations. For the military, questions continue to arise regarding efficacy of normal saline (NS) vs. lactated Ringer's (LR). Thus, this study compared the effects of LR and NS after severe hemorrhage in pigs. METHODS: 20 anesthetized pigs were randomized into control (n = 6), LR (n = 7), and NS (n = 7) groups...
December 11, 2013: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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