Xiaoxing Cui, Zhen Li, Yanbo Teng, Karoline K Barkjohn, Christina L Norris, Lin Fang, Gina N Daniel, Linchen He, Lili Lin, Qian Wang, Drew B Day, Xiaojian Zhou, Jianguo Hong, Jicheng Gong, Feng Li, Jinhan Mo, Yinping Zhang, James J Schauer, Marilyn S Black, Michael H Bergin, Junfeng Zhang
Importance: Fine particles (particulate matter 2.5 μm [PM2.5]), a ubiquitous air pollutant, can deposit in the small airways that play a vital role in asthma. It appears to be unknown whether the use of a PM2.5 filtration device can improve small airway physiology and respiratory inflammation in children with asthma. Objective: To discover what pathophysiological changes in the small airways are associated with using a PM2.5-removing device in the bedrooms of children with asthma...
April 6, 2020: JAMA Pediatrics