Rahul Gujarathi, Manisha Rakesh Lakhanpal, Nikhila Chelikam, Divesh Manjani, Simmy Lahori, Sai Anusha Akella, Prashanth Gumpu Shivashankar, Francis Vino Dominic Savio, Abdirazak Ibrahim Ali, Navyatha Annareddy, Aryak Singh, Lokesh Manjani, Prasanthi Vanga, Avinash Adiga
Multiple myeloma (MM), constituting 10% of hematological malignancies, poses significant morbidity and mortality, especially with skeletal involvement. Bisphosphonate use in MM may lead to severe hypocalcemia due to vitamin D deficiency (VDD), exacerbating bone marrow plasma cell burden. We aimed to assess VDD prevalence and its impact on outcomes in MM patients. A retrospective cross-sectional analysis (2008-2018) of nationwide inpatient data identified adult MM hospitalizations with VDD using ICD-10-CM codes...
April 17, 2024: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research