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https://www.readbyqxmd.com/read/28335526/oral-cyanocobalamin-is-effective-in-the-treatment-of-vitamin-b12-deficiency-in-crohn-s-disease
#1
Fernando Gomollón, Carla J Gargallo, Jose Fernando Muñoz, Raquel Vicente, Alberto Lue, Alberto Mir, Marta García-Alvarado, Marta Gracia, Santiago García-López
Cobalamin deficiency is common in patients with Crohn's disease (CD). Intramuscular cobalamin continues to be the standard therapy for the deficiency and maintenance treatment in these patients, although oral route has been demonstrated to be effective in other pathologies with impaired absorption. Our aims were to evaluate the efficacy of oral therapy in the treatment of cobalamin deficiency and in long-term maintenance in patients with Crohn's disease. We performed a multicenter retrospective cohort study that included 94 patients with Crohn's disease and cobalamin deficiency...
March 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28335514/the-association-between-vitamin-d-deficiency-and-diabetic-retinopathy-in-type-2-diabetes-a-meta-analysis-of-observational-studies
#2
Bang-An Luo, Fan Gao, Lu-Lu Qin
Emerging evidence from in vivo and in vitro studies have shown that vitamin D may play an important role in the development of diabetic retinopathy (DR), but individually published studies showed inconclusive results. The aim of this study was to quantitatively summarize the association between vitamin D and the risk of diabetic retinopathy. We conducted a systematic literature search of Pubmed, Medline, and EMBASE updated in September 2016 with the following keywords: "vitamin D" or "cholecalciferol" or "25-hydroxyvitamin D" or "25(OH)D" in combination with "diabetic retinopathy" or "DR"...
March 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28335483/land-use-for-edible-protein-of-animal-origin-a-review
#3
REVIEW
Gerhard Flachowsky, Ulrich Meyer, Karl-Heinz Südekum
The present period is characterized by a growing world population and a higher demand for more and better quality food, as well as other products for an improved standard of living. In the future, there will be increasingly strong competition for arable land and non-renewable resources such as fossil carbon-sources, water, and some minerals, as well as between food, feed, fuel, fiber, flowers, and fun (6 F's). Proteins of animal origin like milk, meat, fish, eggs and, probably, insects are very valuable sources of essential amino acids, minerals and vitamins, but their production consumes some non-renewable resources including arable land and causes considerable emissions...
March 18, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28335477/association-between-circulating-vitamin-d-level-and-urolithiasis-a-systematic-review-and-meta-analysis
#4
REVIEW
Henglong Hu, Jiaqiao Zhang, Yuchao Lu, Zongbiao Zhang, Baolong Qin, Hongbin Gao, Yufeng Wang, Jianning Zhu, Qing Wang, Yunpeng Zhu, Yang Xun, Shaogang Wang
Many studies compared the serum/plasma 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D) and 25 hydroxyvitamin D₃ (25(OH)D) between people with and without nephrolithiasis, and their results were conflicting. After systematically searching PubMed, Web of Science, The Cochrane Library, CNKI, and the Wanfang Database, we conducted a meta-analysis. Thirty-two observational studies involving 23,228 participants were included. Meta-analysis of these studies showed that of stone formers (SFs), calcium SFs had significantly higher concentrations of 1,25(OH)₂D (weighted mean difference (WMD), 10...
March 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28335380/vitamin-e-nicotinate
#5
REVIEW
Kimbell R Duncan, Yuichiro J Suzuki
Vitamin E refers to a family of compounds that function as lipid-soluble antioxidants capable of preventing lipid peroxidation. Naturally occurring forms of vitamin E include tocopherols and tocotrienols. Vitamin E in dietary supplements and fortified foods is often an esterified form of α-tocopherol, the most common esters being acetate and succinate. The vitamin E esters are hydrolyzed and converted into free α-tocopherol prior to absorption in the intestinal tract. Because its functions are relevant to many chronic diseases, vitamin E has been extensively studied in respect to a variety of diseases as well as cosmetic applications...
March 13, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28335085/modifications-in-dietary-and-alcohol-intakes-between-before-and-after-cancer-diagnosis-results-from-the-prospective-population-based-nutrinet-sant%C3%A3-cohort
#6
Philippine Fassier, Laurent Zelek, Lucie Lécuyer, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Emmanuelle Kesse-Guyot, Julia Baudry, Serge Hercberg, Mélanie Deschasaux, Mathilde Touvier
Post-diagnosis diet and alcohol consumption may be associated with cancer prognosis, recurrence and mortality. Our aim was to investigate food, nutrient and alcohol intake variations between before and after cancer diagnosis and their determinants in a prospective cohort. Subjects (n=696) were incident cancer cases diagnosed in the NutriNet-Santé cohort between 2009 and 2016. Food, nutrient and alcohol intakes were prospectively collected using repeated non-consecutive 24-h dietary records since subjects' inclusion (i...
March 23, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28335003/identification-of-genetic-variants-affecting-vitamin-d-receptor-binding-and-associations-with-autoimmune-disease
#7
Giuseppe Gallone, Wilfried Haerty, Giulio Disanto, Sreeram V Ramagopalan, Chris P Ponting, Antonio J Berlanga-Taylor
Large numbers of statistically significant associations between sentinel SNPs and case-control status have been replicated by genome-wide association studies. Nevertheless, few underlying molecular mechanisms of complex disease are currently known. We investigated whether variation in binding of a transcription factor, the vitamin D receptor (VDR) whose activating ligand vitamin D has been proposed as a modifiable factor in multiple disorders, could explain any of these associations. VDR modifies gene expression by binding DNA as a heterodimer with the Retinoid X receptor (RXR)...
March 9, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28334845/infantile-tremor-syndrome-and-subdural-hemorrhage-in-an-infant-with-cystic-fibrosis
#8
Anirban Mandal, Mayank Priyadarshi, Kanaram Jat, Sushil Kumar Kabra
Cystic fibrosis (CF), an autosomal recessive disease with multi-system involvement, may present with bleeding in infancy owing to vitamin K malabsorption. Infantile tremor syndrome (ITS) is an obscure condition associated with vitamin B12 and other micronutrient deficiencies, described predominantly in Indian subcontinent. We describe an infant presenting with ITS and chronic subdural hemorrhage. He was subsequently diagnosed to have CF. The ITS and subdural hemorrhage is rarely reported in children with CF...
February 23, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28334792/gwas-identifies-population-specific-new-regulatory-variants-in-fut6-associated-with-plasma-b12-concentrations-in-indians
#9
Suraj S Nongmaithem, Charudatta V Joglekar, Ghattu V Krishnaveni, Sirazul A Sahariah, Meraj Ahmad, Swetha Ramachandran, Meera Gandhi, Harsha Chopra, Anand Pandit, Ramesh D Potdar, Caroline Hd Fall, Chittaranjan S Yajnik, Giriraj R Chandak
Vitamin B12 is an important cofactor in one-carbon metabolism whose dysregulation is associated with various clinical conditions. Indians have a high prevalence of B12 deficiency but little is known about the genetic determinants of circulating B12 concentrations in Indians. We performed a genome-wide association study in 1001 healthy participants in the Pune Maternal Nutrition Study (PMNS), replication studies in 3418 individuals from other Indian cohorts and by meta-analysis identified new variants, rs3760775 (p = 1...
February 27, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28334709/micronutrients-essential-fatty-acids-and-bone-health-in-phenylketonuria
#10
Serwet Demirdas, Francjan J van Spronsen, Carla E M Hollak, J Hanneke van der Lee, Peter H Bisschop, Fred M Vaz, Nienke M Ter Horst, M Estela Rubio-Gozalbo, Annet M Bosch
INTRODUCTION: In phenylketonuria (PKU), a natural protein-restricted dietary treatment prevents severe cognitive impairment. Nutrient deficiencies may occur due to strict diet. This study is aimed at evaluating the dietary intake and blood concentrations of micronutrients and essential fatty acids (FA), bone mineral density (BMD) and fracture history in patients on long-term dietary treatment. METHODS: Sixty early diagnosed Dutch patients (aged 1-39 years) were included in a multi-center cross-sectional study...
March 24, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28334220/effect-of-vitamin-d-deficiency-in-developed-countries
#11
Zaki K Hassan-Smith, Martin Hewison, Neil J Gittoes
Introduction: Vitamin D deficiency is common worldwide with adverse effects on skeletal health. In recent years, there has been great interest in non-classical actions of vitamin D. Basic research has uncovered actions in a range of non-skeletal tissues, and observational studies have identified inverse relationships with risk of a number of disease states including sarcopenia, obesity, the metabolic syndrome, cardiovascular disease, cancer and autoimmune diseases. Sources of data: PubMed, Medline and Cochrane Systematic Reviews...
March 9, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28334009/vitamin-d-status-and-the-prevalence-of-deficiency-in-lactating-women-from-eight-provinces-and-municipalities-in-china
#12
Yao Zhao, Yingjie Yu, Hong Li, Zhirong Chang, Yongjin Li, Yifan Duan, Jie Wang, Shan Jiang, Zhenyu Yang, Shi-An Yin
BACKGROUND: Vitamin D deficiency has become prevalent worldwide in recent years. However, less evidence was available for lactating women. OBJECTIVE: The purpose of the study was to understand vitamin D status and prevalence of deficiency in lactating women and associated risk factors for vitamin D deficiency from eight provinces and municipalities in China. METHODS: Lactating women within 1-10 months postpartum were recruited in 2011-2013 from eight provinces and municipalities in China...
2017: PloS One
https://www.readbyqxmd.com/read/28333864/vitamin-d-and-th17-lymphocytes
#13
Mostafa G Aly, Gerhard Opelz, Volker Daniel
No abstract text is available yet for this article.
March 22, 2017: Transplantation
https://www.readbyqxmd.com/read/28333766/dietary-inadequacies-in-hiv-infected-and-uninfected-school-aged-children-in-johannesburg-south-africa
#14
Stephanie Shiau, Acadia Webber, Renate Strehlau, Faeezah Patel, Ashraf Coovadia, Samantha Kozakowski, Susan Brodlie, Michael T Yin, Louise Kuhn, Stephen M Arpadi
OBJECTIVES: The World Health Organization (WHO) recommends that HIV-infected children increase energy intake and maintain a balanced macronutrient distribution for optimal growth and nutrition. Few studies have evaluated dietary intake of HIV-infected children in resource-limited settings. METHODS: We conducted a cross-sectional analysis of the dietary intake of 220 perinatally HIV-infected children and 220 HIV-uninfected controls ages 5-9 years in Johannesburg, South Africa...
March 22, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28333554/a-comparative-content-analysis-of-vegetarian-food-blogs-written-by-registered-dietitians-and-non-registered-dietitians
#15
Audrée-Anne Dumas, Simone Lemieux, Annie Lapointe, Marilyn Dugrenier, Sophie Desroches
This purpose of this study was to compare the nutritional content of vegetarian recipes published in food blogs written by registered dietitians (RDs) and by non-registered dietitians (non-RDs). Twelve food blogs written by RDs and 12 written by non-RDs were selected using a systematic approach. For each food blog, 2 vegetarian entrée recipes per season were selected (n = 192 recipes). Descriptive analyses were performed using Fisher's exact test. Median nutritional values per serving between RDs' and non-RDs' recipes were compared using Wilcoxon-Mann-Whitney tests...
March 23, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28333357/dietary-patterns-foods-and-nutrients-in-male-fertility-parameters-and-fecundability-a-systematic-review-of-observational-studies
#16
Albert Salas-Huetos, Mònica Bulló, Jordi Salas-Salvadó
BACKGROUND: Infertility is a global public health issue, affecting 15% of all couples of reproductive age. Male factors, including decreased semen quality, are responsible for ~25% of these cases. The dietary pattern, the components of the diet and nutrients have been studied as possible determinants of sperm function and/or fertility. OBJECTIVE AND RATIONALE: Previous systematic reviews have been made of the few heterogeneous low-quality randomized clinical trials (RCTs) conducted in small samples of participants and investigating the effect of specific nutrients and nutritional supplements on male infertility...
March 10, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28333352/reply-vitamin-d-and-ovarian-reserve-making-clinical-decisions
#17
Ian S McLennan, Michael W Pankhurst
No abstract text is available yet for this article.
March 4, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28333350/vitamin-d-and-ovarian-reserve-making-clinical-decisions
#18
Panagiotis Drakopoulos, A La Marca, Nikolaos P Polyzos
No abstract text is available yet for this article.
March 4, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28333154/maternal-neonatal-vitamin-d-deficiency-a-new-risk-factor-for-necrotizing-enterocolitis-in-preterm-infants
#19
M Cetinkaya, T Erener-Ercan, T Kalayci-Oral, A Babayiğit, B Cebeci, S Y Semerci, G Buyukkale
OBJECTIVE: The objective of the study was to investigate the possible association between maternal/neonatal 25-hydroxy vitamin D (25-OHD) levels and development of necrotizing enterocolitis (NEC). STUDY DESIGN: One hundred and forty-five preterm infants ⩽36 weeks of gestation were enrolled. 25-OHD levels were determined in maternal/neonatal blood samples that were obtained at the time of admission to the neonatal intensive care unit. RESULTS: Of the 145 enrolled patients, 26 (18%) developed NEC...
March 23, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28333132/enzyme-iia-ntr-regulates-salmonella-invasion-via-1-2-propanediol-and-propionate-catabolism
#20
Woongjae Yoo, Dajeong Kim, Hyunjin Yoon, Sangryeol Ryu
Many Proteobacteria possess a nitrogen-metabolic phosphotransferase system (PTS(Ntr)) consisting of EI(Ntr), NPr, and EIIA(Ntr) (encoded by ptsP, ptsO, and ptsN, respectively). The PTS(Ntr) plays diverse regulatory roles, but the substrate phosphorylated by EIIA(Ntr) and its primary functions have not yet been identified. To comprehensively understand the roles of PTS(Ntr) in Salmonella Typhimurium, we compared the whole transcriptomes of wild-type and a ΔptsN mutant. Genome-wide RNA sequencing revealed that 3...
March 23, 2017: Scientific Reports
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