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Contrast enhanced ultrasound

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https://www.readbyqxmd.com/read/29333116/is-there-a-role-for-contrast-enhanced-ultrasound-in-the-detection-and-biopsy-of-mri-only-visible-breast-lesions
#1
Aki Nykänen, Otso Arponen, Anna Sutela, Ritva Vanninen, Mazen Sudah
Background: This study aimed to evaluate the feasibility of contrast-enhanced ultrasound (CEUS) and CEUS-guided interventions in the diagnostics of MRI visible targeted US occult breast lesions. Patients and methods: This retrospective study examined 10 females with 10 occult, MRI only detected breast lesions between July 2014 and April 2017. Targeted second look US followed by CEUS with 2.4 ml of SonoVue® were performed for all of the lesions. After positive CEUS localization the same dose was repeated for confirmation and CEUS-guided interventions were performed...
December 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/29332247/practical-advantages-of-contrast-enhanced-ultrasound-in-abdominopelvic-radiology
#2
Praveen Ganti Ranganath, Michelle L Robbin, Susan J Back, Edward G Grant, David T Fetzer
Computed tomography (CT) and magnetic resonance imaging (MRI) are two of the workhorse modalities of abdominopelvic radiology. However, these modalities are not without patient- and technique-specific limitations that may prevent a timely and accurate diagnosis. Contrast-enhanced ultrasound (CEUS) is an effective, rapid, and cost-effective imaging modality with expanding clinical utility in the United States. In this pictorial essay, we provide a case-based discussion demonstrating the practical advantages of CEUS in evaluating a variety of pathologies in which CT or MRI was precluded or insufficient...
January 13, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29331357/differentiation-of-inflammatory-from-fibrotic-ileal-strictures-among-patients-with-crohn-s-disease-based-on-visual-analysis-feasibility-study-combining-conventional-b-mode-ultrasound-contrast-enhanced-ultrasound-and-strain-elastography
#3
Emilio Quaia, Antonio Giulio Gennari, Maria Assunta Cova, Edwin J R van Beek
The aim of this pilot study was to assess prospectively the feasibility of conventional B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) combined with real-time strain elastography (SE) in the differentiation of inflammatory from fibrotic ileal strictures among patients with Crohn's disease (CD) based on visual analysis. Twenty non-consecutive patients (15 male and 5 female; mean age ± standard deviation, 40.2 ± 10.22 y) with CD and stricture of the terminal ileal loop were scanned by conventional B-mode US and CEUS and, subsequently, by real-time SE...
January 10, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29330670/treatment-of-partial-thickness-rotator-cuff-tears-in-overhead-athletes
#4
REVIEW
Joseph N Liu, Grant H Garcia, Anirudh K Gowd, Brandon C Cabarcas, Michael D Charles, Anthony A Romeo, Nikhil N Verma
PURPOSE OF REVIEW: To review the etiology, classification, presentation, evaluation, treatment strategy, and outcomes in overhead athletes with partial thickness rotator cuff tears. RECENT FINDINGS: Despite advances in surgical repair techniques, return to play following surgical repair of partial rotator cuff tears remains modest at best. Overhead athletes may be particularly prone to rotator cuff pathology due to the supraphysiological strains within the tendon during the throwing motion, as well as mechanical stress with contact between the undersurface of the rotator cuff and the glenoid...
January 13, 2018: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/29329991/dynamic-contrast-enhanced-eus-for-quantification-of-tumor-perfusion-in-colonic-cancer-a-prospective-cohort-study
#5
Marie Louise Malmstrøm, Adrian Săftoiu, Lene B Riis, Hazem Hassan, Tobias W Klausen, Mikkel S Rahbek, Ismail Gögenur, Peter Vilmann
BACKGROUND AND AIMS: Dynamic contrast enhanced endoscopic ultrasound (CE-EUS) for quantification of perfusion in colonic tumors has not previously been reported in the literature. The aim of the study was to investigate correlations between perfusion parameters and vessel density assessed by immunohistochemical staining with antibodies toward CD31 and CD105. METHODS: We conducted a prospective clinical study. In total, 28 patients with left-sided colonic adenocarcinoma, underwent CE-EUS and left-sided hemicolectomy within 2 weeks...
January 9, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29325584/adenomatoid-tumor-of-the-testis-mimicking-malignant-testicular-cancer-on-multiparametric-ultrasound
#6
Renate Pichler, Gennadi Tulchiner, Fabian Steinkohl, Afschin Soleiman, Wolfgang Horninger, Isabel Maria Heidegger, Friedrich Aigner
BACKGROUND: Adenomatoid tumor is one of the most common histological subtypes of paratesticular cancer arising from the epididymis. In very rare cases, these tumors appear as intratesticular lesions originating in the tunica albuginea, representing a diagnostic challenge. CASE PRESENTATION: We present a case of a 51-year-old man with a small (0.9 cm) hyperechoic lesion of the left testicle mimicking testicular cancer on multiparametric ultrasound. The lesion was localized in the peripheral zone, confirming vascularization and increased stiffness on contrast-enhanced ultrasound and real-time elastography...
January 11, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29324482/enhanced-needle-visibility-by-micro-air-bubble-contrast-in-ultrasound-guided-nerve-block
#7
Yong Liu, Wei Mei
No abstract text is available yet for this article.
January 12, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29323044/magnetic-resonance-imaging-guided-focused-ultrasound-to-increase-localized-blood-spinal-cord-barrier-permeability
#8
Allison H Payne, Gregory W Hawryluk, Yoshimi Anzai, Henrik Odéen, Megan A Ostlie, Ethan C Reichert, Amanda J Stump, Satoshi Minoshima, Donna J Cross
Spinal cord injury (SCI) affects thousands of people every year in the USA, and most patients are left with some permanent paralysis. Therapeutic options are limited and only modestly affect outcome. To address this issue, we used magnetic resonance imaging-guided focused ultrasound (MRgFUS) as a non-invasive approach to increase permeability in the blood-spinal cord barrier (BSCB). We hypothesize that localized, controlled sonoporation of the BSCB by MRgFUS will aid delivery of therapeutics to the injury. Here, we report our preliminary findings for the ability of MRgFUS to increase BSCB permeability in the thoracic spinal cord of a normal rat model...
December 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29322796/pitfalls-of-contrast-enhanced-ultrasound-ceus-in-determination-of-breast-tumor-biological-dignity
#9
V Lehotska, K Rauova, L Vanovcanova
The aim of this prospective study was to identify characteristics of breast lesions on contrast enhanced ultrasound (CEUS) that can be a source of diagnostic ambiguity and cause under- or overestimation of examined breast lesions. 215 women (range 23-76 y., mean age 53.16 y) with 215 breast lesions were examined by B-mode ultrasound, followed by CEUS and core biopsy. CEUS parameters: degree of opacification, character of washout and preliminary CEUS result (suspicious, non-suspicious, uncertain) were subsequently correlated with histopathological outcomes...
2018: Neoplasma
https://www.readbyqxmd.com/read/29317035/deciphering-the-breast-density-inform-law-movement-implications-for-practice
#10
Sean D Raj, Valerie Fein-Zachary, Priscilla J Slanetz
Although dense breast tissue is a normal and routine finding on screening mammography, dense breast tissue is associated with an independent increased risk for breast cancer. It is well known that screening mammography has a decreased sensitivity for cancer detection in women with dense breasts. Over the past decade, there has been increased interest generated among patients, physicians, and legislators regarding how best to screen dense-breasted women culminating in 2009 with the passage of a breast density notification law in Connecticut...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29312973/critical-appraisal-of-chinese-2017-guideline-on-the-management-of-hepatocellular-carcinoma
#11
REVIEW
Di-Yang Xie, Zheng-Gang Ren, Jian Zhou, Jia Fan, Qiang Gao
Hepatocellular carcinoma (HCC) is the fourth most common and the third most lethal cancer in China. An updated version of consensus-based recommendations on the management of HCC has been recently published by a multidisciplinary group of Chinese experts including liver surgeons, hepatic oncologists, radiologists and pathologists. Major changes have been made to the diagnostic criteria. In addition to dynamic multi-detector computed tomography (CT) and magnetic resonance imaging (MRI), gadoxetic acid-enhanced MRI and contrast-enhanced ultrasound (CEUS) are added to the diagnostic imaging tests...
December 2017: Hepatobiliary Surgery and Nutrition
https://www.readbyqxmd.com/read/29312744/pathway-and-application-value-of-exploration-of-the-pulmonary-artery-by-endobronchial-ultrasound
#12
Peng Li, Cen Wu, Wei Zheng, Li Zhao
Background: The current standard methods for detecting pulmonary artery diseases are pulmonary artery enhanced computed tomography (CT) scan and pulmonary arteriography. However, some patients cannot tolerate these procedures for various reasons. The present study aimed to investigate the feasibility and operation process of endobronchial ultrasound (EBUS) in exploring the pulmonary artery. Methods: Based on normal contrast-enhanced chest CT images, the sites and process for exploring the pulmonary arteries were established...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29309906/extrapulmonary-small-cell-carcinoma-an-unfortunate-case-of-metastatic-disease
#13
Amie L Harvey, Tommy Yen, Anand Kunda
A 48- year-old man presented with weight loss and 3 weeks of right sided lower abdominal pain. Liver ultrasound and contrast-enhanced computed tomographic scan of the chest, abdomen, and pelvis revealed a 6.8 x 4.3 cm mass like thickening of ascending colon, with numerous hepatic lesions, enlarged mesenteric lymph nodes, peritoneal nodularity and multiple small (2-4 mm) pulmonary nodules concerning for widely metastatic disease (Figure A). A colonoscopy revealed an ulcerated right colon mass obliterating the lumen (Figure B)...
January 5, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29307931/common-and-uncommon-features-of-focal-splenic-lesions-on-contrast-enhanced-ultrasound-a-pictorial-review
#14
Julia D Zavariz, Eleni Konstantatou, Annamaria Deganello, Diana Bosanac, Dean Y Huang, Maria E Sellars, Paul S Sidhu
The characterization of focal splenic lesions by ultrasound can be quite challenging. The recent introduction of contrast-enhanced ultrasound (CEUS) has come to play a valuable role in the field of imaging splenic pathologies, offering the possibility of an ionizing radiation-free investigation. Because CEUS has been incorporated into everyday clinical practice, malignant diseases such as focal lymphomatous infiltration, metastatic deposits, benign cysts, traumatic fractures, and hemangiomas can now be accurately depicted and characterized without the need for further imaging...
November 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/29305613/optimized-time-resolved-echo-piv-ptv-measurements-elucidate-blood-flow-in-patients-with-left-ventricular-thrombus
#15
Kaushik Sampath, Thura T Harfi, Ricard/T George, Joseph Katz
Contrast ultrasound is a widely used clinical tool to obtain real-time qualitative blood flow assessments in the heart, liver, etc. Echocardiographic particle image velocimetry (echo-PIV) is a technique for obtaining quantitative velocity maps from contrast ultrasound images. However, unlike optical PIV, routine echo images are prone to non-uniform spatiotemporal variations in tracer distribution, making analysis difficult for standard PIV algorithms. This study introduces optimized procedures that integrate image enhancement, PIV and particle tracking velocimetry (PTV) to obtain reliable time-resolved 2D velocity distributions...
January 5, 2018: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29301827/thy1-targeted-microbubbles-for-ultrasound-molecular-imaging-of-pancreatic-ductal-adenocarcinoma
#16
Lotfi Abou-Elkacem, Huaijun Wang, Sayan M Chowdhury, Richard H Kimura, Sunitha V Bachawal, Sanjiv S Gambhir, Lu Tian, Juergen K Willmann
PURPOSE: To engineer a dual human and murine Thy1-binding single-chain-antibody ligand (Thy1-scFv) for contrast microbubble-enhanced ultrasound molecular imaging of pancreatic ductal adenocarcinoma (PDAC). EXPERIMENTAL DESIGN:  Thy1-scFv were engineered using yeast-surface-display techniques. Binding to soluble human and murine Thy1 and to Thy1-expressing cells was assessed by flow cytometry. Thy1-scFv was then attached to gas-filled microbubbles to create MB Thy1-scFv...
January 4, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29301450/effects-of-a-microbubble-ultrasound-contrast-agent-on-high-intensity-focused-ultrasound-for-uterine-fibroids-a-randomised-controlled-trial
#17
Yan Chen, Jing Jiang, Yuhua Zeng, Xiaobing Tian, Miao Zhang, Hong Wu, Honggui Zhou
OBJECTIVE: To investigate the effects of a microbubble ultrasound contrast agent on high-intensity focused ultrasound (HIFU) treatment of uterine fibroids. METHODS: A total of 120 patients with solitary uterine fibroid were randomly assigned into Groups A, B, C and D. Patients in Groups A and B received 1.5 ml of SonoVue, Groups C and D received 1.5 ml of saline before HIFU ablation. HIFU sonication started at 6 min after administration of SonoVue or saline in Groups A and C, whereas it started at 10 min in Groups B and D...
January 4, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29299367/contrast-enhanced-ultrasound-guided-biopsies-of-liver-lesions-not-visualized-on-standard-b-mode-ultrasound-preliminary-experience
#18
Sasan Partovi, Ziang Lu, Rivka Kessner, Alice Yu, Yasmine Ahmed, Indravadan J Patel, Dean A Nakamoto, Nami Azar
Background: To assess the technical success of contrast enhanced ultrasound (CEUS) guided biopsies of liver lesions poorly visualized on B-mode ultrasound. Methods: Patients were selected during the procedure based on the real-time clinical scenario of unsatisfactory B-mode ultrasound lesion visualization and all patients would have otherwise undergone CT guided liver lesion biopsy. A total of 26 patients underwent CEUS guided biopsy and were included in this retrospective analysis...
December 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29290798/ultrasound-molecular-imaging-of-vegfr-2-in-clear-cell-renal-cell-carcinoma-tracks-disease-response-to-antiangiogenic-and-notch-inhibition-therapy
#19
Juan D Rojas, Fanglue Lin, Yun-Chen Chiang, Anna Chytil, Diana C Chong, Victoria L Bautch, W Kimryn Rathmell, Paul A Dayton
Metastatic clear-cell renal cell carcinoma (ccRCC) affects thousands of patients worldwide each year. Antiangiogenic therapy has been shown to have beneficial effects initially, but resistance is eventually developed. Therefore, it is important to accurately track the response of cancer to different therapeutics in order to appropriately adjust the therapy to maximize efficacy. Change in tumor volume is the current gold standard for determining efficacy of treatment. However, functional variations can occur much earlier than measurable volume changes...
2018: Theranostics
https://www.readbyqxmd.com/read/29287999/the-dependence-of-glomerular-capillary-hemorrhage-induced-by-contrast-enhanced-diagnostic-ultrasound-on-microbubble-diameter
#20
Douglas L Miller, Xiaofang Lu, Chunyan Dou, Mario L Fabiilli, Charles C Church
A recently proposed two-criterion model for cavitational bioeffects in tissue with microbubbles (MBs) was tested. The glomerular capillary hemorrhage bioeffect was observed in rat kidney for contrast agent MB suspensions with mean diameters of 1.6, 3.1 and 5.5 µm. A diagnostic ultrasound machine was used at 3.6 MHz and 5.5 MHz for intermittent scans at power settings 2 dB apart. Petechial hemorrhage counts scored on the surface of the kidneys, and glomeruli were scored in histology. Thresholds for the petechial hemorrhage measurements were the same for the large and medium MB suspensions but substantially higher for the small MBs...
December 26, 2017: Ultrasound in Medicine & Biology
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