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https://www.readbyqxmd.com/read/29155555/medication-exposure-in-highly-adherent-psychiatry-patients
#1
Jeffrey J Sutherland, Thomas M Daly, Karen Jacobs, Elias A Khawam, Leo Pozuelo, Ryan D Morrison, Stephen B Milne, J Scott Daniels, Timothy Patrick Ryan
Medication exposure is dependent upon many factors, the single most important being if the patient took the prescribed medication as indicated. To assess medication exposure for psychotropic and other medication classes, we enrolled 115 highly adherent psychiatry patients prescribed five or more medications. In these patients, we measured 21 psychotropic and 38 non-psychotropic medications comprising a 59-medication multiplex assay panel. Strict enrollment criteria and reconciliation of the electronic health record medication list prior to study initiation produced a patient cohort that was compliant with 91% of their prescribed medications as determined by comparing medications detected empirically in blood to the electronic health record medication list...
November 20, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29151235/how-the-urge-to-kill-feels-articulations-of-emic-appetitive-aggression-experiences-among-former-forcefully-recruited-children-and-youth-in-the-acholi-region-of-northern-uganda
#2
Helle Harnisch, Anett Pfeiffer
Based on 10 months of fieldwork in the Acholi region of northern Uganda among youth and adults who were forcefully recruited into the Lord's Resistance Army (LRA) during the war, this article provides qualitative details to research on 'appetitive aggression.' Through two case-stories the article unfolds first person articulations of how 'appetitive aggression' is experienced as 'the urge to kill' and how it relates to the emic Acholi spiritual concept of 'cen'; a local Luo expression used to describe places and human beings possessed by evil spirits...
November 18, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/29131132/points-of-concern-in-post-acute-kidney-injury-management
#3
Jill Vanmassenhove, Raymond Vanholder, Norbert Lameire
The incidence of acute kidney injury (AKI) will in the future remain high, partly due to an increase in comorbidities and other AKI favoring factors such as the rise in high-risk diagnostic and therapeutic interventions. AKI has emerged as a major public health concern with high human and financial costs. It has recently been demonstrated that patients surviving an AKI episode show increased all-cause mortality, chronic kidney disease (CKD), ESRD, cardiovascular events, and reduced quality of life. Although it is important to acknowledge that, after an AKI episode, the risk of dying by far exceeds the risk of developing incident or progressive CKD and/or entering a maintenance renal replacement therapy (RRT) program, currently only a minority of patients are referred for renal follow-up, even after AKI-requiring RRT...
November 2, 2017: Nephron
https://www.readbyqxmd.com/read/29124788/need-for-multiscale-planning-for-conservation-of-urban-bats
#4
Travis Gallo, Elizabeth W Lehrer, Mason Fidino, R Julia Kilgour, Patrick J Wolff, Seth Magle
For over a century there have been continual efforts to incorporate nature into urban planning. These efforts - known as urban reconciliation- aim to manage and create habitats that support biodiversity within cities. Given that species select habitat at different spatial scales, understanding the scale at which urban species respond to their environment is critical to the success of urban reconciliation efforts. We assessed species-habitat relationships for common bat species at local (50-m), medium (500-m), and broad (1-km) spatial scales in the Chicago metropolitan area and predicted bat activity across the greater Chicago region...
November 10, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29124665/evaluation-of-definite-anaphylaxis-drug-allergy-alert-overrides-in-inpatient-and-outpatient-settings
#5
Adrian Wong, Diane L Seger, Sarah P Slight, Mary G Amato, Patrick E Beeler, Julie M Fiskio, David W Bates
INTRODUCTION: Drug-allergy interaction (DAI) alerts are generated when a known adverse sensitivity-inducing substance is prescribed. A recent study at our institution showed that providers overrode most DAI alerts, including those that warned against potentially life-threatening 'anaphylaxis'. OBJECTIVE: The aim of this study was to determine the rate of anaphylaxis overrides, the reasons for these overrides, whether the overrides were appropriate, and if harm occurred from overrides...
November 9, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/29123600/activities-performed-by-pharmacists-integrated-in-family-health-teams-results-from-a-web-based-survey
#6
Ulrika Gillespie, Lisa Dolovich, Simone Dahrouge
Objectives: Family health teams (FHTs), an interprofessional primary care practice model, were established in Ontario in 2005. As of October 2014, 191 FHT organizations were in operation, and 111 (58%) included one or several pharmacists. The objective of this study was to document the focus of pharmacist activities in FHTs. Approach: We invited all 155 known FHT pharmacists to a web-based survey. The survey was constructed using information obtained from previously done semi-structured telephone interviews with pharmacists working in FHTs...
November 2017: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/29121197/higher-accuracy-of-complex-medication-reconciliation-through-improved-design-of-electronic-tools
#7
Jan Horsky, Elizabeth A Drucker, Harley Z Ramelson
Objective: Investigate the accuracy of 2 different medication reconciliation tools integrated into electronic health record systems (EHRs) using a cognitively demanding scenario and complex medication history. Materials and Methods: Seventeen physicians reconciled medication lists for a polypharmacy patient using 2 EHRs in a simulation study. The lists contained 3 types of discrepancy and were transmitted between the systems via a Continuity of Care Document. Participants updated each EHR and their interactions were recorded and analyzed for the number and type of errors...
November 7, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29120613/formularity-software-for-automated-formula-assignment-of-natural-and-other-organic-matter-from-ultrahigh-resolution-mass-spectra
#8
Nikola Toliċ, Yina Liu, Andrey V Liyu, Yufeng Shen, Malak M Tfaily, Elizabeth B Kujawinski, Krista Longnecker, Li-Jung Kuo, Errol W Robinson, Ljiljana Paša-Tolić, Nancy J Hess
Ultrahigh resolution mass spectrometry, such as Fourier transform ion cyclotron resonance mass spectrometry (FT ICR MS), can resolve thousands of molecular ions in complex organic matrices. A Compound Identification Algorithm (CIA) was previously developed for automated elemental formula assignment for natural organic matter (NOM). In this work we describe software Formularity with a user friendly interface for CIA function and newly developed search function Isotopic Pattern Algorithm (IPA). While CIA assigns elemental formulas for compounds containing C, H, O, N, S, and P, IPA is capable of assigning formulas for compounds containing other elements...
November 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29120529/user-experience-and-care-for-older-people-transitioning-from-hospital-to-home-patients-and-carers-perspectives
#9
Jacqueline Allen, Alison M Hutchinson, Rhonda Brown, Patricia M Livingston
BACKGROUND: Transitioning from hospital to home is challenging for many older people living with chronic health conditions. Transitional care facilitates safe and timely transfer of patients between levels of care and across care settings and includes communication between practitioners, assessment and planning, preparation, medication reconciliation, follow-up care and self-management education. To date, there is limited understanding of how to actively involve care recipient service users in transitional care...
November 9, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29118037/nursing-home-evacuation-turns-medication-reconciliation-into-emergency
#10
Cheryl A Thompson
No abstract text is available yet for this article.
November 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29113563/multidimensional-knowledge-based-framework-is-an-essential-step-in-the-categorization-of-gene-sets-in-complex-disorders
#11
A Sreeja, K P Vinayan
In complex disorders, collaborative role of several genes accounts for the multitude of symptoms and the discovery of molecular mechanisms requires proper understanding of pertinent genes. Majority of the recent techniques utilize either single information or consolidate the independent outlook from multiple knowledge sources for assisting the discovery of candidate genes. In any case, given that various sorts of heterogeneous sources are possibly significant for quality gene prioritization, every source bearing data not conveyed by another, we assert that a perfect strategy ought to give approaches to observe among them in a genuine integrative style that catches the degree of each, instead of utilizing a straightforward mix of sources...
October 9, 2017: Journal of Bioinformatics and Computational Biology
https://www.readbyqxmd.com/read/29111835/improving-outcomes-in-adults-with-diabetes-through-an-interprofessional-collaborative-practice-program
#12
Jean Nagelkerk, Margaret E Thompson, Michael Bouthillier, Amy Tompkins, Lawrence J Baer, Jeff Trytko, Andrew Booth, Adam Stevens, Kayleah Groeneveld
In 2014, the Midwest Interprofessional Practice, Education and Research Center partnered with a Federally Qualified Health Center (FQHC) to implement an interprofessional collaborative practice (IPCP) education program to improve the health of adult patients with diabetes and to improve practice efficiency. This partnership included integrating an interprofessional team of students with the practice team. Twenty-five students and 20 staff engaged in the IPCP program, which included completion of educational modules on IPCP and implementation of daily huddles, focus patient visits, phone calls, team-based case presentations, medication reconciliation, and student-led group diabetes education classes...
November 7, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29107509/predictive-model-for-the-dutch-post-consumer-plastic-packaging-recycling-system-and-implications-for-the-circular-economy
#13
Marieke T Brouwer, Eggo U Thoden van Velzen, Antje Augustinus, Han Soethoudt, Steven De Meester, Kim Ragaert
The Dutch post-consumer plastic packaging recycling network has been described in detail (both on the level of packaging types and of materials) from the household potential to the polymeric composition of the recycled milled goods. The compositional analyses of 173 different samples of post-consumer plastic packaging from different locations in the network were combined to indicatively describe the complete network with material flow analysis, data reconciliation techniques and process technological parameters...
October 26, 2017: Waste Management
https://www.readbyqxmd.com/read/29105575/pharmacy-students-and-pharmacy-technicians-in-medication-reconciliation-a-review-of-the-current-literature
#14
Heather M Champion, Julia A Loosen, Korey A Kennelty
OBJECTIVE: A literature review was conducted to examine how pharmacy students and technicians have been utilized in medication reconciliation processes in an effort to evaluate expanded roles for pharmacy students and technicians. Data were summarized on accuracy of obtaining medication histories, time requirements, discrepancy identification, and cost savings. Limitations and areas for future research also were identified. DATA SOURCES: A search of PubMed, the Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and PsycINFO and a manual searching of bibliographies were performed...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29104760/noninvasive-vaccination-as-a-casus-belli-to-redeem-vaccine-value-in-the-face-of-anti-vaccine-movements
#15
De-Chu C Tang
Formidable anti-vaccine movements have been growing as a menace to disrupt beneficial vaccine programs. Although the vaccination-associated adverse effects commonly perceived by vaccine resisters usually represent over-reactions to rare manifestations, converging evidence shows that vaccination-associated health threats could be pervasive when systemic inflammation is considered as a side effect that oozes over time. An anti-vaccine movement thus may not be so unfounded even though the myriad cascades triggered by systemic inflammation have not been brought to a clear focus during any anti-vaccine campaign...
2017: Integrative Molecular Medicine
https://www.readbyqxmd.com/read/29103240/the-need-for-medication-reconciliation-increases-with-age
#16
Rima Rappaport, Zeev Arinzon, Jacob Feldman, Shiloh Lotan, Rachel Heffez-Aizenfeld, Yitshal Berner
BACKGROUND: Medication reconciliation (MR) at hospital admission, transfer, and discharge has been designated as a required hospital practice to reduce adverse drug events. OBJECTIVES: To perform MR among elderly patients admitted to the hospital and to determine factors that influence differences between the various lists of prescribed drugs as well as their actual consumption. METHODS: We studied patients aged 65 years and older who had been admitted to the hospital and were taking at least one prescription drug...
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29102998/development-of-a-clinical-pharmacy-model-within-an-australian-home-nursing-service-using-co-creation-and-participatory-action-research-the-visiting-pharmacist-vip-study
#17
Rohan A Elliott, Cik Yin Lee, Christine Beanland, Dianne P Goeman, Neil Petrie, Barbara Petrie, Felicity Vise, June Gray
OBJECTIVE: To develop a collaborative, person-centred model of clinical pharmacy support for community nurses and their medication management clients. DESIGN: Co-creation and participatory action research, based on reflection, data collection, interaction and feedback from participants and other stakeholders. SETTING: A large, non-profit home nursing service in Melbourne, Australia. PARTICIPANTS: Older people referred to the home nursing service for medication management, their carers, community nurses, general practitioners (GPs) and pharmacists, a multidisciplinary stakeholder reference group (including consumer representation) and the project team...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29081237/universal-classifications-national-approaches-and-specific-situations-a-comparative-study-on-the-conceptualization-of-nodding-syndrome-in-uganda-and-tanzania
#18
Karin van Bemmel, Kim van der Weegen
This paper presents a comparative study on conceptualizations of the poorly understood nodding syndrome (NS) in Uganda and Tanzania. NS has been constructed as a biomedical category to serve global health discourse as well as national contexts of managing the condition. The paper looks into the shifting meanings and conceptualizations of NS in the affected areas of Kitgum (UG) and Mahenge (TZ) district. The perceived universality of biomedical classifications is problematized as conflicting with the specific contexts of lucluc and kifafa cha kusinzia...
October 30, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/29078707/continuous-care-provided-through-comprehensive-medication-management-in-an-acute-care-practice-model
#19
T David Marr, Nicole R Pinelli, Jamie A Jarmul, Kayla M Waldron, Stephen F Eckel, Jonathan D Cicci, Jill S Bates, Lindsey B Amerine
BACKGROUND: Pharmacy practice models that foster pharmacists' accountability for medication-related outcomes are imperative for the profession. Comprehensive medication management (CMM) is an opportunity to advance patient care. OBJECTIVE: The objective of this study was to evaluate the impact of a CMM practice model in the acute care setting on organizational, patient, and financial outcomes. METHODS: Three adult service lines focused on at-risk patients identified using internal risk stratification methodology were implemented...
October 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29076113/a-knowledge-modeling-approach-to-integrate-multiple-clinical-practice-guidelines-to-provide-evidence-based-clinical-decision-support-for-managing-comorbid-conditions
#20
Samina Abidi
Clinical management of comorbidities is a challenge, especially in a clinical decision support setting, as it requires the safe and efficient reconciliation of multiple disease-specific clinical procedures to formulate a comorbid therapeutic plan that is both effective and safe for the patient. In this paper we pursue the integration of multiple disease-specific Clinical Practice Guidelines (CPG) in order to manage co-morbidities within a computerized Clinical Decision Support System (CDSS). We present a CPG integration framework-termed as COMET (Comorbidity Ontological Modeling & ExecuTion) that manifests a knowledge management approach to model, computerize and integrate multiple CPG to yield a comorbid CPG knowledge model that upon execution can provide evidence-based recommendations for handling comorbid patients...
October 26, 2017: Journal of Medical Systems
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