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https://www.readbyqxmd.com/read/28630747/global-patterns-in-coronavirus-diversity
#1
Simon J Anthony, Christine K Johnson, Denise J Greig, Sarah Kramer, Xiaoyu Che, Heather Wells, Allison L Hicks, Damien O Joly, Nathan D Wolfe, Peter Daszak, William Karesh, W I Lipkin, Stephen S Morse, Jonna A K Mazet, Tracey Goldstein
Since the emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrom Coronavirus (MERS-CoV) it has become increasingly clear that bats are important reservoirs of CoVs. Despite this, only 6% of all CoV sequences in GenBank are from bats. The remaining 94% largely consist of known pathogens of public health or agricultural significance, indicating that current research effort is heavily biased towards describing known diseases rather than the 'pre-emergent' diversity in bats...
January 2017: Virus Evolution
https://www.readbyqxmd.com/read/28630644/isometric-gene-tree-reconciliation-revisited
#2
Broňa Brejová, Askar Gafurov, Dana Pardubská, Michal Sabo, Tomáš Vinař
BACKGROUND: Isometric gene tree reconciliation is a gene tree/species tree reconciliation problem where both the gene tree and the species tree include branch lengths, and these branch lengths must be respected by the reconciliation. The problem was introduced by Ma et al. in 2008 in the context of reconstructing evolutionary histories of genomes in the infinite sites model. RESULTS: In this paper, we show that the original algorithm by Ma et al. is incorrect, and we propose a modified algorithm that addresses the problems that we discovered...
2017: Algorithms for Molecular Biology: AMB
https://www.readbyqxmd.com/read/28629301/discrepancies-identified-through-a-telephone-based-student-led-initiative-for-medication-reconciliation-in-ambulatory-psychiatry
#3
Marie E Albano, Jolene R Bostwick, Kristen M Ward, Thomas Fluent, Hae Mi Choe
PURPOSE: To identify the number of medication discrepancies following establishment of a telephone-based, introductory pharmacy practice experience student-driven, medication reconciliation service for new patients in an ambulatory psychiatry clinic. Secondarily, to identify factors impacting medication discrepancies to better target medication profiles to reconcile and to evaluate whether the implementation of a call schedule effected clinic no-show rates. METHODS: This was a retrospective analysis of a telephone-based medication reconciliation service from June 2014 to January 2016...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28626270/impact-of-a-student-pharmacist-driven-medication-reconciliation-and-antidepressant-treatment-history-project-at-a-depression-clinic-a-pilot-study
#4
Stella S Tang, Leanna Jaward, Kristen Ward, Sagar V Parikh, Jolene R Bostwick
OBJECTIVES: To improve treatment of patients with depression, a new pilot service project involving student pharmacists who would conduct medication reconciliation and review of antidepressant treatment history was created and evaluated. EXPERIMENTAL DESIGN: A prospective study conducted at the University of Michigan Depression Center. PRINCIPAL OBSERVATIONS: From an initial sample of 78 referrals, 41 subjects were reached by phone, with 34 completing medication reconciliation and antidepressant treatment history...
May 15, 2017: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/28622673/exact-algorithms-for-duplication-transfer-loss-reconciliation-with-non-binary-gene-trees
#5
Misagh Kordi, Mukul S Bansal
Duplication-Transfer-Loss (DTL) reconciliation is a powerful method for studying gene family evolution in the presence of horizontal gene transfer. DTL reconciliation seeks to reconcile gene trees with species trees by postulating speciation, duplication, transfer, and loss events. Efficient algorithms exist for finding optimal DTL reconciliations when the gene tree is binary. In practice, however, gene trees are often non-binary due to uncertainty in the gene tree topologies, and DTL reconciliation with non-binary gene trees is known to be NP-hard...
June 1, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28610942/evaluation-of-a-pharmacist-managed-electrolyte-protocol-in-outpatients-on-antiarrhythmic-medications
#6
Victor P Long Iii, Cynthia A Carnes, Jonathan Vecchiet, Mahmoud Houmsse, Andrea Hirsch, Melissa J Snider
OBJECTIVE: To evaluate the effectiveness of a pharmacist-managed treatment protocol in achieving and maintaining serum potassium level ([K(+)]) in the desired range. SETTING: Antiarrhythmic Medications Clinic, The Ohio State University Wexner Medical Center, Columbus, Ohio, from 2009 to 2013. PRACTICE DESCRIPTION: Patients are referred for antiarrhythmic monitoring at this pharmacist-run, electrophysiologist-supervised clinic. Each visit includes medication reconciliation for drug interaction identification, patient interview for potential adverse effects or arrhythmia symptoms, patient education, and drug therapy monitoring through ordering and review of objective testing...
June 10, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28596445/development-of-a-new-care-model-for-hospitalized-children-with-medical-complexity
#7
Christine M White, Joanna E Thomson, Angela M Statile, Katherine A Auger, Ndidi Unaka, Matthew Carroll, Karen Tucker, Derek Fletcher, David E Hall, Jeffrey M Simmons, Patrick W Brady
Children with medical complexity are a rapidly growing inpatient population with frequent, lengthy, and costly hospitalizations. During hospitalization, these patients require care coordination among multiple subspecialties and their outpatient medical homes. At a large freestanding children's hospital, a new inpatient model of care was developed in an effort to consistently provide coordinated, family-centered, and efficient care. In addition to expanding the multidisciplinary team to include a pharmacist, dietician, and social worker, the team redesign included: (1) medication reconciliation rounds, (2) care coordination rounds, and (3) multidisciplinary weekly handoff with outpatient providers...
June 8, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28592986/correlates-of-early-neonatal-feeding-practice%C3%A2-in-dabat-hdss-site-northwest-ethiopia
#8
Terefe Derso, Gashaw Andargie Biks, Amare Tariku, Nigusie Birhan Tebeje, Zemichael Gizaw, Kindie Fentahun Muchie, Alemayehu Shimeka, Yigzaw Kebede, Solomon Mekonnen Abebe, Mezgebu Yitayal, Tadesse Awoke Ayele, Mamo Wubeshet, Temesgen Azmeraw, Melkamu Birku, Abel Fekadu, Geta Asrade, Abebaw Gebeyehu, Adino Tesfahun, Kassahun Alemu
BACKGROUND: Delaying the start of breastfeeding and giving prelacteal feeding leads to a significant increase in neonatal and infant deaths, particularly in a resource limited countries, like Ethiopia. Therefore, this study aimed to assess early neonatal feeding practice and its determinants in Dabat HDSS site, northwest Ethiopia. METHODS: The census for the reconciliation of the surveillance of the Dabat Health and Demographic Surveillance System (HDSS) site was conducted from October to December 2014...
2017: International Breastfeeding Journal
https://www.readbyqxmd.com/read/28583091/reconciliation-feasibility-in-the-presence-of-gene-duplication-loss-and-coalescence-with-multiple-individuals-per-species
#9
Jennifer Rogers, Andrew Fishberg, Nora Youngs, Yi-Chieh Wu
BACKGROUND: In phylogenetics, we often seek to reconcile gene trees with species trees within the framework of an evolutionary model. While the most popular models for eukaryotic species allow for only gene duplication and gene loss or only multispecies coalescence, recent work has combined these phenomena through a reconciliation structure, the labeled coalescent tree (LCT), that simultaneously describes the duplication-loss and coalescent history of a gene family. However, the LCT makes the simplifying assumption that only one individual is sampled per species whereas, with advances in gene sequencing, we now have access to multiple samples per species...
June 5, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28569128/development-of-a-student-led-ambulatory-medication-reconciliation-program-at-an-academic-institution
#10
Aimon C Miranda, Jaclyn D Cole, Melissa J Ruble, Erini S Serag-Bolos
OBJECTIVES: To integrate fourth-year student pharmacists on advanced pharmacy practice experience (APPE) rotations within several different ambulatory clinics to perform medication reconciliations and enhance interdisciplinary practice. METHODS: The study design was a descriptive, prospective multisite study among a variety of ambulatory care outpatient clinics. Student pharmacists were partnered with physicians to conduct medication reconciliations during clinic visits for 4 hours per week, with data collection from January 2016 to September 2016...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28558070/vocalizations-during-post-conflict-affiliations-from-victims-toward-aggressors-based-on-uncertainty-in-japanese-macaques
#11
Noriko Katsu, Kazunori Yamada, Masayuki Nakamichi
We investigated the use of vocalizations called "grunts," "girneys," and "coos" accompanied by post-conflict affiliative interaction between former opponents (reconciliation) in Japanese macaques (Macaca fuscata). Although reconciliation functions to repair bonds, such interactions sometimes entail risks of receiving further aggression. Vocalizations can be used at a distance from the former opponent; thus, we predict that vocalizations are used particularly by victims of a conflict, and are frequently used in situations of uncertainty when it is difficult for them to estimate whether the former opponent will resume aggression...
2017: PloS One
https://www.readbyqxmd.com/read/28557524/a-call-for-a-statewide-medication-reconciliation-program
#12
Elizabeth Askin, David Margolius
In the outpatient setting, it is exceedingly difficult to know what medications our patients have been prescribed and are taking. Each encounter with a specialist, hospital, or pharmacy can generate a change to a patient's list of medications, and in most systems, this information is not communicated back to the primary care practice's electronic health record-the exception being opiate prescriptions. Prescription drug monitoring programs in 48 states list every opiate prescription, the name of the prescriber, and the date and location the prescription was picked up...
October 1, 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/28557517/economic-value-of-pharmacist-led-medication-reconciliation-for-reducing-medication-errors-after-hospital-discharge
#13
Mehdi Najafzadeh, Jeffrey L Schnipper, William H Shrank, Steven Kymes, Troyen A Brennan, Niteesh K Choudhry
OBJECTIVES: Medication discrepancies at the time of hospital discharge are common and can harm patients. Medication reconciliation by pharmacists has been shown to prevent such discrepancies and the adverse drug events (ADEs) that can result from them. Our objective was to estimate the economic value of nontargeted and targeted medication reconciliation conducted by pharmacists and pharmacy technicians at hospital discharge versus usual care. STUDY DESIGN: Discrete-event simulation model...
October 2016: American Journal of Managed Care
https://www.readbyqxmd.com/read/28553240/the-role-of-the-human-mirror-neuron-system-in-supporting-communication-in-a-digital-world
#14
REVIEW
Kelly Dickerson, Peter Gerhardstein, Alecia Moser
Humans use both verbal and non-verbal communication to interact with others and their environment and increasingly these interactions are occurring in a digital medium. Whether live or digital, learning to communicate requires overcoming the correspondence problem: There is no direct mapping, or correspondence between perceived and self-produced signals. Reconciliation of the differences between perceived and produced actions, including linguistic actions, is difficult and requires integration across multiple modalities and neuro-cognitive networks...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28550698/boomr-better-coordinated-cross-sectoral-medication-reconciliation-for%C3%A2-residential-care
#15
Vincent Vuong, Denis O'Donnell, Hrishikesh Navare, Debra Merrill, Michal Racki, Sheila Burton, Lori Anderson, Carla Beaton
There is evidence that medication errors often arise during the transition of residents from acute care to long-term care (LTC) homes due to lapses in communication and documentation. Better Coordinated Cross-Sectoral Medication Reconciliation (BOOMR) is an integrated practice change improving medication safety during patient transitions through the health system. Our Medication Reconciliation (MedRec) redesign improved patient engagement using "the patient's story," increased quality of information, workflow efficiency and reduced unnecessary medications...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28549580/hyperkalemia-and-cardiac-arrest-associated-with-glucose-replacement-in-a-patient-on-spironolactone
#16
Ryan Offman, Amanda Paden, Adam Gwizdala, James Fletcher Reeves
We present a case of hypoglycemia, which after intravenous glucose replacement, led to cardiac arrest secondary to a profound extracellular potassium shift. The patient was on spironolactone therapy which is known to cause aldosterone resistance (which inhibits the body's ability to prevent potassium shifts) [1]. Physicians typically review medications that cause hypoglycemia, but other medications may interfere with potassium homeostasis with administration of glucose. Knowledge of this case may prompt further monitoring, repeat lab testing, and careful medication reconciliation before discharging a patient with risk for aldosterone resistance...
May 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28543664/comparison-of-male-conflict-behavior-in-chimpanzees-pan-troglodytes-and-bonobos-pan-paniscus-with-specific-regard-to-coalition-and-post-conflict-behavior
#17
Martin Surbeck, Christophe Boesch, Cédric Girard-Buttoz, Catherine Crockford, Gottfried Hohmann, Roman M Wittig
Coalitions among males during within group conflicts have a strong influence on the competitive and social environment within social groups. To evaluate possible variation in the occurrence of such coalitions in our closest relatives, chimpanzees and bonobos, we compared male aggression and coalitionary behavior in two natural communities, one of each species, with a similar size and composition. Furthermore we compared affiliative behavior that might be related to coalition formation among males. We found higher frequencies of aggression and a greater likelihood to form coalitions during within-group conflicts among wild male chimpanzees at Taï compared to wild male bonobos at LuiKotale...
June 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28543391/medication-discrepancies-in-the-dental-record-and-impact-of-pharmacist-led-intervention
#18
Hailey J Choi, Autumn L Stewart, Chunhao Tu
BACKGROUND: Patients frequently use medications with potential implications for oral health and dental procedures, yet little is known about the accuracy of medication lists available to dentists. The aims of this study were to describe the frequency and clinical implications of medication discrepancies in the dental record (phase 1) and to evaluate the impact of pharmacist intervention on medication reconciliation processes in dental practice (phase 2). METHODS: A prospective, single-centre study evaluating adults receiving dental care was conducted...
May 20, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28542981/dental-providers-and-pharmacists-a-call-for-enhanced-interprofessional-collaboration
#19
Henning Lygre, Reidun Lisbet Skeide Kjome, Hailey Choi, Autumn L Stewart
Reports concerning medication discrepancies in dental records indicate that the concept of interprofessional collaboration between the dental team and pharmacists should be considered at all educational levels in dentistry and pharmacy. Inclusion of oral health as a therapeutic area in didactic pharmacy curricula is needed. Early exposure of dental students and student pharmacists to collaborative practices through interprofessional educational experiences may create a higher degree of awareness of the role of each profession and the potential to improve patient outcomes...
May 21, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28542267/discerning-morpho-anatomical-physiological-and-molecular-multiformity-in-cultivated-and-wild-genotypes-of-lentil-with-reconciliation-to-salinity-stress
#20
Dharmendra Singh, Chandan Kumar Singh, Shanti Kumari, Ram Sewak Singh Tomar, Sourabh Karwa, Rajendra Singh, Raja Bahadur Singh, Susheel Kumar Sarkar, Madan Pal
One hundred and sixty two genotypes of different Lens species were screened for salinity tolerance in hydroponics at 40, 80 and 120 mM sodium chloride (NaCl) for 30 d. The germination, seedling growth, biomass accumulation, seedling survivability, salinity scores, root and shoot anatomy, sodium ion (Na+), chloride ion (Cl-) and potassium ion (K+) concentrations, proline and antioxidant activities were measured to evaluate the performance of all the genotypes. The results were compared in respect of physiological (Na+, K+ and Cl-) and seed yield components obtained from field trials for salinity stress conducted during two years...
2017: PloS One
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