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https://www.readbyqxmd.com/read/27911801/mechanical-bounds-to-transcriptional-noise
#1
Stuart A Sevier, David A Kessler, Herbert Levine
Over the past several decades it has been increasingly recognized that stochastic processes play a central role in transcription. Although many stochastic effects have been explained, the source of transcriptional bursting (one of the most well-known sources of stochasticity) has continued to evade understanding. Recent results have pointed to mechanical feedback as the source of transcriptional bursting, but a reconciliation of this perspective with preexisting views of transcriptional regulation is lacking...
November 22, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27909369/mobilizing-reconciliation-implications-of-the-truth-and-reconciliation-commission-report-for-physiotherapy-in-canada
#2
EDITORIAL
Katie Gasparelli, Hilary Crowley, Moni Fricke, Brooke McKenzie, Sarah Oosman, Stephanie A Nixon
No abstract text is available yet for this article.
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27896880/a-community-based-cross-sectional-survey-of-medication-utilization-among-chronic-disease-patients-in-china
#3
Mark A Strand, Kirstin Gramith, Macy Royston, Xiaoxi Wang, Judith Perry, Curt Elliott
OBJECTIVES: To determine medication use patterns and associated health outcomes in Chinese individuals with diabetes, hypertension or hyperlipidaemia. METHODS: This community-based cross-sectional study was done in a north China city of 300 000 people. Participants were recruited by poster and phone call through Community Health Centres. Data were collected on 638 Chinese individuals. Interviews were done to screen for disease and health behaviours. Fasting blood was collected and analyzed...
November 29, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27890810/interaction-of-language-auditory-and-memory-brain-networks-in-auditory-verbal-hallucinations
#4
REVIEW
Branislava Ćurčić-Blake, Judith Ford, Daniela Hubl, Natasza D Orlov, Iris E Sommer, Flavie Waters, Paul Allen, Renaud Jardri, Peter W Woodruff, David Olivier, Christoph Mulert, Todd S Woodward, André Aleman
Auditory verbal hallucinations (AVH) occur in psychotic disorders, but also as a symptom of other conditions and even in healthy people. Several current theories on the origin of AVH converge, with neuroimaging studies suggesting that the language, auditory and memory/limbic networks are of particular relevance. However, reconciliation of these theories with experimental evidence is missing. We review 50 studies investigating functional (EEG and fMRI) and anatomic (diffusion tensor imaging) connectivity in these networks, and explore the evidence supporting abnormal connectivity in these networks associated with AVH...
November 24, 2016: Progress in Neurobiology
https://www.readbyqxmd.com/read/27890453/transition-of-care-a-set-of-pharmaceutical-interventions-improves-hospital-discharge-prescriptions-from-an-internal-medicine-ward
#5
Marine Neeman, Maria Dobrinas, Sophie Maurer, Damien Tagan, Annelore Sautebin, Anne-Laure Blanc, Nicolas Widmer
BACKGROUND: Continuity of care between hospitals and community pharmacies needs to be improved to ensure medication safety. This study aimed to evaluate whether a set of pharmaceutical interventions to prepare hospital discharge facilitates the transition of care. METHODS: This study took place in the internal medicine ward and in surrounding community pharmacies. The intervention group's patients underwent a set of pharmaceutical interventions during their hospital stay: medication reconciliation at admission, medication review, and discharge planning...
November 24, 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27887032/provider-perception-of-pharmacy-services-in-the-patient-centered-medical-home
#6
Nicole P Albanese, Alyssa M Pignato, Scott V Monte
BACKGROUND: Despite the positive data on clinical outcomes, cost savings, and provider experience, no study has surveyed providers to evaluate what pharmacy services they find to be worthwhile. OBJECTIVE: To determine what clinical, cost/access, and educational pharmacy services providers in a patient-centered medical home (PCMH) consider worthwhile and the perceived barriers to successful pharmacist incorporation. METHODS: A cross-sectional online survey was distributed to primary care physicians, nurse practitioners, and physician assistants in a PCMH physician group...
November 24, 2016: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27884844/medication-reconciliation-as-a-medication-safety-initiative-in-ethiopia-a-study-protocol
#7
Alemayehu B Mekonnen, Andrew J McLachlan, Jo-Anne E Brien, Desalew Mekonnen, Zenahebezu Abay
INTRODUCTION: Medication related adverse events are common, particularly during transitions of care, and have a significant impact on patient outcomes and healthcare costs. Medication reconciliation (MedRec) is an important initiative to achieve the Quality Use of Medicines, and has been adopted as a standard practice in many developed countries. However, the impact of this strategy is rarely described in Ethiopia. The aims of this study are to explore patient safety culture, and to develop, implement and evaluate a theory informed MedRec intervention, with the aim of minimising the incidence of medication errors during hospital admission...
November 24, 2016: BMJ Open
https://www.readbyqxmd.com/read/27884401/the-make-love-not-war-ape-bonobos-and-late-twentieth-century-explanations-for-war-and-peace
#8
Deborah Weinstein
Why do people fight wars? Following the devastation of the Second World War, this question became particularly pressing. Postwar scholars in the human sciences, from political science to anthropology, investigated the role of human nature in the causes of war even as they debated the very meaning of human nature itself. Among the wide-ranging efforts of postwar social and behavioral scientists to explain the causes of war, research on primate aggression became a compelling approach to studying the evolution of human warfare...
November 21, 2016: Endeavour
https://www.readbyqxmd.com/read/27882865/community-perceptions-on-domestic-violence-against-pregnant-women-in-nepal-a-qualitative-study
#9
Kunta Devi Pun, Jennifer J Infanti, Rajendra Koju, Berit Schei, Elisabeth Darj
BACKGROUND: Globally, knowledge of health sector options to respond to domestic violence during pregnancy is increasing, but this topic is under-investigated in Nepal. This gap affects the provision of adequate antenatal care services and understanding of factors that influence women's willingness and ability to use available services. It is critical to know more about the social norms in a community that promote and prevent women experiencing domestic violence from seeking antenatal care...
2016: Global Health Action
https://www.readbyqxmd.com/read/27882720/using-our-good-minds-to-foster-reconciliation-a-story-of-optimism
#10
David Newhouse
No abstract text is available yet for this article.
November 2016: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/27882719/mediating-the-space-between-voices-of-indigenous-youth-and-voices-of-educators-in-service-of-reconciliation
#11
Susan D Dion
No abstract text is available yet for this article.
November 2016: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/27882716/toward-a-sociology-of-the-reconciliation-of-conflicting-desires
#12
Susan O'Donnell, David Perley
Desire-based research provides people and communities the opportunity to share their dreams and hopes for a better future. However, conflicting desires are difficult to reconcile. We suggest that sociological research to understand conflicting desires is required to support reconciliation work by Indigenous and non-Indigenous people in Canada. Our contribution begins by identifying much of current and past sociological research about Indigenous people and communities as damaged-centered, that is, identifying problems and obstacles in the hope that the knowledge will lead to change...
November 2016: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/27882711/reconciliation-in-the-context-of-settler-colonial-gender-violence-how-do-we-reconcile-with-an-abuser
#13
Julie Kaye
No abstract text is available yet for this article.
November 2016: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/27882680/reconciling-conceptualisations-of-the-body-and-person-centred-care-of-the-older-person-with-cognitive-impairment-in-the-acute-care-setting
#14
Carole Rushton, David Edvardsson
In this article, we sought reconciliation between the "body-as-representation" and the "body-as-experience," that is, how the body is represented in discourse and how the body of older people with cognitive impairment is experienced. We identified four contemporary "technologies" and gave examples of these to show how they influence how older people with cognitive impairment are often represented in acute care settings. We argued that these technologies may be mediated further by discourses of ageism and ableism which can potentiate either the repressive or productive tendencies of these technologies resulting in either positive or negative care experiences for the older person and/or their carer, including nurses...
November 23, 2016: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/27881149/antipsychotic-prescribing-patterns-during-and-after-critical-illness-a-prospective-cohort-study
#15
Jason E Tomichek, Joanna L Stollings, Pratik P Pandharipande, Rameela Chandrasekhar, E Wesley Ely, Timothy D Girard
BACKGROUND: Antipsychotics are used to treat delirium in the intensive care unit (ICU) despite unproven efficacy. We hypothesized that atypical antipsychotic treatment in the ICU is a risk factor for antipsychotic prescription at discharge, a practice that might increase risk since long-term use is associated with increased mortality. METHODS: After excluding patients on antipsychotics prior to admission, we examined antipsychotic use in a prospective cohort of ICU patients with acute respiratory failure and/or shock...
November 24, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27881054/transition-of-care-for-patients-with-diabetes
#16
Patricia Garnica
BACKGROUND: Diabetes is a common chronic condition among adults that can complicate the transition from the hospital to the community. Hospital readmission is an important contributor to total medical expenditures and is an emerging indicator of quality of care. Failure to acknowledge diabetes transition of care is associated with increased emergency department visits and 30-day readmissions. METHODS: Literature review of transition of care models, sample tools and processes are presented...
November 22, 2016: Current Diabetes Reviews
https://www.readbyqxmd.com/read/27870713/the-frequency-of-unplanned-rehospitalization-and-associated-factors-in-gyneoncology-patients-a-retrospective-study
#17
Gul Pinar, Ayse Akalin, Hulya Erbaba, Gokce Banu Acar, Filiz Avsar, Tevfik Pinar
OBJECTIVE: In this study, we aim to analyze rate and associated factors with unplanned rehospitalization in gynecological cancer patients. MATERIALS AND METHODS: The electronic database query (2007 to 2014) was used to evaluate rehospitalization rates within 90 days of index admission in patients with gynecological cancer. Multivariable logistic regression was used to identify factors associated with rehospitalization. RESULTS: Mean patient age was 59...
November 17, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27862663/the-insight-and-challenge-of-reflexive-practice-in-an-ethnographic-study-of-black-traumatically-injured-patients-in-philadelphia
#18
Sara F Jacoby
The integrity of critical ethnography requires engagement in reflexive practice at all phases of the research process. In this discussion paper, I explore the insights and challenges of reflexive practice in an ethnographic study of the recovery experiences of black trauma patients in a Philadelphia hospital. Observation and interviews were conducted with twelve patients who were admitted to trauma-designated units of the hospital over the course of a year. During fieldwork, I learned the ways that my background as a professional nurse structured my way of being in clinical space and facilitated a particular interpretation of clinical culture...
November 15, 2016: Nursing Inquiry
https://www.readbyqxmd.com/read/27852240/identification-of-priorities-for-improvement-of-medication-safety-in-primary-care-a-prioritize-study
#19
Lorainne Tudor Car, Nikolaos Papachristou, Joseph Gallagher, Rajvinder Samra, Kerri Wazny, Mona El-Khatib, Adrian Bull, Azeem Majeed, Paul Aylin, Rifat Atun, Igor Rudan, Josip Car, Helen Bell, Charles Vincent, Bryony Dean Franklin
BACKGROUND: Medication error is a frequent, harmful and costly patient safety incident. Research to date has mostly focused on medication errors in hospitals. In this study, we aimed to identify the main causes of, and solutions to, medication error in primary care. METHODS: We used a novel priority-setting method for identifying and ranking patient safety problems and solutions called PRIORITIZE. We invited 500 North West London primary care clinicians to complete an open-ended questionnaire to identify three main problems and solutions relating to medication error in primary care...
November 16, 2016: BMC Family Practice
https://www.readbyqxmd.com/read/27850912/1276-standardized-daily-medication-reconciliation-in-the-surgical-icu
#20
Christopher Tainter, Kimberly Pollock, E O'Brien, Jarone Lee, Farivar Jahanasouz, Angela Meier
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
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