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https://www.readbyqxmd.com/read/28334218/reconciliation-between-operational-taxonomic-units-and-species-boundaries
#1
Mohamed Mysara, Peter Vandamme, Ruben Props, Frederiek-Maarten Kerckhof, Natalie Leys, Nico Boon, Jeroen Raes, Pieter Monsieurs
The development of high-throughput sequencing technologies has revolutionized the field of microbial ecology via 16S rRNA gene amplicon sequencing approaches. Clustering those amplicon sequencing reads into Operational Taxonomic Units (OTUs) using a fixed cut-off is a commonly used approach to estimate microbial diversity. A 97% threshold was chosen with the intended purpose that resulting OTUs could be interpreted as a proxy for a bacterial species. Our results show that the robustness of such a generalized cut-off is questionable when applied to short amplicons only covering one or two variable regions of the 16S rRNA gene...
March 10, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/28333697/medication-reconciliation-during-hospitalization-and-in-hospital-home-interface-an-observational-retrospective-study
#2
Elisabetta Volpi, Alessandro Giannelli, Giulio Toccafondi, Monica Baroni, Sara Tonazzini, Stefania Alduini, Stefania Biagini, Rosa Gini, Tommaso Bellandi, Michele Emdin
OBJECTIVE: Medication errors are one of the leading causes of patient harms. Medication reconciliation is a fundamental process that to be effective, it should be embraced during each single care transition. Our objectives were to investigate current medication reconciliation practices in the 2 Fondazione Toscana Gabriele Monasterio hospitals and comprehensively assess the quality of medication reconciliation practices between inpatient and outpatient care by analyzing the medication patterns 6 months before admission, during hospitalization, and 9 months after discharge for a selected group of patients with cardiovascular diseases...
March 22, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28331870/drug-drug-interactions-the-importance-of-medication-reconciliation
#3
Mahin Jamshidi Makiani, Somayyeh Nasiripour, Mahnaz Hosseini, Alireza Mahbubi
No abstract text is available yet for this article.
January 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28327557/deterministic-secure-quantum-communication-using-a-single-d-level-system
#4
Dong Jiang, Yuanyuan Chen, Xuemei Gu, Ling Xie, Lijun Chen
Deterministic secure quantum communication (DSQC) can transmit secret messages between two parties without first generating a shared secret key. Compared with quantum key distribution (QKD), DSQC avoids the waste of qubits arising from basis reconciliation and thus reaches higher efficiency. In this paper, based on data block transmission and order rearrangement technologies, we propose a DSQC protocol. It utilizes a set of single d-level systems as message carriers, which are used to directly encode the secret message in one communication process...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28323749/importance-of-medication-reconciliation-tizanidine-induced-hepatitis
#5
Dalvir Gill, Fatme Allam, Jennifer Boyle
No abstract text is available yet for this article.
March 17, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28320309/correlated-duplications-and-losses-in-the-evolution-of-palmitoylation-writer-and-eraser-families
#6
Stijn Wittouck, Vera van Noort
BACKGROUND: Protein post-translational modifications (PTMs) change protein properties. Each PTM type is associated with domain families that apply the modification (writers), remove the modification (erasers) and bind to the modified sites (readers) together called toolkit domains. The evolutionary origin and diversification remains largely understudied, except for tyrosine phosphorylation. Protein palmitoylation entails the addition of a palmitoyl fatty acid to a cysteine residue. This PTM functions as a membrane anchor and is involved in a range of cellular processes...
March 20, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28319907/the-impact-of-welfare-reform-on-the-health-insurance-coverage-utilization-and-health-of-low-education-single-mothers
#7
Kimberly Narain, Marianne Bitler, Ninez Ponce, Gerald Kominski, Susan Ettner
The Personal Responsibility Work Opportunity and Reconciliation Act (PRWORA) of 1996 imposed time limits on the receipt of welfare cash benefits and mandated cash benefit sanctions for failure to meet work requirements. Many studies examining the health implications of PRWORA have found associated declines in health insurance coverage and healthcare utilization among single mothers but no impact of PRWORA on health outcomes. A limitation of this literature is that most studies cover a time period before time limits were implemented in all states and also before individuals began actually timing out...
March 11, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28318270/prediction-of-stable-ground-state-lithium-polyhydrides-under-high-pressures
#8
Yangmei Chen, Hua Y Geng, Xiaozhen Yan, Yi Sun, Qiang Wu, Xiangrong Chen
Hydrogen-rich compounds are important for understanding the dissociation of dense molecular hydrogen, as well as searching for room temperature Bardeen-Cooper-Schrieffer (BCS) superconductors. A recent high pressure experiment reported the successful synthesis of novel insulating lithium polyhydrides above 130 GPa. However, the results are in sharp contrast to a previous theoretical prediction by the PBE functional that around this pressure range all lithium polyhydrides (LiHn (n = 2-8)) should be metallic...
March 20, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28316640/on-the-computational-complexity-of-the-maximum-parsimony-reconciliation-problem-in-the-duplication-loss-coalescence-model
#9
Daniel Bork, Ricson Cheng, Jincheng Wang, Jean Sung, Ran Libeskind-Hadas
BACKGROUND: Phylogenetic tree reconciliation is a widely-used method for inferring the evolutionary histories of genes and species. In the duplication-loss-coalescence (DLC) model, we seek a reconciliation that explains the incongruence between a gene and species tree using gene duplication, loss, and deep coalescence events. In the maximum parsimony framework, costs are associated with these event types and a reconciliation is sought that minimizes the total cost of the events required to map the gene tree onto the species tree...
2017: Algorithms for Molecular Biology: AMB
https://www.readbyqxmd.com/read/28302923/improving-medication-safety-and-diabetes-management-in-hong-kong-a-multidisciplinary-approach
#10
A Ys Chung, S Anand, I Ck Wong, K Cb Tan, C Ff Wong, W Cm Chui, E W Chan
INTRODUCTION: Patients with diabetes often require complex medication regimens. The positive impact of pharmacists on improving diabetes management or its co-morbidities has been recognised worldwide. This study aimed to characterise drug-related problems among diabetic patients in Hong Kong and their clinical significance, and to explore the role of pharmacists in the multidisciplinary diabetes management team by evaluating the outcome of their clinical interventions. METHODS: An observational study was conducted at the Diabetes Clinic of a public hospital in Hong Kong from October 2012 to March 2014...
March 17, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28302636/pharmacist-provided-medicines-reconciliation-within-24%C3%A2-hours-of-admission-and-on-discharge-a-randomised-controlled-pilot-study
#11
Brit Cadman, David Wright, Amanda Bale, Garry Barton, James Desborough, Eman A Hammad, Richard Holland, Helen Howe, Ian Nunney, Lisa Irvine
BACKGROUND: The UK government currently recommends that all patients receive medicines reconciliation (MR) from a member of the pharmacy team within 24 hours of admission and subsequent discharge. The cost-effectiveness of this intervention is unknown. A pilot study to inform the design of a future randomised controlled trial to determine effectiveness and cost-effectiveness of a pharmacist-delivered service was undertaken. METHOD: Patients were recruited 7 days a week from 5 adult medical wards in 1 hospital over a 9 month period and randomised using an automated system to intervention (MR within 24 hours of admission and at discharge) or usual care which may include MR (control)...
March 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28293768/the-utility-of-a-medical-admissions-pharmacist-in-a-hospital-in-australia
#12
Sally B Marotti, Rachael May Theng Cheh, Anne Ponniah, Helen Phuong
Background Medication-related hospital admissions in Australia have previously been estimated to account for approximately 3% of all hospital admissions, with hospital entry points being a point of vulnerability. The timely medication review and reconciliation by a pharmacist at the early stage of an admission for patients admitted to the Acute Medical Unit (AMU) would be beneficial. Setting The Emergency Department (ED) and AMU in a 300 bed tertiary teaching hospital, in South Australia. Objective To investigate the impact of a Medical Admissions (MA) pharmacist on the proportion of AMU patients who receive a complete and accurate medication history by a pharmacist prior to admission and within 4 h of presentation...
March 15, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28292507/opioid-exit-plan-a-pharmacist-s-role-in-managing-acute-postoperative-pain
#13
Cheryl Genord, Timothy Frost, Deeb Eid
OBJECTIVES: The benefits of a pharmacist's involvement in medication reconciliation and discharge counseling are well documented in the literature as improving patient outcomes. In contrast, no studies have focused on the initiation of a pharmacist-led opioid exit plan (OEP) for acute postoperative pain management. This paper summarizes a pharmacist-led OEP practice model and the potential role that pharmacists and student pharmacists can have at the point of admission, during postoperative recovery, and on discharge in acute pain management patients...
March 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28282304/the-digital-drag-and-drop-pillbox-design-and-feasibility-of-a-skill-based-education-model-to-improve-medication-management
#14
Bradi B Granger, Susan C Locke, Margaret Bowers, Tenita Sawyer, Howard Shang, Amy P Abernethy, Richard A Bloomfield, Catherine L Gilliss
OBJECTIVE: We present the design and feasibility testing for the "Digital Drag and Drop Pillbox" (D-3 Pillbox), a skill-based educational approach that engages patients and providers, measures performance, and generates reports of medication management skills. METHODS: A single-cohort convenience sample of patients hospitalized with heart failure was taught pill management skills using a tablet-based D-3 Pillbox. Medication reconciliation was conducted, and aptitude, performance (% completed), accuracy (% correct), and feasibility were measured...
March 9, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28280075/improving-reconciliation-following-medical-injury-a-qualitative-study-of-responses-to-patient-safety-incidents-in-new-zealand
#15
Jennifer Moore, Michelle M Mello
BACKGROUND: Despite the investment in exploring patient-centred alternatives to medical malpractice in New Zealand (NZ), the UK and the USA, patients' experiences with these processes are not well understood. We sought to explore factors that facilitate and impede reconciliation following patient safety incidents and identify recommendations for strengthening institution-led alternatives to malpractice litigation. METHODS: We conducted semistructured interviews with 62 patients injured by healthcare in NZ, administrators of 12 public hospitals, 5 lawyers specialising in Accident Compensation Corporation (ACC) claims and 3 ACC staff...
March 9, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28278290/exosomes-are-released-by-bystander-cells-exposed-to-radiation-induced-biophoton-signals-reconciling-the-mechanisms-mediating-the-bystander-effect
#16
Michelle Le, Cristian Fernandez-Palomo, Fiona E McNeill, Colin B Seymour, Andrew J Rainbow, Carmel E Mothersill
OBJECTIVE: The objective of our study was to explore a possible molecular mechanism by which ultraviolet (UV) biophotons could elicit bystander responses in reporter cells and resolve the problem of seemingly mutually exclusive mechanisms of a physical UV signal & a soluble factor-mediated bystander signal. METHODS: The human colon carcinoma cell line, HCT116 p53 +/+, was directly irradiated with 0.5 Gy tritium beta particles to induce ultraviolet biophoton emission...
2017: PloS One
https://www.readbyqxmd.com/read/28271120/code-status-reconciliation-to-improve-identification-and-documentation-of-code-status-in-electronic-health-records
#17
Viral G Jain, Peter J Greco, David C Kaelber
BACKGROUND: Code status (CS) of a patient (part of their end-of-life wishes) can be critical information in healthcare delivery, which can change over time, especially at transitions of care. Although electronic health record (EHR) tools exist for medication reconciliation across transitions of care, much less attention is given to CS, and standard EHR tools have not been implemented for CS reconciliation (CSR). Lack of CSR creates significant potential patient safety and quality of life issues...
March 8, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28266339/medication-reconciliation-a-learning-process-for-reduce-the-risk-of-medication-errors
#18
Gilles Berrut
No abstract text is available yet for this article.
March 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28256931/barriers-to-discharge-from-inpatient-rehabilitation-a-teamwork-approach
#19
Lisanne Catherine Cruz, Jeffrey S Fine, Subhadra Nori
Purpose In order to prevent adverse events during the discharge process, coordinating appropriate community resources, medication reconciliation, and patient education needs to be implemented before the patient leaves the hospital. This coordination requires communication and effective teamwork amongst staff members. In order to address these concerns, the purpose of this paper is to incorporate the TeamSTEPPS principles to develop a discharge plan that would best meet the needs of the patients as they return to the community...
March 13, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28224259/a-black-theological-response-to-race-based-medicine-reconciliation-in-minority-communities
#20
Kirk A Johnson
The harm race-based medicine inflicts on minority bodies through race-based experimentation and the false solutions a race-based drug ensues within minority communities provokes concern. Such areas analyze the minority patient in a physical proxy. Though the mind and body are important entities, we cannot forget about the spirit. Healing is not just a physical practice; it includes spiritual practice. Efficient medicine includes the holistic elements of the mind, body, and spirit. Therefore, the spiritual discipline of black theology can be used as a tool to mend the harms of race-based medicine...
June 2017: Journal of Religion and Health
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