polimedicado

OBJECTIVES: To assess the effectiveness of a pharmacist-led systematic review of medications on: potentially inappropriate medications (PIM), health outcomes and costs. DESIGN: Prospective, open, controlled and cluster-randomized clinical trial. SETTING: Six primary care clinics from Balearic Islands. PARTICIPANTS: Forty-two clusters (21 per group), and 549 patients aged ≥65 years and ≥5 chronic medications were included; of which 277 were allocated to Intervention Group (IG) and 272 to Control Group (CG)...

OBJECTIVE: Polypharmacy and potentially inappropriate medications (that  is, those associated with an unfavorable risk-benefit ratio) are common concerns in the context of elderly patients treated in primary care as they may increase the risk of morbidity and mortality, as well as  healthcare costs. Several studies have assessed the impact of pharmacist- led systematic reviews with respect to prescription appropriateness, health outcomes and/or costs. However, no cluster-randomized controlled  trial has been identified that provides an overall assessment of these  variables...

Frail elders have higher risk of falls, with associated morbidity and mortality. Our objective was to reduce the percentage of falls in frail elders after a multifactorial and systemic intervention. Design: before-after quasi-experimental study, with own individual as control. Scope: patient’s living place, in the metropolitan area of ​​Buenos Aires city. Recruitment period: 01/10/2017-31/04/2018. Baseline assessment and 3-month follow-up. Inclusion criteria: ≥65 years with criteria of frailty according to the treating physician...

OBJECTIVE: to identify and summarize studies examining both drug-drug interactions (DDI) and adverse drug reactions (ADR) in older adults polymedicated. METHODS: an integrative review of studies published from January 2008 to December 2013, according to inclusion and exclusion criteria, in MEDLINE and EMBASE electronic databases were performed. RESULTS: forty-seven full-text studies including 14,624,492 older adults (≥ 60 years) were analyzed: 24 (51...