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https://www.readbyqxmd.com/read/28449183/noninferiority-trial-investigating-the-efficacy-of-a-nonantibiotic-intramammary-therapy-in-the-treatment-of-mild-to-moderate-clinical-mastitis-in-dairy-cows-with-longer-lasting-udder-diseases
#1
M Ziesch, N Wente, Y Zhang, W Zaremba, S Engl, V Krömker
A nonblinded, positively controlled, noninferiority trial was conducted to evaluate the efficacy of an alternative, nonantibiotic therapy with Masti Veyxym(®) to reduce ineffective antibiotic usage in the treatment of nonsevere clinical mastitis (CM) in cows with longer lasting udder diseases. The solely intramammary treatment with Masti Veyxym(®) (three applications, 12 hr apart) and the combined treatment with Masti Veyxym(®) and antibiotics as usual on the farm according to label of the respective product were compared with the reference treatment of solely antibiotic therapy...
April 27, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28442176/mastitis-outcomes-on-pre-ovulatory-follicle-diameter-estradiol-concentrations-subsequent-luteal-profiles-and-conception-rate-in-buffaloes
#2
Mohamed Mohsen Mansour, Moustafa M Zeitoun, Fekry M Hussein
The objectives of this study was to investigate the outcome of mastitis, in its clinical or subclinical forms, on the mean diameter of pre-ovulatory follicle (POF), plasma estradiol concentration on the day of estrus, subsequent luteal profile and subsequent conception rate in buffaloes. Sixty dairy buffalo (Bubalus bubalus) conducted in this study were divided into three groups {healthy (H), n=20; subclinical mastitis (SCM), n=18; and clinical mastitis (CM), n=22}. Ultrasonography of ovaries revealed that mean diameter of POF was larger (P<0...
April 14, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28442140/cystic-neutrophilic-granulomatous-mastitis-associated-with-corynebacterium-including-corynebacterium-kroppenstedtii
#3
Kate J Johnstone, Jennifer Robson, Sarah G Cherian, Jenny Wan Sai Cheong, Kris Kerr, Judith F Bligh
Granulomatous (lobular) mastitis is a rare inflammatory breast disease affecting parous reproductive-aged women. Once considered idiopathic, there is growing evidence of an association with corynebacteria infection, especially in the setting of a distinct histological pattern termed cystic neutrophilic granulomatous mastitis (CNGM). We describe 15 cases with histological features either confirming (n = 12) or suggesting (n = 3) CNGM, and concurrent microbiological evidence of Corynebacterium species. The organism was detected by culture or 16S rRNA gene sequencing of specimens obtained at surgery or fine needle aspiration...
April 22, 2017: Pathology
https://www.readbyqxmd.com/read/28438941/new-macrolide-lincosamide-streptogramin-b-resistance-gene-erm-48-on-the-novel-plasmid-pjw2311-in-staphylococcus-xylosus
#4
Juliette R K Wipf, Matthew C Riley, Stephen A Kania, David A Bemis, Sabrina Andreis, Sybille Schwendener, Vincent Perreten
Whole-genome sequencing of Staphylococcus xylosus strain JW2311 from bovine mastitis milk identified the novel 49.3 kb macrolide-lincosamide-streptogramin B (MLSB) resistance plasmid pJW2311. It contained the macrolide resistance gene mph(C), the macrolide-streptogramin B resistance gene msr(A), and the new MLSB resistance gene erm (48) and could be transformed into S. aureus by electroporation. Functionality of erm (48) was demonstrated by cloning and expression in S. aureus.
April 24, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28438095/arcobacter-an-emerging-food-borne-zoonotic-pathogen-its-public-health-concerns-and-advances-in-diagnosis-and-control-a-comprehensive-review
#5
Thadiyam Puram Ramees, Kuldeep Dhama, Kumaragurubaran Karthik, Ramswaroop Singh Rathore, Ashok Kumar, Mani Saminathan, Ruchi Tiwari, Yashpal Singh Malik, Raj Kumar Singh
Arcobacter has emerged as an important food-borne zoonotic pathogen, causing sometimes serious infections in humans and animals. Newer species of Arcobacter are being incessantly emerging (presently 25 species have been identified) with novel information on the evolutionary mechanisms and genetic diversity among different Arcobacter species. These have been reported from chickens, domestic animals (cattle, pigs, sheep, horses, dogs), reptiles (lizards, snakes and chelonians), meat (poultry, pork, goat, lamb, beef, rabbit), vegetables and from humans in different countries...
April 25, 2017: Veterinary Quarterly
https://www.readbyqxmd.com/read/28436180/control-mechanisms-for-producing-antimicrobial-factors-in-ruminant-mammary-gland
#6
REVIEW
Naoki Isobe
Mastitis, a symptom of inflammation in mammary tissue by infection with various kinds of bacteria, causes huge economic losses in the milk industry. One of the popular methods for treatment of mastitis is antibiotics, although this prohibits milk shipping and sometimes causes resistant microbes. Therefore, a new strategy to treat mastitis without antibiotics is eagerly required around the world. Antimicrobial factors belong to innate immunity and can start their function extremely early after bacterial stimulation...
April 24, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28435202/phenotypic-and-genotypic-characterization-of-methicillin-resistant-staphylococcus-aureus-from-bovine-mastitis
#7
S Hamid, Mohd Altaf Bhat, Irfan Ahmad Mir, Anil Taku, Gulzar Ahmad Badroo, Salik Nazki, Andleeb Malik
AIM: This study was conducted to determine the occurrence of methicillin-sensitive and Staphylococcus aureus (MSSA) methicillin-resistant S. aureus (MRSA) from bovine mastitis and to characterize them with respect to antibiotic resistance gene mecA. MATERIALS AND METHODS: A total of 160 mastitic milk samples were screened for the presence of S. aureus. The presumptive positive isolates were confirmed using nuc and 23S rRNA gene-based polymerase chain reaction. All the confirmed isolates were subjected to in vitro antibiogram using a number of antibiotics...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28435201/association-of-claw-disorders-with-subclinical-intramammary-infections-in-egyptian-dairy-cows
#8
Walid Refaai, Medhat Gad, Yasser Mahmmod
AIM: Bovine mastitis and lameness are the most common production diseases affecting dairy farms worldwide resulting in huge economic impact and impaired animal welfare. The objective of this field study was to investigate the association of infectious and non-infectious claw disorders with the occurrence of subclinical intramammary infections (IMIs) diagnosed by California mastitis test (CMT) in dairy cows under Egyptian conditions. MATERIALS AND METHODS: A total of 43 dairy cows were included in this field study...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28435193/can-methicillin-resistant-staphylococcus-aureus-prevalence-from-dairy-cows-in-india-act-as-potential-risk-for-community-associated-infections-a-review
#9
REVIEW
Sathish Gopal, Kurunchi C Divya
Methicillin-resistant Staphylococcus aureus (MRSA) is classified as hospital associated (HA), community associated (CA), livestock associated (LA) and is a global concern. Developing countries, like India, are densely populated country challenging for public hygiene practices. HA-MRSA is comfortably recorded in India, and CA-MRSA is also reported as increasing one. CA-MRSA is serious disease which affects the community as endemic. MRSA is one among major mastitis-causing organisms in India as LA-MRSA. There were reports for transmission of MRSA as community between milk handlers and cow in global perspective...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28434747/bivariate-threshold-models-for-genetic-evaluation-of-susceptibility-to-and-ability-to-recover-from-mastitis-in-danish-holstein-cows
#10
B G Welderufael, L L G Janss, D J de Koning, L P Sørensen, P Løvendahl, W F Fikse
Mastitis in dairy cows is an unavoidable problem and genetic variation in recovery from mastitis, in addition to susceptibility, is therefore of interest. Genetic parameters for susceptibility to and recovery from mastitis were estimated for Danish Holstein-Friesian cows using data from automatic milking systems equipped with online somatic cell count measuring units. The somatic cell count measurements were converted to elevated mastitis risk, a continuous variable [on a (0-1) scale] indicating the risk of mastitis...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434738/relationships-among-superantigen-toxin-gene-profiles-genotypes-and-pathogenic-characteristics-of-staphylococcus-aureus-isolates-from-bovine-mastitis
#11
Dong Wang, Limei Zhang, Changfu Yong, Mingliang Shen, Tariq Ali, Muhammad Shahid, Kun Han, Xuezhang Zhou, Bo Han
Staphylococcus aureus is one of the major etiological agents of bovine mastitis, harboring a wide variety of staphylococcal superantigen (SAg) toxin genes. The SAg toxin genes are reported to be closely associated with the pathogenicity of the Staph. aureus causing the bovine mastitis. This study was conducted to investigate SAg toxin gene profiles and to assess the relationships among SAg toxin genes, genotypes of Staph. aureus, and their pathogenic properties. A total of 327 quarter milk samples were collected from bovine mastitis cases for isolation and identification of pathogens...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434736/incidence-of-clinical-mastitis-and-distribution-of-pathogens-on-large-chinese-dairy-farms
#12
Jian Gao, Herman W Barkema, Limei Zhang, Gang Liu, Zhaoju Deng, Lingjie Cai, Ruixue Shan, Shiyao Zhang, Jiaqi Zou, John P Kastelic, Bo Han
Knowledge of the incidence of clinical mastitis (CM) and the distribution of pathogens involved is essential for development of prevention and control programs as well as treatment protocols. No country-wide study on the incidence of CM and the distribution of pathogens involved has been conducted in China. Core objectives of this study were, therefore, to determine the cumulative incidence of CM and the distribution of pathogens causing CM on large Chinese (>500 cows) dairy farms. In addition, associations between the distribution of CM pathogens and bedding materials and seasonal factors were also investigated...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28428772/molecular-characterization-of-staphylococcus-aureus-isolated-from-bovine-mastitis-and-close-human-contacts-in-south-african-dairy-herds-genetic-diversity-and-inter-species-host-transmission
#13
Tracy Schmidt, Marleen M Kock, Marthie M Ehlers
Staphylococcus aureus is one of the most common etiological agents of contagious bovine mastitis worldwide. The purpose of this study was to genetically characterize a collection of S. aureus isolates (bovine = 146, human = 12) recovered from cases of bovine mastitis and nasal swabs of close human contacts in the dairy environment. Isolates were screened for a combination of clinically significant antimicrobial and virulence gene markers whilst the molecular epidemiology of these isolates and possible inter-species host transmission was investigated using a combination of genotyping techniques...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28428315/improved-high-quality-draft-genome-sequence-and-annotation-of-burkholderia-contaminans-lmg-23361-t
#14
Ji Young Jung, Youngbeom Ahn, Ohgew Kweon, John J LiPuma, David Hussong, Bernard S Marasa, Carl E Cerniglia
Burkholderia contaminans LMG 23361 is the type strain of the species isolated from the milk of a dairy sheep with mastitis. Some pharmaceutical products contain disinfectants such as benzalkonium chloride (BZK) and previously we reported that B. contaminans LMG 23361(T) possesses the ability to inactivate BZK with high biodegradation rates. Here, we report an improved high-quality draft genome sequence of this strain.
April 20, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28428133/epidemiological-study-of-common-diseases-and-their-risk-factors-in-camels-in-south-punjab-pakistan
#15
Aneela Zameer Durrani, Zubair Bashir, Imran Rasheed, Noor-Ul-Ain Sarwar
Bacteriological study of mastitis along with common blood protozoan diseases were studied in dromedary camels in Cholistan, Dera Ismail Khan and Rahim Yar Khan districts in South Punjab, Pakistan. For this purpose 300 camels were sampled randomly at different common grazing and watering point. For study of blood parasites clinically suspected and apparently healthy camels, 150 each, were sampled. An overall prevalence of 15%and 5% was recorded for trypanosomiasis and Anaplasmosis respectively. Trypanosoma evansi was identified with 280 bp product on polymerase chain reaction test...
April 17, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28427433/prevalence-of-subclinical-mastitis-in-finnish-dairy-cows-changes-during-recent-decades-and-impact-of-cow-and-herd-factors
#16
Heidi Hiitiö, Johanna Vakkamäki, Heli Simojoki, Tiina Autio, Jouni Junnila, Sinikka Pelkonen, Satu Pyörälä
BACKGROUND: The dairy industry has undergone substantial structural changes as intensive farming has developed during recent decades. Mastitis continues to be the most common production disease of dairy cows. Nationwide surveys of mastitis prevalence are useful in monitoring udder health of dairy herds and to study the impact of structural changes on the dairy industry. This survey on bovine subclinical mastitis was the first based on cow composite milk somatic cell count (SCC) data from the Finnish national health monitoring and milk recording database...
April 20, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28424255/analysis-of-milk-from-mothers-who-delivered-prematurely-reveals-few-changes-in-proteases-and-protease-inhibitors-across-gestational-age-at-birth-and-infant-postnatal-age
#17
Veronique Demers-Mathieu, Søren Drud Nielsen, Mark A Underwood, Robyn Borghese, David C Dallas
Background: Peptidomics research has demonstrated that protease activity is higher in breast milk from preterm-delivering mothers than from term-delivering mothers. However, to our knowledge, the effect of the degree of prematurity and postnatal age on proteases and protease inhibitors in human milk remains unknown.Objective: We aimed to determine the change of proteases and protease inhibitors in milk from mothers who delivered prematurely across gestational age (GA) and postnatal age.Methods: Milk samples were collected from 18 mothers aged 26-40 y who delivered preterm infants and who lacked mastitis...
April 19, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28418794/microbial-diversity-in-milk-of-women-with-mastitis-potential-role-of-coagulase-negative-staphylococci-viridans-group-streptococci-and-corynebacteria
#18
Pilar Mediano, Leonides Fernández, Esther Jiménez, Rebeca Arroyo, Irene Espinosa-Martos, Juan M Rodríguez, María Marín
BACKGROUND: Lactational mastitis constitutes a significant cause of premature weaning. However, its etiology, linked to the presence of pathogenic microorganisms, has been scarcely reported. Research aim: The aim of this study was to describe the microbial diversity in milk samples from women suffering from lactational mastitis and to identify more accurately a collection of isolates belonging to coagulase-negative staphylococci, streptococci, and coryneform bacteria. METHODS: This is a cross-sectional descriptive one-group study...
May 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28418698/incidence-and-risk-factors-of-mastitis-in-shiraz-iran-results-of-a-cohort-study
#19
Mahnaz Zarshenas, Yun Zhao, Shahnaz Poorarian, Colin W Binns, Jane A Scott
BACKGROUND: Approximately one in five Western women who breastfeed are likely to experience acute mastitis. This study investigated the incidence and risk factors of acute mastitis in a cohort of Iranian women. SUBJECTS AND METHODS: Subjects were 672 participants of the Shiraz Infant Feeding Study conducted between June 2014 and March 2015. Mothers were recruited from the maternity ward and followed up at 1, 3, 4, and 6 months postpartum to obtain information on their breastfeeding practices and experiences...
April 18, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28415707/luteolin-reduces-inflammation-in-staphylococcus-aureus-induced-mastitis-by-inhibiting-nf-kb-activation-and-mmps-expression
#20
Ying-Fang Guo, Nian-Nian Xu, Weijing Sun, Yifan Zhao, Cheng-Ye Li, Meng-Yao Guo
Mastitis is a serious and prevalent disease caused by infection by pathogens such as Staphylococcus aureus. We evaluated the anti-inflammatory effects and mechanism of luteolin, a natural flavonoid with a wide range of pharmacological activities, in a mouse model of S. aureus mastitis. We also treated cultured mouse mammary epithelial cells (mMECs) with S. aureus and luteolin. Histopathological changes were examined by H&E staining and the levels of inflammatory cytokine proteins were analyzed using ELISAs...
March 10, 2017: Oncotarget
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