Yuqing E Chen, Mingui Fu, Jifeng Zhang, Xiaojun Zhu, Yiming Lin, Mukaila A Akinbami, Qing Song
Insulin resistance syndrome (also called syndrome X) includes obesity, diabetes, hypertension, and dyslipidemia and is a complex phenotype of metabolic abnormalities. The disorder poses a major public health problem by predisposing individuals to coronary heart disease and stroke, the leading causes of mortality in Western countries. Given that hypertension, diabetes, dyslipidemia, and obesity exhibit a substantial heritable component, it is postulated that certain genes may predispose some individuals to this cluster of cardiovascular risk factors...
2003: Vitamins and Hormones