Myriam Taga, Yoon N G Hong, Charalambos C Charalambous, Sharmila Raju, Leticia Hayes, Jing Lin, Yian Zhang, Yongzhao Shao, Michael Houston, Yingchun Zhang, Pietro Mazzoni, Jinsook Roh, Heidi M Schambra
UNLABELLED: After corticospinal tract (CST) stroke, several motor deficits in the upper extremity (UE) emerge, including diminished muscle strength, motor control, and muscle individuation. Both the ipsilesional CST and contralesional corticoreticulospinal tract (CReST) innervate the paretic UE and may have different innervation patterns for the proximal and distal UE segments. These patterns may underpin distinct pathway relationships to separable motor behaviors. In this cross-sectional study of 15 chronic stroke patients and 28 healthy subjects, we examined two key questions: (1) whether segmental motor behaviors differentially relate to ipsilesional CST and contralesional CReST projection strengths, and (2) whether motor behaviors segmentally differ in the paretic UE...
April 14, 2024: bioRxiv