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https://www.readbyqxmd.com/read/29045971/-technical-improvement-in-retroperitoneal-laparoscopic-living-donor-nephrectomy-report-of-193-cases
#1
L Zhao, L L Ma, H X Zhang, X F Hou, L Liu, Y Fu, Y G Kou, Y M Song
OBJECTIVE: To summarize our experience of retroperitoneal laparoscopic living donor nephrectomy, our continuous technical improvements and refinement of this skill and standardization of each procedure of this operation. METHODS: Having approved by hospital ethical committee and local government administration, a total of 193 living donors underwent retroperitoneal laparoscopic living donor nephrectomy from Dec.2003 to Feb. 2016 in our department. Under general anaesthesia, the operation was performed through 3 lumbar ports...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29044338/nutritional-profile-of-hemodialysis-patients-concerning-treatment-time
#2
Livia de Almeida Alvarenga, Bárbara Danelon Andrade, Michelle Andrade Moreira, Roberto de Paula Nascimento, Isabela Dariú Macedo, Aline Silva de Aguiar
INTRODUCTION: The mortality of the population with chronic kidney disease (CKD) on hemodialysis (HD) is very high and the protein-energy malnutrition stands out as one of the most common consequences in relation to this condition. OBJECTIVE: To evaluate the association between time of hemodialysis and nutritional parameters of patients. METHODS: It is a cross-sectional study with secondary data, developed of the University Hospital of the Federal University of Juiz de Fora (HU/UFJF)...
July 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29042386/effectiveness-of-an-electronic-patient-centred-self-management-tool-for-gout-sufferers-a-cluster-randomised-controlled-trail-protocol
#3
Richard O Day, Lauren J Frensham, Amy D Nguyen, Melissa T Baysari, Eindra Aung, Annie Y S Lau, Nicholas Zwar, Jennifer Reath, Tracey Laba, Ling Li, Andrew McLachlan, William B Runciman, Rachelle Buchbinder, Robyn Clay-Williams, Enrico Coiera, Jeffrey Braithwaite, H Patrick McNeil, David J Hunter, Kevin J Pile, Ian Portek, Kenneth Mapson WIlliams, Johanna I Westbrook
INTRODUCTION: Gout is increasing despite effective therapies to lower serum urate concentrations to 0.36 mmol/L or less, which, if sustained, significantly reduces acute attacks of gout. Adherence to urate-lowering therapy (ULT) is poor, with rates of less than 50% 1 year after initiation of ULT. Attempts to increase adherence in gout patients have been disappointing. We aim to evaluate the effectiveness of use of a personal, self-management, 'smartphone' application (app) to achieve target serum urate concentrations in people with gout...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29041781/nursing-students-perceptions-of-soft-skills-training-in-ghana
#4
Luke Laari, Barbara M Dube
BACKGROUND: The quality of nursing care rendered today is markedly reducing and the amount of time spent with patients listening to and explaining issues concerning their conditions is gradually diminishing. The therapeutic touch and the listening ear of the nurse are no longer accessible to the patient. Understanding what non-technical skills are and their relevance for healthcare practitioners has become a new area of consideration. Although recent literature has highlighted the necessity of introducing soft skills training and assessment within medical education, nursing education is yet to fully embrace this skills training...
September 22, 2017: Curationis
https://www.readbyqxmd.com/read/29040066/evaluation-of-oral-multi-herbal-preparation-of-dashmoolarishta-on-mice-model-of-osteoarthritis
#5
Yashashri C Shetty, Santosh Godbharle, Smita Brahma, Sweta Salgaonkar, Nirmala N Rege
BACKGROUND: Osteoarthritis (OA) is a chronic progressive disease commonly affecting the hip and knee joints. Although synthetic drugs are available and afford symptomatic relief, their side effects pose limitations to their continuous use. So, this research was focused on extracting drugs from indigenous medicinal plants that could have a beneficial effect on osteoarthritis. Dashmoolarishta is one such preparation whose effects have never been studied in comparison with recent drugs like hyaluronic acid (HA), hence this particular study was undertaken...
October 17, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/29040058/recommendations-for-laboratory-containment-and-management-of-gene-drive-systems-in-arthropods
#6
Mark Q Benedict, Austin Burt, Margareth L Capurro, Paul De Barro, Alfred M Handler, Keith R Hayes, John M Marshall, Walter J Tabachnick, Zach N Adelman
Versatile molecular tools for creating driving transgenes and other invasive genetic factors present regulatory, ethical, and environmental challenges that should be addressed to ensure their safe use. In this article, we discuss driving transgenes and invasive genetic factors that can potentially spread after their introduction into a small proportion of individuals in a population. The potential of invasive genetic factors to increase their number in natural populations presents challenges that require additional safety measures not provided by previous recommendations regarding accidental release of arthropods...
October 17, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29039325/comparative-role-of-pregabalin-and-carbamazepine-regarding-efficacy-in-painful-diabetic-neuropathy
#7
Raana Mahmood, Itrat Jawed, M Irfan Khan, Iffat Mahmood, Talat Tariq, Arfa Kamil, Faiza Z Sayeed, Bushra Z Sayeed
Neuropathic pain is the most severe and resistant type of pain which has impact on quality of life and behaviour; it most commonly occurs at night causing disturbed sleep. Diabetes mellitus is a common cause of painful neuropathy. In this study, we are comparing the effectiveness of old treatment Carbamazepine with Pregabalin in painful diabetic neuropathy. The study was an open-label trial conducted in Diabetic Clinic of Medical Unit-III, Jinnah Post-graduate Medical Center, Karachi. The duration of the study was 90 days, from December 2010 to March 2011...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29039321/assessment-of-thyroid-hormone-levels-and-thyroid-disorders-a-case-study-from-gujranwala-pakistan
#8
Narjis Naz, Shakera Khatoon Rizvi, Zubi Sadiq
This case study is conducted to investigate the thyroid hormone levels and relevant disorders including evaluation of dietary conditions in the rural area of Gujranwala and its surrounding districts. Thyroid disorders are clinically prevalent and their manifestation differs considerably with geographical variations. A randomized study of 177 subjects was carried out, with a questionnaire about their dietary habits/life style and acquisition of blood samples for thyroid hormone level assessment using radioimmunoassay technique...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29039153/postoperative-analgesia-after-arthroscopic-shoulder-surgery-a-comparison-between-single-shot-interscalene-block-and-single-shot-supraclavicular-block
#9
Ahmet Kemalettin Koltka, Mehmet Büget, Emre Sertaç Bingül, Ali Erşen, Süleyman Küçükay, Ata Can Atalar, Mert Şentürk
OBJECTIVES: In arthroscopic rotator cuff surgery for postoperative analgesia opioids, nonsteroid analgesics, and local anesthetics can be used. This study aimed to compare the effectiveness, additional analgesic requirements, patients satisfaction, and complications of single-shot interscalene and supraclavicular blocks. METHODS: After obtaining the ethics committee's approval and informed consent, 50 ASA I-II patients were randomized to either the interscalene (GISB) or supraclavicular (GSCB) group...
July 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29038184/optimising-the-quality-of-antibiotic-prescribing-in-out-of-hours-primary-care-in-belgium-a-study-protocol-for-an-action-research-project
#10
Annelies Colliers, Samuel Coenen, Hilde Philips, Roy Remmen, Sibyl Anthierens
INTRODUCTION: Antimicrobial resistance is a major public health threat driven by inappropriate antibiotic use, mainly in general practice and for respiratory tract infections. In Belgium, the quality of general practitioners' (GPs) antibiotic prescribing is low. To improve antibiotic use, we need a better understanding of this quality problem and corresponding interventions. A general practitioners cooperative (GPC) for out-of-hours (OOH) care presents a unique opportunity to reach a large group of GPs and work on quality improvement...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29038175/predictability-of-recurrence-using-immunohistochemistry-to-delineate-surgical-margins-in-mucosal-head-and-neck-squamous-cell-carcinoma-prism-hnscc-study-protocol-for-a-prospective-observational-and-bilateral-study-in-australia-and-india
#11
Sheela Joseph, Rajinikanth Janakiraman, Geeta Chacko, Rama Jayaraj, Mahiban Thomas, Meera Thomas, Sramana Mukhopadhyay
OBJECTIVES: Treatment failure and poor 5-year survival in mucosal head and neck squamous cell carcinoma (HNSCC) has remained unchanged for decades mainly due to advanced stage of presentation and high rates of recurrence. Incomplete surgical removal of the tumour, attributed to lack of reliable methods to delineate the surgical margins, is a major cause of disease recurrence. The predictability of recurrence using immunohistochemistry (IHC) to delineate surgical margins (PRISM) in mucosal HNSCC study aims to redefine margin status by identifying the true extent of the tumour at the molecular level by performing IHC with molecular markers, eukaryotic initiation factor, eIF4Eand tumour suppressor gene, p53, on the surgical margins and test the use of Lugol's iodine and fluorescence visualisation prior to the wide local excision...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29037484/australian-midwives-views-and-experiences-of-practice-and-politics-related-to-water-immersion-for-labour-and-birth-a-web-based-survey
#12
Megan Cooper, Jane Warland, Helen McCutcheon
BACKGROUND: There is little published research that has examined practitioners' views and experiences of pain relieving measures commonly used during labour and birth, particularly for non-pharmacological measures such as water immersion. Furthermore, there is minimal published research examining the process of policy and guideline development, that is, the translation of published research to usable practice guidance. AIMS: The aims of phase three of a larger study were to explore midwives knowledge, experiences and support for the option of water immersion for labour and birth in practice and their involvement, if any, in development of policy and guidelines pertaining to the option...
October 13, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29032585/infection-surveillance-in-pediatric-hematopoietic-stem-cell-transplantation-recipients
#13
Daniela Caldas Teixeira, Lilian Martins Oliveira Diniz, Paulo Henrique Orlandi Mourão, Fabiana Maria Kakehashi, Antonio Vaz de Macedo, Helena Duani, Wanessa Trindade Clemente, Karla Emília de Sá Rodrigues, Roberta Maia de Castro Romanelli
OBJECTIVE: Describe the profile of reported Healthcare-Associated Infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center. METHODS: Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance performed daily by professionals. This study was approved by the Institutional Research Ethics Committee...
October 15, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/29027671/ethical-challenges-of-personal-disclosure-in-gaining-entry-with-religious-congregations
#14
Nathan R Todd
This is a story about learning how to navigate my social identities as a non-religious gay man attempting to conduct data-based consultation with a religious congregation. Beyond my own growth in knowing myself better, this story speaks to the larger ethical challenge of how we build trust in community relationships, and in particular how much of our personal selves we need to disclose in the process of an individual or group deciding to work with us. Individuals and groups make decisions to work with us based on who they perceive us to be; thus, what is our ethical obligation to disclose aspects of who we are to promote full informed consent? To illustrate this ethical challenge of personal disclosure, I tell the story of discussions I had with three different religious leaders and a congregational committee about potentially working together...
October 13, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/29026498/a-case-control-study-of-comparison-of-plasma-levels-of-matrix-metalloproteinase-9-in-inhaled-opium-addicts-and-clinically-healthy-persons
#15
Maryam Amizadeh, Shahryar Dabiri, Armin Javedan, Ali Eftekharian, Aliasghar Arabi-Mianroodi
BACKGROUND: Metalloproteinase-9 exists in the basement membrane of normal tissues and is a major factor in cancer invasion and lymphatic metastasis. Smoking has been reported to increase the metalloproteinase level, but the role of opium consumption in metalloproteinase level has not yet been examined. The current research intended to examine the impacts of opium consumption on the serum levels of metalloproteinase. METHODS: This case-control research was conducted in Kerman (in the southeast of Iran), after getting medical approve by the ethics committee...
January 2017: Addiction & Health
https://www.readbyqxmd.com/read/29026464/evaluation-of-doppler-ultrasonography-in-the-diagnosis-of-transjugular-intrahepatic-portosystemic-shunt-dysfunction-a-prospective-study
#16
Charlotte Nicolas, Amélie Le Gouge, Louis d'Alteroche, Jean Ayoub, Monica Georgescu, Vincent Vidal, Denis Castaing, Jean-Pierre Cercueil, Patrick Chevallier, Jérôme Roumy, Hervé Trillaud, Louis Boyer, Vincent Le Pennec, Christophe Perret, Bruno Giraudeau, Jean-Marc Perarnau, Stic-Tips Group
AIM: To prospectively evaluate the performance of Doppler-ultrasonography (US) for the detection of transjugular intrahepatic portosystemic shunt (TIPS) dysfunction within a multicenter cohort of cirrhotic patients. METHODS: This study was conducted in 10 french teaching hospitals. After TIPS insertion, angiography and liver Doppler-US were carried out every six months to detect dysfunction (defined by a portosystemic gradient ≥ 12 mmHg and/or a stent stenosis ≥ 50%)...
September 28, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/29025851/investigating-bordetella-pertussis-colonisation-and-immunity-protocol-for-an-inpatient-controlled-human-infection-model
#17
Hans de Graaf, Diane Gbesemete, Andrew R Gorringe, Dimitri A Diavatopoulos, Kent E Kester, Saul N Faust, Robert C Read
INTRODUCTION: We summarise an ethically approved protocol for the development of an experimental human challenge colonisation model. Globally Bordetella pertussis is one of the leading causes of vaccine-preventable death. Many countries have replaced whole cell vaccines with acellular vaccines over the last 20 years during which pertussis appears to be resurgent in a number of countries in the developed world that boast high immunisation coverage. The acellular vaccine provides relatively short-lived immunity and, in contrast to whole cell vaccines, may be less effective against colonisation and subsequent transmission...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025845/a-multicentre-randomised-controlled-trial-assessing-whether-mri-targeted-biopsy-is-non-inferior-to-standard-transrectal-ultrasound-guided-biopsy-for-the-diagnosis-of-clinically-significant-prostate-cancer-in-men-without-prior-biopsy-a-study-protocol
#18
Veeru Kasivisvanathan, Fatima Jichi, Laurence Klotz, Arnauld Villers, Samir S Taneja, Shonit Punwani, Alex Freeman, Mark Emberton, Caroline M Moore
INTRODUCTION: The classical pathway for the diagnosis of prostate cancer is transrectal ultrasound-guided (TRUS) biopsy of the prostate initiated on the basis of a raised prostate-specific antigen (PSA). An alternative pathway is to perform multi-parametricMRI (MPMRI) to localise cancer and to use this information to influence the decision for, and conduct of, a subsequent biopsy, known as an MPMRI-targeted biopsy. An MPMRI pathway has been shown to detect a similar or greater amount of clinically significant cancer as TRUS biopsy but has several advantages, including the potential to biopsy fewer men with fewer cores...
October 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025844/investigating-canadian-parents-hpv-vaccine-knowledge-attitudes-and-behaviour-a-study-protocol-for-a-longitudinal-national-online-survey
#19
Gilla K Shapiro, Samara Perez, Anila Naz, Ovidiu Tatar, Juliet R Guichon, Rhonda Amsel, Gregory D Zimet, Zeev Rosberger
INTRODUCTION: Human papillomavirus (HPV), a sexually transmitted infection, can cause anogenital warts and a number of cancers. To prevent morbidity and mortality, three vaccines have been licensed and are recommended by Canada's National Advisory Committee on Immunisation (for girls since 2007 and boys since 2012). Nevertheless, HPV vaccine coverage in Canada remains suboptimal in many regions. This study will be the first to concurrently examine the correlates of HPV vaccine decision-making in parents of school-aged girls and boys and evaluate changes in parental knowledge, attitudes and behaviours over time...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29025839/family-attitudes-actions-decisions-and-experiences-following-implementation-of-deemed-consent-and-the-human-transplantation-wales-act-2013-mixed-method-study-protocol
#20
Jane Noyes, Karen Morgan, Phillip Walton, Abigail Roberts, Leah Mclaughlin, Michael Stephens
INTRODUCTION: The Human Transplantation (Wales) Act 2013 (the Act) introduced a 'soft opt-out' system of organ donation on 1 December 2015. Citizens are encouraged to make their organ donation decision known during their lifetime. In order to work, the Act and media campaign need to create a context, whereby organ donation becomes the norm, and create a mechanism for people to behave as intended (formally register their decision; consider appointing a representative; convey their donation decision to their families and friends or do nothing-deemed consent)...
October 12, 2017: BMJ Open
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