Ao Bian, Fan Xiao, Xinyuan Kong, Xinlei Ji, Shulin Fang, Jiayue He, Qinyu Liu, Runqing Zhong, Shuqiao Yao, Qiang Luo, Xiang Wang
BACKGROUND: We aimed to develop a clinical predictive model based on the cognitive neuropsychological (CNP) theory and machine-learning to examine SSRI efficacy in the treatment of MDD. METHODS: Baseline assessments including clinical symptoms (HAMD, HAMA, BDI, and TEPS scores), negative biases (NEO-PI-R-N and NCPBQ scores), sociodemographic characteristics (social support and SES), and a 5-min eye-opening resting-state EEG were completed by 69 participants with first-episode major depressive disorder (MDD) and 36 healthy controls...
March 12, 2024: Journal of Affective Disorders