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Neuropsychological development

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https://www.readbyqxmd.com/read/28443616/effects-of-extended-cannabis-abstinence-on-cognitive-outcomes-in-cannabis-dependent-patients-with-schizophrenia-versus-non-psychiatric-controls
#1
Rachel A Rabin, Mera S Barr, Michelle S Goodman, Yarissa Herman, Konstantine K Zakzanis, Stephen J Kish, Michael Kiang, Gary Remington, Tony P George
Cross-sectional studies of the effects of cannabis on cognition in schizophrenia have produced mixed results. Heavy and persistent cannabis use in schizophrenia is a common clinical problem, and effects of controlled abstinence from cannabis in these patients have not been carefully evaluated. The present study sought to determine the effects of cannabis abstinence on cognition in patients with schizophrenia and co-occurring cannabis dependence. We utilized a 28-day cannabis abstinence paradigm to investigate the state-dependent effects of cannabis on select cognitive outcomes in cannabis dependent patients with schizophrenia and non-psychiatric controls...
April 26, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28434642/-late-life-depression-or-prodromal-alzheimer-s-disease-which-tools-for-the-differential-diagnosis
#2
A-I Gasser, V Salamin, S Zumbach
INTRODUCTION: Depression and Alzheimer's disease are both very frequent in elderly people. Cognitive deficits are the hallmark of Alzheimer's disease, but they are also common in depressed elderly people who often present cognitive deficits such as memory, attention and executive function problems. On the other hand, people with early Alzheimer's disease demonstrate emotional and behavioral disorders generally encountered in depression such as loss of energy, apathy, mood disorder, and irritability...
April 20, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28432781/cognitive-functioning-and-emotion-processing-in-breast-cancer-survivors-and-controls-an-erp-pilot-study
#3
Janine Wirkner, Mathias Weymar, Andreas Löw, Carmen Hamm, Anne-Marie Struck, Clemens Kirschbaum, Alfons O Hamm
Diagnosis and treatment of breast cancer is a very emotionally aversive and stressful life event, which can lead to impaired cognitive functioning and mental health. Breast cancer survivors responding with repressive emotion regulation strategies often show less adaptive coping and adverse outcomes. We investigated cognitive functioning and neural correlates of emotion processing using ERPs. Self-report measures of depression, anxiety, and fatigue, as well as hair cortisol as an index of chronic stress, were assessed...
April 22, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28432516/the-tower-of-london-tol-in-italy-standardization-of-the-tol-test-in-an-italian-population
#4
Maddalena Boccia, Dario Marin, Giovanni D'Antuono, Paola Ciurli, Chiara Incoccia, Gabriella Antonucci, Cecilia Guariglia, Laura Piccardi
Deficit in planning and problem-solving, affecting a wide range of neuropsychological patients, has been widely investigated using the Tower of London (ToL) test, as developed by Shallice (Philos Trans R Soc Lond Ser B Biol Sci 298:199-209, 1). The ToL taps on several executive functions (EF), such as planning, time for planning or rule breaks, which may be usefully indexed by different ToL measurements. However, in its original version, the different aspects involved in ToL are not evaluated in a specific way...
April 21, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28431031/sandbagging-on-the-immediate-post-concussion-assessment-and-cognitive-testing-impact-in-a-high-school-athlete-population
#5
Kathryn L Higgins, Robert L Denney, Arthur Maerlender
The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a computerized neuropsychological test battery commonly used to assess cognitive functioning after a concussion. It is recommended that application of ImPACT utilizes a baseline administration so athletes have an individualized baseline with which to compare post-injury results should they sustain a concussion. It has been suggested that athletes may provide suboptimal effort, called "sandbagging," in order to return to their baseline cognitive scores, and thus to play, more quickly...
May 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28427510/central-nervous-system-gliomas
#6
REVIEW
Michele Reni, Elena Mazza, Silvia Zanon, Gemma Gatta, Charles J Vecht
Evidence-based practical guidelines on diagnosis, prognosis, and treatment on the most frequent adult brain tumours are delineated. In Europe, 27,000 new cases of malignant glial tumours and 1000 new cases of malignant ependymal tumours are diagnosed every year. The most common glial tumours are glioblastoma multiforme and anaplastic glioma, comprising more than 50% and 10%, respectively, of the total gliomas. Prognosis of gliomas is generally poor. Environmental and genetic factors have been correlated with an increased risk of developing brain tumours...
May 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28426248/variability-in-neurocognitive-performance-age-gender-and-school-related-differences-in-children-and-from-ages-6-to-12
#7
Renata Kochhann, Hosana Alves Gonçalves, Janice da Rosa Pureza, Vanisa Fante Viapiana, Flavia Dos Passos Fonseca, Rochele Paz Fonseca, Jerusa Fumagali Salles
Cognitive development in children presents peculiarities according to groups of age, gender, and type of school. Few studies have been investigating the effects of all these factors. The aim of this study was to investigate the main effects and the interactions of age, gender, and type of school in 419 children from ages 6 to 12 years old evaluated by the Child Brief Neuropsychological Assessment Battery (NEUPSILIN-Inf). Older children, children in private schools and girls presented better results. Interactions between all three independent variables were observed in different cognitive domains...
April 20, 2017: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/28424901/driving-with-a-neurodegenerative-disorder-an-overview-of-the-current-literature
#8
REVIEW
Milou Jacobs, Ellen P Hart, Raymund A C Roos
Driving is important for employment, social activities, and for the feeling of independence. The decision to cease driving affects the quality of life and has been associated with reduced mobility, social isolation, and sadness. Patients with neurodegenerative disorders can experience difficulties while driving due to their cognitive, motor, and behavioral impairments. The aim of this review is to summarize the available literature on changes in driving competence and behavior in patients with neurodegenerative disorders, with a particular focus on Huntington's (HD), Parkinson's (PD), and Alzheimer's disease (AD)...
April 19, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28421910/multi-step-treatment-for-acquired-alexia-and-agraphia-part-ii-a-dual-route-error-scoring-system
#9
Katrina Ross, Jeffrey P Johnson, Swathi Kiran
Dual-route neuropsychological models posit two distinct but interrelated pathways for reading and writing: the lexical and the sublexical. Individuals with reading/writing deficits often rely on the combined power of the integrated system to perform print-processing tasks. The resultant errors reflect varying degrees of lexical and sublexical accuracy in a single production; however, no system presently exists to analyze errors robustly in both routes. The goal of this project was to develop a system that simultaneously, quantitatively, and qualitatively captures changes in lexical and sublexical errors following treatment...
April 19, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28421717/cognitive-profiles-in-euthymic-patients-with-bipolar-disorders-results-from-the-face-bd-cohort
#10
Paul Roux, Aurélie Raust, Anne Sophie Cannavo, Valérie Aubin, Bruno Aouizerate, Jean-Michel Azorin, Frank Bellivier, Raoul Belzeaux, Thierry Bougerol, Iréna Cussac, Philippe Courtet, Bruno Etain, Sébastien Gard, Sophie Job, Jean-Pierre Kahn, Marion Leboyer, Emilie Olié, Chantal Henry, Christine Passerieux
OBJECTIVES: Although cognitive deficits are a well-established feature of bipolar disorders (BD), even during periods of euthymia, little is known about cognitive phenotype heterogeneity among patients with BD. METHODS: We investigated neuropsychological performance in 258 euthymic patients with BD recruited via the French network of expert centers for BD. We used a test battery assessing six domains of cognition. Hierarchical cluster analysis of the cross-sectional data was used to determine the optimal number of subgroups and to assign each patient to a specific cognitive cluster...
April 19, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28421079/severe-sequelae-to-mold-related-illness-as-demonstrated-in-two-finnish-cohorts
#11
Tamara Tuuminen, Kyösti Sakari Rinne
The presence of toxic indoor molds with accompanying bacterial growth is clearly detrimental to human health. The pathophysiological and toxicological effects of toxins and structural components of molds and bacteria have been clarified in experiments conducted in tissue culture and animals, and there is convincing epidemiologic evidence; nonetheless their implications for human health are either ignored or denied, at least in Finland. In this communication, we describe two cohorts suffering severe sequelae to mold-related illness...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28420323/study-protocol-insight-46-a-neuroscience-sub-study-of-the-mrc-national-survey-of-health-and-development
#12
Christopher A Lane, Thomas D Parker, Dave M Cash, Kirsty Macpherson, Elizabeth Donnachie, Heidi Murray-Smith, Anna Barnes, Suzie Barker, Daniel G Beasley, Jose Bras, David Brown, Ninon Burgos, Michelle Byford, M Jorge Cardoso, Ana Carvalho, Jessica Collins, Enrico De Vita, John C Dickson, Norah Epie, Miklos Espak, Susie M D Henley, Chandrashekar Hoskote, Michael Hutel, Jana Klimova, Ian B Malone, Pawel Markiewicz, Andrew Melbourne, Marc Modat, Anette Schrag, Sachit Shah, Nikhil Sharma, Carole H Sudre, David L Thomas, Andrew Wong, Hui Zhang, John Hardy, Henrik Zetterberg, Sebastien Ourselin, Sebastian J Crutch, Diana Kuh, Marcus Richards, Nick C Fox, Jonathan M Schott
BACKGROUND: Increasing age is the biggest risk factor for dementia, of which Alzheimer's disease is the commonest cause. The pathological changes underpinning Alzheimer's disease are thought to develop at least a decade prior to the onset of symptoms. Molecular positron emission tomography and multi-modal magnetic resonance imaging allow key pathological processes underpinning cognitive impairment - including β-amyloid depostion, vascular disease, network breakdown and atrophy - to be assessed repeatedly and non-invasively...
April 18, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28413982/optimizing-adas-cog-worksheets-a-survey-of-clinical-trial-raters-perceptions
#13
Stephen M Meyer, Kristina A Bertzos, Magdalena Perez, Donald Connor, Kimberly Schafer, Sarah Walter
The Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) remains the most widely used test of longitudinal cognitive functioning in Alzheimer's disease (AD) clinical trials. Unlike most neuropsychological tests, the ADAS-Cog source documentation worksheets are not uniform across clinical trials, and vary by document layout, inclusion of administration and/or scoring instructions, and documentation of subtest scoring (e.g., recording correct versus incorrect scores), among other differences. Many ADAS-Cog test administrators (raters) participate in multiple AD trials and switching between different ADAS-Cog worksheets may increase the likelihood of administration and/or scoring mistakes that lessen the reliability of the instrument...
April 17, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28413625/hiv-associated-neurocognitive-disorders-recent-advances-in-pathogenesis-biomarkers-and-treatment
#14
REVIEW
Antonia Carroll, Bruce Brew
HIV-associated neurocognitive disorders (HAND) remain prevalent despite plasma viral suppression by antiretroviral agents. In fact, the prevalence of milder subtypes of cognitive impairment is increasing. Neuropsychologic testing remains the "gold standard" of diagnosis; however, this is time consuming and costly in a resource-poor environment. Recently developed screening tools, such as CogState and the revised HIV dementia scale, have very good sensitivity and specificity in the more severe stages of HAND...
2017: F1000Research
https://www.readbyqxmd.com/read/28412978/the-need-for-harmonisation-and-innovation-of-neuropsychological-assessment-in-neurodegenerative-dementias-in-europe-consensus-document-of-the-joint-program-for-neurodegenerative-diseases-working-group
#15
REVIEW
Alberto Costa, Thomas Bak, Paolo Caffarra, Carlo Caltagirone, Mathieu Ceccaldi, Fabienne Collette, Sebastian Crutch, Sergio Della Sala, Jean François Démonet, Bruno Dubois, Emrah Duzel, Peter Nestor, Sokratis G Papageorgiou, Eric Salmon, Sietske Sikkes, Pietro Tiraboschi, Wiesje M van der Flier, Pieter Jelle Visser, Stefano F Cappa
Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status.Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use...
April 17, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28411105/long-term-cognitive-functioning-and-psychological-well-being-in-surgically-treated-low-grade-glioma-patients
#16
Fabio Campanella, Alvisa Palese, Fabio Del Missier, Renzo Moreale, Tamara Ius, Tim Shallice, Franco Fabbro, Miran Skrap
OBJECTIVE: The aim of this work is to provide an in-depth investigation of the impact of Low Grade Gliomas (LGG) and their surgery on patients' cognitive and emotional functioning and well-being, carried out via a comprehensive and multiple-measure psychological and neuropsychological assessment. PATIENTS AND METHODS: Fifty surgically treated LGG patients were evaluated 40 months after surgery on their functioning over six different cognitive domains, three core affective/emotional aspects, and three different psychological well-being measures to obtain a clearer picture of the long-term impact of illness and surgery on their psychological and relational world...
April 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28410657/assessment-of-the-hispanic-cognitively-impaired-elderly-patient
#17
REVIEW
Liliana Ramirez Gomez, Felipe A Jain, Lina M D'Orazio
Hispanics are the largest minority group in the United States, approximately 7% of the population older than 65. They often encounter challenges related to health care access and quality of care. The prevalence of dementia among Hispanics is higher than that of non-Hispanic whites and they frequently present at a more advanced stage of illness. Cognitive evaluation should take into account sociodemographic information and cultural factors to avoid misdiagnosis and guide management. A provider who has knowledge of Hispanic culture should conduct the neuropsychological assessment, and tests used to measure cognitive functioning should be developed for Hispanics in the United States...
May 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28410656/the-role-of-neuropsychology-in-the-assessment-of-the-cognitively-impaired-elderly
#18
REVIEW
Po H Lu, Grace J Lee
Cognitive abilities decline with age and older adults, as a group, are at increased risk for developing age-related cognitive disorders. Neuropsychological evaluation provides objective quantification of the type and severity of cognitive deficits that can affect the elderly population and elucidates a pattern of scores that provides diagnostic clues regarding etiology. It can also detect mild cognitive impairment that may not be evident on bedside assessment or mental status examination and provides critical information regarding the progression of cognitive changes through serial evaluations...
May 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28407518/evaluating-executive-function-in-patients-with-temporal-lobe-epilepsy-using-the-frontal-assessment-battery
#19
Elmira Agah, Nasima Asgari-Rad, Mona Ahmadi, Abbas Tafakhori, Vajiheh Aghamollaii
Previous studies have demonstrated executive dysfunction in patients with temporal lobe epilepsy (TLE). Frontal assessment battery (FAB) is a short neuropsychological tool that was developed for assessment of frontal lobe function in a clinical setting. The aim of the present study is to evaluate the clinical utility of FAB for detection of executive dysfunction in TLE patients. Forty-eight TLE patients and 48 sex and age-matched healthy controls participated in this study. Compared to healthy participants, the total FAB score was significantly lower among the TLE patients...
April 5, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28407029/shiraz-verbal-learning-test-svlt-normative-data-for-neurologically-intact-speakers-of-persian
#20
Fahimeh Rahmani, Hassan Haghshenas, Abdolrasoul Mehrabanpour, Arash Mani, Mohammad Mahmoodi
Objective: Memory assessment plays an important role in the diagnosis of neurodegenerative disorders. Several tests, such as the California Verbal Learning Test (CVLT), have been developed for this purpose, yet a variety of different factors can affect one's performance on such tests, the most important of which are demographic and cultural variables. The present study examined the norming process performed on the CVLT-revised and aimed to devise a new test, the Shiraz Verbal Learning Test (SVLT), to better meet the needs of speakers of Persian...
April 12, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
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