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https://www.readbyqxmd.com/read/28330095/potential-mosquito-repellent-compounds-of-ocimum-species-against-3n7h-and-3q8i-of-anopheles-gambiae
#1
Venugopal Gaddaguti, Talluri Venkateswara Rao, Allu Prasada Rao
Mosquitoes are exceptionally efficient in detecting their hosts for blood meal using odorant binding proteins, viz. 3N7H and 3Q8I and spread several dreadful diseases. DEET is a synthetic mosquito repellent widely used all over world for protection against mosquito bite. Reports reveal that, synthetic mosquito repellents may pose health problems in considerably large population. In view of the above fact, we made an attempt to discover efficient and novel natural mosquito repellent compounds with least impact on human health...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28329329/increased-transmissibility-of-leishmania-donovani-from-the-mammalian-host-to-vector-sand-flies-after-multiple-exposures-to-sand-fly-bites
#2
Joanna G Valverde, Andrea Paun, Ehud Inbar, Audrey Romano, Michael Lewis, Kashinath Ghosh, David Sacks
Background: Patients with active visceral leishmaniasis are important reservoirs in the anthroponotic transmission cycle of Leishmania donovani. The role of the blood or skin as a source of infection to sand flies remains unclear, and the possible effect of multiple exposures to fly bites on transmissibility has not been addressed. Methods: L. donovani infected hamsters were exposed to xenodiagnoses with Lutzomyia longipalpis on the same or different sites on the abdomen on two consecutive days, or by artificial feeding on the skin or blood...
March 9, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28329001/experimental-demonstration-of-the-possible-role-of-acanthamoeba-polyphaga-in-the-infection-and-disease-progression-in-buruli-ulcer-bu-using-icr-mice
#3
Bright K Azumah, Phyllis G Addo, Alfred Dodoo, Gordon Awandare, Lydia Mosi, Daniel A Boakye, Michael D Wilson
The transmission of Buruli ulcer (BU), caused by Mycobacterium ulcerans (MU), remains puzzling although a number of hypothesis including through bites of infected aquatic insects have been proposed. We report the results of experiments using ICR mice that give credence to our hypothesis that Acanthamoeba species may play a role in BU transmission. We cocultured MU N2 and MU 1615 which expresses red fluorescent protein (RFP) and Acanthamoeba polyphaga (AP), and confirmed infected AP by Ziehl-Neelsen (ZN) staining...
2017: PloS One
https://www.readbyqxmd.com/read/28327073/the-influence-of-axial-grooves-on-dislodgment-resistance-of-prosthetic-metal-crowns-in-canine-teeth-of-dogs
#4
Stephanie Goldschmidt, Caitlyn J Collins, Scott Hetzel, Heidi-Lynn Ploeg, Jason W Soukup
The reported failure rate for full veneer crowns of canine teeth of dogs is suboptimal, particularly in teeth with naturally poor retentive features, such as those with low height/diameter (H/D) ratios or high convergence angles (CAs). The objective of the present study was to evaluate the application of axial grooves in an effort to develop a crown preparation design that enhances the retention of full veneer crowns in dogs. Crown dislodgment testing was performed on cast alloy dies of canine teeth with unfavorable retention features (low H/D and high CA) prepared with (n = 14) and without axial grooves (n = 15) to evaluate the force required to dislodge a cemented full veneer crown...
September 2016: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28326710/-finite-elemental-analysis-of-the-influence-of-mandibular-plane-angle-on-the-stress-distribution-of-implant-tooth
#5
Xing Weibin, Zheng Shuxian, Yang Shiyi
OBJECTIVE: Finite elemental analysis of the mechanical characteristics of a first mandibular implant molar under different mandibular plane angles determines the load conditions on the implant, thereby providing guidance for clinical application. METHODS: CT data of three mandibular plane angles (low, average, high) were collected. A finite elemental combination model of a dental implant was constructed. The orthogonal experimental research was designed. Results followed data collection and analysis...
October 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28325914/exploring-the-diversity-of-blood-sucking-diptera-in-caves-of-central-africa
#6
Judicaël Obame-Nkoghe, Nil Rahola, Diego Ayala, Patrick Yangari, Davy Jiolle, Xavier Allene, Mathieu Bourgarel, Gael Darren Maganga, Nicolas Berthet, Eric-Maurice Leroy, Christophe Paupy
Caves house pathogenic microorganisms, some of which are transmitted by blood-sucking arthropods. In Africa, previous studies identified mosquitoes, sand flies and biting midges as the main potential vectors of cave-dwelling pathogens. However, to understand their involvement in pathogen spillover, it is crucial to characterize their diversity, community composition and dynamics. Using CDC light traps, we collected hematophagous Diptera in six caves of Gabon during one-shot or longitudinal sampling, and investigated their species diversity and dynamics in relation with external rainfall...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28325640/computed-tomography-based-3-dimensional-finite-element-analyses-of-various-types-of-plates-placed-for-a-virtually-reduced-unilateral-condylar-fracture-of-the-mandible-of-a-patient
#7
Kazuhiro Murakami, Kazuhiko Yamamoto, Tsutomu Sugiura, Satoshi Horita, Yumiko Matsusue, Tadaaki Kirita
PURPOSE: This study was performed to evaluate stresses in various types of plates placed for a virtually reduced unilateral condylar fracture of the mandible using computed tomography-based 3-dimensional finite element (FE) models of a patient to select the optimal plate system. MATERIALS AND METHODS: A computed tomography-based FE model of the mandible of a patient with a unilateral condylar fracture was constructed. The fracture was virtually reduced and fixed with 1 straight titanium plate; 2 straight titanium plates; 2 straight poly-L-lactic acid plates; and 4-hole (box), 5-hole (strut), and 7-hole (lambda) condylar plates...
February 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28324164/novel-intraoperative-use-of-the-tensipresser-to-assess-factors-predictive-of-pancreatic-fistula-after-pancreaticoduodenectomy
#8
Manabu Mikamori, Kunihito Gotoh, Hidenori Takahashi, Hirofumi Akita, Akira Tomokuni, Shogo Kobayashi, Masayuki Ohue, Yoshiyuki Fujiwara, Masahiko Yano, Osamu Ishikawa, Masato Sakon
PURPOSES: Pancreatic fistula (PF) is a challenging complication of pancreaticoduodenectomy (PD). 'Soft pancreas' is reported as a risk factor for PF; however, palpation by the surgeon is not an objective method of evaluating pancreatic texture. We conducted this study to investigate whether a texture analyzer called a "Tensipresser" can be used to quantify pancreatic tissue hardness and predict the development of postoperative PF. METHODS: We assessed pancreatic texture in 85 patients who underwent PD...
March 21, 2017: Surgery Today
https://www.readbyqxmd.com/read/28323644/pediatric-acute-compartment-syndrome
#9
Kristin S Livingston, Michael P Glotzbecker, Benjamin J Shore
Pediatric acute compartment syndrome (PACS) is a clinical entity that must be carefully differentiated from the adult version (ie, acute compartment syndrome). Healthcare providers must understand the variable etiologies of PACS, of which trauma is the most common but can also include vascular insult, infection, surgical positioning, neonatal phenomena, overexertion, and snake and insect bites. In addition to the unique etiologies of PACS, providers must also recognize the different signs and symptoms of PACS...
March 17, 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28323526/addiction-to-snake-venom
#10
Saibal Das, Preeti Barnwal, Tanay Maiti, Anand Ramasamy, Somnath Mondal, Dinesh Babu
The nature of addiction depends on various factors. The tendency to have already used several addictive substances and to seek high sensation experiences as a result of specific personality traits may lead to extreme and peculiar forms of addictions. Even belonging to specific social and cultural background may lead to such forms of addiction such as intentional snake bite and willful envenomation. In this article, we have discussed the peculiarities and practical insight of such addiction to snake venom. The possible molecular mechanism behind such venom-mediated reinforcement has also been highlighted...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28323468/potential-high-risk-areas-for-zika-virus-transmission-in-the-contiguous-united-states
#11
Enbal Shacham, Erik J Nelson, Daniel F Hoft, Mario Schootman, Alexander Garza
OBJECTIVES: To understand where transmission of Zika virus has the highest likelihood to occur in the contiguous United States with regard to its transmission both sexually and via Aedes aegypti mosquito bites. METHODS: We evaluated the 2 routes of transmission risk with predictors of sexually transmitted infections (percentage women of childbearing age, birthrate, gonorrhea and chlamydia rates, concentrated disadvantage) as a surrogate for unprotected sexual activity and the demographic distribution of the A...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28322713/acute-tetraplegia-caused-by-rat-bite-fever-in-snake-keeper-and-transmission-of-streptobacillus-moniliformis
#12
Tobias Eisenberg, Simon Poignant, Youenn Jouan, Ahmad Fawzy, Werner Nicklas, Christa Ewers, Laurent Mereghetti, Antoine Guillon
We report acute tetraplegia caused by rat bite fever in a 59-year old man (snake keeper) and transmission of Streptobacillus moniliformis. We found an identical characteristic bacterial pattern in rat and human samples, which validated genotyping-based evidence for infection with the same strain, and identified diagnostic difficulties concerning infection with this microorganism.
April 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28321813/harnessing-the-immune-system-against-leukemia-monoclonal-antibodies-and-checkpoint-strategies-for-aml
#13
Lucia Masarova, Hagop Kantarjian, Guillermo Garcia-Mannero, Farhad Ravandi, Padmanee Sharma, Naval Daver
Acute myeloid leukemia (AML) is the most common leukemia among adults and is associated with a poor prognosis, especially in patients with adverse prognostic factors, older age, or relapsed disease. The last decade has seen a surge in successful immune-based therapies in various solid tumors; however, the role of immune therapies in AML remains poorly defined. This chapter describes the rationale, clinical data, and toxicity profiles of immune-based therapeutic modalities in AML including naked and conjugated monoclonal antibodies, bispecific T-cell engager antibodies, chimeric antigen receptor (CAR)-T cells, and checkpoint blockade via blockade of PD1/PDL1 or CTLA4...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28321400/toward-elimination-of-dog-mediated-human-rabies-experiences-from-implementing-a-large-scale-demonstration-project-in-southern-tanzania
#14
Emmanuel Abraham Mpolya, Tiziana Lembo, Kennedy Lushasi, Rebecca Mancy, Eberhard M Mbunda, Selemani Makungu, Matthew Maziku, Lwitiko Sikana, Gurdeep Jaswant, Sunny Townsend, François-Xavier Meslin, Bernadette Abela-Ridder, Chanasa Ngeleja, Joel Changalucha, Zacharia Mtema, Maganga Sambo, Geofrey Mchau, Kristyna Rysava, Alphoncina Nanai, Rudovick Kazwala, Sarah Cleaveland, Katie Hampson
A Rabies Elimination Demonstration Project was implemented in Tanzania from 2010 through to 2015, bringing together government ministries from the health and veterinary sectors, the World Health Organization, and national and international research institutions. Detailed data on mass dog vaccination campaigns, bite exposures, use of post-exposure prophylaxis (PEP), and human rabies deaths were collected throughout the project duration and project areas. Despite no previous experience in dog vaccination within the project areas, district veterinary officers were able to implement district-wide vaccination campaigns that, for most part, progressively increased the numbers of dogs vaccinated with each phase of the project...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28321362/from-eggs-to-bites-do-ovitrap-data-provide-reliable-estimates-of-aedes-albopictus-biting-females
#15
Mattia Manica, Roberto Rosà, Alessandra Della Torre, Beniamino Caputo
BACKGROUND: Aedes albopictus is an aggressive invasive mosquito species that represents a serious health concern not only in tropical areas, but also in temperate regions due to its role as vector of arboviruses. Estimates of mosquito biting rates are essential to account for vector-human contact in models aimed to predict the risk of arbovirus autochthonous transmission and outbreaks, as well as nuisance thresholds useful for correct planning of mosquito control interventions. Methods targeting daytime and outdoor biting Ae...
2017: PeerJ
https://www.readbyqxmd.com/read/28321256/biochemical-and-clinical-assessments-of-segmental-maxillary-posterior-tooth-intrusion
#16
Jintana Tasanapanont, Tanapan Wattanachai, Janya Apisariyakul, Peraphan Pothacharoen, Siriwan Ongchai, Prachya Kongtawelert, Marit Midtbø, Dhirawat Jotikasthira
Objective. To compare chondroitin sulphate (CS) levels around maxillary second premolars, first molars, and second molars between the unloaded and the loaded periods and to measure the rates of intrusion of maxillary posterior teeth during segmental posterior tooth intrusion. Materials and Methods. In this prospective clinical study, 105 teeth (from 15 patients exhibiting anterior open bite and requiring maxillary posterior tooth intrusion) were studied. Competitive ELISA was used to detect CS levels. Dental casts (during the unloaded and loaded periods) were scanned, and posterior tooth intrusion distances were measured...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28320537/a-randomized-clinical-trial-comparing-2-ibuprofen-formulations-in-patients-with-acute-odontogenic-pain
#17
Tanjit Taggar, Di Wu, Asma A Khan
INTRODUCTION: Ibuprofen sodium dihydrate, a new formulation of ibuprofen, was introduced with the claim of faster onset of analgesia. Most of the data on this new ibuprofen formulation are drawn from studies using the oral surgery model. Because this model differs significantly from the endodontic pain model, we conducted a study comparing ibuprofen sodium dihydrate with conventional ibuprofen acid in endodontic pain patients. METHODS: This randomized, double-masked study recruited subjects experiencing moderate to severe pain from a tooth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis (n = 41)...
March 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28319627/what-s-eating-you-lone-star-tick-amblyomma-americanum
#18
H Harris Reynolds, Dirk M Elston
Amblyomma americanum, also known as the lone star tick, is found in much of the eastern United States. Since the mid-20th century, the lone star tick has been implicated in human disease. Today, A americanum remains an important vector for tick-borne illness. In addition to others, species of Rickettsia, Ehrlichia, and Borrelia are all transmitted by the lone star tick. Recently described conditions such as Southern tick-associated rash illness and anaphylaxis to red meat following tick bites have been attributed to the lone star tick...
February 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28318918/comparison-of-functional-outcomes-and-patient-reported-satisfaction-between-titanium-and-absorbable-plates-and-screws-for-fixation-of-mandibular-fractures-a-one-year-prospective-study
#19
Maria Belén Leno, Stanley Yung Liu, Chien-Tzung Chen, Han-Tsung Liao
PURPOSE: The aim of this study is to compare the 1-year functional outcomes and patient-reported satisfaction in treating mandibular fractures between resorbable and titanium fixation devices. MATERIALS AND METHODS: A 1-year prospective study was conducted; 41 consecutive patients presenting with mandibular fractures were included. A resorbable system was used in 21 patients, while in 20 patients a titanium fixation device was used. Functional outcome was evaluated objectively at several time points (2, 4 and 6 weeks, 3 and 6 months, and 1 year after surgery)...
February 13, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28318870/anterior-open-bite-correction-by-le-fort-i-osteotomy-with-or-without-anterior-segmentation-which-is-more-stable
#20
I N Ismail, Y Y Leung
A retrospective cohort study was conducted to analyze the relapse rate of anterior open bite (AOB) correction comparing Le Fort I osteotomy with and without anterior segmentation. The risk factors that might contribute to relapse were also assessed. Lateral cephalograms obtained at six different times were analyzed. A total of 81 patients with AOB were recruited. Thirty-five patients underwent Le Fort I osteotomy without anterior segmentation and 46 patients underwent anterior segmentation. Le Fort I osteotomy with anterior segmentation resulted in significantly more AOB relapse when compared to that without anterior segmentation at 7 weeks postoperative (15...
March 15, 2017: International Journal of Oral and Maxillofacial Surgery
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