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primary peritoneal carcinoma

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https://www.readbyqxmd.com/read/28206948/primary-pelvic-papillary-thyroid-carcinoma-with-metastases-to-peritoneal-surfaces
#1
Melissa Miles, Chelsea Ward, Christopher M Pezzi, Cynthia A Kelley, Todd Pezzi, Jere Seelaus, Mark Shahin, Glenn McGrath
No abstract text is available yet for this article.
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28187099/serous-tubal-intraepithelial-carcinoma-associated-with-extraovarian-metastases
#2
Stephanie Schneider, Sebastian Heikaus, Philipp Harter, Florian Heitz, Christoph Grimm, Beyhan Ataseven, Sonia Prader, Christian Kurzeder, Thomas Ebel, Alexander Traut, Andreas du Bois
OBJECTIVE: The evolving knowledge of ovarian carcinogenesis sets the stage for our understanding of high-grade serous pelvic carcinoma (HGSC). Findings in prophylactic surgery introduced serous tubal intraepithelial carcinoma (STIC) as potential precursor of HGSC. The present study explores whether STIC instead should already be considered as an early stage of HGSC with a need for comprehensive staging and therapy. PATIENTS AND METHODS: We identified all consecutive patients with HGSC who received first-line therapy in our referral center for gynecologic oncology from January 2011 to April 2016...
March 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28163816/plasmacytoid-urothelial-carcinoma-puc-imaging-features-with-histopathological-correlation
#3
Andrew D Chung, Nicola Schieda, Trevor A Flood, Ilias Cagiannos, Kien T Mai, Shawn Malone, Christopher Morash, Shaheed W Hakim, Rodney H Breau
INTRODUCTION: Plasmacytoid urothelial carcinoma (PUC) is a high-grade variant of conventional urothelial cell carcinoma. This study is the first to describe the imaging findings of PUC, which are previously unreported, using clinical and histopathological correlation. METHODS: With internal review board approval, we identified 22 consecutive patients with PUC from 2007-2014. Clinical parameters, including age, gender, therapy, surgical margins, and long-term outcome, were recorded...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28133310/-a-case-of-mucinous-adenocarcinoma-of-the-appendix-with-peritoneal-dissemination-diagnosed-by-laparoscopic-abdominal-exploration-and-appendectomy
#4
Toru Tonooka, Nobuhiro Takiguchi, Hiroshi Yamamoto, Yoshihiro Nabeya, Atsushi Ikeda, Osamu Kainuma, Hiroaki Soda, Shunsuke Imanishi, Hidehito Arimitsu, Ryosuke Kobayashi, Tomofumi Chibana, Fumitaka Ishige, Matsuo Nagata
We report a case of mucinous adenocarcinoma of the appendix with peritoneal dissemination diagnosed by laparoscopic abdominal exploration and appendectomy. A man in his 60's was diagnosed with peritoneal dissemination of mucinous adenocarcinoma incidentally during an operation for an inguinal hernia. Carcinoma of the appendix was suspected as the primary lesion after further examination. We performed laparoscopic abdominal exploration and appendectomy. The purpose of the operation was to detect the primary lesion, make a pathological diagnosis, and to evaluate the extent of peritoneal dissemination...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133240/-a-case-of-primary-peritoneal-cancer-successfully-treated-with-debulking-surgery-and-postoperative-chemotherapy
#5
Koki Maeda, Masami Tabata, Taiki Moriyama, Tatsuya Sakamoto, Yu Fujimura, Ichiro Ohsawa, Kenji Kato, Makoto Iwata, Takayuki Sanda
A 52-year-old woman with abdominal pain and a feeling of incomplete evacuation visited a local clinic. Enlargement of the right ovary was detected, and the patient was referred to the gynecological department of our hospital. CT and MRI revealed a round-shaped mass, 8 cm in diameter, with cystic and solid components in the Douglas pouch. The patient underwent a laparotomy under the diagnosis of ovarian cancer. Intraoperatively, both the ovaries appeared normal and the tumor strongly adhered to the rectum and uterus...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133231/-a-long-surviving-case-of-unresectable-gall-bladder-carcinoma-treated-with-gemcitabine-based-chemotherapy
#6
Hiroyoshi Matsukawa, Shigehiro Shiozaki, Daisuke Satoh, Hiroyuki Araki, Naoki Mimura, Toshihiro Ogawa, Hitoshi Idani, Yasutomo Ojima, Masao Harano, Takashi Kanazawa, Yasuhiro Choda, Daisuke Sumitani, Michihiro Ishida, Masazumi Okajima, Motoki Ninomiya
We report a 5-year surviving patient with unresectable gall bladder carcinoma treated with gemcitabine(GEM)-based chemotherapy. A 64-year-old man was diagnosed with unresectable gall bladder carcinoma with peritoneal dissemination based on laparotomy findings. Two months later, he started to receive GEM chemotherapy. Twelve months after surgery, the patient chose to suspend GEM treatment. One year and 10 months later, multiple lung metastases appeared and GEM was restarted in combination with UFT. Although the primary lesion and lung metastases gradually progressed, the patient maintained a good quality of life...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133123/-a-case-of-laparoscopic-resection-of-peritoneal-hepatocellular-carcinoma-recurrence-after-percutaneous-ethanol-injection-therapy
#7
Daisuke Muroya, Masafumi Yasunaga, Yusaku Date, Shogo Fukutomi, Nobuhisa Shirahama, Shoichiro Arai, Yohei Nakama, Ryuichi Kawahara, Hisamune Sakai, Hiroto Ishikawa, Toru Hisaka, Jun Akiba, Yoshito Akagi, Hiroyuki Tanaka, Koji Okuda
Needle tract implantation after percutaneous ethanol injection therapy(PEIT)for hepatocellular carcinoma(HCC)is rare. Surgical treatment of such HCC implants is still controversial. We herein report the case of a patient who underwent laparoscopic resection for peritoneal dissemination after PEIT. An 81-year-old man underwent PEIT for primary HCC at another hospital. Thereafter, percutaneous radiofrequency ablation(RFA)was performed twice for intrahepatic recurrence. After the second RFA, a mass lesion was detected at the subhepatic space on computed tomography(CT)...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28123552/the-diagnostic-utility-of-pax8-immunostaining-of-malignant-peritoneal-mesothelioma-presenting-as-serous-ovarian-carcinoma-a-single-center-report-of-two-cases
#8
Kohei Nakamura, Kentaro Nakayama, Risa Nagaoka, Kiyoka Nishisako, Masako Ishikawa, Hiroshi Katagiri, Tomoka Ishibashi, Emi Sato, Chika Amano, Satoru Kyo
Malignant peritoneal mesotheliomas (MPMs) are rare and progressive tumors, which may present similarly to primary peritoneal carcinoma or ovarian carcinoma (OC). The current study reports two cases of MPM that initially presented with the features of OC, for which paired box 8 (PAX8) immunostaining was found to be useful for diagnosis. The two patients were women, aged 58 and 56 years, respectively. The primary presenting symptoms and clinical findings included prolonged abdominal pain, abdominal swelling and cough...
January 2017: Oncology Letters
https://www.readbyqxmd.com/read/28108967/specific-sites-of-metastases-in-invasive-lobular-carcinoma-a-retrospective-cohort-study-of-metastatic-breast-cancer
#9
Masayuki Inoue, Hiroshi Nakagomi, Haruka Nakada, Kazushige Furuya, Kou Ikegame, Hideki Watanabe, Masao Omata, Toshio Oyama
BACKGROUND: Invasive lobular carcinoma (ILC) is known to be the second most common histological type following invasive ductal carcinoma (IDC). Definitive clinical features of ILC are controversial. METHODS: We retrospectively analyzed a cohort of 330 patients with metastatic breast cancer, 303 of IDC, 19 of ILC, and 8 of others. We compared the patient age and tumor-node-metastasis factors, disease-free survival (DFS), estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor 2 (HER2) expression at the primary site between ILC and IDC...
January 20, 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/28099801/highly-specific-and-sensitive-fluorescent-nanoprobes-for-image-guided-resection-of-sub-millimeter-peritoneal-tumors
#10
Aaron H Colby, Samantha M Berry, Ann M Moran, Kristine Amber Pasion, Rong Liu, Yolonda L Colson, Nelson Ruiz-Opazo, Mark W Grinstaff, Victoria L M Herrera
A current challenge in the treatment of peritoneal carcinomatosis is the inability to detect, visualize, and resect small or microscopic tumors of pancreatic, ovarian, or mesothelial origin. In these diseases, the completeness of primary tumor resection is directly correlated with patient survival, and hence, identifying small sub-millimeter tumors (i.e., disseminated disease) is critical. Thus, new imaging techniques and probes are needed to improve cytoreductive surgery and patient outcomes. Highly fluorescent rhodamine-labeled expansile nanoparticles (HFR-eNPs) are described for use as a visual aid during cytoreductive surgery of pancreatic carcinomatosis...
February 1, 2017: ACS Nano
https://www.readbyqxmd.com/read/28099523/the-role-of-liquid-based-cytology-and-ancillary-techniques-in-the-peritoneal-washing-analysis-our-institutional-experience
#11
Esther Rossi, Tommaso Bizzarro, Maurizio Martini, Adhemar Longatto-Filho, Fernando Schmitt, Anna Fagotti, Giovanni Scambia, Gian Franco Zannoni
BACKGROUND: The cytological analysis of peritoneal effusions serves as a diagnostic and prognostic aid for either primary or metastatic diseases. Among the different cytological preparations, liquid based cytology (LBC) represents a feasible and reliable method ensuring also the application of ancillary techniques (i.e immunocytochemistry-ICC and molecular testing). METHODS: We recorded 10348 LBC peritoneal effusions between January 2000 and December 2014. They were classified as non-diagnostic (ND), negative for malignancy-NM, atypical-suspicious for malignancy-SM and positive for malignancy-PM...
2017: PloS One
https://www.readbyqxmd.com/read/28098079/hyperthermic-intraperitoneal-chemotherapy-for-peritoneal-surface-malignancies-a-single-institution-indian-experience
#12
S P Somashekhar, G Prasanna, Rajshekhar Jaka, Amit Rauthan, H S Murthy, Sunil Karanth
BACKGROUND: Cytoreductive surgery followed by hyper- thermic intraperitoneal chemotherapy (HIPEC) has shown better oncological outcomes in peritoneal surface malignancies (PSM). We assessed the feasibility and perioperative outcomes of this procedure in Indian patients. METHODS: In this prospective observational study from February 2013 to April 2015, we included 56 patients (41 females, 73.2%) with PSM. They had a good performance status, were either treatment-naïve or previously treated by surgery and systemic chemotherapy...
September 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/28076472/evaluation-of-lymphatic-spread-visceral-metastasis-and-tumoral-local-invasion-in-esophageal-carcinomas
#13
Francisco Tustumi, Cintia Mayumi Sakurai Kimura, Flavio Roberto Takeda, Rubens Antônio Aissar Sallum, Ulysses Ribeiro-Junior, Ivan Cecconello
Background: Knowing esophageal tumors behavior in relationship to lymph node involvement, distant metastases and local tumor invasion is of paramount importance for the best esophageal tumors management. Aim: To describe lymph node involvement, distant metastases, and local tumor invasion in esophageal carcinoma, according to tumor topography and histology. Methods: A total of 444 patients with esophageal squamous cell carcinoma and 105 adenocarcinoma were retrospectively analyzed...
November 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28060250/murine-experimental-model-of-original-tumor-development-and-peritoneal-metastasis-via-orthotopic-inoculation-with-ovarian-carcinoma-cells
#14
Yoshihiro Koya, Hiroaki Kajiyama, Wenting Liu, Kiyosumi Shibata, Takeshi Senga, Fumitaka Kikkawa
Epithelial ovarian carcinoma (EOC) is associated with a poor prognosis because it shows peritoneal dissemination. To improve the prognosis, it is important to control peritoneal dissemination. However, it is still unclear how tumor cells detach from primary lesions and attach to the mesothelium. The establishment of an appropriate animal model is needed to gain an understanding of the mechanism of peritoneal dissemination in vivo. In the current study, we introduce the process from the local injection of EOC cells into the murine ovarian surface to the development of metastasis, including the peritoneum and distant organs...
December 9, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28035252/signet-ring-colorectal-carcinoma-do-we-need-to-improve-the-treatment-algorithm
#15
Anup Sunil Tamhankar, Parag Ingle, Reena Engineer, Munita Bal, Vikas Ostwal, Avanish Saklani
AIM: To elaborate about this peculiar variant from a tertiary cancer center from India. METHODS: It's a retrospective study (2011-2014) of all patients diagnosed with signet ring colo-rectal cancer (SRCC). Various clinico-pathological variables were studied. RESULTS: One hundred and seventy consecutive patients with SRCC were diagnosed (11.4% of all colorectal cancers). Median Age of the cohort was 41 years. Most common location was recto-sigmoid area (54...
December 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28028263/-residual-disease-status-after-primary-cytoreductive-surgery-in-patients-with-advanced-ovarian-fallopian-tube-or-peritoneal-carcinoma-and-long-term-progression-free-survival
#16
Isao Otsuka, Takuto Matsuura
OBJECTIVE: To investigate residual disease status after primary cytoreductive surgery(PCS)in patients with advanced ovarian, Fallopian tube, or peritoneal carcinoma and long-term progression-free survival(PFS). METHODS: The study included patients with stage III C/IVepithelial ovarian, fallopian tube, or peritoneal carcinoma who had undergone surgery and carbo- platin/taxane chemotherapy, and had a PFSduration of ≥48 months. RESULTS: The study group consisted of 11 patients with stage III C disease, which accounted for 23%(8/35)of stage III C patients aged ≤59 years and 11%(3/27)of stage III C patients aged ≥60 years...
December 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28008196/clinical-characteristics-of-primary-peritoneal-carcinoma-patients-a-single-institution-experience-involving-8-patients
#17
Satomi Hattori, Hiroaki Kajiyama, Utako Fuji, Yuko Furui, Yuki Ishibashi, Yuka Hattori, Noriko Takahashi, Fumitaka Kikkawa, Toshiya Misawa
Primary peritoneal carcinoma (PPC) is treated similarly to advanced epithelial ovarian carcinoma (aEOC); however, the standard approach for the management of PPC is controversial. The objective of this study was to evaluate the clinical features and prognosis of those patients. A retrospective analysis was performed of eight patients with PPC between January 2008 and December 2015. Clinicopathologic parameters, the diagnostic modality, treatment, and oncologic outcome were analyzed. The median age at the time of diagnosis was 72...
December 2016: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/27994671/reduction-of-ca125-levels-during-neoadjuvant-chemotherapy-can-predict-cytoreduction-to-no-visible-residual-disease-in-patients-with-advanced-epithelial-ovarian-cancer-primary-carcinoma-of-fallopian-tube-and-peritoneal-carcinoma
#18
Jing Zeng, Jie Yin, Xiao Song, Ying Jin, Yan Li, Lingya Pan
Background and aims. To determine whether reduction of CA125 levels is a predictive factor for cytoreduction to no visible residual disease (NVRD) and chemotherapeutic sensitivity in advanced epithelial ovarian carcinoma (EOC), primary carcinoma of fallopian tube and peritoneal carcinoma patients who received neoadjuvant chemotherapy followed by interval debulking surgery (NAC-IDS). Methods. This was a single-team-based study of advanced EOC, primary carcinoma of fallopian tube and peritoneal carcinoma patients diagnosed between 1996 and 2015 at Peking Union Medical College Hospital...
2016: Journal of Cancer
https://www.readbyqxmd.com/read/27976970/comparison-of-survival-outcome-of-patients-with-primary-peritoneal-and-fallopian-tube-carcinoma-treated-with-neoadjuvant-chemotherapy-versus-primary-debulking-surgery
#19
Hooman Soleymani Majd, Lamiese Ismail, Kieran Hardern, Federico Ferrari, Sean Kehoe
This study examines the overall survival of primary peritoneal cancer (PPC), in those patients who had primary debulking surgery (PDS) followed by six cycles of chemotherapy versus those who had neoadjuvant chemotherapy (NACT). This was a prospective observational study performed at Oxford Gynaecological Cancer Centre, over a 5-year period. Eighty-seven patients were clinically suspected of having PPC. Histology confirmed that 64 of these were PPC, with the balance being tubal in origin. PDS was performed in 31 cases...
December 15, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27941567/a-serous-peritoneal-cancer-revealing-itself-with-double-breast-cancer-metastases-in-2-different-periods
#20
Kemal Beksac, Cigdem Irkkan, Guldeniz Argun, Bahadir Cetin
A 72-year-old woman presented with a mass on the right axilla. This was thought to be an occult breast cancer case, and the patient was treated with modified radical mastectomy, followed by hormonotherapy. Two years later she presented with incarcerated umbilical hernia. Pathology revealed Sister Mary Joseph's nodule inside the hernia sac. Further evaluation revealed that the primary tumor was papillary serous carcinoma of the peritoneal surface. The patient received adjuvant chemotherapy. Two years later the metastatic tumor was located on the other breast...
December 9, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
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