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Vidya Narayanaswami, Linda P Dwoskin
Obesity is a global epidemic that contributes to a number of health complications including cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders. Pharmacotherapeutic strategies to treat obesity are urgently needed. Research over the past two decades has increased substantially our knowledge of central and peripheral mechanisms underlying homeostatic energy balance. Homeostatic mechanisms involve multiple components including neuronal circuits, some originating in hypothalamus and brain stem, as well as peripherally-derived satiety, hunger and adiposity signals that modulate neural activity and regulate eating behavior...
October 20, 2016: Pharmacology & Therapeutics
No abstract text is available yet for this article.
April 21, 1951: Wiener Medizinische Wochenschrift
No abstract text is available yet for this article.
1954: Wiener Zeitschrift Für Nervenheilkunde und Deren Grenzgebiete
O Aigner
In 16 obese patients, the effect of beta-amino-isobutyl-benzol as polysterol-sulfonate on free fatty acids, triglycerides and i.v. GTT was compaired with that of a placebo. The question was to be answered if beta-amino-isobutyl-benzol worsens the GTT and if the lipolytic effect outranges lipolysis during fasting. No statistically significant change of the GTT, free fatty acids and triglycerides could be found between the beta-amino-isobutyl-benzol period and the placebo period.
January 1975: International Journal of Clinical Pharmacology and Biopharmacy
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