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Optic disc detection

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https://www.readbyqxmd.com/read/29339963/infiltrative-optic-neuropathies-opening-doors-to-sinister-pathologies
#1
Aastha Takkar, Darakshan Naheed, Mohit Dogra, Manoj K Goyal, Ramandeep Singh, Nalini Gupta, Kirti Gupta, B R Mittal, Vivek Lal
Optic disc edema may be caused by a number of conditions. A commonly ignored but important aspect is the presence of "infiltration" of disc; that may closely mimic disc edema. Disc edema, optic nerve dysfunction and a normal appearing disc in any combination may occur in infiltrative optic neuropathies. Identifying disc infiltration can aid in diagnosis of many sinister pathologies even in the absence of other specific clinical features. We describe two patients presenting with optic nerve dysfunction and infiltrated disc appearance, which on investigations were found to have underlying malignancies thereby underscoring the importance of detecting infiltrative optic neurpathies...
October 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29331255/an-automated-and-robust-image-processing-algorithm-for-glaucoma-diagnosis-from-fundus-images-using-novel-blood-vessel-tracking-and-bend-point-detection
#2
Soorya M, Ashish Issac, Malay Kishore Dutta
Glaucoma is an ocular disease which can cause irreversible blindness. The disease is currently identified using specialized equipment operated by optometrists manually. The proposed work aims to provide an efficient imaging solution which can help in automating the process of Glaucoma diagnosis using computer vision techniques from digital fundus images. The proposed method segments the optic disc using a geometrical feature based strategic framework which improves the detection accuracy and makes the algorithm invariant to illumination and noise...
February 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29328088/determination-of-the-optimum-double-pass-image-through-focus-operators
#3
Anibal G de Paul, Roberto F Sanchez, Luis A Issolio
A set of autofocus operators (AFO) are assessed for their ability to determine the optimal double-pass image as well as their potential to detect the focus lines and the disc of least confusion in astigmatic eyes. Eight AFO and three optical quality parameters (OQP) often used to analyze double-pass aerial images were considered. To quantify the discriminative power of each AFO and OQP, a maximum discrimination (MD) parameter was proposed. Double-pass images were obtained from an artificial eye with an induced astigmatism (Cylinder: -1  D, -0...
January 1, 2018: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29306778/influence-on-proliferation-and-adhesion-of-human-gingival-fibroblasts-from-different-titanium-surface-decontamination-treatments-an-in-vitro-study
#4
Cao Jie, Tong Wang, Pu Yinfei, Tang Zhihui, Meng Huanxin
OBJECTIVES: To investigate the effects of different decontamination treatments on microstructure of titanium (Ti) surface as well as proliferation and adhesion of human gingival fibroblasts (HGFs). MATERIAL AND METHODS: Ti discs with machined (M) and sand blasted, acid etched (SAE) surfaces were treated with five different decontamination treatments: (1) stainless steel curette (SSC), ultrasonic system with (2) straight carbon fiber tip (UCF) or (3) metal tip (UM), (4) rotating Ti brush (RTB), and (5) Er:YAG laser (30 mJ/pulse at 30 Hz)...
December 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29279773/automatic-cdr-estimation-for-early-glaucoma-diagnosis
#5
M A Fernandez-Granero, A Sarmiento, D Sanchez-Morillo, S Jiménez, P Alemany, I Fondón
Glaucoma is a degenerative disease that constitutes the second cause of blindness in developed countries. Although it cannot be cured, its progression can be prevented through early diagnosis. In this paper, we propose a new algorithm for automatic glaucoma diagnosis based on retinal colour images. We focus on capturing the inherent colour changes of optic disc (OD) and cup borders by computing several colour derivatives in CIE L∗a∗b∗ colour space with CIE94 colour distance. In addition, we consider spatial information retaining these colour derivatives and the original CIE L∗a∗b∗ values of the pixel and adding other characteristics such as its distance to the OD centre...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29279660/occult-optic-disc-pit-maculopathy-in-a-glaucomatous-disc
#6
Chokkahalli Krishnappa Nagesha, Pratyusha Ganne
Optic pits are congenital defects of the optic disc. Diagnosis of optic pit maculopathy is quite challenging in the absence of a clinically visible or optical coherence tomography (OCT) proven pit. One such scenario is when there is advanced glaucomatous cupping. We present a case in which OCT helped detect optic disc pit maculopathy in a 60-year-old female.
July 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/29275868/ruthenium-brachytherapy-for-uveal-melanomas-factors-affecting-the-development-of-radiation-complications
#7
Monica M Pagliara, Luca Tagliaferri, Luigi Azario, Jacopo Lenkowicz, Angela Lanza, Rosa Autorino, Carmela G Caputo, Maria A Gambacorta, Vincenzo Valentini, Maria A Blasi
PURPOSE: To investigate how treatment complications are related to dosimetric parameters after ruthenium-106 brachytherapy for uveal melanoma, in a large, clinically homogeneous population. METHODS AND MATERIALS: A retrospective review was performed to evaluate patients affected by small and medium size uveal melanoma, treated with ruthenium-106 brachytherapy from December 2006 to December 2014. We excluded tumors with posterior margin within 1 mm from the edge of the optic disc and foveola...
December 21, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29260124/utility-of-optical-coherence-tomography-angiography-in-detecting-glaucomatous-damage-in-a-uveitic-patient-with-disc-congestion-a-case-report
#8
Jiun Lap Do, Beau Sylvester, Anoush Shahidzadeh, Ruikang K Wang, Zhongdi Chu, Vivek Patel, Grace Marie Richter
Purpose: To report a case of uveitic glaucoma with a congested optic disc where optical coherence tomography angiography (OCT-A) provided diagnostic utility in assessing glaucomatous damage but optical coherence tomography (OCT) alone had limited utility. Observations: We report a case of a 33-year-old Caucasian female referred to the USC Roski Eye Institute for uncontrolled intraocular pressure (IOP) in the left eye. She was managed by an outside provider for 6 months, where her IOP ranged from 28 to 42 mm Hg in the left eye on maximally tolerated medical therapy...
December 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29258533/incidental-branch-retinal-artery-occlusion-on-optical-coherence-tomography-angiography-presenting-as-segmental-optic-atrophy-in-a-child-a-case-report
#9
Ji Hyung Choi, Hee Kyung Yang, Ji Eun Lee
BACKGROUND: Retinal artery occlusion is extremely rare in the pediatric population and most patients have risk factors. We report a case of a healthy child with segmental optic atrophy, complicated by incidental branch retinal artery occlusion (BRAO). CASE PRESENTATION: A 10-year-old boy who had a history of his mother's gestational diabetes presented with an inferonasal visual field defect in the left eye. His best-corrected visual acuities were 20/20 in both eyes (OU)...
December 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29242908/changes-in-relative-position-of-choroidal-versus-retinal-vessels-in-preterm-infants
#10
Sang Jin Kim, J Peter Campbell, Susan Ostmo, Karyn E Jonas, R V Paul Chan, Michael F Chiang
Purpose: The purpose of this study was to characterize a novel finding that relative positions of choroidal and retinal vessels change over time in preterm infants and to identify factors associated with this finding using quantitative analysis. Methods: Fundus images were obtained prospectively through a retinopathy of prematurity (ROP) cohort study. Images were excluded if choroidal vessels could not be identified. Changes in relative position of characteristic choroidal landmarks with respect to retinal vessels between two time points 5 to 7 weeks apart were measured...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29218460/a-novel-adaptive-deformable-model-for-automated-optic-disc-and-cup-segmentation-to-aid-glaucoma-diagnosis
#11
Muhammad Salman Haleem, Liangxiu Han, Jano van Hemert, Baihua Li, Alan Fleming, Louis R Pasquale, Brian J Song
This paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic glaucoma diagnosis. The novelty of our approach consists of two aspects: 1) automatic detection of initial optimum object boundary based on a Region Classification Model (RCM) in a pixel-level multidimensional feature space; 2) an Adaptive Edge Smoothing Update model (AESU) of contour points (e.g. misclassified or irregular points) based on iterative force field calculations with contours obtained from the RCM by minimising energy function (an approach that does not require predefined geometric templates to guide auto-segmentation)...
December 7, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29194196/use-of-optical-coherence-tomography-by-nonexpert-personnel-as-a-screening-approach-for-glaucoma
#12
Melissa M Liu, Chris Cho, Joan L Jefferys, Harry A Quigley, Adrienne W Scott
PURPOSE: This pilot study was conducted to assess optical coherence tomography (OCT) as a screening tool for glaucoma when used by nonexpert personnel. METHODS: This prospective case-control study included 54 patients with open-angle glaucoma and 54 age-matched comparison individuals. Optovue iVue SD-OCT imaging was performed by nonprofessional photographers on undilated patients. The sensitivity, specificity, negative predictive value, and positive predictive value of iVue scan parameters for detecting open-angle glaucoma were evaluated...
November 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29187345/wide-field-en-face-swept-source-optical-coherence-tomography-angiography-using-extended-field-imaging-in-diabetic-retinopathy
#13
Takao Hirano, Shinji Kakihara, Yuichi Toriyama, Muneeswar Gupta Nittala, Toshinori Murata, Srinivas Sadda
AIMS: To examine the feasibility of wide-field en face swept-source optical coherence tomography angiography (SS-OCTA) with extended field imaging (EFI) for evaluation of the retinal vasculature in diabetic retinopathy (DR). METHODS: This study included 37 eyes of 27 patients (age, 65±10 years; male patients, 18; female patients, 9) with DR. All patients underwent comprehensive ophthalmological examination, including OCTA and fluorescein angiography (FA). The imaging methods were compared for visible field of view, presence and extent of non-perfused areas (NPAs), presence and number of new blood vessels (NVs), vessel density (VD) and patient comfort level measured by Visual Analogue Scale...
November 29, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29180847/optic-disc-segmentation-for-glaucoma-screening-system-using-fundus-images
#14
Ahmed Almazroa, Weiwei Sun, Sami Alodhayb, Kaamran Raahemifar, Vasudevan Lakshminarayanan
Segmenting the optic disc (OD) is an important and essential step in creating a frame of reference for diagnosing optic nerve head pathologies such as glaucoma. Therefore, a reliable OD segmentation technique is necessary for automatic screening of optic nerve head abnormalities. The main contribution of this paper is in presenting a novel OD segmentation algorithm based on applying a level set method on a localized OD image. To prevent the blood vessels from interfering with the level set process, an inpainting technique was applied...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29140751/further-delineation-of-the-oculoauricular-syndrome-phenotype-a-new-family-with-a-novel-truncating-hmx1-mutation
#15
Ghada M H Abdel-Salam, Mohamed S Abdel-Hamid, Mennat I Mehrez, Ahmad M Kamal, Mohamed B Taher, Hanan H Afifi
Biallelic HMX1 mutations cause a very rare autosomal recessive genetic disorder termed as oculoauricular syndrome (OAS) because it is characterized only by the combination of eye and ear anomalies. We identified a new family bringing to three the total families reported with this disorder. Our proband presented with anteriorly protruded ears and malformed ear pinnae in association with microphthalmia, congenital cataract, microcornea, and iris and optic disc colobomata. Additionally, he had high and broad forehead with asymmetry giving a recognizable facial gestalt...
November 15, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29136839/chromisense-a-colourimetric-lab-on-a-disc-sensor-for-chromium-speciation-in-water
#16
G Duffy, I Maguire, Brendan Heery, Pauline Gers, J Ducrée, F Regan
The development of a centrifugal device for quantitative analysis of both chromium (III) and (VI) species in water is reported. ChromiSense is a colourimetric sensor system that has been applied to the measurement of chromium in spiked river water samples. For analysis, the sample is loaded into a reservoir on the disposable microfluidic disc, along with reagents. A centrifugal force is created by spinning the disc to pump liquids through microchannels, causing them to mix and react to form a coloured product...
February 1, 2018: Talanta
https://www.readbyqxmd.com/read/29124453/a-machine-learning-ensemble-classifier-for-early-prediction-of-diabetic-retinopathy
#17
Somasundaram S K, Alli P
The main complication of diabetes is Diabetic retinopathy (DR), retinal vascular disease and it leads to the blindness. Regular screening for early DR disease detection is considered as an intensive labor and resource oriented task. Therefore, automatic detection of DR diseases is performed only by using the computational technique is the great solution. An automatic method is more reliable to determine the presence of an abnormality in Fundus images (FI) but, the classification process is poorly performed...
November 9, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29122818/optical-coherence-tomographic-angiography-identifies-peripapillary-microvascular-dilation-and-focal-non-perfusion-in-giant-cell-arteritis
#18
Eric D Gaier, Aubrey L Gilbert, Dean M Cestari, John B Miller
AIMS: We set out to determine the optical coherence tomographic angiography (OCT-A) characteristics of arteritic anterior ischaemic optic neuropathy (AAION) in the context of giant cell arteritis (GCA). METHODS: This is an observational case series of four patients with AAION secondary to GCA, three with unilateral AAION and one with bilateral AAION. We reviewed the charts, fundus photography, visual fields, fluorescein angiography (FA) and OCT-A images for all patients to identify a unifying theme in a range of AAION clinical severity...
November 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29120977/use-of-a-scan-ultrasound-and-optical-coherence-tomography-to-differentiate-papilledema-from-pseudopapilledema
#19
Roberto Saenz, Han Cheng, Thomas C Prager, Laura J Frishman, Rosa A Tang
SIGNIFICANCE: Differentiating papilledema from pseudopapilledema reflecting tilted/crowded optic discs or disc drusen is critical but can be challenging. Our study suggests that spectral-domain optical coherence tomography (OCT) peripapillary retinal nerve fiber layer thickness and retrobulbar optic nerve sheath diameter (ONSD) measured by A-scan ultrasound provide useful information when differentiating the two conditions. PURPOSE: To evaluate the use of A-scan ultrasound and spectral-domain OCT retinal nerve fiber layer thickness (RNFLT) in differentiating papilledema associated with idiopathic intracranial hypertension from pseudopapilledema...
November 9, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29109901/posterior-polar-central-choroidal-dystrophy-a-case-report
#20
Funda Dikkaya, Mustafa Özsütçü, Merve Özbek, Sevil Karaman Erdur, Fevzi Şentürk
A 52-year-old male presented with a 25-year history of decreasing vision. Best corrected visual acuity was 0.3 in his right and 0.2 in his left eye. Fundoscopic examination showed bilateral symmetric atrophy of the retinal pigment epithelium and choriocapillaris in the posterior polar areas between vascular arcades and surrounding the optic disc. On fluorescein angiography, the large choroidal vessels beneath these affected regions were easily seen. Fundus autofluorescence imaging showed clearly defined hypoautofluorescent areas that corresponded to the aforementioned lesions...
October 2017: Turkish Journal of Ophthalmology
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