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https://www.readbyqxmd.com/read/28731475/unusual-metabolic-diversity-of-hyperalkaliphilic-microbial-communities-associated-with-subterranean-serpentinization-at-the-cedars
#1
Shino Suzuki, Shun'ichi Ishii, Tatsuhiko Hoshino, Amanda Rietze, Aaron Tenney, Penny L Morrill, Fumio Inagaki, J Gijs Kuenen, Kenneth H Nealson
Water from The Cedars springs that discharge from serpentinized ultramafic rocks feature highly basic (pH=~12), highly reducing (Eh<-550 mV) conditions with low ionic concentrations. These conditions make the springs exceptionally challenging for life. Here, we report the metagenomic data and recovered draft genomes from two different springs, GPS1 and BS5. GPS1, which was fed solely by a deep groundwater source within the serpentinizing system, was dominated by several bacterial taxa from the phyla OD1 ('Parcubacteria') and Chloroflexi...
July 21, 2017: ISME Journal
https://www.readbyqxmd.com/read/28729162/effect-of-3basic-life-support-training-programs-in-future-primary-school-teachers-a-quasi-experimental-design
#2
R Navarro-Patón, M Freire-Tellado, S Basanta-Camiño, R Barcala-Furelos, V Arufe-Giraldez, J E Rodriguez-Fernández
AIM: To evaluate the learning of basic life support (BLS) measures on the part of laypersons after 3different teaching programs. DESIGN: A quasi-experimental before-after study involving a non-probabilistic sample without a control group was carried out. SCOPE: Primary school teacher students from the University of Santiago (Spain). PARTICIPANTS: A total of 124 students (68.8% women and 31.2% men) aged 20-39 years (M=22...
July 17, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28719887/anesthetic-management-of-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-crs-hipec-the-importance-of-hydro-electrolytic-and-acid-basic-control
#3
Fabrício Tavares Mendonça, Marília Moreira Guimarães, Sérgio Honorato de Matos, Rúbia Garcia Dusi
JUSTIFICATION AND OBJECTIVES: Patients affected by gynecological or gastrointestinal tract neoplasms that evolve to peritoneal carcinomatosis experience a significant drop in their quality of life, high morbidity and short survival times with currently available chemotherapeutic schemes. The surgical treatment based on cytoreduction and the employment of hyperthermic intraperitoneal chemotherapy in the intra-operative period is a true challenge to anesthesiologist. CASE REPORT: A 67 years old patient diagnosed with mucinous adenocarcinoma of the Appendix associated with mucinous carcinomatosis, was submitted to cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), under general anesthesia and epidural block...
July 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28719783/making-sense-of-studies-that-claim-benefits-of-frenotomy-in-the-absence-of-classic-tongue-tie
#4
Pamela Douglas
By performing an in-depth analysis of one high profile example, this article aims to help breastfeeding support professionals understand the methodological flaws that characterize recent studies claiming to show the efficacy of frenotomy for the diagnoses of posterior tongue-tie and upper lip-tie. The example study does not address definitional confusion or control for the effects of the passage of time. It does not consider the effects of caring attention, validation, and lactation consultant support. It also does not consider the extensive research over the past three decades that has established that reflux in the first 6 months of life is benign, even though increased reflux frequency may correlate with unsettled infant behavior...
August 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28713042/implementation-of-the-universal-bls-termination-of-resuscitation-rule-in-a-rural-ems-system
#5
Matthew R Jordan, Michael F O'Keefe, David Weiss, C Wes Cubberley, Charles D MacLean, Daniel L Wolfson
BACKGROUND: Emergency Medical Services (EMS) are often the first medical providers to begin resuscitation of out-of-hospital cardiac arrest (OHCA) victims. The universal Basic Life Support Termination of Resuscitation (BLS-TOR) rule is a validated clinical prediction tool used to identify patients in which continued resuscitation efforts are futile. OBJECTIVE: The primary aim is to compare the rate of transport of OHCA cases before and after the implementation of a BLS-TOR protocol and to determine the compliance rate of EMS personnel with the new protocol in a largely volunteer, rural system...
July 13, 2017: Resuscitation
https://www.readbyqxmd.com/read/28710805/a-method-to-measure-the-absorbed-dose-of-the-thyroid-during-i-131-therapy-using-a-collar-detector-system-and-a-spect-acquisition
#6
Koen van Gils, Peter Brinks, Jules Lavalaye, Hein J Verberne, Jan B A Habraken
PURPOSE: Due to variations in biological half-life, accurate thyroid dosimetry for I-131 therapy is not trivial in clinical practice. In recent publications, systems are described to measure the uptake of I-131 in the thyroid repeatedly over time. In this work we present a method to calculate patient specific pharmacokinetics and absorbed dose using such a collar detector system (CoTI) in combination with a SPECT acquisition and a two-compartment model fit. METHODS: For three patients receiving I-131 therapy for benign thyroid conditions, the complete uptake profile is measured over a period of 15 to 25 days after administration...
July 15, 2017: Medical Physics
https://www.readbyqxmd.com/read/28702986/electromagnetic-field-in-control-tissue-regeneration-pelvic-pain-neuro-inflammation-and-modulation-of-non-neuronal-cells
#7
S E Aragona, G Mereghetti, G Gianazza, A Salsa, G Gianazza, J Lotti, A Vosa, T Lotti, E Canavesi
In scientific literature, magnetic fields are used both in basic science and clinical research. They are often used to treat pain and neuro-inflammation disorders thanks to their influence on cellular responses. Our project was born from the regenerative support that we wanted to give to those diseases characterized by neuro-inflammation, nerve lesion, muscles and tissues disorders that can transform the symptom (e.g. neuropathic pelvic pain) in disease. In this study, we examined the action of pulsed electromagnetic fields (PEMFs) on skin lesion regeneration and the repetitive trans-pelvic magnetic stimulation (rTPMS) on patients affected by incontinence and post-surgical problems, sexual dysfunction, and pelvic pain...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28701889/education-for-community-based-family-medicine-a-social-need-in-the-real-world
#8
REVIEW
Shin-Ichi Taniguchi, Daeho Park, Kazuoki Inoue, Toshihiro Hamada
One of the most critical social problems in Japan is the remarkable increase in the aging population. Elderly patients with a variety of complications and issues other than biomedical problems such as dementia and life support with nursing care have been also increasing. Ever since the Japanese economy started to decline after the economic bubble burst of 1991 and the Lehman Brothers bankruptcy in 2008, how we can resolve health problems of the elderly at a lower cost has become one of our most challenging social issues...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28699111/hla-class-ib-in-pregnancy-and-pregnancy-related-disorders
#9
REVIEW
Gry Persson, Wenna Nascimento Melsted, Line Lynge Nilsson, Thomas Vauvert F Hviid
The HLA class Ib genes, HLA-E, HLA-F, and HLA-G, were discovered long after the classical HLA class Ia genes. The elucidation of their functions had a modest beginning. However, their basic functions and involvement in pathophysiology and a range of diseases are now emerging. Although results from a range of studies support the functional roles for the HLA class Ib molecules in adult life, especially HLA-G and HLA-F have most intensively been, and were also primarily, studied in relation to reproduction and pregnancy...
July 11, 2017: Immunogenetics
https://www.readbyqxmd.com/read/28697970/cystic-fibrosis-priorities-and-progress-for-future-therapies
#10
REVIEW
Eitan Kerem
Significant improvement in the survival of patients with CF has been achieved in the last decades. The improved clinical status of the patients is mainly the result of a better understanding of the natural course of infection and inflammation in CF that has led to the implementation of strategies that increase the life expectancy and quality of life of the patients. These strategies include prompt diagnosis, timely and aggressive nutritional support, augmentation of MCC and improved mucous drainage, initiation of antimicrobial and anti-inflammatory therapy as soon as possible, early treatment of acute exacerbations, implementation of effective hygienic measures in and outside CF centers and prompt identification and treatment of CF-related complications...
June 12, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28695651/the-nurse-s-role-in-palliative-care-a-qualitative-meta-synthesis
#11
REVIEW
Ragnhild Johanne Tveit Sekse, Irene Hunskår, Sidsel Ellingsen
AIMS AND OBJECTIVES: To explore how nurses, across various health systems, describe their role in providing palliative care for patients with life-threatening illnesses. BACKGROUND: Despite the fact that nurses make up the largest group of healthcare professionals, little is known about their role in palliative care, across health services. DESIGN: A qualitative systematic review of studies. METHODS: A search was made for relevant articles, published between January 2000-June 2016...
June 8, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28694709/the-social-stigma-of-hiv-aids-society-s-role
#12
Emmanuel N Kontomanolis, Spyridon Michalopoulos, Grigorios Gkasdaris, Zacharias Fasoulakis
AIDS is a devastating and deadly disease that affects people worldwide and, like all infections, it comes without warning. Specifically, childbearing women with AIDS face constant psychological difficulties during their gestation period, even though the pregnancy itself may be normal and healthy. These women have to deal with the uncertainties and the stress that usually accompany a pregnancy, and they have to live with the reality of having a life-threatening disease; in addition to that, they also have to deal with discriminating and stigmatizing behaviors from their environment...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28694349/the-linguistic-and-interactional-factors-impacting-recognition-and-dispatch-in-emergency-calls-for-out-of-hospital-cardiac-arrest-a-mixed-method-linguistic-analysis-study-protocol
#13
Marine Riou, Stephen Ball, Teresa A Williams, Austin Whiteside, Kay L O'Halloran, Janet Bray, Gavin D Perkins, Peter Cameron, Daniel M Fatovich, Madoka Inoue, Paul Bailey, Deon Brink, Karen Smith, Phillip Della, Judith Finn
INTRODUCTION: Emergency telephone calls placed by bystanders are crucial to the recognition of out-of-hospital cardiac arrest (OHCA), fast ambulance dispatch and initiation of early basic life support. Clear and efficient communication between caller and call-taker is essential to this time-critical emergency, yet few studies have investigated the impact that linguistic factors may have on the nature of the interaction and the resulting trajectory of the call. This research aims to provide a better understanding of communication factors impacting on the accuracy and timeliness of ambulance dispatch...
July 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28693545/competence-profiles-in-undergraduate-dental-education-a-comparison-between-theory-and-reality
#14
Sebastiaan Koole, Shani Van Den Brulle, Véronique Christiaens, Wolfgang Jacquet, Jan Cosyn, Hugo De Bruyn
BACKGROUND: Competence profiles are purposed to provide a blueprint in support to develop and/or benchmark the learning outcomes of undergraduate dental curricula. This study aims to investigate whether a competence profile as proposed by academic- and clinical experts is able to represent the real clinical reality. METHODS: A questionnaire was developed including questions about gender and age, perception about required competences, and educational organisation and was distributed among Flemish dentists via email and on paper during a symposium...
July 11, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28691243/the-health-related-quality-of-life-of-patients-with-prostate-cancer-and-their-spouses-before-treatment-compared-with-the-general-population
#15
Eeva Harju, Anja Rantanen, Marja Kaunonen, Mika Helminen, Taina Isotalo, Päivi Åstedt-Kurki
AIMS: To describe the health-related quality of life (HRQOL) of patients with prostate cancer and their spouses in comparison with the Finnish general population, using the RAND 36-Item Health Survey. An additional purpose was to describe the associations between the background variables of the participants and their HRQOL. BACKGROUND: The HRQOL of patients with prostate cancer and especially their spouses at the time of diagnosis is not well known. DESIGN: A cross-sectional study...
July 9, 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28689047/major-regional-differences-in-automated-external-defibrillator-placement-and-basic-life-support-training-in-france-further-needs-for-coordinated-implementation
#16
Nicole Karam, Kumar Narayanan, Wulfran Bougouin, Nordine Benameur, Frankie Beganton, Daniel Jost, Lionel Lamhaut, Marie-Cécile Perier, Alain Cariou, David S Celermajer, Eloi Marijon, Xavier Jouven
BACKGROUND: Public Access Defibrillation (PAD) programs have emerged since mid-1990s with the aim of improving survival from Out-of-Hospital Cardiac Arrest (OHCA). The extent to which their implementation in the community differs among different areas has not been evaluated. METHODS: We carried out a 5-year prospective national evaluation of PAD programs in 51 French districts (29.3 million inhabitants), through the cumulative density of Automated External Defibrillator (AEDs) and the proportion of persons educated in Basic Life Support (BLS)...
July 5, 2017: Resuscitation
https://www.readbyqxmd.com/read/28686547/incidence-of-naloxone-redosing-in-the-age-of-the-new-opioid-epidemic
#17
Ronald Klebacher, Matthew I Harris, Navin Ariyaprakai, Ammundeep Tagore, Vince Robbins, Larissa Sophia Dudley, Robert Bauter, Susmith Koneru, Ryan D Hill, Eric Wasserman, Andrew Shanes, Mark A Merlin
STUDY OBJECTIVE: Naloxone, an opioid-antagonist deliverable by an intra-nasal route, has become widely available and utilized by law enforcement officers as well as basic life support (BLS) providers in the prehospital setting. This study aimed to determine the frequency of repeat naloxone dosing in suspected narcotic overdose (OD) patients and identify patient characteristics. METHODS: A retrospective chart review of patients over 17 years of age with suspected opioid overdose, treated with an initial intranasal (IN) dose of naloxone and subsequently managed by paramedics, was performed from April 2014 to June 2016...
July 7, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28678934/-clinical-and-social-vulnerabilities-in-crack-users-according-to-housing-status-a-multicenter-study-in-six-brazilian-state-capitals
#18
Silvia Chwartzmann Halpern, Juliana Nichterwitz Scherer, Vinicius Roglio, Sibele Faller, Anne Sordi, Felipe Ornell, Carla Dalbosco, Flavio Pechansky, Félix Kessler, Lísia von Diemen
The study had the goal to evaluate psychoactive substance use severity, violence, physical and emotional health of crack users who seeks specialized treatment in Psychosocial Care Centers for Alcohol and Drugs (CAPSad) concerning housing status. This is a multicenter cross-sectional study in six Brazilian capitals with 564 crack users categorized into two groups (1) users who have been homeless sometime in life (n = 266) and (2) individuals who have never lived on streets (n = 298). To assess the substance use severity and the characteristics of the individuals, the Addiction Severity Index, 6th version (ASI-6) was used...
July 3, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28673323/bracelet-and-self-directed-observational-therapy-for-control-of-tuberculosis-study-protocol-for-a-cluster-randomized-controlled-trial
#19
Ruixue Huang, Guofeng Ren, Jianan Hu
BACKGROUND: Approximately 80% of global tuberculosis (TB) cases occur in low-resource settings, with little opportunity for TB control. We hypothesized that the rapid increase in smartphone users and advances in digital technology would render bracelet-based applications possible; specifically, that bracelet- and self-directed observational therapy (BSDOT) can be used by patients with TB to ensure adherence to TB medication regimens and by basic village physicians to monitor care. This will ultimately allow TB to be controlled in low-resource environments...
July 4, 2017: Trials
https://www.readbyqxmd.com/read/28671060/retrospective-analysis-of-mosh-pit-related-injuries
#20
Andrew M Milsten, Joseph Tennyson, Stacy Weisberg
OBJECTIVES: Moshing is a violent form of dancing found world-wide at rock concerts, festivals, and electronic dance music events. It involves crowd surfing, shoving, and moving in a circular rotation. Moshing is a source of increased morbidity and mortality. The goal of this study was to report epidemiologic information on patient presentation rate (PPR), transport to hospital rate (TTHR), and injury patterns from patients who participated in mosh-pits. Materials and Methods Subjects were patrons from mosh-pits seeking medical care at a single venue...
July 3, 2017: Prehospital and Disaster Medicine
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