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Rhabdomyolysis: historical background, clinical, diagnostic and therapeutic features

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https://www.readbyqxmd.com/read/20298139/rhabdomyolysis-historical-background-clinical-diagnostic-and-therapeutic-features
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Gianfranco Cervellin, Ivan Comelli, Giuseppe Lippi
Rhabdomyolysis, a term used to describe the rapid breakdown of striated muscle, is characterized by rupture and necrosis of muscle fibers. This process results in the release of cell breakdown products into the bloodstream and extracellular space. Although direct muscle injury remains the most common cause of muscle injury, additional causes include hereditary enzyme disorders, drugs, toxins, endocrinopathies, malignant hyperthermia, neuroleptic malignant syndrome, heatstroke, hypothermia, electrolyte alterations, diabetic ketoacidosis and non-ketotic hyperosmolar coma, severe hypo- or hyperthyroidism and bacterial or viral infections...
June 2010: Clinical Chemistry and Laboratory Medicine: CCLM
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