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JOURNAL ARTICLE
Nora Goebel, Tomasz Stankowski, Francesco Pollari, Kambiz Hassan, Helena Jueckstock, Jens Schubel, Christian Sellin, Thorsten Zielezinski, Yacine Elhmidi, Falk-Udo Sack, Richard Feyrer, Hilmar Doerge, Harald Hausmann, Parwis Massoudy, Michael Schmoeckel, Samer Hakmi, Theodor Fischlein, Dirk Fritzsche, Ulrich F W Franke
BACKGROUND: The benefits of minimally invasive techniques in cardiac surgery remain poorly defined. We evaluated the short- and mid-term outcomes after surgical aortic valve replacement through partial upper versus complete median sternotomy (MS) in a large, German multicenter cohort. METHODS: A total of 2,929 patients underwent isolated surgical aortic valve replacement via partial upper sternotomy (PUS, n = 1,764) or MS ( n = 1,165) at nine participating heart centers between 2016 and 2020...
April 16, 2024: Thoracic and Cardiovascular Surgeon
#22
JOURNAL ARTICLE
Despoina G Sarridou, Anna Gkiouliava, Helena Argiriadou, Sophia Anastasia Mouratoglou, Jeremy B Mitchell, Christopher P Walker
INTRODUCTION: Carcinoid tumors are rare neuroendocrine tumors; about 5% of patients develop the carcinoid syndrome. We present the case of a patient with carcinoid syndrome undergoing cardiac surgery. CASE REPORT: A 74-year-old patient with carcinoid heart disease and hepatic metastases underwent double valve replacement and CABG. The patient was on octreotide therapy and antihypertensive medication. An octreotide infusion was commenced perioperatively. Pharmaceutical agents that could potentially precipitate histamine release or exacerbate catecholamine secretion and carcinoid crises were avoided...
April 16, 2024: Perfusion
#23
Ousama Jelti, Oussama El Alaoui, Adnane Lachkar, Najib Abdeljaouad, Hicham Yacoubi
Hydatidosis is a cosmopolitan anthropozoonosis common to humans and many mammals, caused by the development in the body of a dog tapeworm called Echinococcus granulosus . As accidental intermediate hosts, humans contract the infection either directly through contact with dogs or indirectly by ingesting contaminated food. They represent an epidemiological dead-end. Hydatid cysts are typically associated with the liver and lungs and, more rarely, with bones, the brain, eyes, heart, kidneys, and spleen...
March 2024: Curēus
#24
REVIEW
Shahed Tish, Ricard Corcelles
Sleeve gastrectomy (SG) has historically evolved from gastroplasty and anti-reflux procedures into one of the most commonly performed primary metabolic surgeries in the United States and worldwide. Initially initiated in the 1980s as part of the duodenal switch procedure, its standalone effectiveness and simplicity have led to increasing popularity globally. The rise in obesity rates transcends age boundaries, alarmingly affecting not only adults but also the younger demographic. This escalating trend is concerning, as it predisposes these populations to numerous future health complications, as well as highlighting the critical necessity for a safe and potent weight loss strategy...
March 28, 2024: Journal of Clinical Medicine
#25
EDITORIAL
Does Blocking the Renin-Angiotensin System Mitigate Acute Kidney Injury After Heart Transplantation?
Jacqueline Hui Fen Goh, Nian Chih Hwang
No abstract text is available yet for this article.
March 15, 2024: Journal of Cardiothoracic and Vascular Anesthesia
#26
JOURNAL ARTICLE
Sripriya Ramalingam, Parthasarathy Srinivasan
Catecholamine surge and haemodynamic derangements are normally expected during the surgery for pheochromocytoma and benign functioning adrenal tumours. This male patient in his 50s underwent radical nephrectomy for renal cell carcinoma. The patient had no comorbidities. Three hours into the surgery, during electrocauterisation of the upper pole of the kidney, the patient's blood pressure unexpectedly spiked to 180/110 mm Hg, which was immediately followed by a decrease in heart rate to 35-38 beats/min...
April 10, 2024: BMJ Case Reports
#27
MULTICENTER STUDY
Marianna Adamo, Giulio Russo, Matteo Pagnesi, Edoardo Pancaldi, Hannes Alessandrini, Martin Andreas, Luigi P Badano, Daniel Braun, Kim A Connelly, Paolo Denti, Rodrigo Estevez-Loureiro, Neil Fam, Mara Gavazzoni, Rebecca T Hahn, Claudia Harr, Joerg Hausleiter, Dominique Himbert, Daniel Kalbacher, Edwin Ho, Azeem Latib, Edith Lubos, Sebastian Ludwig, Laura Lupi, Philipp Lurz, Vanessa Monivas, Georg Nickenig, Daniela Pedicino, Giovanni Pedrazzini, Alberto Pozzoli, Denise Pires Marafon, Roberta Pastorino, Fabien Praz, Joseph Rodes-Cabau, Christian Besler, Anne Rebecca Schöber, Joachim Schofer, Andrea Scotti, Kerstin Piayda, Horst Sievert, Gilbert H L Tang, Alessandro Sticchi, David Messika-Zeitoun, Holger Thiele, Florian Schlotter, Ralph Stephan von Bardeleben, John Webb, Julien Dreyfus, Stephan Windecker, Martin Leon, Francesco Maisano, Marco Metra, Maurizio Taramasso
BACKGROUND: Data on the prognostic role of the TRI-SCORE in patients undergoing transcatheter tricuspid valve intervention (TTVI) are limited. OBJECTIVES: The aim of this study was to evaluate the performance of the TRI-SCORE in predicting outcomes of patients undergoing TTVI. METHODS: TriValve (Transcatheter Tricuspid Valve Therapies) is a large multicenter multinational registry including patients undergoing TTVI. The TRI-SCORE is a risk model recently proposed to predict in-hospital mortality after tricuspid valve surgery...
April 8, 2024: JACC. Cardiovascular Interventions
#28
JOURNAL ARTICLE
Yun Xie, Qin Guo, Bo Yang, Pan Xie, Jingxiao Zhang, Wei Lu, Claudio Ronco, Gengru Jiang
INTRODUCTION: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication associated with increased morbidity and mortality. Tissue inhibitor metalloproteinases-2 • insulin-like growth factor-binding protein 7 (TIMP-2•IGFBP7) determines tubular stress markers, which may occur prior to tubular damage. Previous studies on the use of TIMP-2•IGFBP7 for the prediction of CSA-AKI showed divergent results. Therefore, this study aimed to explore the predictive value of TIMP-2•IGFBP7 measurements for the early detection of acute kidney injury (AKI) and short-term adverse outcomes after cardiac surgery...
April 8, 2024: Cardiorenal Medicine
#29
JOURNAL ARTICLE
Andre Lamy, Glenn M Chertow, Michael Jessen, Alonso Collar, Craig D Brown, Charles A Mack, Mohamed Marzouk, Vincent Scavo, T Benton Washburn, David Savage, Julian Smith, Jayme Bennetts, Roland Assi, Christian Shults, Arman Arghami, Javed Butler, P J Devereaux, Richard Zager, Chao Wang, Steve Snapinn, Austin Browne, Jeannette Rodriguez, Stacey Ruiz, Bhupinder Singh
BACKGROUND: RBT-1 is a combination drug of stannic protoporfin (SnPP) and iron sucrose (FeS) that elicits a preconditioning response through activation of antioxidant, anti-inflammatory, and iron-scavenging pathways, as measured by heme oxygenase-1 (HO-1), interleukin-10 (IL-10), and ferritin, respectively. Our primary aim was to determine whether RBT-1 administered before surgery would safely and effectively elicit a preconditioning response in patients undergoing cardiac surgery. METHODS: This phase 2, double-blind, randomised, placebo-controlled, parallel-group, adaptive trial, conducted in 19 centres across the USA, Canada, and Australia, enrolled patients scheduled to undergo non-emergent coronary artery bypass graft (CABG) and/or heart valve surgery with cardiopulmonary bypass...
February 2024: EClinicalMedicine
#30
JOURNAL ARTICLE
Sandeep S Bains, Jeremy A Dubin, Daniel Hameed, Scott Douglas, Ruby Gilmor, Christopher G Salib, James Nace, Michael Mont, Ronald E Delanois
INTRODUCTION: Low socioeconomic status based on neighborhood of residence has been suggested to be associated with poor outcomes after total joint arthroplasty (TJA). The area deprivation index (ADI) is a scale that ranks (zero to 100) neighborhoods by increasing socioeconomic disadvantage and accounts for median income, housing type, and family structure. We sought to examine the potential differences between high (national median ADI = 47) and low ADI among TJA recipients at a single institution...
April 6, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
#31
JOURNAL ARTICLE
Sebastian Roth, René M'Pembele, Purificación Matute, Katarzyna Kotfis, Jan Larmann, Giovanna Lurati Buse
BACKGROUND: The American Heart Association (AHA) recently defined the cardiovascular-kidney-metabolic syndrome (CKM) as a new entity to address the complex interactions between heart, kidneys, and metabolism. The aim of this study was to assess the outcome impact of CKM syndrome in patients undergoing noncardiac surgery. METHODS: This is a secondary analysis of a prospective international cohort study including patients aged ≥45 years with increased cardiovascular risk undergoing noncardiac surgery...
April 5, 2024: Anesthesia and Analgesia
#32
JOURNAL ARTICLE
The Utility of the Area Deprivation Index in Assessing Complications After Total Joint Arthroplasty.
Jeremy A Dubin, Sandeep S Bains, Daniel Hameed, Rubén Monárrez, Ruby Gilmor, Zhongming Chen, James Nace, Ronald E Delanois
BACKGROUND: Vulnerable populations, including patients from a lower socioeconomic status, are at an increased risk for infection, revision surgery, mortality, and complications after total joint arthroplasty (TJA). An effective metric to quantify and compare these populations has not yet been established in the literature. The Area Deprivation Index (ADI) provides a composite area-based indicator of socioeconomic disadvantage consisting of 17 U.S. Census indicators, based on education, employment, housing quality, and poverty...
2024: JB & JS Open Access
#33
Wafaa Bzeih, Mohammad Kbar, Oussama Rihan
INTRODUCTION: Bournevile disease is a rare global condition that presents a diagnostic challenge due to its diverse multisystemic involvement. CASE PRESENTATION: This report presents the case of a 14-year-old male with a medical history of congenital single kidney, heart rate abnormalities, Bournevile disease with cognitive deficits, brain lesions, and dermatological features. The patient presented with sudden onset renal angiolipomatosis, and the diagnosis was based on specific computed tomography (CT) findings...
April 2024: Annals of Medicine and Surgery
#34
JOURNAL ARTICLE
Ahmad Assi, Mohammad Daher, Ziad Zalaquett, Marven Aoun, Bryan Youssef, Gaby Kreichati, Khalil Kharrat, Amer Sebaaly
INTRODUCTION: Intensive care unit (ICU) admissions constitute a substantial financial challenge for health care systems and patients and are linked to various potentially life-altering complications. A wide range of patient-related, surgical, and medical factors are associated with an increased risk of ICU admission following spine surgery. DISCUSSION: The most notable examples include lung, heart, and kidney disease, as well as estimated blood loss and length of surgery...
April 3, 2024: International Journal of Spine Surgery
#35
JOURNAL ARTICLE
Shawn Okpara, Tiffany Lee, Nihar Pathare, Abdullah Ghali, David Momtaz, Ugo Ihekweazu
BACKGROUND: Cardiovascular comorbidities have been identified as a significant risk factor for adverse outcomes following surgery. The purpose of this study was to investigate its prevalence and impact on postoperative outcomes, hospital metrics, and mortality in patients undergoing total knee arthroplasty (TKA). Our hypothesis was that patients with cardiovascular comorbidities would have worse outcomes, greater postoperative complication rates, and increased mortality compared to patients without cardiovascular disease...
April 2024: Clinics in Orthopedic Surgery
#36
JOURNAL ARTICLE
Rosa Melero, Beatriz Torroba-Sanz, Marian Goicoechea, Iago Sousa-Casasnovas, Jose María Barrio, Ana María García-Prieto, Patrocinio Rodriguez-Benitez, Xandra García-González, María Sanjurjo-Sáez
Cardiorenal syndrome (CRS) involves joint dysfunction of the heart and kidney. Acute forms share biochemical alterations like hyperuricaemia (HU) with tumour lysis syndrome (TLS). The mainstay treatment of acute CRS with systemic overload is diuretics, but rasburicase is used in TLS to prevent and treat hyperuricaemia. An observational, retrospective study was performed to assess the effectiveness and safety of a single dose of rasburicase in hospitalized patients with cardiorenal syndrome, worsening renal function and uric acid levels above 9 mg/dL...
March 15, 2024: International Journal of Molecular Sciences
#37
JOURNAL ARTICLE
Federica Baccanelli, Giovanni Albano, Alfonso Carrara, Matteo Parrinello, Claudio Roscitano, Maurizio Cecconi, Piersilvio Gerometta, Ascanio Graniero, Alfonso Agnino, Lorenzo Peluso
Background : Postoperative myocardial injury, as detected by an elevated concentration of high-sensitivity cardiac troponin I (hs-cTnI), is a common complication in cardiac surgery that may be linked to mortality. The primary aim of this study was to assess the risk factors associated with increased myocardial injury in patients undergoing minimally invasive mitral valve surgery. Methods : In this retrospective monocentric cohort study, we analyzed all patients who underwent elective minimally invasive mitral valve surgery between January 2019 and December 2022 and were subsequently admitted to our intensive care unit...
March 10, 2024: Journal of Clinical Medicine
#38
JOURNAL ARTICLE
Paige E Condit, Daniel P Gorski, Michael R Lasarev, Awni M Al-Subu, Matthew W Harer
(1) Background: Near-infrared spectroscopy (NIRS) is a noninvasive tool frequently used during cardiac surgery and postoperatively in the cardiac intensive care unit to monitor regional tissue oxygen saturation. A relationship between trends of intraoperative renal oxygenation and the risk of developing cardiac surgery-associated acute kidney injury (AKI) post-operatively has not yet been established in the neonatal population. The objective of this study is to evaluate the relationship of cerebral and renal oxygenation during cardiopulmonary bypass with cardiac surgery-associated AKI in the first 72 h post-operation in neonates < 30 days of age...
March 7, 2024: Children
#39
Jan P Kleinjan, Justin Blom, André P van Beek, Hjalmar R Bouma, Peter R van Dijk
Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are a new class of drugs that have been proven beneficial in the management of diabetes, chronic kidney disease, and heart failure and in the mitigation of cardiovascular risk. The benefits of SGLT2i therapy have led to the rapid adoption of these drugs in clinical guidelines. Since the introduction of these drugs, concerns have arisen, as diabetic ketoacidosis (DKA) unexpectedly occurred in patients treated with SGLT2i. DKA is an infrequent but serious complication of SGLT2i therapy, and is potentially preventable...
March 13, 2024: Metabolites
#40
JOURNAL ARTICLE
Sevag Demirjian, Faisal Bakaeen, W H Wilson Tang, Chase Donaldson, Jon Taliercio, Anne Huml, Crystal A Gadegbeku, A Marc Gillinov, Steven Insler
OBJECTIVES: Examine the: 1) relative role of hemodynamic determinants of acute kidney injury (AKI) obtained in the immediate postcardiac surgery setting compared with established risk factors, 2) their predictive value, and 3) extent mediation via central venous pressure (CVP) and mean arterial pressure (MAP). DESIGN: Retrospective observational study. The main outcome of the study was moderate to severe AKI, per kidney disease: improving global outcomes, within 14 days of surgery...
April 2024: Critical care explorations
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