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https://www.readbyqxmd.com/read/28805725/signal-to-noise-ratio-enhancement-based-on-empirical-mode-decomposition-in-phase-sensitive-optical-time-domain-reflectometry-systems
#1
Zengguang Qin, Hui Chen, Jun Chang
We propose a novel denoising method based on empirical mode decomposition (EMD) to improve the signal-to-noise ratio (SNR) for vibration sensing in phase-sensitive optical time domain reflectometry (φ-OTDR) systems. Raw Rayleigh backscattering traces are decomposed into a series of intrinsic mode functions (IMFs) and a residual component using an EMD algorithm. High frequency noise is eliminated by removing several IMFs at the position without vibration selected by the Pearson correlation coefficient (PCC)...
August 14, 2017: Sensors
https://www.readbyqxmd.com/read/28803996/perioperative-hemodynamics-and-outcomes-of-patients-on-metyrosine-undergoing-resection-of-pheochromocytoma-or-paraganglioma
#2
James J Butz, Toby N Weingarten, Alexandre N Cavalcante, Irina Bancos, William F Young, Travis J McKenzie, Darrell R Schroeder, David P Martin, Juraj Sprung
INTRODUCTION: To describe outcomes of patients with metyrosine (MET) pretreatment for abdominal surgical resection of pheochromocytoma or paraganglioma (PCC/PGL) compared with patients who had phenoxybenzamine (PBZ) pretreatment. METHODS: Retrospective review of perioperative outcomes for PCC/PGL patients treated with MET and propensity-matched comparison of MET and PBZ (MET + PBZ) with PBZ alone. RESULTS: MET preparation was given in 63 cases (26 laparoscopic and 37 open, of which 55 also received PBZ)...
August 10, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28803467/not-gate-genetic-circuits-to-control-gene-expression-in-cyanobacteria
#3
Arnaud Taton, Amy T Ma, Mizuho Ota, Susan Golden, James W Golden
To downregulate gene expression in cyanobacteria, we constructed NOT gate genetic circuits using orthogonal promoters and their cognate repressors regulated translationally by synthetic riboswitches. Four NOT gates were tested and characterized in five cyanobacterial strains using fluorescent reporter-gene assays. In comparison to alternative systems used to downregulate gene expression in cyanobacteria, these NOT gates performed well, reducing YFP reporter expression by 4 to 50-fold. We further evaluated these NOT gates by controlling the expression of the ftsZ gene, which encodes a prokaryotic tubulin homolog that is required for cell division and is essential for Synechococcus elongatus PCC 7942...
August 14, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28800320/ensemble-methods-integrated-with-mirna-expression-data-for-predicting-mirna-targets-in-stomach-adenocarcinoma
#4
Guang-Wei Liu, Zhao-Min Qin, Qin-Hai Shen
OBJECTIVE: It is crucially important to discover the relationships between genes and microRNAs (miRNAs) in cancer. Thus, we proposed a combined bioinformatics method integrating Pearson's correlation coefficient (PCC), Lasso, and causal inference method (IDA) to identify the potential miRNA targets for stomach adenocarcinoma (STAD) using Borda count election. MATERIALS AND METHODS: Firstly, the ensemble method integrating PCC, IDA, and Lasso was used to predict miRNA targets...
July 31, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28795265/the-stress-induced-scp-hlip-family-of-small-light-harvesting-like-proteins-scpabcde-protects-photosystem-ii-from-photoinhibitory-damages-in-the-cyanobacterium-synechocystis-sp-pcc-6803
#5
Tania Tibiletti, Ateeq Ur Rehman, Imre Vass, Christiane Funk
Small CAB-like proteins (SCPs) are single-helix light-harvesting-like proteins found in all organisms performing oxygenic photosynthesis. We investigated the effect of growth in moderate salt stress on these stress-induced proteins in the cyanobacterium Synechocystis sp. PCC 6803 depleted of Photosystem I (PSI), which expresses SCPs constitutively, and compared these cells with a PSI-less/ScpABCDE(-) mutant. SCPs, by stabilizing chlorophyll-binding proteins and Photosystem II (PSII) assembly, protect PSII from photoinhibitory damages, and in their absence electrons accumulate and will lead to ROS formation...
August 9, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28794498/analysis-of-inflammatory-cytokine-and-tlr-expression-levels-in-type-2-diabetes-with-complications
#6
Saket Gupta, Ashwini Maratha, Jakub Siednienko, Anandan Natarajan, Thusitha Gajanayake, Shu Hoashi, Sinéad Miggin
The pathogenesis and complications of type 2 diabetes (T2DM) are closely linked with defective glucose metabolism, obesity, cardiovascular disease and an inability to mount an effective immune response to certain pathogenic organisms. Perturbations in key innate immune receptors known as Toll-like receptors (TLRs) and inflammatory mediators such as IL-6, TNFα and IL-1β have been linked with T2DM. Herein, we sought to establish whether patients with T2DM and underlying complications exhibit perturbations in cytokine and TLR expression...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28789610/management-of-refractory-bleeding-post-cardiopulmonary-bypass-in-an-acute-heparin-induced-thrombocytopenia-type-ii-renal-failure-patient-who-underwent-urgent-cardiac-surgery-with-bivalirudin-angiox-%C3%A2-anticoagulation
#7
Kimberly Hassen, Maria R Maccaroni, Haytham Sabry, Smitangshu Mukherjee, Shankari Serumadar, Inderpaul Birdi
Acute heparin-induced thrombocytopenia (HIT) patients present myriad anticoagulation management challenges in clinical settings where unfractionated heparin (UFH) is the traditional drug of choice. UFH use in cardiac surgery is a known entity that has been subject to rigorous research. Research has, thus, led to its unparalleled use and the development of well-established protocols for cardiac surgery. In comparison to UFH, bivalirudin use for acute HIT patients requiring urgent cardiac surgery with cardiopulmonary bypass (CPB) is still in its infancy...
August 1, 2017: Perfusion
https://www.readbyqxmd.com/read/28776147/looming-threats-and-animacy-reduced-responsiveness-in-youth-with-disrupted-behavior-disorders
#8
Stuart F White, Laura C Thornton, Joseph Leshin, Roberta Clanton, Stephen Sinclair, Dionne Coker-Appiah, Harma Meffert, Soonjo Hwang, James R Blair
Theoretical models have implicated amygdala dysfunction in the development of Disruptive Behavior Disorders (DBDs; Conduct Disorder/Oppositional Defiant Disorder). Amygdala dysfunction impacts valence evaluation/response selection and emotion attention in youth with DBDs, particularly in those with elevated callous-unemotional (CU) traits. However, amygdala responsiveness during social cognition and the responsiveness of the acute threat circuitry (amygdala/periaqueductal gray) in youth with DBDs have been less well-examined, particularly with reference to CU traits...
August 3, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28773961/polymer-cement-composites-containing-waste-perlite-powder
#9
Paweł Łukowski
Polymer-cement composites (PCCs) are materials in which the polymer and mineral binder create an interpenetrating network and co-operate, significantly improving the performance of the material. On the other hand, the need for the utilization of waste materials is a demand of sustainable construction. Various mineral powders, such as fly ash or blast-furnace slag, are successfully used for the production of cement and concrete. This paper deals with the use of perlite powder, which is a burdensome waste from the process of thermal expansion of the raw perlite, as a component of PCCs...
October 17, 2016: Materials
https://www.readbyqxmd.com/read/28769570/reversal-of-direct-oral-anticoagulants
#10
REVIEW
Mosaad Almegren
Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a major concern in clinical practice. After DOACs were introduced and became widely used as an alternative for vitamin K antagonists in the management of venous thromboembolism and nonvalvular atrial fibrillation, the need for effective reversal agents has increased, particularly for life-threatening bleeding episodes related to DOACs or to reverse medication effects during urgent interventions...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28764614/quantitative-evaluation-of-arteriovenous-malformation-hemodynamic-changes-after-endovascular-treatment-using-parametric-color-coding-a-case-series-study
#11
Rodrigo Rivera, Juan G Sordo, Daniel Echeverria, Lautaro Badilla, Camila Pinto, Catalina Merino-Osorio
Background Brain arteriovenous malformations (AVMs) are complex vascular lesions. Endovascular treatment results are usually measured by calculating the volume reduction of the lesions. Nevertheless, vascular flow quantification seems a more physiologically accurate way of measuring endovascular results. We evaluated the use of parametric color coding (PCC) with digital subtraction angiography (DSA), in order to determine the feasibility of PCC to detect and measure the impact of AVM endovascular treatment-induced changes using real-time hemodynamic parameters...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28763307/comparison-of-3-factor-versus-4-factor-prothrombin-complex-concentrate-with-regard-to-warfarin-reversal-blood-product-use-and-costs
#12
Jessica DeAngelo, Daniel Jarrell, Richard Cosgrove, James Camamo, Christopher Edwards, Asad E Patanwala
BACKGROUND: Prothrombin complex concentrates (PCCs) are drug products containing varying amounts of vitamin K-dependent coagulation factors II, VII, IX, and X. The evidence comparing 3-factor PCC (3-PCC) versus 4-factor PCC (4-PCC) for warfarin reversal is conflicting. It has been hypothesized that 3-PCC may be less effective than 4-PCC because of relatively lower factor VII content. STUDY QUESTION: The primary objective of this study was to compare international normalized ratio (INR) reversal between 3-PCC and 4-factor PCC (4-PCC) in warfarin-treated patients...
July 26, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28762722/posttranslational-modification-of-heme-b-in-a-bacterial-peroxidase-the-role-of-heme-to-protein-ester-bonds-in-ligand-binding-and-catalysis
#13
Andrea Nicolussi, Markus Auer, Julia Weissensteiner, Georg Schuetz, Sonja Katz, Daniel Maresch, Stefan Hofbauer, Marzia Bellei, Gianantonio Battistuzzi, Paul G Furtmüller, Christian Obinger
The existence of covalent heme to protein bonds is the most striking structural feature of mammalian peroxidases including myeloperoxidase (MPO) and lactoperoxidase (LPO). These autocatalytic posttranslational modifications (PTMs) were shown to strongly influence the biophysical and biochemical properties of these oxidoreductases. Recently, we reported the occurrence of stable LPO-like counterparts with two heme to protein ester linkages in bacteria. The present study focuses on the model wild-type peroxidase from the cyanobacterium Lyngbya sp...
August 1, 2017: Biochemistry
https://www.readbyqxmd.com/read/28760072/omega-3-fatty-acid-attenuates-oxidative-stress-in-cerebral-cortex-cerebellum-and-hippocampus-tissue-and-improves-neurobehavioral-activity-in-chronic-lead-induced-neurotoxicity
#14
Pramod Kumar Singh, Manish Kumar Singh, Rajesh Singh Yadav, Rajendra Nath, Anju Mehrotra, Akash Rawat, Rakesh Kumar Dixit
OBJECTIVES: In view of the increasing risk of lead on human health, the present study has been carried out to investigate the neuroprotective effect of omega-3 fatty acid on chronic lead-induced neurotoxicity and behavioral impairment in rats. METHODS: Different neurobehavioral parameters, biochemical assays, and histopathological analyses in brain regions of rats were conducted. RESULTS: Rats exposed to different doses of lead (lead acetate 2...
August 1, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28759780/neural-correlates-of-evaluating-self-and-close-other-in-physical-academic-and-prosocial-domains
#15
R van der Cruijsen, S Peters, E A Crone
Behavioral studies showed that self-concept can be distinguished into different domains, but few neuroimaging studies have investigated either domain-specific or valence-specific activity. Here, we investigated whether evaluating self- and mother-traits in three domains (physical, academic, prosocial) relies on similar or distinct brain regions. Additionally, we explored the topical discussion in the literature on whether vmPFC activity during self-evaluations is induced by valence or importance of traits. Participants evaluated themselves and their mothers on positive and negative traits in three domains...
July 28, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28755150/picosecond-excitation-energy-transfer-of-allophycocyanin-studied-in-solution-and-in-crystals
#16
Reza Ranjbar Choubeh, Ravi R Sonani, Datta Madamwar, Paul C Struik, Arjen N Bader, Bruno Robert, Herbert van Amerongen
Cyanobacteria perform photosynthesis with the use of large light-harvesting antennae called phycobilisomes (PBSs). These hemispherical PBSs contain hundreds of open-chain tetrapyrrole chromophores bound to different peptides, providing an arrangement in which excitation energy is funnelled towards the PBS core from where it can be transferred to photosystem I and/or photosystem II. In the PBS core, many allophycocyanin (APC) trimers are present, red-light-absorbing phycobiliproteins that covalently bind phycocyanobilin (PCB) chromophores...
July 28, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28754517/does-person-centered-care-improve-residents-satisfaction-with-nursing-home-quality
#17
Judith L Poey, Linda Hermer, Laci Cornelison, Migette L Kaup, Patrick Drake, Robyn I Stone, Gayle Doll
OBJECTIVE: Person-centered care (PCC) is meant to enhance nursing home residents' quality of life (QOL). Including residents' perspectives is critical to determining whether PCC is meeting residents' needs and desires. This study examines whether PCC practices promote satisfaction with QOL and quality of care and services (QOC and QOS) among nursing home residents. DESIGN: A longitudinal, retrospective cohort study using an in-person survey. SETTING: Three hundred twenty nursing homes in Kansas enrolled or not enrolled in a pay-for-performance program, Promoting Excellent Alternatives in Kansas (PEAK 2...
July 25, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28752085/review-of-pediatric-pheochromocytoma-and-paraganglioma
#18
REVIEW
Reshma Bholah, Timothy Edward Bunchman
Pheochromocytoma (PCC) and paraganglioma (PGL) are rare chromaffin cell tumors which secrete catecholamines and form part of the family of neuroendocrine tumors. Although a rare cause of secondary hypertension in pediatrics, the presentation of hypertension in these patients is characteristic, and treatment is definitive. The gold standard for diagnosis is via measurement of plasma free metanephrines, with imaging studies performed for localization, identification of metastatic lesions and for surgical resection...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28751211/microbial-f-type-lectin-domains-with-affinity-for-blood-group-antigens
#19
Sonal Mahajan, Aasawari Khairnar, Ritika Bishnoi, T N C Ramya
F-type lectins are fucose binding lectins with characteristic fucose binding and calcium binding motifs. Although they occur with a selective distribution in viruses, prokaryotes and eukaryotes, most biochemical studies have focused on vertebrate F-type lectins. Recently, using sensitive bioinformatics search techniques on the non-redundant database, we had identified many microbial F-type lectin domains with diverse domain organizations. We report here the biochemical characterization of F-type lectin domains from Cyanobium sp...
July 24, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28745633/determination-of-the-glycogen-content-in-cyanobacteria
#20
Alice De Porcellinis, Niels-Ulrik Frigaard, Yumiko Sakuragi
Cyanobacteria accumulate glycogen as a major intracellular carbon and energy storage during photosynthesis. Recent developments in research have highlighted complex mechanisms of glycogen metabolism, including the diel cycle of biosynthesis and catabolism, redox regulation, and the involvement of non-coding RNA. At the same time, efforts are being made to redirect carbon from glycogen to desirable products in genetically engineered cyanobacteria to enhance product yields. Several methods are used to determine the glycogen contents in cyanobacteria, with variable accuracies and technical complexities...
July 17, 2017: Journal of Visualized Experiments: JoVE
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