Chau-Minh Phan, Vivian Wy Chan, Elizabeth Drolle, Alex Hui, William Ngo, Susmita Bose, Amanda Shows, Shuang Liang, Vinay Sharma, Lakshman Subbaraman, Ying Zheng, Xinfeng Shi, James Wu, Lyndon Jones
PURPOSE: To evaluate the in vitro wettability and coefficient of friction of a novel amphiphilic polymeric surfactant (APS), poly(oxyethylene)-co-poly(oxybutylene) (PEO-PBO) releasing silicone hydrogel (SiHy) contact lens material (serafilcon A), compared to other reusable SiHy lens materials. METHODS: The release of fluorescently-labelled nitrobenzoxadiazole (NBD)-PEO-PBO was evaluated from serafilcon A over 7 days in a vial. The wettability and coefficient of friction of serafilcon A and three contemporary SiHy contact lens materials (senofilcon A; samfilcon A; comfilcon A) were evaluated using an in vitro blink model over their recommended wearing period; t = 0, 1, 7, 14 days for all lens types and t = 30 days for samfilcon A and comfilcon A (n = 4)...
February 29, 2024: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association