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Post stroke depression

Yan-Ping Zheng, Fu-Xi Wang, De-Qiang Zhao, Yan-Qing Wang, Zi-Wei Zhao, Zhan-Wen Wang, Jun Liu, Jun Wang, Ping Luan
Electroencephalography is a sensitive indicator for measuring brain condition, and can reflect early changes in brain function and severity of cerebral ischemia. However, it is not yet known whether electroencephalography can predict development of post-cerebral infarction depression. A total of 321 patients with ischemic stroke underwent electroencephalography and Hamilton Depression Rating Scale assessment to analyze the relationship between electroencephalography and post-cerebral infarction depression. Our results show that electroencephalograms of ischemic stroke patients with depression exhibit low-amplitude alpha activity and slow theta activity...
February 2018: Neural Regeneration Research
Alexandra L Terrill, Maija Reblin, Justin J MacKenzie, Beth Cardell, Jackie Einerson, Cynthia A Berg, Jennifer J Majersik, Lorie Richards
OBJECTIVE: Stroke provides challenges for survivors and partner caregivers. Stroke survivors and caregivers are interconnected in their emotional health, including depression, a common stroke sequelae. The purpose of this study was to develop and test the feasibility of a dyadic positive psychology-based intervention (PPI) for couples coping poststroke. DESIGN: Community-dwelling couples consisted of 1 partner who had a stroke ≥6 months ago and a cohabiting partner caregiver...
February 2018: Rehabilitation Psychology
Natalia Egorova, Toby Cumming, Chris Shirbin, Michele Veldsman, Emilio Werden, Amy Brodtmann
Around one-third of people develop depression following ischaemic stroke, yet the underlying mechanisms are poorly understood. Post-stroke depression has been linked to frontal infarcts, mainly lesions in the left dorsolateral prefrontal cortex (DLPFC). But depression is a network disorder that cannot be fully characterised through lesion-symptom mapping. Researchers of depression in non-stroke populations have successfully tapped into the cognitive control network (CCN) using the bilateral DLPFC as a seed, and found that CCN resting-state connectivity is reduced in even mildly depressed subjects, compared to healthy controls...
March 9, 2018: Translational Psychiatry
H J Arwert, J J L Meesters, J Boiten, F Balk, R Wolterbeek, T P M Vliet Vlieland
OBJECTIVES: To ascertain the prevalence of depressive mood and its determinants in the chronic phase after stroke. DESIGN: 576 consecutive patients were invited to participate 2-5 years after hospitalization for a first-ever stroke. Stroke characteristics at hospitalization were collected retrospectively from medical records. Patients and their caregivers completed questionnaires on depression (Hospital Anxiety and Depression Scale; HADS), socio-demographic characteristics, healthcare usage, daily activities, Quality of Life and caregiver strain...
March 5, 2018: American Journal of Physical Medicine & Rehabilitation
Mariëlle W A van Rijsbergen, Ruth E Mark, Willem J Kop, Paul L M de Kort, Margriet M Sitskoorn
Subjective Cognitive Complaints (SCC) are common after stroke and adversely affect quality of life. In the present study, we determined the associations of depression, anxiety, perceived stress and fatigue with post-stroke SCC, and whether these associations were independent of objective cognitive functioning, stroke characteristics and individual differences in personality traits and coping styles. Using a cross-sectional design, SCC and psychological measures were obtained in 208 patients (mean 3.3 ± 0...
March 4, 2018: Neuropsychological Rehabilitation
Munira Essat, Ahmed Aber, Patrick Phillips, Edith Poku, Helen Buckley Woods, Aoife Howard, Simon Palfreyman, Eva Kaltenthaler, Georgina Jones, Jonathan Michaels
OBJECTIVE: Patient-reported outcome measures (PROMs) provide a way to measure the impact of a disease and its associated treatments on the quality of life from the patients' perspective. The aim of this review was to identify PROMs that have been developed and/or validated in patients with carotid artery stenosis (CAS) undergoing revascularisation and to assess their psychometric properties and examine suitability for research and clinical use. METHODS: Eight electronic databases including MEDLINE and CINAHL were searched using a two-stage search approach to identify studies reporting the development and/or validation of relevant PROMs in patients with CAS undergoing revascularisation...
February 28, 2018: Annals of Vascular Surgery
Wa Cai, Wen Ma, Guan-Tao Wang, Wei-Dong Shen
BACKGROUND: Poststroke depression is closely related to increased mortality in stroke patients. Compared with antidepressants, electroacupuncture (EA) treatment for poststroke depression (PSD) has relatively more stable effectiveness and can reduce side effects. This trial is designed to provide solid evidence for the efficacy and safety of EA treatment for patients with PSD. METHODS/DESIGN: This ongoing study is a single-blind, single-center, parallel group, randomized controlled trial...
March 2, 2018: Trials
Jeffrey Guina, Cathryn Guina
While post-stroke depression (PSD) is a common sequelae of stroke, many stroke survivors also have expressive aphasia (i.e., the inability to produce spoken or written language), which limits or prevents treating depression with talk psychotherapy. Unlike most psychotherapy modalities, eye movement desensitization and reprocessing (EMDR) does not require extensive verbal communication to therapists, which might make EMDR an ideal treatment modality for aphasic patients with mental health concerns. The authors present the first known case reporting EMDR in aphasia, describing the treatment of a 50-year-old woman with a history of depression following a left middle cerebral artery stroke...
February 1, 2018: Innovations in Clinical Neuroscience
Zhihua Liu, Yan Cai, Jincai He
Purpose: Although previous studies have investigated oxidative stress biomarkers in association with depression in non-stroke subjects, the association between oxidative deoxyribonucleic acid damage and post-stroke depression (PSD) remains unelucidated. Patients and methods: Two hundred forty-one first-ever ischemic stroke patients were consecutively recruited within the first 24 h of stroke onset and were followed up at 1 month. Serum 8-hydroxy-2'-deoxyguanosine (8-OHdG) and catalase (CAT) levels were measured within 24 h of admission using a commercially available enzyme-linked immunosorbent assay...
2018: Neuropsychiatric Disease and Treatment
Emily K Simpson, Narissa M Ramirez, Brittany Branstetter, Aileen Reed, Evan Lines
Following a stroke, depression and anxiety may negatively affect recovery and decrease quality of life. Occupational therapy (OT) practitioners are distinctly qualified to address both the physical and psychosocial sequelae of a stroke, including clients' mental and emotional health. This study explored the ways in which OT practitioners address the mental health needs of clients post stroke. A sequential explanatory mixed-methods design was used to collect both survey and focus group data. In all, 754 OT practitioners across the United States completed an online survey, and 10 practitioners participated in focus groups...
March 1, 2018: OTJR: Occupation, Participation and Health
Margaret A French, Susanne M Morton, Ryan T Pohlig, Darcy S Reisman
Background A single nucleotide polymorphism, Val66Met, in the Brain Derived Neurotrophic Factor (BDNF) gene has been studied for its role in recovery following stroke. Despite this work, the role of BDNF genotype on long-term recovery is unclear. Additionally, no study has examined its impact on functional mobility. As a result, the purpose of this study was to examine the relationship between BDNF genotype and functional mobility in chronic stroke survivors by first accounting for factors related to the Val66Met polymorphism and post-stroke recovery...
February 25, 2018: Topics in Stroke Rehabilitation
Eun-Song Kim, Ju-Wan Kim, Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Joon-Tae Kim, Man-Seok Park, Ki-Hyun Cho, Jae-Min Kim
OBJECTIVE: Stroke is associated with significant long-term morbidity and poor quality of life (QOL). Depression is one of the most common complications after stroke and has been associated with QOL cross-sectionally. We investigated the longitudinal impact of depression in the acute phase of stroke on QOL 1 year after stroke. METHODS: In total, 423 patients were evaluated 2 weeks after stroke, and 288 (68%) were followed 1 year later. QOL was assessed using the World Health Organization Quality of Life-Abbreviated form (WHOQOL-BREF) at baseline and follow-up...
February 2018: Psychiatry Investigation
Yan Sun, Xia Xu, Jinping Zhang, Yuanyuan Chen
BACKGROUND: Depression is a common mental disorder. Chai Hu Shu Gan San, a traditional Chinese medicine, is used to treat depression empirically. We present a systematic review and meta-analysis of the therapeutic efficacy and safety of Chai Hu Shu Gan San in treating depression. METHODS: Several databases, including PubMed, China National Knowledge Internet, Wanfang, Chongqing VIP, and the Cochrane library, were systematically searched from their date of foundation to January 1, 2017...
February 17, 2018: BMC Complementary and Alternative Medicine
Argye E Hillis, Yuan Ye Beh, Rajani Sebastian, Bonnie Breining, Donna C Tippett, Amy Wright, Sadhvi Saxena, Chris Rorden, Leonardo Bonilha, Alexandra Basilakos, Grigori Yourganov, Julius Fridriksson
OBJECTIVE: Many stroke patients show remarkable recovery of language after initial severe impairment, but it is difficult to predict which patients will show good recovery. We aimed to identify patient and lesion characteristics that together predict the best naming outcome in four studies. METHODS: We report two longitudinal studies that identified two variables at onset that were strongly associated with good recovery of naming (the most common residual deficit in aphasia) in the first six months after stroke: damage to left posterior superior temporal gyrus (pSTG) and/or superior longitudinal fasciculus/arcuate fasciculus (SLF/AF) and selective serotonin reuptake inhibitor (SSRI) use...
February 16, 2018: Annals of Neurology
Katherine S McGilton, Riva Sorin-Peters, Elizabeth Rochon, Veronique Boscart, Mary Fox, Charlene H Chu, Steven C Stewart, Souraya Sidani
PURPOSE OF THE STUDY: This small scale study examined the influence of an interprofessional (IP) evidence based patient-centered communication intervention (PCCI), delivered by trained nurses in collaboration with Speech Language Pathologists, on patient outcomes in an active stroke rehabilitation setting. DESIGN AND METHODS: The setting constraints imposed the use of a single-group pretest and post-test design to determine the influence of the intervention on patient outcomes...
February 2018: Applied Nursing Research: ANR
Grace M Turner, Ruth Backman, Christel McMullan, Jonathan Mathers, Tom Marshall, Melanie Calvert
Plain English summary: What is the problem and why is this important? Mini-strokes are similar to full strokes, but symptoms last less than 24 h. Many people (up to 70%) have long-term problems after a mini-stroke, such as anxiety; depression; problems with brain functioning (like memory loss); and fatigue (feeling tired). However, the current healthcare pathway only focuses on preventing another stroke and care for other long-term problems is not routinely given. Without proper treatment, people with long-term problems after a mini-stroke could have worse quality of life and may find it difficult to return to work and their social activities...
2018: Research Involvement and Engagement
Fu-Ying Zhao, Ying-Ying Yue, Lei Li, Sen-Yang Lang, Ming-Wei Wang, Xiang-Dong Du, Yun-Long Deng, Ai-Qin Wu, Yong-Gui Yuan
Post-stroke depression (PSD) is a very common complication that leads to increased physical disability, poor functional outcome, and higher mortality. Therefore, early detection and treatment are very important. Since there are currently no specific guidelines for this disorder in China, the purpose of this study was to develop PSD guidelines and provide suggestions for clinicians and related workers.
February 1, 2018: Revista Brasileira de Psiquiatria
Han-Cheng Qiu, Hui-Zhen Liu, Xuemei Li, Xianwei Zeng, Ji-Zong Zhao
OBJECTIVE: Previous studies suggested that insulin resistance (IR) may be a significant causal risk factor for cardiovascular events and depression independent of other risk factors. In this prospective, we assess the value of Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) at admission to predict post-stroke depression (PSD) later developed at 3 months follow-up. METHODS: This prospective, multicenter cohort study was conducted from January 2015 through December 2016 in China...
February 1, 2018: Journal of Affective Disorders
Peiyao Zhang, Jing Wang, Qin Xu, Zheng Song, Jianping Dai, Jun Wang
OBJECTIVE: In previous studies, post-stroke depression (PSD) was found to be related to stroke characteristics as well as social and psychological factors. This study identified altered functional connectivity (FC) in patients with PSD at the subacute phase in three brain networks: default mood network (DMN), cognitive control network (CCN), and affective network (AN). The correlation between FC and the severity of PSD was investigated. MATERIALS AND METHODS: Resting-state functional magnetic resonance image (rs-fMRI) was performed on 26 PSD patients (6 females), 24 stroke patients without depression (5 females), and 24 age-matched normal controls (6 females) all aged 40-75 years...
January 4, 2018: European Journal of Radiology
Liming Dong, Brisa N Sánchez, Lesli E Skolarus, Lewis B Morgenstern, Lynda D Lisabeth
BACKGROUND: Little is known about ethnic differences in poststroke depression (PSD) in the United States. This study aims to estimate the prevalence of PSD at 90 days after first-ever stroke and to examine ethnic differences in the prevalence between Mexican Americans (MAs) and non-Hispanic whites (NHWs). METHODS AND RESULTS: Stroke cases from 2011 to 2015 were identified from the BASIC project (Brain Attack Surveillance in Corpus Christi)-a population-based stroke surveillance study in south Texas...
February 2018: Circulation. Cardiovascular Quality and Outcomes
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