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https://www.readbyqxmd.com/read/27845416/psychiatric-and-neurological-disorders-are-associated-with-bullous-pemphigoid-a-nationwide-finnish-care-register-study
#1
Anna-Kaisa Försti, Jari Jokelainen, Hanna Ansakorpi, Allan Seppänen, Kari Majamaa, Markku Timonen, Kaisa Tasanen
Bullous pemphigoid (BP) is an autoimmune blistering skin disease with increasing incidence. BP is associated with neurological disorders, but it has not been established, what subtypes of dementia and stroke are associated with BP, and what is the temporal relation between these diseases. Also, the association between BP and psychiatric disorders is controversial. We conducted a retrospective nationwide study, using the Finnish Care Register for Health Care diagnoses between 1987 and 2013. The study population of 4524 BP patients were compared with 66138 patients with basocellular carcinoma (BCC), neurological and psychiatric comorbid disorders were evaluated for both groups, and associations were estimated by Cox regression and logistic regression analyses...
November 15, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27581366/detection-of-a-second-malignancy-in-prostate-cancer-patients-by-using-18-f-choline-pet-ct-a-case-series
#2
Martina Sollini, Francesco Pasqualetti, Marzio Perri, Gabriele Coraggio, Paolo Castellucci, Massimo Roncali, Roberto Boni, Elena Lazzeri, Maria Galeandro, Fabiola Paiar, Annibale Versari, Paola Anna Erba
BACKGROUND: The role of radiolabeled choline (Cho) in patients with biochemical recurrence after radical treatment for prostate cancer (PCa) is well established. Its widespread clinical use has prompted the depiction of incidentalomas, unusual sites of metastatic lesions, as well as false positive and negative cases. We reported a series of patients affected by biochemical recurrence of PCa imaged by [(18)F]Cho positron emission tomography/computed tomography (PET/CT) which resulted suspected for a second malignancy...
August 31, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27157440/long-term-complication-in-follicular-lymphoma-assessing-the-risk-of-secondary-neoplasm-in-242-patients-treated-or-not-with-90-yttrium-ibritumomab-tiuxetan
#3
Marcio Miguel Andrade-Campos, Paola Liévano, Natalia Espinosa-Lara, Gloria Soro-Alcubierre, José María Grasa-Ulrich, Luis López-Gómez, Teresa Baringo, Pilar Giraldo
BACKGROUND: Non-Hodgkin lymphoma patients have a 25% increased risk of secondary primary neoplasms (SPNs). Regarding the controversy about the increased risk of SPN in patients exposed to radioimmunotherapy (RIT), we have analyzed this issue in a cohort of follicular lymphoma (FL) patients treated with/without RIT. PATIENTS AND METHODS: A retrospective study including all consecutive FL patients diagnosed since 2001 was performed. Demographic, clinical data including the incidence of any kind of neoplasm (excluding basocellular skin carcinoma) were recorded...
December 2016: European Journal of Haematology
https://www.readbyqxmd.com/read/25814758/gorlin-goltz-syndrome-a-rare-case
#4
Satyaki Ganguly, Kranti C Jaykar, Rajesh Kumar, Abhijeet Kumar Jha, P K Banerjee
Gorlin-Goltz syndrome or nevoid basal cell carcinoma syndrome is characterized by multiple basocellular epitheliomas, keratocysts in the jaws, bifid ribs, palmar and/or plantar pits and ectopic calcifications of the falx cerebri. We describe a case of Gorlin-Goltz syndrome illustrating the importance of a thorough examination including the examination of palms and soles and detailed investigations in a patient having lesions suggestive of basal cell carcinoma and multiple naevi.
March 2015: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/25713498/xeroderma-pigmentosum-and-its-dental-implications
#5
Hessa Al Wayli
Xeroderma pigmentosum (XP) is a rare autosomal recessive genetic disorder characterized by defective DNA repair leading to clinical and cellular hypersensitivity to ultraviolet (UV) radiation and carcinogenic agents. Important clinical features are: Intense cutaneous photosensitivity, xerosis, poikiloderma, actinic keratosis, acute burning under minimal sun exposure, erythemas, hyperpigmented lentiginous macules, and malignant lesions in sun-exposed areas, including basocellular carcinoma, squamous cell carcinoma, and melanoma...
January 2015: European Journal of Dentistry
https://www.readbyqxmd.com/read/25206202/gorlin-and-goltz-syndrome-a-case-report-with-surgical-review
#6
Rakesh Namdeoraoji Bahadure, Eesha Surendraji Jain, Gautam P Badole
Gorlin and Goltz syndrome are a very complex syndrome and a multisystemic process that is characterized by the presence of multiple pigmented basocellular carcinomas, keratocysts in the jaws, palmar and/or plantar pits and calcification of the falx cerebri. Along with these major features a great number minor features have also been described which involves numerous skeletical, dermatology related, neurological, ophthalmological and reproductive anomalies. It exhibits high penetrance and variable expressivity...
May 2013: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/24629737/-treatment-of-lip-cancer-material-from-the-department-of-otolaryngology-and-laryngological-oncology-medical-college-of-bydgoszcz-nicolaus-copernicus-university-torun
#7
Henryk Kaźmierczak, Zuzanna Pujanek, Wojciech Kaźmierczak, Jerzy Kochan
The subject of this study is methods and results of treatment of 21 cases of lip cancer between 2007 and 2012, which included 15 men and 6 women, aged 48-63. In 18 cases it was squamous cell carcinoma, in other 3 basocellulare carcinoma. Of the hospitalized patients the following clinical stages were found: T1 - five, T2 - five, T3 - seven, T4 - four. We operated with several techniques, we performed: V-incision and surgery according to the Webster - one patient, Rutkowski - four, Estlander - four, Karpandzic - three; in the treatment of cancer of upper lip the frontal flap was used...
March 2014: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/24596523/merkel-cell-carcinoma-description-of-five-cases
#8
Mariusz Brąclik, Robert Kwiatkowski, Dorota Katarzyna Nenko
Merkel cell carcinoma (MCC) is a rare but very aggressive skin cancer that derives from neuroendocrine cells of the skin. Merkel cell carcinoma morbidity has been continuously increasing for the last few years. Increasing reported incidence of MCC is probably connected with increasing occurrence of this kind of malignancy or with development of histological and immunohistochemical methods of sample examinations which have allowed for more precise diagnosis of skin tumor that might have previously not been accurately recognized...
2013: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/24558564/xeroderma-pigmentosum-a-case-report-with-oral-implications
#9
Camila Lopes-Cardoso, Luciana M Paes da Silva Ramos Fernandes, Julierme Ferreira-Rocha, Cleverson Teixeira-Soares, Jaison Antônio-Barreto, José Humberto-Damante
Xeroderma Pigmentosum is a rare autosomal recessive genetic disorder characterized by defective DNA repair leading to clinical and cellular hypersensitivity to ultraviolet radiation and carcinogenic agents. Important clinical features are: intense cutaneous photosensitivity, xerosis, poikiloderma, actinic keratosis, acute burning under minimal sun exposure, erythemas, hyperpigmented lentiginous macules, and malignant lesions in sun-exposed areas, including basocellular carcinoma, squamous cell carcinoma, and melanoma...
October 2012: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/24467682/the-interpolation-nasolabial-flap-the-advantageous-solution-for-nasal-tip-reconstruction-in-elderly-and-polymorbid-patients
#10
J Bayer, M Duskova, P Horyna, M Haas, K Schwarzmannová
BACKGROUND: Nasal tip is one of the most frequent areas affected by basocellular carcinoma. The treatment must avoid any postsurgical deformity, as the nasal tip is the main part of the facial triangle. Most of these patients are elderly and polymorbid. The surgeon must find a compromise between the cosmetic effect and an acceptable stress for the patient. METHODS: There were five methods of nasal tip reconstruction used on a group of fifty elderly patients with various medical comorbidities: skin graft, bilobed flap, dorsal nasal flap, forehead flap and interpolation nasolabial flap...
2013: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/24238110/-the-treatment-of-malignant-neoplasms-of-the-external-ear-canal-and-temporal-bone-in-the-department-of-otolaryngology-and-oncological-laryngology-in-bydgoszcz
#11
Henryk Kaźmierczak, Katarzyna Bilicka, Wojciech Kaźmierczak, Katarzyna Pawlak-Osińska, Joanna Janiak-Kiszka, Magdalena Dutsch-Wicherek
INTRODUCTION, MATERIAL AND METHODS, AIM OF THE STUDY: Evaluation of the methods and results of treatment of 19 cases of malignant tumors of the external auditory meatus and/or temporal bone was performed. RESULTS: In 10 cases planoepithelial carcinoma was diagnosed; in 7 cases basocellulare carcinoma; in 1 case rhabdomyosarcoma; and in 1 case malignant peripheral nerve sheath tumor were histopathologically established. In stage T1 were 8 cases, in T2 - 7, in T3 - 1 and in T4 3 patients were stated based upon clinical and radiological (HRCT and MRI) examination...
November 2013: Otolaryngologia Polska. the Polish Otolaryngology
https://www.readbyqxmd.com/read/24235333/residents-corner-july-2013-dermpath-clinic-basocellular-carcinomas-with-metastatic-potential
#12
Helena Clayton, Maxime Vernez
No abstract text is available yet for this article.
September 2013: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/24187748/-skin-cancers-infiltrating-the-skull-base
#13
REVIEW
P Pasche, M Broome, R T Daniel
Squamous cell and basocellular carcinoma of the face have an excellent prognosis. Nevertherless, a small proportion therefore of these cancers differs by a much more aggressive behavior, caracterised by a tendency to infiltrate the deep facial soft tissues and facial bones. The invasion of the craniofacial skeleton and the intracranial structures follows the embryonic fusion lines or the facial sensitive or motor nerves, sometimes years after the initial treatment. The development of craniofacial surgery, reconstruction techniques and conformational radiotherapy allows us now to offer curative guided treatments, for these advanced staged tumors with a remaining limited prognosis...
October 2, 2013: Revue Médicale Suisse
https://www.readbyqxmd.com/read/24094946/primary-cutaneous-neuroendocrine-carcinoma-merkel-cell-carcinoma-case-series-1991-2012
#14
Ramón Campillo, Elisa Gil-Carcedo, David Alonso, Luis A Vallejo, Juan M Oñate, Luis M Gil-Carcedo
INTRODUCTION AND OBJECTIVES: Merkel cell carcinoma was first described by Toker in 1972. It is an uncommon, primary neuroendocrine skin carcinoma which appears in the dermoepidermic area, grows fast, is very aggressive and has a poor prognosis. The aim of this work is to highlight the importance of this tumour, which develops mainly in the skin of the head and neck area, and whose prevalence has increased in recent years. MATERIAL AND METHOD: We gathered data on 16 patients suffering cutaneous neuroendocrine carcinoma treated at our hospital between September 12, 1991 and July 13, 2012...
November 2013: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/23524691/surgical-treatment-of-auricular-malignancies-when-the-anterior-or-posterior-skin-is-intact
#15
Mehmet Oguz Yenidunya
The layers of the auricle from front to back were addressed, respectively, as follows: anterior skin, anterior perichondrium, cartilage, posterior perichondrium, and posterior skin. Thus, if a tumor on the auricle was holding 4 of these 5 layers and not holding the anterior or posterior skin, whether it was marginally located or stabilized in the mid parts, without having to apply complete resection, the intact parts were preserved, and the defect area was repaired with full-thickness skin graft. I practiced this method on a total of 17 patients, and histopathologic analysis showed that 13 of the patients had squamous cell carcinoma, 2 had Bowen disease, 1 had basocellular carcinoma, and 1 had granulomatous chondritis...
March 2013: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/23522708/-what-s-new-in-oncology
#16
S Dalle
In cutaneous oncology, the year 2012 was marked by the consolidation of earlier results as well as the emergence of new therapeutic perspectives. The consolidated results most notably concern the use of MAP-kinase inhibitors (anti-MEK, anti-BRAF) in the treatment of patients with metastatic melanoma. Vismodegib (an SMO inhibitor), used in the treatment of multiple basocellular carcinomas that are inoperable or that have developed in patients suffering from Gorlin syndrome, has been the subject of publication of large-scale studies...
December 2012: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/23239863/surgical-solutions-for-the-reconstruction-of-the-lower-eyelid-canthotomy-and-lateral-cantholisis-for-full-thickness-reconstruction-of-the-lower-eyelid
#17
Gian Marco Tomassini, Angela Luisa Ricci, Piero Covarelli, Francesca Cencetti, Vincenzo Ansidei, Antonio Rulli, Stefano Simonetti
The lower eyelid is the most common site of tumors of the orbital region, usually of basocellular skin carcinoma, whose incidence is increasing with population aging in Western countries. The treatment must achieve the complete removal of the neoplasm in order to prevent recurrences, thus requiring eyelid and periocular reconstruction. Several techniques are described for eyelid defect reconstruction, aiming for direct suture eased by flaps, or considering the use of grafts. We report our experience with 22 patients operated on for basocellular carcinoma of the lower eyelid, for wich defects were repaired by means of a full-thickness reconstruction using a canthotomy and lateral cantholisis; in 13 patients the canthotomy was combined with a lateral-canthal flap...
January 2013: In Vivo
https://www.readbyqxmd.com/read/23087465/anaesthetic-management-in-gorlin-goltz-syndrome
#18
Kundan S Gosavi, Surbhi D Mundada
Gorlin-Goltz syndrome is a rare autosomal-dominant syndrome related to mutation in "Patched" tumour suppressor gene on chromosome 9. Basocellular carcinomas, odontogenic keratocysts, palmar and/or plantar pits and ectopic calcifications of the falx cerebri are its major features, along with more than 100 minor features. Odontogenic cysts, notorious for recurrence, can make endotracheal intubation difficult, requiring modification of the standard intubation technique. We report such a case managed successfully by awake fibreoptic intubation...
July 2012: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/22822616/the-results-of-treatment-of-basoceltular-carcinomas-of-the-head-skin
#19
Darko Lukic, Reuf Karabeg, Pavle Jeremic, Jadran Bandic, Malik Jakirlic, Nenad Babic, Amela Karabeg, Sanja Sibincic, Predrag Lazic
INTRODUCTION: Basocellular skin carcinoma (BCC) is the most common cancer in the human population. BCC almost appeared at adult's people, but it can be found at children, too. THE AIM: The aim of this study was to determine which the position of BCC on the head skin is the most difficult for the treatment and what the reasons are for it. METHODS: With the prospective study, from June 2004 to June 2011, were compared the results of treatment of basocellular carcinomas (BCC) of the head skin...
2012: Medical Archives
https://www.readbyqxmd.com/read/22549747/electrochemotherapy-for-non-melanoma-head-and-neck-cancers-clinical-outcomes-in-25-patients
#20
Maurizio Gargiulo, Angelo Papa, Pasquale Capasso, Mariagrazia Moio, Ermenegildo Cubicciotti, Salvatore Parascandolo
OBJECTIVE: To evaluate and confirm the efficacy and safety of electrochemotherapy (ECT) using bleomicyn in a large series of non-melanoma head and neck cancers. BACKGROUND: ECT combines chemotherapy and electroporation to increase drug uptake into cancer cells. ECT has proven to be effective in the treatment of tumor nodules of cutaneous and subcutaneous localization. Up to now, this therapy has been mainly used as a local control of melanoma skin metastasis. Few studies have focused on its role in the treatment of head and neck cutaneous and subcutaneous cancers...
June 2012: Annals of Surgery
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