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Roy Adaptation Model

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https://www.readbyqxmd.com/read/29152579/streptococcus-pneumoniae-tigr4-phase-locked-opacity-variants-differ-in-virulence-phenotypes
#1
Melissa B Oliver, Ankita Basu Roy, Ranjit Kumar, Elliot J Lefkowitz, W Edward Swords
Streptococcus pneumoniae (pneumococcus) is a leading human pathogen that can cause serious localized and invasive diseases. Pneumococci can undergo a spontaneous and reversible phase variation that is reflected in colony opacity and which allows the population to adapt to different host environments. Generally, transparent variants are adapted for nasopharyngeal colonization, whereas opaque variants are associated with invasive disease. In recent work, colony phase variation was shown to occur by means of recombination events to generate multiple alleles of the hsdS targeting domain of a DNA methylase complex, which mediates epigenetic changes in gene expression...
November 2017: MSphere
https://www.readbyqxmd.com/read/29113112/g2-m-phase-checkpoint-adaptation-and-micronuclei-formation-as-mechanisms-that-contribute-to-genomic-instability-in-human-cells
#2
REVIEW
Danî Kalsbeek, Roy M Golsteyn
One of the most common characteristics of cancer cells is genomic instability. Recent research has revealed that G2/M-phase checkpoint adaptation-entering mitosis with damaged DNA-contributes to genomic changes in experimental models. When cancer cells are treated with pharmacological concentrations of genotoxic agents, they undergo checkpoint adaptation; however, a small number of cells are able to survive and accumulate micronuclei. These micronuclei harbour damaged DNA, and are able to replicate and reincorporate their DNA into the main nucleus...
November 6, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29047773/transient-dynamic-distributed-strain-sensing-using-photonic-crystal-waveguides
#3
Hosangadi Prutvi Sagar, Vignesh Mahalingam, Debiprosad Roy Mahapatra, Gopalkrishna Hegde, Sathyanarayana Hanagud, Mohammad Rizwanur Rahman
This paper presents a new type of one-dimensional photonic crystal (PC) waveguide sensor and a technique for prediction of transient strain response accurately. The PC waveguide is integrated on a silicon substrate. We investigate the effect of non-uniform strain localization on the optical signal and use that information to capture the transient strain. Wavelength shift due to distributed strain field is modeled by incorporating the mechanically deformed geometry and photo-acoustic coupling through Pockels effect in a finite element formulation...
October 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29036208/transitioning-couple-s-voluntary-hiv-counseling-and-testing-cvct-from-stand-alone-weekend-services-into-routine-antenatal-and-vct-services-in-government-clinics-in-zambia-s-two-largest-cities
#4
Mubiana Inambao, William Kilembe, Lauren A Canary, Nancy L Czaicki, Matilda Kakungu-Simpungwe, Roy Chavuma, Kristin M Wall, Amanda Tichacek, Julie Pulerwitz, Ibou Thior, Elwyn Chomba, Susan A Allen
INTRODUCTION: Most HIV infections in Africa are acquired by married/cohabiting adults and WHO recommends couple's voluntary HIV counseling and testing (CVCT) for prevention. The handover from NGO-sponsored weekend CVCT to government-sponsored services in routine weekday antenatal care (ANC) and individual voluntary testing and counseling (VCT) services in Zambia's two largest cities from 2009-2015 is described. METHODS: Government clinic counselors were trained to provide CVCT, and along with community health workers they promoted CVCT services in their clinic and surrounding areas...
2017: PloS One
https://www.readbyqxmd.com/read/28969831/development-of-a-model-forecasting-dermanyssus-gallinae-s-population-dynamics-for-advancing-integrated-pest-management-in-laying-hen-facilities
#5
Monique F Mul, Johan W van Riel, Lise Roy, Johan Zoons, Geert André, David R George, Bastiaan G Meerburg, Marcel Dicke, Simon van Mourik, Peter W G Groot Koerkamp
The poultry red mite, Dermanyssus gallinae, is the most significant pest of egg laying hens in many parts of the world. Control of D. gallinae could be greatly improved with advanced Integrated Pest Management (IPM) for D. gallinae in laying hen facilities. The development of a model forecasting the pests' population dynamics in laying hen facilities without and post-treatment will contribute to this advanced IPM and could consequently improve implementation of IPM by farmers. The current work describes the development and demonstration of a model which can follow and forecast the population dynamics of D...
October 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28956415/patients%C3%A2-adaptation-strategies-for-colostomates-with-a-self-image-disturbance-after-a-month-of-surgery
#6
Foued Trabelsi, Saber Ben Abeljalil, Fethi Derbal, Iheb Bougmiza
BACKGROUND: the establishment of a colostomy is a difficult time for the patient since it undergoes physical, psychological and social changes resulting in the modification of the body self-image. Purpose and Framework : this study aims to identify adaptation strategies for colostomates who have a disturbance of self-image after a month of surgery depending on the Roy Adaptation Model. METHODS: a descriptive quantitative study was realized with a sample of 70 patients with colostomy in the department of surgery Farhat Hached and Sahloul Hospital in Sousse...
August 17, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28944641/-unknown-title
#7
(no author information available yet)
Background : the establishment of a colostomy is a difficult time for the patient since it undergoes physical, psychological and social changes resulting in the modification of the body self-image. Purpose and Framework : this study aims to identify adaptation strategies for colostomates who have a disturbance of self-image after a month of surgery depending on the Roy Adaptation Model. Methods : a descriptive quantitative study was realized with a sample of 70 patients with colostomy in the department of surgery Farhat Hached and Sahloul Hospital in Sousse...
August 17, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28934037/middle-range-theory-coping-and-adaptation-with-active-aging
#8
Martha Elba Salazar-Barajas, Bertha Cecilia Salazar-González, Esther Carlota Gallegos-Cabriales
Various disciplines focus on a multiplicity of aspects of aging: lifestyles, personal biological factors, psychological conditions, health conditions, physical environment, and social and economic factors. The aforementioned are all related to the determinants of active aging. The aim is to describe the development of a middle-range theory based on coping and adaptation with active aging. Concepts and relationships derived from Roy's model of adaptation are included. The proposed concepts are hope, health habits, coping with aging, social relations, and active aging...
October 2017: Nursing Science Quarterly
https://www.readbyqxmd.com/read/28899245/evaluation-of-healthy-living-wellness-program-with-minority-underserved-economically-disadvantaged-older-adults
#9
Peggy C Tallier, Patricia R Reineke, Keville Frederickson
The purpose of this Roy adaptation model-guided study was to test the effectiveness of a student registered nurse intern-led nursing intervention entitled the Healthy Living Wellness Program. A one-group pretest/posttest preexperimental design was used. The intervention was imparted to minority, underserved, economically disadvantaged older adults ( N = 30). Significant findings pre- and postintervention were reported for body mass index, waist circumference, self-reported blood glucose, and weight. The findings supported the effectiveness of the nursing intervention, the Healthy Living Wellness Program, guided by the Roy adaptation model...
April 2017: Nursing Science Quarterly
https://www.readbyqxmd.com/read/28852426/cross-cultural-adaptation-and-validation-of-spanish-version-of-the-foot-and-ankle-ability-measures-faam-sp
#10
Pablo Cervera-Garvi, Ana Belen Ortega-Avila, Jose Miguel Morales-Asencio, Jose Antonio Cervera-Marin, Rob Roy Martin, Gabriel Gijon-Nogueron
BACKGROUND: The Foot and Ankle Ability Measure (FAAM) is a Patient Reported Outcome (PRO) commonly used to determine the effectiveness of therapeutic interventions for patients with foot and ankle pathologies and associated impairments of body function and structure, activity limitations, and participation restrictions. The aim of this study was to cross-culturally adapt the FAAM into Spanish. METHODS: Cross-cultural adaptation was performed according to the international guidelines of the International Society for Pharmacoeconomics and Outcomes Research...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/28825933/the-roy-adaptation-model-a-theoretical-framework-for-nurses-providing-care-to-individuals-with-anorexia-nervosa
#11
Karen M Jennings
Using a nursing theoretical framework to understand, elucidate, and propose nursing research is fundamental to knowledge development. This article presents the Roy Adaptation Model as a theoretical framework to better understand individuals with anorexia nervosa during acute treatment, and the role of nursing assessments and interventions in the promotion of weight restoration. Nursing assessments and interventions situated within the Roy Adaptation Model take into consideration how weight restoration does not occur in isolation but rather reflects an adaptive process within external and internal environments, and has the potential for more holistic care...
October 2017: ANS. Advances in Nursing Science
https://www.readbyqxmd.com/read/28753669/multiscale-adaptive-analysis-of-circadian-rhythms-and-intradaily-variability-application-to-actigraphy-time-series-in-acute-insomnia-subjects
#12
Ruben Fossion, Ana Leonor Rivera, Juan C Toledo-Roy, Jason Ellis, Maia Angelova
Circadian rhythms become less dominant and less regular with chronic-degenerative disease, such that to accurately assess these pathological conditions it is important to quantify not only periodic characteristics but also more irregular aspects of the corresponding time series. Novel data-adaptive techniques, such as singular spectrum analysis (SSA), allow for the decomposition of experimental time series, in a model-free way, into a trend, quasiperiodic components and noise fluctuations. We compared SSA with the traditional techniques of cosinor analysis and intradaily variability using 1-week continuous actigraphy data in young adults with acute insomnia and healthy age-matched controls...
2017: PloS One
https://www.readbyqxmd.com/read/28725201/nature-and-specificity-of-gestural-disorder-in-children-with-developmental-coordination-disorder-a-multiple-case-study
#13
Orianne Costini, Arnaud Roy, Chrystelle Remigereau, Sylvane Faure, Catherine Fossoud, Didier Le Gall
Aim: Praxis assessment in children with developmental coordination disorder (DCD) is usually based on tests of adult apraxia, by comparing across types of gestures and input modalities. However, the cognitive models of adult praxis processing are rarely used in a comprehensive and critical interpretation. These models generally involve two systems: a conceptual system and a production system. Heterogeneity of deficits is consistently reported in DCD, involving other cognitive skills such as executive or visual-perceptual and visuospatial functions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28715353/learned-expectations-and-uncertainty-facilitate-pain-during-classical-conditioning
#14
Veronique A Taylor, Luke Chang, Pierre Rainville, Mathieu Roy
Pain spontaneously activates adaptive and dynamic learning processes affecting the anticipation of, and the responses to, future pain. Computational models of associative learning effectively capture the production and ongoing changes in conditioned anticipatory responses (eg, skin conductance response), but the impact of this dynamic process on unconditional pain responses remains poorly understood. Here, we investigated the dynamic modulation of pain and the nociceptive flexion reflex by fear learning in healthy human adult participants undergoing a classical conditioning procedure involving an acquisition, reversal and extinction phase...
August 2017: Pain
https://www.readbyqxmd.com/read/28714452/predict-moral-distress-using-workplace-stress-stress-of-conscience-mediated-by-coping-using-roy-adaptation-model-a-path-analysis
#15
Muder Alkrisat
BACKGROUND: Moral distress can be predisposed when nurses are exposed to ambiguous moral situations. PURPOSE: Is to test a conceptual model based on Roy adaptation model (RAM) to examine the relationship among workplace stress, conscience stress, and moral distress mediated by coping. DESIGN: A correlational, cross sectional. RESULTS: Data were collected from 199 licensed nurses. The findings indicated that workplace stress was related negatively to coping processes (β = -...
December 1, 2016: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28692797/versatile-large-area-custom-feature-van-der-waals-epitaxy-of-topological-insulators
#16
Tanuj Trivedi, Anupam Roy, Hema C P Movva, Emily S Walker, Seth R Bank, Dean P Neikirk, Sanjay K Banerjee
As the focus of applied research in topological insulators (TI) evolves, the need to synthesize large-area TI films for practical device applications takes center stage. However, constructing scalable and adaptable processes for high-quality TI compounds remains a challenge. To this end, a versatile van der Waals epitaxy (vdWE) process for custom-feature bismuth telluro-sulfide TI growth and fabrication is presented, achieved through selective-area fluorination and modification of surface free-energy on mica...
July 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28651368/risk-of-recurrence-in-pituitary-neuroendocrine-tumors-a-prospective-study-using-a-five-tiered-classification
#17
Gérald Raverot, Emmanuelle Dantony, Julie Beauvy, Alexandre Vasiljevic, Sara Mikolasek, Françoise Borson-Chazot, Emmanuel Jouanneau, Pascal Roy, Jacqueline Trouillas
Background: Most pituitary neuroendocrine tumors (PitNETs) show benign behavior, but a substantial number are invasive, recur, or resist medical treatment. Based on a retrospective case-control study, we recently proposed a classification of PitNETs of prognostic relevance. This prospective study aims to test the value of this classification in an independent patient cohort. Methods: All patients who underwent PitNET surgery from 2007 to 2012 in one single center were included...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28606767/model-identifies-causes-of-nasal-drying-during-pressurised-breathing
#18
David E White, Roy J Nates, Jim Bartley
Patients nasally breathing pressurised air frequently experience symptoms suggestive of upper airway drying. While supplementary humidification is often used for symptom relief, the cause(s) of nasal drying symptoms remains speculative. Recent investigations have found augmented air pressure affects airway surface liquid (ASL) supply and inter-nasal airflow apportionment. However the influence these two factors have on ASL hydration is unknown. The purpose of this study is to determine how ASL supply and airflow apportionment affect ASL hydration status for both ambient and pressurised air breathing conditions...
September 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28566683/combinatorial-delivery-of-dual-and-triple-tlr-agonists-via-polymeric-pathogen-like-particles-synergistically-enhances-innate-and-adaptive-immune-responses
#19
Ranjna Madan-Lala, Pallab Pradhan, Krishnendu Roy
Despite decades of research very few vaccine-adjuvants have received FDA approval. Two fundamental challenges plague clinical translation of vaccine-adjuvants: reducing acute toxicities that result from systemic diffusion of many soluble adjuvants, and delivering multiple adjuvants at the same time to mimic the synergistic immune-stimulation of pathogens, while being safe. In order to address these barriers, we evaluated combinations of four clinically relevant immune-agonists, specifically Toll-like receptor (TLR) ligands, using biodegradable, polymer microparticles...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28559461/the-hgf-c-met-pathway-is-a-driver-and-biomarker-of-vegfr-inhibitor-resistance-and-vascular-remodeling-in-non-small-cell-lung-cancer
#20
Tina Cascone, Li Xu, Heather Y Lin, Wenbin Liu, Hai T Tran, Yuan Liu, Kathryn Howells, Vincent Haddad, Emer Hanrahan, Monique B Nilsson, Maria A Cortez, Uma Giri, Humam Kadara, Babita Saigal, Yun-Yong Park, Weiyi Peng, Ju-Seog Lee, Anderson J Ryan, Juliane M Jüergensmeier, Roy S Herbst, Jing Wang, Robert R Langley, Ignacio I Wistuba, Jack J Lee, John V Heymach
Purpose: Resistance to VEGFR inhibitors is a major obstacle in the treatment of non-small cell lung cancer (NSCLC). We investigated the cellular mechanisms mediating resistance of NSCLCs to VEGFR tyrosine kinase inhibitors.Experimental Design: We generated murine models of human NSCLC and performed targeted inhibition studies with the VEGFR TKIs cediranib and vandetanib. We used species-specific hybridization of microarrays to compare cancer (human) and stromal (mouse) cell transcriptomes of TKI-sensitive and -resistant tumors...
September 15, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
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