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Roy Adaptation Model

Laura B Ferguson, R Adron Harris, Roy Dayne Mayfield
The alcohol research field has amassed an impressive number of gene expression datasets spanning key brain areas for addiction, species (humans as well as multiple animal models), and stages in the addiction cycle (binge/intoxication, withdrawal/negative effect, and preoccupation/anticipation). These data have improved our understanding of the molecular adaptations that eventually lead to dysregulation of brain function and the chronic, relapsing disorder of addiction. Identification of new medications to treat alcohol use disorder (AUD) will likely benefit from the integration of genetic, genomic, and behavioral information included in these important datasets...
March 1, 2018: Psychopharmacology
Henriett Butz, Qiang Ding, Roy Nofech-Mozes, Zsuzsanna Lichner, Heyu Ni, George M Yousef
Upon sunitinib treatment of metastatic renal cell carcinoma patients eventually acquire resistance. Our aim was to investigate microRNAs behind sunitinib resistance. We developed an in vivo xenograft and an in vitro model and compared morphological, immunhistochemical, transcriptomical and miRNome data changes during sunitinib response and resistance by performing next-generation mRNA and miRNA sequencing. Complex bioinformatics (pathway, BioFunction and network) analysis were performed. Results were validated by in vitro functional assays...
January 12, 2018: Oncotarget
Anirban Mitra, Sudipta Roy, Somais Roy, Sanjit Kumar Setua
BACKGROUND AND OBJECTIVES: Retinal fundus images are extensively used in manually or without human intervention to identify and analyze various diseases. Due to the comprehensive imaging arrangement, there is a large radiance, reflectance and contrast inconsistency within and across images. METHOD: A novel method is proposed based on the cataract physical model to reduce the generated blurriness of the fundus image at the time of image acquisition through the thin layer of cataract by the fundus camera...
March 2018: Computer Methods and Programs in Biomedicine
D Agathangelou, Y Orozco-Gonzalez, M Del Carmen Marín, P P Roy, J Brazard, H Kandori, K-H Jung, J Léonard, T Buckup, N Ferré, M Olivucci, S Haacke
Anabaena sensory rhodopsin (ASR) is a particular microbial retinal protein for which light-adaptation leads to the ability to bind both the all-trans, 15-anti (AT) and the 13-cis, 15-syn (13C) isomers of the protonated Schiff base of retinal (PSBR). In the context of obtaining insight into the mechanisms by which retinal proteins catalyse the PSBR photo-isomerization reaction, ASR is a model system allowing to study, within the same protein, the protein-PSBR interactions for two different PSBR conformers at the same time...
February 1, 2018: Faraday Discussions
Rajendra Mohan Panda, Mukunda Dev Behera, Partha Sarathi Roy
Understanding the impact of climate change on species invasion is crucial for sustainable biodiversity conservation. Through this study, we try to answer how species differing in phenological cycles, specifically Cassia tora and Lantana camara, differ in the manner in which they invade new regions in India in the future climate. Since both species occupy identical niches, exploring their invasive potential in different climate change scenarios will offer critical insights into invasion and inform ecosystem management...
December 28, 2017: Journal of Environmental Management
Ligia Patricia Arroyo-Marlés, Maryory Guevara-Lozano, Beatriz Pérez-Giraldo, Beatriz Sánchez-Herrera
OBJECTIVE: To develop a nursing practice model for the Clinic of the University of the La Sabana that supports the adaptive process of patients during and after their hospital experience. METHODOLOGY: This is a descriptive, methodological study implemented in different phases: (1) characterization of the context, (2) identification of the need for a nursing practice model for strengthening care, (3) literature review, (4) description of the model, and (5) validation...
December 26, 2017: Journal of Nursing Management
Aindrila Biswas, Mousumi Roy
Economic growth in the past decades has resulted in change in consumption pattern and emergence of tech-savvy generation with unprecedented increase in the usage of social network technology. In this paper, the technology acceptance value gap adapted from the technology acceptance model has been applied as a tool supporting social network technology usage and subsequent promotion of sustainable consumption. The data generated through the use of structured questionnaires have been analyzed using structural equation modeling...
December 15, 2017: Environmental Science and Pollution Research International
Nina M Flanagan
Persistent pain in older adults is difficult to assess and therefore address consistently. The experience of pain is individual, and therefore a comprehensive way to assess pain is required. Roy's adaptation model offers a systematic way of evaluating pain in the older adult. In this column, the author shares some statistics about persistent pain and a case study using Roy's model as a system for assessment.
January 2018: Nursing Science Quarterly
Melissa B Oliver, Ankita Basu Roy, Ranjit Kumar, Elliot J Lefkowitz, W Edward Swords
Streptococcus pneumoniae (pneumococcus) is a leading human pathogen that can cause serious localized and invasive diseases. Pneumococci can undergo a spontaneous and reversible phase variation that is reflected in colony opacity and which allows the population to adapt to different host environments. Generally, transparent variants are adapted for nasopharyngeal colonization, whereas opaque variants are associated with invasive disease. In recent work, colony phase variation was shown to occur by means of recombination events to generate multiple alleles of the hsdS targeting domain of a DNA methylase complex, which mediates epigenetic changes in gene expression...
November 2017: MSphere
Danî Kalsbeek, Roy M Golsteyn
One of the most common characteristics of cancer cells is genomic instability. Recent research has revealed that G2/M-phase checkpoint adaptation-entering mitosis with damaged DNA-contributes to genomic changes in experimental models. When cancer cells are treated with pharmacological concentrations of genotoxic agents, they undergo checkpoint adaptation; however, a small number of cells are able to survive and accumulate micronuclei. These micronuclei harbour damaged DNA, and are able to replicate and reincorporate their DNA into the main nucleus...
November 6, 2017: International Journal of Molecular Sciences
Hosangadi Prutvi Sagar, Vignesh Mahalingam, Debiprosad Roy Mahapatra, Gopalkrishna Hegde, Sathyanarayana Hanagud, Mohammad Rizwanur Rahman
This paper presents a new type of one-dimensional photonic crystal (PC) waveguide sensor and a technique for prediction of transient strain response accurately. The PC waveguide is integrated on a silicon substrate. We investigate the effect of non-uniform strain localization on the optical signal and use that information to capture the transient strain. Wavelength shift due to distributed strain field is modeled by incorporating the mechanically deformed geometry and photo-acoustic coupling through Pockels effect in a finite element formulation...
October 1, 2017: Applied Optics
Mubiana Inambao, William Kilembe, Lauren A Canary, Nancy L Czaicki, Matilda Kakungu-Simpungwe, Roy Chavuma, Kristin M Wall, Amanda Tichacek, Julie Pulerwitz, Ibou Thior, Elwyn Chomba, Susan A Allen
INTRODUCTION: Most HIV infections in Africa are acquired by married/cohabiting adults and WHO recommends couple's voluntary HIV counseling and testing (CVCT) for prevention. The handover from NGO-sponsored weekend CVCT to government-sponsored services in routine weekday antenatal care (ANC) and individual voluntary testing and counseling (VCT) services in Zambia's two largest cities from 2009-2015 is described. METHODS: Government clinic counselors were trained to provide CVCT, and along with community health workers they promoted CVCT services in their clinic and surrounding areas...
2017: PloS One
Monique F Mul, Johan W van Riel, Lise Roy, Johan Zoons, Geert André, David R George, Bastiaan G Meerburg, Marcel Dicke, Simon van Mourik, Peter W G Groot Koerkamp
The poultry red mite, Dermanyssus gallinae, is the most significant pest of egg laying hens in many parts of the world. Control of D. gallinae could be greatly improved with advanced Integrated Pest Management (IPM) for D. gallinae in laying hen facilities. The development of a model forecasting the pests' population dynamics in laying hen facilities without and post-treatment will contribute to this advanced IPM and could consequently improve implementation of IPM by farmers. The current work describes the development and demonstration of a model which can follow and forecast the population dynamics of D...
October 15, 2017: Veterinary Parasitology
Foued Trabelsi, Saber Ben Abeljalil, Fethi Derbal, Iheb Bougmiza
BACKGROUND: the establishment of a colostomy is a difficult time for the patient since it undergoes physical, psychological and social changes resulting in the modification of the body self-image. Purpose and Framework : this study aims to identify adaptation strategies for colostomates who have a disturbance of self-image after a month of surgery depending on the Roy Adaptation Model. METHODS: a descriptive quantitative study was realized with a sample of 70 patients with colostomy in the department of surgery Farhat Hached and Sahloul Hospital in Sousse...
August 17, 2017: Recherche en Soins Infirmiers
(no author information available yet)
Background : the establishment of a colostomy is a difficult time for the patient since it undergoes physical, psychological and social changes resulting in the modification of the body self-image. Purpose and Framework : this study aims to identify adaptation strategies for colostomates who have a disturbance of self-image after a month of surgery depending on the Roy Adaptation Model. Methods : a descriptive quantitative study was realized with a sample of 70 patients with colostomy in the department of surgery Farhat Hached and Sahloul Hospital in Sousse...
August 17, 2017: Recherche en Soins Infirmiers
Martha Elba Salazar-Barajas, Bertha Cecilia Salazar-González, Esther Carlota Gallegos-Cabriales
Various disciplines focus on a multiplicity of aspects of aging: lifestyles, personal biological factors, psychological conditions, health conditions, physical environment, and social and economic factors. The aforementioned are all related to the determinants of active aging. The aim is to describe the development of a middle-range theory based on coping and adaptation with active aging. Concepts and relationships derived from Roy's model of adaptation are included. The proposed concepts are hope, health habits, coping with aging, social relations, and active aging...
October 2017: Nursing Science Quarterly
Peggy C Tallier, Patricia R Reineke, Keville Frederickson
The purpose of this Roy adaptation model-guided study was to test the effectiveness of a student registered nurse intern-led nursing intervention entitled the Healthy Living Wellness Program. A one-group pretest/posttest preexperimental design was used. The intervention was imparted to minority, underserved, economically disadvantaged older adults ( N = 30). Significant findings pre- and postintervention were reported for body mass index, waist circumference, self-reported blood glucose, and weight. The findings supported the effectiveness of the nursing intervention, the Healthy Living Wellness Program, guided by the Roy adaptation model...
April 2017: Nursing Science Quarterly
Pablo Cervera-Garvi, Ana Belen Ortega-Avila, Jose Miguel Morales-Asencio, Jose Antonio Cervera-Marin, Rob Roy Martin, Gabriel Gijon-Nogueron
BACKGROUND: The Foot and Ankle Ability Measure (FAAM) is a Patient Reported Outcome (PRO) commonly used to determine the effectiveness of therapeutic interventions for patients with foot and ankle pathologies and associated impairments of body function and structure, activity limitations, and participation restrictions. The aim of this study was to cross-culturally adapt the FAAM into Spanish. METHODS: Cross-cultural adaptation was performed according to the international guidelines of the International Society for Pharmacoeconomics and Outcomes Research...
2017: Journal of Foot and Ankle Research
Karen M Jennings
Using a nursing theoretical framework to understand, elucidate, and propose nursing research is fundamental to knowledge development. This article presents the Roy Adaptation Model as a theoretical framework to better understand individuals with anorexia nervosa during acute treatment, and the role of nursing assessments and interventions in the promotion of weight restoration. Nursing assessments and interventions situated within the Roy Adaptation Model take into consideration how weight restoration does not occur in isolation but rather reflects an adaptive process within external and internal environments, and has the potential for more holistic care...
October 2017: ANS. Advances in Nursing Science
Ruben Fossion, Ana Leonor Rivera, Juan C Toledo-Roy, Jason Ellis, Maia Angelova
Circadian rhythms become less dominant and less regular with chronic-degenerative disease, such that to accurately assess these pathological conditions it is important to quantify not only periodic characteristics but also more irregular aspects of the corresponding time series. Novel data-adaptive techniques, such as singular spectrum analysis (SSA), allow for the decomposition of experimental time series, in a model-free way, into a trend, quasiperiodic components and noise fluctuations. We compared SSA with the traditional techniques of cosinor analysis and intradaily variability using 1-week continuous actigraphy data in young adults with acute insomnia and healthy age-matched controls...
2017: PloS One
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