Simone Rossi, Alessandra Cinti, Francesca Viberti, Alberto Benelli, Francesco Neri, David De Monte, Alessandro Giannotta, Sara Romanella, Carmelo Smeralda, Aniello Donniacuo, Domenico Prattichizzo, Patrizio Pasqualetti, Emiliano Santarnecchi, Marco Mandalà
OBJECTIVE: The vestibular cortex is a multisensory associative region that, in neuroimaging investigations, is activated by slow-frequency (1-2 Hz) galvanic stimulation of peripheral receptors. We aimed to directly activate the vestibular cortex with biophysically modeled transcranial oscillatory current stimulation (tACS) in the same frequency range. METHODS: Thirty healthy subjects and one rare patient with chronic bilateral vestibular deafferentation underwent, in a randomized, double-blind, controlled trial, to tACS at slow (1 or 2 Hz) or higher (10 Hz) frequency and sham stimulations, over the Parieto-Insular Vestibular Cortex (PIVC), while standing on a stabilometric platform...
July 5, 2023: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology