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https://www.readbyqxmd.com/read/29780576/merkel-cell-carcinoma-extended-lymphadenectomy-and-reconstruction-with-biosynthetic-prosthesis
#1
Enrico Coppola Bottazzi, Adele Noviello, Nicola Moles, Antonio Miro, Augusto Striano, Mario Baiamonte, Francesco Esposito, Francesco Crafa
Introduction: Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. Case report: We report a case of Merkel's abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE® BIO-A® . Discussion: Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin...
May 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29779979/intercalary-prosthetic-reconstruction-for-pathologic-diaphyseal-humeral-fractures-due-to-metastatic-tumors-outcomes-and-improvements
#2
Jie Zhao, Xiu-Chun Yu, Ming Xu, Kai Zheng, Yong-Cheng Hu, Feng Wang, Deng-Xing Lun
BACKGROUND: There is a high aseptic loosening rate for intercalary prosthetic reconstruction for malignant tumors. We evaluated outcomes and complications of intercalary prosthetic reconstruction for pathologic diaphyseal humeral fractures and report the application of an extracortical plate that can prevent early loosening. METHODS: We retrospectively analyzed 9 patients who underwent intercalary prosthetic reconstruction for pathologic diaphyseal humeral fractures secondary to metastatic diseases between March 2011 and September 2017...
May 17, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29762195/functional-outcomes-and-complications-after-oncologic-reconstruction-of-the-proximal-humerus
#3
Sjoerd Nota, Teun Teunis, Joost Kortlever, Marco Ferrone, John Ready, Mark Gebhardt, Kevin Raskin, Francis Hornicek, Joseph Schwab, Santiago Lozano Calderon
BACKGROUND: No consensus exists on the best method of articular reconstruction in patients who require proximal humerus resection for the management of primary bone sarcomas, soft-tissue sarcomas extending into the bone, benign and locally aggressive primary bone tumors, and metastatic disease. METHODS: We identified patients from two institutions who underwent wide resection of the proximal humerus along with oncologic reconstruction using osteoarticular allografts (OAs), endoprostheses, or allograft-prosthesis composites...
June 1, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29755278/orbital-tumor-associated-with-a-microphthalmic-eye-and-colobomatous-cleft-pilocytic-astrocytoma-glioma-or-massive-retinal-gliosis
#4
Rita Van Ginderdeuren, Rafael Sciot, Ilse Mombaerts
A 11-year-old boy with congenital microphthalmos of the right eye presented with gradual protrusion of his ocular prosthesis. MRI showed an orbital mass adjacent to the microphthalmic eye. After removal of the eye and the orbital soft tissue mass a gliotic mass, resembling a pilocytic astrocytoma WHO grade 1 (glioma) was diagnosed. Through a colobomatous cleft in the eye the tumour spread in the orbit. There were no clinical signs of neurofibromatosis 1. This case showed a very rare association between a microphthalmic and colobomatous eye and pilocytic astrocytoma, grade 1...
January 2018: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29723462/-prevention-and-treatment-of-erectile-dysfunction-after-prostatectomy-an-update
#5
REVIEW
Peng Xu, Yin-Huai Wang
Prostate cancer has the highest incidence among malignant tumors of the urinary system in China. Radical prostatectomy (RP) is the most effective treatment for localized prostate cancer with a good long-term prognosis. Erectile dysfunction (ED) is a common complication after RP, which seriously affects the patient's quality of life. With the rising incidence and early diagnosis of prostate cancer, the proportion of young cases of RP is increasing, and so is the importance of the treatment of post-RP ED. The restoration of erectile function after RP is closely related to the timing of penile rehabilitation as well as to pre- and intra-operative measures such as surgical strategies and methods...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29688908/surgical-outcomes-after-limb-sparing-resection-and-reconstruction-for-pelvic-sarcoma-a-systematic-review
#6
Robert J Wilson, Thomas H Freeman, Jennifer L Halpern, Herbert S Schwartz, Ginger E Holt
BACKGROUND: Limb-sparing resection and reconstruction for pelvic sarcomas in multiple small studies have been fraught with complications, reoperations, and impaired patient function. However, the non-oncologic complication and reoperation rates and functional outcomes for patients have never been rigorously compiled, to our knowledge. A systematic review was undertaken to more accurately determine the non-oncologic complication and reoperation rates and functional outcomes for patients after pelvic sarcoma resection and reconstruction...
April 2018: JBJS Reviews
https://www.readbyqxmd.com/read/29682262/unicystic-ameloblastoma-rehabilitation-with-chin-graft-harvested-and-implant-supported-fixed-prosthesis
#7
J Sanz-Alonso, N Martínez-Rodríguez, M Martín-Ares, C Barona-Dorado, J Cortés Bretón-Brinkmann, J M Martínez-González
Objective: The objective is to present a clinical case of a 38-year-old male with a maxillary unicystic ameloblastoma treated by means of tumor block resection followed by chin-harvested graft placement in order to place two dental implants for esthetic and functional rehabilitation. Methods: Ameloblastoma is a benign odontogenic tumor characterized by local aggression and a high rate of recurrence; the latter partly depends on how it is treated. Complete resection of the tumor, which usually prevents recurrence, produces bone defects of varying size that must be reconstructed later on...
October 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29656899/long-term-outcome-of-patients-with-or-without-osseointegrated-implants-after-resection-of-mandibular-ameloblastoma-and-reconstruction-with-vascularized-bone-graft-functional-assessment-and-quality-of-life
#8
Marco Pappalardo, Chung-Kan Tsao, Man Lung Tsang, Jie Zheng, Yang-Ming Chang, Chi-Ying Tsai
BACKGROUND: The optimal management after the resection of mandibular ameloblastoma has been very challenging to surgeons. The aim of this study is to evaluate the functional, aesthetic, and quality of life outcomes of patients who had a segmental mandibular resection and immediate reconstruction with or without osseointegrated implants. METHOD: Patients' demographics, tumor characteristics, treatment, and complications were retrieved. Patients were divided into two groups: dental rehabilitated vs...
March 28, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29650420/denosumab-treatment-of-inoperable-or-locally-advanced-giant-cell-tumor-of-bone-multicenter-analysis-outside-clinical-trial
#9
Piotr Rutkowski, Louie Gaston, Aneta Borkowska, Silvia Stacchiotti, Hans Gelderblom, Giacomo Giulio Baldi, Emanuela Palmerini, Paolo Casali, Alessandro Gronchi, Michael Parry, Domenico Andrea Campanacci, Guido Scoccianti, Michal Wagrodzki, Stefano Ferrari, Sander Dijkstra, Andrzej Pieńkowski, Robert Grimer
BACKGROUND: Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive, rarely metastazing bone tumor. This is a retrospective study evaluating a large series of GCTB patients treated with denosumab in routine practice in 6 European reference centers. METHODS: Patients with locally advanced, unresectable or metastatic GCTB, treated with denosumab outside clinical trials were eligible. Primary end-point was progression-free survival (PFS) for all patients; secondary end-points were: type of surgery, relapse rate and event-free survival for patients after preoperative denosumab + surgery...
March 31, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29628687/megaprosthesis-versus-allograft-prosthesis-composite-for-massive-skeletal-defects
#10
REVIEW
Deepak Gautam, Rajesh Malhotra
Massive skeletal defects are encountered in the setting of tumors necessitating excision, failed total hip arthroplasty with periprosthetic bone loss, periprosthetic fracture, complex trauma, multiple failed osteosynthesis and infection. Reconstruction of the segmental defects poses a tremendous challenge to the orthopaedic surgeons. The goal of osseous reconstruction of these defects is to restore the bone length and function. Currently the most commonly employed methods for reconstruction are either a megaprosthesis or an Allograft Prosthesis Composite (APC)...
January 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29600686/-treatment-progress-on-giant-cell-tumors-of-bone
#11
REVIEW
Peng Liang
Giant cell tumors(GCT) of bone is benign bone tumors with aggressive and osteolytic activity. As traditional treatment of GCT, removal of bone graft is disease with high local recurrence rate, and could reduce local recurrence by auxiliary means. Different surgical methods such as prosthesis replacement, wide resection and En-bloc resection could be selected for different parts of giant cell tumor of bone, based on the lesion location, size, extent of invasion, recurrence rate. For patients with special region of GCT of bone with removed incompletely and high surgical risk expected, arterial embolism could be performed...
March 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29593186/peritoneal-cecal-cancer-metastasis-to-a-mesh-plug-prosthesis-a-case-report
#12
Itaru Shigeyoshi, Koji Komori, Takashi Kinoshita, Taihei Oshiro, Seiji Ito, Tetsuya Abe, Yoshiki Senda, Kazunari Misawa, Yuichi Ito, Norihisa Uemura, Seiji Natsume, Eiji Higaki, Byonggu An, Akira Ouchi, Masayuki Tsutsuyama, Takahiro Hosoi, Daisuke Hayashi, Hideharu Tanaka, Tairin Uchino, Aina Kunitomo, Yasuhiro Shimizu
We report the case of a 77-year-old man who presented to our hospital with cecal cancer, lung metastasis, and liver metastasis in January 2013. After four courses of modified infusional intravenous fluorouracil and levofolinate with oxaliplatin (mFOLFOX 6) + bevacizumab, there was no new metastatic lesion and lung metastasis reduction was observed. Ileocecal resection was performed in May, left lower lung lobectomy in August, and extended right posterior segmentectomy + S8 partial liver resection was performed in December...
2018: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/29556273/short-term-outcomes-of-reconstruction-subsequent-to-intercalary-resection-of-femoral-diaphyseal-metastatic-tumor-with-pathological-fracture-comparison-between-segmental-allograft-and-intercalary-prosthesis
#13
Deng-Xing Lun, Yong-Cheng Hu, Xiong-Gang Yang, Feng Wang, Zhao-Wan Xu
Reconstruction of bone defects following femoral diaphyseal tumor resection is challenging. Segmental allograft (SA) and intercalary prosthesis (IP) are the most common reconstruction methods for femoral diaphyseal metastatic tumors with pathological fracture. However, whether the complications and functional outcomes differ between SA and IP remains unclear. To compare the clinical outcomes and complications for patients treated with SA reconstruction or IP replacement for femoral shaft tumors, 34 patients who had undergone intercalary resection for metastatic tumor with pathological fracture in the femoral diaphysis were evaluated...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29549305/trends-and-economic-impact-of-hip-and-knee-arthroplasty-in-central-europe-findings-from-the-austrian-national-database
#14
Lukas Leitner, Silvia Türk, Martin Heidinger, Bernd Stöckl, Florian Posch, Werner Maurer-Ertl, Andreas Leithner, Patrick Sadoghi
Arthroplasty registers were originally established in Scandinavia to receive clinically relevant information from pooled data, to improve quality and reduce revision surgeries, with socioeconomic benefit. In Austria, where the highest rate of total knee arthroplasties (TKA) per inhabitant of all OECD countries was reached in 2014, arthroplasties are centrally reported since 2009. Study purpose was to perform the first analysis of the Austrian database, aiming to obtain data on trends in arthroplasty in Austria over time in relation to demographic development...
March 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29532112/implant-and-limb-survival-after-resection-of-primary-bone-tumors-of-the-lower-extremities-and-reconstruction-with-mega-prostheses-fifty-patients-followed-for-a-mean-of-forteen-years
#15
Christina Enciso Holm, Christian Bardram, Anja Falk Riecke, Peter Horstmann, Michael Mørk Petersen
PURPOSE: Previous studies reported variable outcome and failure rates after mega-prosthetic reconstructions in the lower extremities. The purpose of this study was to make a long-term single-center evaluation of patients treated with limb-sparing surgery and reconstruction with mega-prostheses in the lower extremities. METHODS: We identified 50 patients (osteosarcoma (n = 30), chondrosarcoma (n = 9), osteoclastoma (n = 6), Ewing sarcoma (n = 4), angiosarcoma (n = 1)), who underwent limb-sparing reconstruction of the lower extremities (proximal femur (n = 9), distal femur (n = 29), proximal tibia (n = 9), and the entire femur (n = 3)) between 1985 and 2005...
May 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29521751/polymethyl-methacrylate-custom-made-prosthesis-a-novel-three-dimension-printing-aided-fabrication-technique-for-cranial-and-or-orbital-reconstruction
#16
Pedro Martinez-Seijas, Luis A Díaz-Galvis, Josué Hernando, Ignacio O Leizaola-Cardesa, Antonio Aguilar-Salvatierra, Gerardo Gómez-Moreno
BACKGROUND: Over the years, many materials have been used in orbital reconstruction and cranioplasty. Among the materials in current use, polymethyl methacrylate (PMMA) offers a high degree of compatibility with human tissue. OBJECTIVE: This work describes a new, custom-made, 3D printing-aided, prosthetic fabrication process for orbital and/or cranial reconstruction using PMMA. METHODS: On the basis of information obtained from computerized tomography scanning processed in Digital Imaging and Communication in Medicine format and exported to treatment planning software, a 3D prosthesis master model was designed and digitally printed...
March 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29509540/laparogastroscopy-and-esophageal-stenosis
#17
Alexandru-Dan Sabău, Noor Hassan, Cătălin Gabriel Smarandache, Alin Miheţiu, Ștefan Ţîţu, Dan Sabău
PURPOSE: An original technique using laparoscopic instruments in a gastric endocavitary work chamber with potential for esophagus, stomach and D1 vizualisation. The main purpose of laparagastroscopy is to improve the quality of life of the patient disabling by the esophageal tumor. This method has several advantages: providing physiological feeding, harvesting materials for histopathological examination, solving eso-tracheal fistulas concurrently with the proposed operation and hemostatic role through compression, low energy and plastic consumption, rapid socio-economic reintegration, mental psychological care of the patient...
January 2018: Chirurgia
https://www.readbyqxmd.com/read/29509537/endoscopic-treatment-of-benign-esophageal-fistulas-using-fully-covered-metallic-esophageal-stents
#18
Denisa Oprisanescu, Denisa Bucur, Vasile Sandru, Ioan Cristian Nedelcu, Madalina Ilie, Ruxandra Oprita, Gabriel Constantinescu
Non-malignant esophageal fistulas have a wide spectrum of clinical and pathological features and it`s important to learn to detect and treat them, due to significant morbidity, mortality and costs. The need for minimally invasive, efficient and also quick procedures is imperative. Esophageal stenting using fully-covered expandable stents has become an increasingly preferred option and addresses to fistulas which arise from 2-3 cm beyond Killian's mouth and up to the gastroesophageal junction. The long-term purpose of the procedure is closure of the fistula and thus healing...
January 2018: Chirurgia
https://www.readbyqxmd.com/read/29473959/reconstruction-using-a-constrained-type-hip-tumor-prosthesis-after-resection-of-malignant-periacetabular-tumors-a-study-by-the-japanese-musculoskeletal-oncology-group-jmog
#19
Koichi Ogura, Michiro Susa, Hideo Morioka, Akihiko Matsumine, Takeshi Ishii, Kenichiro Hamada, Takafumi Ueda, Akira Kawai
BACKGROUND: We conducted a nationwide survey of prosthetic reconstruction using a constrained-type hip tumor prosthesis (C-THA) following resection of periacetabular tumors. METHODS: Eighty patients with periacetabular tumors underwent wide resection and prosthetic reconstruction using C-THA at JMOG-affiliated institutions (39 males and 41 females; mean age, 46.7 years; mean follow-up period, 65 months). Primary bone or soft tissue sarcoma accounted for 75% of the cases...
February 23, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29461377/total-lower-lip-reconstruction-with-functional-gracilis-free-muscle-flap
#20
Mehmet Akif Cakmak, Hakan Cinal, Ensar Zafer Barin, Muhammed Sedat Sakat, Harun Karaduman, Onder Tan
Free flaps based on static slings principles cannot provide esthetic and functional outcomes at a desired level in total or close to total lip loss. Therefore, dynamic methods have become a current issue in recent years and especially the idea of functional gracilis free muscle flap has been suggested. In this study, we present a case of a successful total lower lip repair with this flap.In a 78-year-old female patient who was diagnosed with squamous cell carcinoma involving the entire lower lip, bilateral modified radical neck dissection and full-thickness total resection with 1 cm surgical margin so as to include both commissures of the tumor were performed and then a free gracilis muscle flap was transferred from the same side...
May 2018: Journal of Craniofacial Surgery
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