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https://www.readbyqxmd.com/read/28106524/the-utility-of-3d-printing-for-surgical-planning-and-patient-specific-implant-design-for-complex-spinal-pathologies-case-report
#1
Ralph J Mobbs, Marc Coughlan, Robert Thompson, Chester E Sutterlin, Kevin Phan
OBJECTIVE There has been a recent renewed interest in the use and potential applications of 3D printing in the assistance of surgical planning and the development of personalized prostheses. There have been few reports on the use of 3D printing for implants designed to be used in complex spinal surgery. METHODS The authors report 2 cases in which 3D printing was used for surgical planning as a preoperative mold, and for a custom-designed titanium prosthesis: one patient with a C-1/C-2 chordoma who underwent tumor resection and vertebral reconstruction, and another patient with a custom-designed titanium anterior fusion cage for an unusual congenital spinal deformity...
January 20, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28101196/denosumab-treatment-of-inoperable-or-locally-advanced-giant-cell-tumor-of-bone
#2
Aneta Borkowska, Tomasz Goryń, Andrzej Pieńkowski, Michał Wągrodzki, Ewelina Jagiełło-Wieczorek, Paweł Rogala, Milena Szacht, Piotr Rutkowski
Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive tumor that rarely metastasizes and typically occurs in the bones. At present, the primary treatment for GCTB is curettage with local adjuvants. Giant cells express receptor activator of nuclear factor-κB ligand (RANKL). Denosumab, a RANKL inhibitor appears to present an effective therapeutic option in advanced cases of GCTB. The aim of the present study was to confirm the efficacy of denosumab in large group of patients with locally advanced GCTB...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28060092/functional-reconstruction-of-nonsegmental-mandibular-defect-with-fresh-frozen-bone-graft-and-delayed-implants-placement
#3
Tommaso Bucci, Pier Francesco Nocini
The loss of teeth and the alveolar bone secondary to resection of mandibular tumors may lead to unfavorable esthetic and functional results with a significant impairment of mastication.The authors report a 53-year-old patient with recurrence of ameloblastoma who was submitted to marginal mandibulectomy. Bone defect was immediately reconstructed using fresh frozen bone graft and 9 months after reconstruction 3 dental implants were inserted in the grafted bone. After 6 months, dental rehabilitation was achieved using a fixed implant-supported prosthesis...
January 5, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28052811/short-term-outcomes-of-mandibular-reconstruction-in-oncological-patients-using-a-cad-cam-prosthesis-including-a-condyle-supporting-a-fibular-free-flap
#4
Achille Tarsitano, Salvatore Battaglia, Valerio Ramieri, Piero Cascone, Leonardo Ciocca, Roberto Scotti, Claudio Marchetti
PURPOSE: Condylar reconstruction and replacement using alloplastic materials currently attracts much surgical interest. The major challenge is to functionally reconstruct the anatomical region; this is crucial in terms of correct mandibular function. The goal of the present study was to evaluate the clinical outcomes of and complications experienced by a series of oncological patients who underwent computer-aided design/computer-aided manufacturing (CAD/CAM) condylar reconstruction following resection-disarticulation of the mandible...
December 16, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28005771/ocular-reconstruction-using-bone-anchored-implants-in-irradiated-facial-deformities-after-tumor-extirpation
#5
Mansher Singh, Raquel Minasian, Matthew Jackson, E J Caterson
BACKGROUND: Surgical resection of ocular malignancies can result in complex craniofacial defects that can be difficult to reconstruct with conventional reconstruction techniques. Craniofacial prosthesis supported by bone-anchored implants has evolved as a reliable alternative in such scenarios. METHODS: The authors describe a patient who underwent extensive facial resection secondary to squamous cell carcinoma resulting in significant facial deformities. A bone-anchored osseointegrated implant was used to perform facial reconstruction...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005762/jaw-in-a-day-state-of-the-art-in-maxillary-reconstruction
#6
Christopher M Runyan, Vishal Sharma, David A Staffenberg, Jamie P Levine, Lawrence E Brecht, Leonard H Wexler, David L Hirsch
BACKGROUND: Reconstruction of maxillary defects following tumor extirpation is challenging because of combined aesthetic and functional roles of the maxilla. One-stage reconstruction combining osseous free flaps with immediate osseointegrated implants are becoming the standard for mandibular defects, and have similar potential for maxillary reconstruction. METHODS: A woman with maxillary Ewing sarcoma successfully treated at age 9 with neoadjuvant chemotherapy, right hemimaxillectomy, and obturator prosthetic reconstruction presented for definitive reconstruction, complaining of poor obturator fit, and hypernasality...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27989047/results-of-contemporary-valve-surgery-in-patients-with-carcinoid-heart-disease
#7
Thomas Kuntze, Tamer Owais, Maria-Anna Secknus, Daniel Kaemmerer, Richard Baum, Evaldas Girdauskas
BACKGROUND: Carcinoid tumor is a slow-growing type of neuroendocrine tumor, originating from enterochromaffin cells and secreting mainly serotonin. The diagnosis is based on clinical symptoms, hormone blood levels, radiological and nuclear imaging, and histological confirmation. However, most patients have metastases at the time of diagnosis because the clinical signs often remain unnoticed or are attributed to other abdominal conditions. In up to 50% of patients the endocardium is affected due to a hormonally active tumor profile...
May 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27984686/-surgical-treatment-of-malignant-primary-tumors-of-the-pelvis-on-ennekings-zone-ii
#8
A M González-Pérez, C Arvinius, J García-Coiradas, R García-Maroto, J L Cebrian-Parra
INTRODUCTION: Surgical treatment of malignant bone tumors of the pelvis with periacetabular involvement is constantly evolving. Even though acetabular reconstructions improve quality of life without impairing cancer control, they are not complication free. Our purpose is to describe the functional outcomes and surgical complications of different reconstructive techniques for Enneking zone II tumors. MATERIAL AND METHODS: Fifteen patients underwent surgery for malignant pelvic bone tumors between 2002 and 2012...
May 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/27956077/modular-cementless-prosthetic-reconstruction-after-resection-of-lower-extremity-malignant-tumor
#9
Senol Bekmez, Mehmet Ayvaz, Altug Yucekul, Mazhar Tokgozoglu
INTRODUCTION: The aim of the study is to report the preliminary clinical and functional outcomes of a modular cementless tumor resection prosthesis system (Megasystem-C(®), Waldemar Link GmbH&Co. KG, Hamburg, Germany) in patients undergoing limb salvage surgery with wide resection in a lower extremity primary or metastatic malignant bone tumor. MATERIAL AND METHODS: Fifty-two consecutive patients (33 male and 19 female; mean age 37.1 years (range, 16 to 79) with primary or metastatic lower extremity malignant bone tumor who underwent wide resection and reconstruction with cementless Megasystem-C(®) system were included in the study...
December 9, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/27955655/short-to-long-term-follow-up-of-total-femoral-replacement-in-non-oncologic-patients
#10
Andreas Toepfer, Norbert Harrasser, Isabel Petzschner, Florian Pohlig, Ulrich Lenze, Ludger Gerdesmeyer, Dominik Pförringer, Marcel Toepfer, Marc Beirer, Moritz Crönlein, Ruediger von Eisenhart-Rothe, Heinz Mühlhofer
BACKGROUND: Compromised bone stock and heavily impaired structural integrity after multiple endoprosthetic revision surgeries can lead to a comparable condition as encountered in musculoskeletal tumor surgery. Total femoral replacement (TFR) can restore femoral integrity and allow patients to resume ambulation. Even though several authors reported their results of TFR, so far many questions are still on debate: Which patients are at risk to experience low functional outcome? Do complications and clinical outcome after TFR depend on the indication for the surgery (e...
December 12, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27930584/risk-of-infection-is-associated-more-with-drain-duration-than-daily-drainage-volume-in-prosthesis-based-breast-reconstruction-a-cohort-study
#11
Cheng-Feng Chen, Shou-Fong Lin, Chen-Fang Hung, Pesus Chou
In prosthesis-based breast reconstruction, drains are used to prevent seroma formation and to reduce the risk of infection. However, prolonged drainage increases the risk of ascending infection. Although the volume often accepted for drain removal is ≤30 mL per day, the optimal timing to remove the drain for best clinical outcome remains controversial.We did a retrospective cohort study of 569 patients of prosthesis-based breast reconstruction with infection rate as the outcome variable; drain duration and last daily drainage volume as the main independent variables...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27915374/long-term-functional-and-radiological-outcomes-of-allograft-hip-prosthesis-composite-a-fourteen%C3%A2-year-follow-up-study
#12
Arnaud Dubory, Eric Mascard, Méryl Dahan, Philippe Anract, Charles Court, Stéphane Boisgard, Brice Viard, Gilles Missenard
PURPOSE: Allograft hip composite prosthesis (APC) is a type of reconstruction after resection of the proximal femur. This study aimed to assess long-term outcomes after an APC reconstruction. MATERIALS AND METHODS: Forty-six patients were retrospectively included (14 revision total hip replacements, 30 primary malignant bone tumors, two metastasis). RESULTS: The mean length of femoral bone resection was 16.4 cm (7 to 27). With a mean follow-up of 14...
December 3, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27912929/survival-failure-modes-and-function-of-combined-distal-femur-and-proximal-tibia-reconstruction-following-tumor-resection
#13
F Sevelda, W Waldstein, J Panotopoulos, C Stihsen, A Kaider, P T Funovics, R Windhager
BACKGROUND: Tumor spread to the knee joint or skip metastasis to the adjacent bones of the knee require reconstruction with combined distal femur and proximal tibia replacements. The literature on implant survival and failure modes with this type of reconstruction is sparse. The goals of this study were to determine the implant survival, the different failure modes and the functional outcome of this megaendoprosthetic reconstruction. PATIENTS AND METHODS: Thirty-nine patients with combined distal femur and proximal tibia reconstruction were retrospectively reviewed...
November 23, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27909134/what-is-the-morbidity-of-a-non-invasive-growing-prosthesis
#14
M M Gilg, C L Gaston, M C Parry, L Jeys, A Abudu, R M Tillman, S R Carter, R J Grimer
AIMS: Extendible endoprostheses have been available for more than 30 years and have become more sophisticated with time. The latest generation is 'non-invasive' and can be lengthened with an external magnetic force. Early results have shown a worryingly high rate of complications such as infection. This study investigates the incidence of complications and the need for further surgery in a cohort of patients with a non-invasive growing endoprosthesis. PATIENTS AND METHODS: Between 2003 and June 2014, 50 children (51 prostheses) had a non-invasive growing prosthesis implanted for a primary bone sarcoma...
December 2016: Bone & Joint Journal
https://www.readbyqxmd.com/read/27898357/catastrophic-metallosis-after-tumoral-knee-prosthesis-failure-a-case-report
#15
Luca La Verde, Domenico Fenga, Maria Silvia Spinelli, Francesco Rosario Campo, Michela Florio, Michele Attilio Rosa
INTRODUCTION: Metallosis is a condition characterized by an infiltration of periprosthetic soft tissues and bone by metallic debris resulting from wear or failure of joint arthroplasties. PRESENTATION OF CASE: Authors describe a case of a 45-year-old man treated for an osteosarcoma of the distal femur with a modular prosthesis when he was 18 years old, he developed massive metallosis with skin dyspigmentation after 17 years. His medical\surgical history was remarkable for a left tumoral knee prosthesis implanted 21 years ago...
November 18, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27882029/effects-of-comprehensive-rehabilitation-training-in-combination-with-multi-mode-analgesia-on-body-function-recovery-after-tumor-type-knee-replacement
#16
Junjuan Zhang, Yahan Wang, Guangyu Yang, Jing Liu, Junjie Wang
OBJECTIVE: To discuss the significance of comprehensive rehabilitation training combined with multimodal analgesia (MMA) for the early knee function recovery of patients with knee bone tumor who underwent prosthesis replacement operation. METHODS: Sixty patients with knee bone tumor who underwent prosthesis replacement operation were selected and randomly divided into two groups according to rehabilitation training and postoperative analgesic methods, namely, observation group and control group, 30 cases in each group...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27881310/implant-retained-skull-prosthesis-to-cover-a-large-defect-of-the-hairy-skull-resulting-from-treatment-of-a-basal-cell-carcinoma-a-clinical-report
#17
Jitske Hoekstra, Arjan Vissink, Gerry M Raghoebar, Anita Visser
Skin carcinoma, particularly basal cell carcinoma, and its treatment can result in large defects of the hairy skull. A 53-year-old man is described who was surgically treated for a large basal cell carcinoma invading the skin and underlying tissue at the top of the hairy skull. Treatment consisted of resecting the tumor and external part of the skull bone. To protect the brain and to cover the defect of the hairy skull, an acrylic resin skull prosthesis with hair was designed to mask the defect. The skull prosthesis was retained on 8 extraoral implants placed at the margins of the defect in the skull bone...
October 27, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27879144/-recurrent-retroperitoneal-sarcoma
#18
J Dítě, J Froněk
Retroperitoneal sarcomas are rare malignant neoplasms that are often diagnosed late because of their typical nonspecific symptomatology. Radical surgical resection, if possible given the local anatomical conditions, is the most important treatment modality. However, even if the surgery is feasible and successful, the prognosis of retroperitoneal sarcoma is not good. The most frequent type of recurrence is local recurrence, and radical surgical resection remains the most important treatment modality even in such cases...
2016: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/27871294/newly-designed-retentive-posts-of-mandibular-reconstruction-plate-in-oral-cancer-patients-based-on-preliminary-fem-study
#19
Ik Jae Kwon, Mi Young Eo, Sung Jae Park, Soung Min Kim, Jong Ho Lee
BACKGROUND: The reconstruction of a large mandibular defect poses a challenging issue in oral cancer ablation surgery. One popular option for mandibular continuity reconstruction after tumor resection involves the use of a reconstruction plate (R-plate), which maintains space and contour without bone harvesting. An R-plate, however, cannot provide final functional loading rehabilitation with implants or dentures. METHODS: We suggest a new method of functional mandibular reconstruction using retentive posts and an upper prosthesis...
November 21, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27826392/prosthetic-reconstruction-with-an-obturator-using-swing-lock-attachment-for-a-patient-underwent-maxillectomy-a-clinical-report
#20
Dong-Jae Seong, Seoung-Jin Hong, Seung-Ryong Ha, Young-Gi Hong, Hyo-Won Kim
Patients who underwent resection of maxilla due to benign or malignant tumor, or accident will have defect in palatal area. They get retention, support and stability from remaining tissues which are hardly optimal. The advantage of swing-lock attachment design is having multiple contacts on labial and lingual side of the abutment teeth by retentive strut and palatal bracing component. Because the force is distributed equally to abutment teeth, abutment teeth of poor prognosis can be benefited from it. It is also more advantageous to cover soft tissue defects which are hard to reach with conventional prosthesis...
October 2016: Journal of Advanced Prosthodontics
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