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https://www.readbyqxmd.com/read/28731411/oral-immunotherapy-for-food-allergy-a-spanish-guideline-immunotherapy-egg-and-milk-spanish-guide-items-guide-part-i-cow-milk-and-egg-oral-immunotherapy-introduction-methodology-rationale-current-state-indications-contraindications-and-oral-immunotherapy-build
#1
A Martorell, E Alonso, L Echeverría, C Escudero, R García-Rodríguez, C Blasco, J Bone, J Borja-Segade, T Bracamonte, A Claver, J L Corzo, B De la Hoz, R Del Olmo, O Dominguez, V Fuentes-Aparicio, I Guallar, H Larramona, F Martín-Muñoz, V Matheu, A Michavila, I Ojeda, P Ojeda, M Piquer, P Poza, M Reche, P Rodríguez Del Río, M Rodríguez, F Ruano, S Sánchez-García, S Terrados, L Valdesoiro, M Vazquez-Ortiz
BACKGROUND AND OBJECTIVE: Cow milk and egg are the most frequent causes of food allergy in the first years of life. Oral immunotherapy (OIT) has been investigated as an alternative to avoidance diets. No clinical practice guidelines on the management of OIT with milk and egg are currently available. Objectives: To develop clinical guidelines for OIT based on available scientific evidence and the opinions of experts. METHODS: A review was made of studies published between 1984 and June 2016, doctoral theses published in Spain, summaries of communications at scientific meetings (SEAIC, SEICAP, EAACI, and AAAAI), and the consensus of opinion established by a group of experts from the scientific societies SEICAP and SEAIC...
2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/28730348/-pharyngoesophageal-diverticulum
#2
C A Gutschow, P Bauerfeind
Over the last 20-30 years, treatment of pharyngoesophageal diverticula was subject to a number of fundamental changes. Considering the classical open transcervical approaches, the necessity for myotomy of the upper esophageal sphincter with the goal of interrupting the pathogenesis of the disease has become a standard component of the operation. On the other hand, with the growing popularity of rigid and flexible endoscopic techniques, pharyngoesophageal diverticula are increasingly being treated by gastroenterologists and otorhinolaryngologists, often with the argument of a technically easier and less invasive procedure; however, it remains unclear whether this shift towards endoscopic techniques truly translates into better outcome quality...
July 20, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28730221/usefulness-of-ultrastructure-studies-for-the-estimation-of-the-postmortem-interval-a-systematic-review
#3
Sorin Hostiuc, Mugurel Constantin Rusu, Vasile Sorin Mănoiu, Alexandra Diana Vrapciu, IonuŢ Negoi, Maria Viorela Popescu
Establishing the postmortem interval (PMI) is vital in legal medicine as it allows to retrospectively estimate the hour of death, which is essential for the police as a starting point for their inquiries (especially in violent deaths). Ultrastructure studies aimed specifically to detect autolytic changes are scarcely identified in the scientific literature. Moreover, they are performed in a variety of conditions (different temperatures, species, in vitro ÷ in situ, and so on), making the results difficult to interpret for legal medicine purposes...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28729228/tangled-history-of-the-european-uses-of-sphagnum-moss-and-sphagnol
#4
REVIEW
Jacek Drobnik, Adam Stebel
ETHNOPHARMACOLOGICAL RELEVANCE: Sphagnum mosses and peat could have been utilized as wound dressings for centuries, however reliable data on this subject are ambiguous; sometimes even no distinction between peat moss (Sphagnum spp.) and peat is made or these terms become confused. The first scientific account on surgical use of peat comes from 1882: a peat digger who successfully, by himself and in the way unknown to the then medicine, cured an open fracture of his forearm with peat. The peat, and very soon the peat moss itself (which is the major constituent of peat) drew attention of the 19(th)-century surgeons...
July 17, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28727961/psychology-s-replication-crisis-and-the-grant-culture-righting-the-ship
#5
Scott O Lilienfeld
The past several years have been a time for soul searching in psychology, as we have gradually come to grips with the reality that some of our cherished findings are less robust than we had assumed. Nevertheless, the replication crisis highlights the operation of psychological science at its best, as it reflects our growing humility. At the same time, institutional variables, especially the growing emphasis on external funding as an expectation or de facto requirement for faculty tenure and promotion, pose largely unappreciated hazards for psychological science, including (a) incentives for engaging in questionable research practices, (b) a single-minded focus on programmatic research, (c) intellectual hyperspecialization, (d) disincentives for conducting direct replications, (e) stifling of creativity and intellectual risk taking, (f) researchers promising more than they can deliver, and (g) diminished time for thinking deeply...
July 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28727896/proseal-versus-classic-laryngeal-mask-airway-lma-for-positive-pressure-ventilation-in-adults-undergoing-elective-surgery
#6
REVIEW
Muhammad Qamarul Hoda, Khalid Samad, Hameed Ullah
BACKGROUND: The development of supraglottic airway devices has revolutionized airway management during general anaesthesia. Two devices are widely used in clinical practice to facilitate positive pressure ventilation: the ProSeal laryngeal mask airway (pLMA) and the Classic laryngeal mask airway (cLMA). It is not clear whether these devices have important clinical differences in terms of efficacy or complications. OBJECTIVES: To compare the effectiveness of the ProSeal laryngeal mask airway (pLMA) and the Classic LMA (cLMA) for positive pressure ventilation in adults undergoing elective surgery...
July 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28727700/therapeutic-role-of-placebo-evolution-of-a-new-paradigm-in-understanding-research-and-clinical-practice
#7
Laxmaiah Manchikanti, Mark V Boswell, Alan D Kaye, Standiford Helm Ii, Joshua A Hirsch
Research into interventional techniques in managing chronic spinal pain continues to be challenging, mystifying, confusing, and biased. Insight, or lack thereof, into placebo and nocebo phenomena contributes mightily to these difficulties. Unfortunately, placebo-nocebo responses are the subject of numerous controversies and challenges from not only a research perspective, but also clinical perspective. While interventionalists consider the biggest threat to interventional pain management research is inappropriate and outdated interpretation of the data, a greater problem is the misuse of the placebo response in research, with the declaration that all and everything as a placebo effect: with a misinterpretation of the nature of the placebo the, associated conclusions can be inaccurate...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28726868/raman-spectroscopy-for-cancer-detection-and-cancer-surgery-guidance-translation-to-the-clinics
#8
REVIEW
Inês P Santos, Elisa M Barroso, Tom C Bakker Schut, Peter J Caspers, Cornelia G F van Lanschot, Da-Hye Choi, Martine F van der Kamp, Roeland W H Smits, Remco van Doorn, Rob M Verdijk, Vincent Noordhoek Hegt, Jan H von der Thüsen, Carolien H M van Deurzen, Linetta B Koppert, Geert J L H van Leenders, Patricia C Ewing-Graham, Helena C van Doorn, Clemens M F Dirven, Martijn B Busstra, Jose Hardillo, Aniel Sewnaik, Ivo Ten Hove, Hetty Mast, Dominiek A Monserez, Cees Meeuwis, Tamar Nijsten, Eppo B Wolvius, Robert J Baatenburg de Jong, Gerwin J Puppels, Senada Koljenović
Oncological applications of Raman spectroscopy have been contemplated, pursued, and developed at academic level for at least 25 years. Published studies aim to detect pre-malignant lesions, detect cancer in less invasive stages, reduce the number of unnecessary biopsies and guide surgery towards the complete removal of the tumour with adequate tumour resection margins. This review summarizes actual clinical needs in oncology that can be addressed by spontaneous Raman spectroscopy and it provides an overview over the results that have been published between 2007 and 2017...
July 20, 2017: Analyst
https://www.readbyqxmd.com/read/28726804/diagnostic-cytogenetic-testing-following-positive-noninvasive-prenatal-screening-results-a-clinical-laboratory-practice-resource-of-the-american-college-of-medical-genetics-and-genomics-acmg
#9
Athena M Cherry, Yassmine M Akkari, Kimberly M Barr, Hutton M Kearney, Nancy C Rose, Sarah T South, James H Tepperberg, Jeanne M Meck
Disclaimer: ACMG Clinical Laboratory Practice Resources are developed primarily as an educational tool for clinical laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these practice resources is voluntary and does not necessarily assure a successful medical outcome. This Clinical Laboratory Practice Resource should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results...
July 20, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28726479/motivational-interviewing-and-the-clinical-science-of-carl-rogers
#10
William R Miller, Theresa B Moyers
The clinical method of motivational interviewing (MI) evolved from the person-centered approach of Carl Rogers, maintaining his pioneering commitment to the scientific study of therapeutic processes and outcomes. The development of MI pertains to all 3 of the 125th anniversary themes explored in this special issue. Applications of MI have spread far beyond clinical psychology into fields including health care, rehabilitation, public health, social work, dentistry, corrections, coaching, and education, directly impacting the lives of many people...
August 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28726028/should-we-all-be-scientists-re-thinking-laboratory-research-as-a-calling
#11
Louise Bezuidenhout, Nathaniel A Warne
In recent years there have been major shifts in how the role of science-and scientists-are understood. The critical examination of scientific expertise within the field of Science and Technology Studies (STS) are increasingly eroding notions of the "otherness" of scientists. It would seem to suggest that anyone can be a scientist-when provided with the appropriate training and access to data. In contrast, however, ethnographic evidence from the scientific community tells a different story. Scientists are quick to recognize that not everyone can-or should-be a scientist...
July 19, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28725263/modeling-and-simulation-of-the-redox-regulation-of-the-metabolism-in-escherichia-coli-at-different-oxygen-concentrations
#12
Yu Matsuoka, Hiroyuki Kurata
BACKGROUND: Microbial production of biofuels and biochemicals from renewable feedstocks has received considerable recent attention from environmental protection and energy production perspectives. Many biofuels and biochemicals are produced by fermentation under oxygen-limited conditions following initiation of aerobic cultivation to enhance the cell growth rate. Thus, it is of significant interest to investigate the effect of dissolved oxygen concentration on redox regulation in Escherichia coli, a particularly popular cellular factory due to its high growth rate and well-characterized physiology...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28725209/a-national-early-intervention-system-as-a-strategy-to-promote-inclusion-and-academic-achievement-in-portugal
#13
Vitor Franco, Madalena Melo, Graça Santos, Ana Apolónio, Leonor Amaral
Early intervention with children at risk or facing developmental problems is a practice defined by three fundamental characteristics: being family-centered, being based on the community and on the child's life context, and being conducted by a team with transdisciplinary practice. In this paper we wish to present how the SNIPI-National System of Early Intervention, implemented in Portugal over the past 15 years, contributes to promote maximum development and the full inclusion of children up to 6 years of age and works to prevent school failure...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28725096/quality-assessment-of-scientific-outputs-using-the-bwm
#14
Negin Salimi
Assessing the quality of scientific outputs (i.e. research papers, books and reports) is a challenging issue. Although in practice, the basic quality of scientific outputs is evaluated by committees/peers (peer review) who have general knowledge and competencies. However, their assessment might not comprehensively consider different dimensions of the quality of the scientific outputs. Hence, there is a requirement to evaluate scientific outputs based on some other metrics which cover more aspects of quality after publishing, which is the aim of this study...
2017: Scientometrics
https://www.readbyqxmd.com/read/28725095/with-whom-do-researchers-collaborate-and-why
#15
Hajdeja Iglič, Patrick Doreian, Luka Kronegger, Anuška Ferligoj
Although research collaboration has been studied extensively, we still lack understanding regarding the factors stimulating researchers to collaborate with different kinds of research partners including members of the same research center or group, researchers from the same organization, researchers from other academic and non-academic organizations as well as international partners. Here, we provide an explanation of the emergence of diverse collaborative ties. The theoretical framework used for understanding research collaboration couples scientific and technical human capital embodied in the individual with the social organization and cognitive characteristics of the research field...
2017: Scientometrics
https://www.readbyqxmd.com/read/28724483/using-white-tailed-deer-odocoileus-virginianus-in-infectious-disease-research
#16
Mitchell V Palmer, Rebecca J Cox, W Ray Waters, Tyler C Thacker, Diana L Whipple
Between 1940 and 2004, more than 335 emerging infectious disease events were reported in the scientific literature. The majority (60%) of these events involved zoonoses, most of which (72%) were of wildlife origin or had an epidemiologically important wildlife host. Because this trend of increasing emerging diseases likely will continue, understanding the pathogenesis, transmission, and diagnosis of these diseases in the relevant wildlife host is paramount. Achieving this goal often requires using wild animals as research subjects, which are vastly different from the traditional livestock or laboratory animals used by most universities and institutions...
July 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28724181/finding-the-best-therapeutic-approach-for-pcos-the-importance-of-inositol-s-bioavailability
#17
B Orrù, R Circo, P Logoteta, S Petousis, G Carlomagno
Broadening clinical evidence has markedly designated inositol(s) as a common and effective therapeutic approach for PCOS and infertility. Although considerable research has been focused on the use in clinical practice of myo-inositol (myo-ins) and D-chiro-inositol (D-chiro-ins), the two major inositol stereoisomers, less attention has been paid to their bioavailability. Therefore, the aim of this paper is to gather and analyze information on inositol(s) bioavailability, to better delineate its optimal concentration for scientific and clinical purposes...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28722346/progress-of-large-scale-synthesis-and-electronic-device-application-of-two-dimensional-transition-metal-dichalcogenides
#18
REVIEW
Xiongfei Song, Zhongxun Guo, Qiaochu Zhang, Peng Zhou, Wenzhong Bao, David Wei Zhang
The recent exploration of semiconducting two-dimensional (2D) transition metal dichalcogenides (TMDs) with atomic thickness has taken both the scientific and technological communities by storm. Extensively investigated TMD that are accessible by large-scale synthetic methods materials are remarkably stable, such as MoS2 and WSe2 . They allow superior gate control due to their 2D nature and favorable electronic transport properties, thus suggesting a bright future for digital and RF electronics. In this review, the latest developments in the controlled synthesis of large scale TMDs are firstly introduced by discussing various approaches...
July 19, 2017: Small
https://www.readbyqxmd.com/read/28722310/capitalizing-on-scientific-advances-to-improve-access-to-and-quality-of-children-s-mental-health-care
#19
Ann F Garland, Florencia Lebensohn-Chialvo, Kristopher G Hall, Erika R N Cameron
The majority of mental health problems begin in childhood or adolescence. The potential benefits of early identification and treatment of such problems are well established, and models of effective mental health interventions for children have proliferated in recent decades. However, barriers in access to care and challenges in assuring delivery of high-quality care significantly limit the public health impact of services for children and families. Specifically, the majority of children who need mental health care do not receive it, and when children are in care, many do not receive interventions that are most likely to have the greatest positive impact...
July 19, 2017: Behavioral Sciences & the Law
https://www.readbyqxmd.com/read/28722088/-evaluation-of-new-minimally-invasive-techniques-in-gastrointestinal-surgery-and-contemplation-on-health-economics
#20
Xishan Wang
With the widespread introduction of minimally invasive surgery (MIS) in late 1987 by laparoscopic cholecystectomy, the practice and expectation of general surgery were changed forever. As the development of scientific technology, new techniques of MIS have sprung up all around the world. 3D laparoscopy surgery, natural orifice transluminal endoscopic surgery, da Vinci surgical system and other new technologies also need time to be verified, and this is the only way all new things should get though. They are very unique in their own right, and all have advantages and disadvantages...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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